Clinical trials: Malocclusion
Malocclusion, Angle Class III
Evaluation of Surgical Outcomes of Patients Treated With the Surgery First Approach and Aligners
The purpose of this prospective study is to compare treatment outcomes and the quality of life of skeletal Class III patients treated with conventional fixed appliances and aligners undergoing Surgery-first approach.
- Trial name
- NCT05822271
- Testing
- Orthognathic Surgery
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Malocclusion
Three- Dimensional Evaluation of Accelerated Tooth Movement
The purpose of this research study is to assess the clinical effectiveness of a minimally invasive alveolar microperforation procedure to achieve accelerated tooth movement in patients undergoing orthodontic treatment for…
- Trial name
- NCT02416297
- Testing
- Micro-osteoperforation
- Where
- Brazil
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- LIANA FATTORI ABATI
Anterior Open Bite Malocclusion
Stability of Anterior Open Bite Treatment Using Extrusion Arches
This study investigated treatment effects and stability of anterior open bite cases using extrusion arches
- Trial name
- NCT05599074
- Testing
- extrusion arch
- Where
- Egypt
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Malocclusion, Angle Class I, Bimaxillary Protrusion
3D Comparison of Anterior Teeth Retraction and Anchorage Control Between En-masse and Two-step Mechanics
The aim of this study is to compare en masse (EM) and two-step anterior teeth retraction (TSR) evaluated by means of three-dimensional images superimposition.
- Conditions
- Malocclusion, Angle Class I, Bimaxillary Protrusion, Orthodontic Space Closure
- Trial name
- NCT03903575
- Testing
- En masse anterior teeth retraction, Two-Step Retraction
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Obstructive Sleep Apnea, Malocclusion
Premolar Extractions for Obstructive Sleep Apnea in Children With Overjet
This research aims to provide pediatric patients with polysomnography (a sleep study) before and after orthodontic treatment to determine if the extraction of upper premolars for treating excessive overjet results in an increase…
- Trial name
- NCT04946201
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mohamed Bazina
Angle Class I
Effectives of Non-extraction Orthodontic Treatment of Angle Class I Malocclusion
Introduction: The investigators aimed to evaluate the effectiveness of non-extraction orthodontic treatment for Angle class I malocclusion.
- Trial name
- NCT06638983
- Testing
- Non-extraction Orthodontic Treatment of Angle Class I Malocclusion
- Where
- Vietnam
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Malocclusion
Periodontally Accelerated Osteogenic Orthodontics With BMP2
rhBMP-2 has the potential to function as a regenerative material in periodontally accelerated osteogenic orthodontics (PAOO). This study aimed to assess the effects of PAOO with BMP-2 on outcomes such as treatment period, bone…
- Trial name
- NCT03396900
- Testing
- RhBMP-2 Protein, Recombinant, Conventional Corticotomy
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
Malocclusion Class I
Diode Laser Versus LED for Maxillary Canine Retraction in Orthodontic Patients
This study aims to compare the effects of diode laser and light-emitting diode (LED) photobiomodulation on maxillary canine retraction during fixed orthodontic treatment.
- Trial name
- NCT07810699
- Testing
- Diode Laser Photobiomodulation, LED Photobiomodulation
- Where
- Vietnam
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Malocclusion
Comparison of Acupressure, Ibuprofen, and Chewing Gum for the Management of Post-Archwire Orthodontic Pain
The goal of this clinical trial is to find out which method works best to reduce pain after braces are adjusted for the first time (when the first archwire is placed).
- Trial name
- NCT07638644
- Testing
- Acupressure, Ibuprofen 400 mg (if necessary), Chewing Gum
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Bahria University
Skeletal Class III Malocclusion
Evaluation of Treatment Outcomes With Palatal Plate Versus Conventional Tooth Borne Anchorage in Class III Patients
evaluation of treatment outcomes with palatal plate versus conventional tooth borne anchorage in class III patients
- Trial name
- NCT07360509
- Testing
- treatment of skeletal class III by maxillary advancement using transpalatal arch and face mask, treatment of skeletal class III by maxillary advancement using palatal plate and face mask
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Faculty of Dental Medicine for Girls
Malocclusion, Angle Class II
Effect of Photobiomodulation by 808nm Diode Laser on the Stability of Orthodontic Mini-implants.
The study aimed to evaluate the influence of a 635nm diode laser on the stability of orthodontic mini-implants in vitro, as well as mini-implants failure rate (mini-implant loss) and patients pain level after the treatment.
- Trial name
- NCT04276402
- Testing
- Irradiation of implants with 808nm laser
- Where
- Poland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Anterior Open Bite Malocclusion
Efficiency of Microosteoperforation for Accelerating Posterior Segment Intrusion in Skeletal Open Bite Cases
This clinical trial aimed to assess the efficiency of micro-osteoperforation for accelerating posterior intrusion in open bite cases.
- Trial name
- NCT07761065
- Testing
- Micro-osteoperforation, Conventional posterior segment intrusion
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Angle Class I Malocclusion, Dental Crowding
Clinical Performance of Direct-Printed Versus Thermoformed Aligners
The goal of this study is to evaluate and compare the clinical effectiveness of in-office directly 3D-printed clear aligners versus conventional multilayered thermoformed aligners.
- Conditions
- Angle Class I Malocclusion, Dental Crowding, Tooth Spacing
- Trial name
- NCT07637227
- Testing
- Direct-Printed Aligner, Thermoformed aligner
- Where
- 3 sites in Iraq
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Dental Malocclusion
Pain and Activity Levels After Orthodontic Separators
The primary aim of this study is to evaluate the reported pain intensity following placement of Orthodontic separators on healthy volunteers aged 15-49 in relation to their recorded physical activity level.
- Trial name
- NCT05615688
- Testing
- Pain Intensity following Placement of Orthodontic Separators
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Lina Sharab
Skeletal Class II Malocclusion, Mandibular Retrognathia
Fixed Versus Conventional Twin Block Appliances for Skeletal Class II Malocclusion
This study compares two types of dental appliances a fixed Twin Block appliance and a conventional (removable) Twin Block appliance used to treat a bite problem called skeletal Class II malocclusion in growing children and…
- Trial name
- NCT07687927
- Testing
- Conventional Twin Block Appliance
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Malocclusion
EXD-959 Orthodontic Brackets and EXD-961 Related Instruments Trial
The purpose of this study is to assess the performance of the EXD-959 self-ligating ceramic bracket system using EXD 961 instruments in the treatment of orthodontic malocclusion.
- Trial name
- NCT03606551
- Testing
- EXD-959 Bracket System
- Where
- 5 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- 3M
Malocclusion
A Comparison of the Alignment Achieved Using Computer-guided Indirect Bonding of Orthodontic Brackets to Conventional Appliance Placement
Technological advances have made computer aided orthodontic treatment planning possible. 3D dental scanners and software make it possible to design and approve the outcome before treatment begins.
- Trial name
- NCT02221856
- Testing
- Motion View, Conventional Orthodontic Treatment
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Harvard School of Dental Medicine
Tooth Crowding, Dental Crowding
Analysis of Orthodontic Tooth Movement Using 3D Imaging
Purpose: This project aims to study the effects of wire dimension and ligation method (bracket type) on the first stage of orthodontic treatment using 3D imaging.
- Conditions
- Tooth Crowding, Dental Crowding, Malocclusion
- Trial name
- NCT03398798
- Testing
- .014", .016", Twin brackets
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Malocclusion
OrthoPulse 2.0 and 2.1 Feasibility Evaluation
OrthoPulse is a device that uses near-infrared light therapy in order to decrease orthodontic treatment time. The aim of this study is to evaluate OrthoPulse products modified with extended arrays, OrthoPulse 2.0 and OrthoPulse…
- Trial name
- BX13 (NCT03683017)
- Testing
- OrthoPulse 2.0, OrthoPulse 2.1, Invisalign 3.5 Day Wear
- Where
- 7 sites in United States, Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Biolux Research Holdings, Inc.
Malocclusion, Angle Class II, Malocclusion, Angle Class III
Facial Aesthetic Analysis Model Based on Clinical Cohort Phenotype to Explore 45° Facial Profile.
Facial aesthetics has always been a complex and subjective concept. The overall facial harmony, along with lip protrusion, which is often a focus for orthodontists, requires evaluation from multiple perspectives.
- Trial name
- NCT06984666
- Testing
- language
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Linyu Xu