Clinical trials: Malocclusions, open to volunteers
Malocclusion
Digital vs. Conventional Indirect Bonding.
This randomized split-mouth clinical trial will compare digital and conventional indirect bonding techniques for fixed orthodontic bracket placement in adolescent patients requiring treatment in both dental arches.
- Trial name
- NCT07692880
- Testing
- digital indirect bonding technique, conventional indirect bonding technique
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Class II Malocclusion, Mandibular Deficiency
Dentoskeletal Effects of 3D-Printed Fixed Twin Block Versus MARA Appliances in Management of Skeletal Class II
Objective: to evaluate the dentoskeletal effects of CAD/CAM 3D-Printed fixed twin block versus MARA appliances in the management of skeletal class II due to Mandibular Deficiency in Preadolescence Class II malocclusion is…
- Trial name
- NCT07340242
- Testing
- MARA appliance, fixed twin block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Adenoid Hypertrophy, Masseter Muscle
Evaluation of the Effect of Adenoid Hypertrophy on the Masseter Muscle in Children: A Comparative Ultrasonographic Study
The goal of this observational study is to evaluate the effect of adenoid hypertrophy on the masseter muscle in children aged 3 to 8 years.
- Conditions
- Adenoid Hypertrophy, Masseter Muscle, Malocclusion
- Trial name
- NCT07094581
- Testing
- USG
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Melis AKYILDIZ
CLASS II DIVISION 1 MALOCCLUSION, Class II Malocclusion
The Effectiveness of the Twin Block and Carriere Motion Appliances in Post-pubertal Patients and an Evaluation of the Impact of Class II Malocclusion and Its Correction on Oral Health-related Quality of Life
The investigators of this clinical trial aim to: Compare the effectiveness and efficiency of Clark's Twin Block Appliance (CTB) vs Carriere Motion Appliance (CMA) in correcting Class II malocclusion when used in post-pubertal…
- Conditions
- CLASS II DIVISION 1 MALOCCLUSION, Class II Malocclusion, Growth, Overjet
- Trial name
- NCT07292636
- Testing
- CTB, CMA
- Where
- Ireland
- Volunteers
- 88 people
- Sponsor
- Aslam Alkadhimi
Mandibular Growth Stimulation
Comparison of Skeletal Effects of Herbst and Invisalign MA in Growing Patients With KLass II Malocclusion
This study aims to determine and compare the precise skeletal dental and soft tissue effect of Mandibular advancement aligners and Herbst Appliance.
- Trial name
- NCT06409923
- Testing
- Stimulation of mandibular growth.
- Where
- 2 sites in Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Université Libre de Bruxelles
Clear Aligner Appliance
Evaluation of the Efficacy of Injectable Platelet-rich Plasma in Tooth Movement Acceleration With Clear Aligner
Aim of the study is evaluation of the efficacy of injectable platelet-rich plasma in orthodontic tooth movement acceleration with clear aligner
- Trial name
- NCT07103551
- Testing
- Platelet-rich plasma
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Angle Class I Malocclusion, Dental Crowding
Clinical Performance of Direct-Printed Versus Thermoformed Aligners
The goal of this study is to evaluate and compare the clinical effectiveness of in-office directly 3D-printed clear aligners versus conventional multilayered thermoformed aligners.
- Conditions
- Angle Class I Malocclusion, Dental Crowding, Tooth Spacing
- Trial name
- NCT07637227
- Testing
- Direct-Printed Aligner, Thermoformed aligner
- Where
- 3 sites in Iraq
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Malocclusion, Class II Malocclusion
Treatment of Mild Class II Malocclusion in Adult Patients With Clear Aligners Versus Fixed Multibracket Therapy
Patient with class ii division 1 malocclusion who have mild increased overjet will be treated in this study. The efficacy of clear aligners in the treatment of Class II division 1 Malocclusion Using Intermaxillary Elastics will…
- Trial name
- malocclusion (NCT05684510)
- Testing
- clear aligners, traditional treatment Fixed appliances with class II elastics.
- Where
- Syria
- Volunteers
- 24 people
- Sponsor
- Hama University
Malocclusion
Validation of AI-Based Cephalometric Analysis in Orthodontics
This study is designed to evaluate whether artificial intelligence can analyze cephalometric images in orthodontics as a reliable tool for diagnosis and treatment planning.
- Trial name
- AI-CEPH (NCT07315152)
- Testing
- Artificial Intelligence-Driven Cephalometric Analysis
- Where
- Egypt
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Malocclusion, Misaligned Teeth
Optimizing Orthodontic Appliances Efficiency With Remote Dental Monitoring and Artificial Intelligence Algorithms
The decision on aligner changing is based on orthodontists' personal experience and common knowledge that an approximated time span for the aligner have exhausted its biological efficacy.
- Trial name
- NCT05573308
- Testing
- Clear Aligners with Dental Monitoring, Clear Aligners
- Where
- 4 sites in United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Deep Bite Malocclusion, Intrusion of Tooth
Maxillary Incisor Intrusion Using Utility Arch Assisted With Micro-osteoperforations
Study will be directed to evaluate the dentoalveolar changes following maxillary incisor intrusion using utility arch assisted with micro-osteoperforations in deep bite cases.
- Conditions
- Deep Bite Malocclusion, Intrusion of Tooth, Orthodontic Tooth Movement, Root Resorption
- Trial name
- MOPs (NCT07566676)
- Testing
- Micro-osteoperforations, Utility arch
- Where
- Egypt
- Volunteers
- 18 people
- Sponsor
- Al-Azhar University
Dentofacial Deformities, Malocclusions
Changes in Depression and Esthetic Perception After Orthognathic Surgery
This study aims to evaluate changes in depressive symptoms and subjective esthetic perception before and after bimaxillary orthognathic surgery in patients with different types of malocclusion.
- Conditions
- Dentofacial Deformities, Malocclusions, Orthognathic Surgery
- Trial name
- NCT07702448
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people
- Sponsor
- Kırıkkale University
Bite, Orthodontics
Evaluation of a Novel Lip Bumper With Integrated Distal Shoe Appliance in Preventing Second Molar Impaction in Children With Anterior Deep Bite
The goal of this clinical trial is to evaluate the effectiveness of a novel lip bumper with an integrated distal shoe in preventing second molar impaction in children aged 8-10 years with anterior open bite during the mixed…
- Trial name
- Novel Lip Bump (NCT07015385)
- Testing
- Lip Bumper with Integrated Distal Shoe, Conventional Lip Bumper
- Volunteers
- 40 people
- Sponsor
- Dar Al Uloom University
Malocclusion, Orthodontic Tooth Movement
Micro-osteoperforation Versus Photobiomodulation Therapy for Accelerating Maxillary Canine Retraction
Orthodontic treatment often requires moving the upper canine teeth (the pointed teeth) into the spaces left after removing premolar teeth.
- Conditions
- Malocclusion, Orthodontic Tooth Movement, Maxillary Canine Retraction
- Trial name
- MOP-PBMT (NCT07658235)
- Testing
- Micro-osteoperforation (MOP), Photobiomodulation Therapy using 976 nm Diode Laser, Conventional orthodontic canine retraction
- Where
- Iraq
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kufa University
Malocclusion
Comparison of Outcome of Safe T Separators and Conventional Elastomeric Separators
All participants in this study will be provided with information concerning the study's objectives, and benefits associated with participation.
- Trial name
- NCT07119814
- Testing
- Conventional Separators placement, Safe T separator
- Where
- Pakistan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Khyber College of dentistry
Orthodontic Miniscrew Survival, Malocclusion
This RCT Compares the Clinical Performance, Stability, and Patient Perception of Different Diameters Orthodontic Miniscrews in the Posterior Maxilla Buccal Side.
Researchers will compare miniscrews with diameters of 1.3 millimeters and 1.6 millimeters. Both sizes are 8 millimeters long and will be placed between the roots of the first and second molar teeth at the back of the upper jaw.
- Trial name
- RCT (NCT07868705)
- Testing
- Orthodontic miniscrew, 1.3-mm diameter and 8-mm length, Orthodontic miniscrew, 1.6-mm diameter and 8-mm length
- Where
- Malaysia
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Malocclusion; Displaced Teeth
3-D Evaluation of Alveolar Bone Changes and Root Resorption After Traction of Buccally Displaced Maxillary Canines
This clinical study used CBCT images to investigate the alveolar bone changes and root resorption in unilateral buccally displaced maxillary canines and adjacent teeth before and after orthodontic traction of unilateral BDMCs.
- Trial name
- BDMC (NCT07399197)
- Testing
- T-loop, Piggyback double wire
- Where
- Yemen
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sana'a University
Skeletal Class III Malocclusion, Transverse Maxillary Deficiency
Effects of Invisalign Palatal Expander vs Rapid Palatal Expander With Facemask in Growing Class III Patients
The goal of this clinical trial is to compare two types of palatal expanders used with a facemask in children who have skeletal Class III and a narrow upper jaw.
- Trial name
- NCT07485478
- Testing
- Invisalign Palatal Expander (IPE), Rapid Palatal Expander (RPE)
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Mahidol University
Malocclusion, Angle Class III
Evaluation of Surgical Outcomes of Patients Treated With the Surgery First Approach and Aligners
The purpose of this prospective study is to compare treatment outcomes and the quality of life of skeletal Class III patients treated with conventional fixed appliances and aligners undergoing Surgery-first approach.
- Trial name
- NCT05822271
- Testing
- Orthognathic Surgery
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Orthodontic Relapse, Malocclusion
3D-Printed vs Conventional Fixed Retainers After Orthodontic Treatment
This randomized clinical trial aims to compare the clinical performance of two types of three-dimensionally printed fixed retainers (Cobalt-Chromium and Titanium Grade 5) with the conventional multistranded stainless steel fixed…
- Trial name
- NCT07730476
- Testing
- Conventional Multistranded Stainless Steel Fixed Retainer, 3D-Printed Cobalt-Chromium Fixed Retainer, 3D-Printed Titanium Fixed Retainer
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Minia University