Clinical trials: Manipulation, Spinal
Healthy Subjects, Spinal Manipulation
Effects of the T12-L1 Vertebral Manipulation on Body Temperature, Arterial Tension and Cardiac Frequency
Single-blinded Randomized Controlled Trial conducted amongst a sample of healthy subjects divided into two different groups: the experimental treatment will consist in bilateral T12-L1 vertebral manipulation, whereas the control…
- Conditions
- Healthy Subjects, Spinal Manipulation, Manual Therapy
- Trial name
- NCT05315622
- Testing
- Bilateral vertebral manipulation of the T12-L1 vertebra through manual therapy
- Where
- Spain
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Spinal Manipulation, Chiropractic
Comparison of the Effectiveness of Chiropractic Manipulation Applied to the Lumbar Sacroiliac Region in Patients With Lumbar Disc Herniation
This study aims to compare the effectiveness of chiropractic manipulation applied to the lumbar and sacroiliac regions in patients with lumbar disc herniation.
- Conditions
- Spinal Manipulation, Chiropractic, Lumbal Disc Herniation
- Trial name
- CLuSH (NCT07037641)
- Testing
- Lumbar Spine Manipulation, Sacroiliac Joint Manipulation, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- SEFA HAKTAN HATIK
Cervicalgia
Validation of CPR for Manipulation for Neck Pain
The purpose of this study is to see if a recently developed clinical prediction rule (CPR) will successfully identify which patients with neck pain will respond rapidly and favorably to manipulation of their cervical spine.
- Trial name
- NCT02287337
- Testing
- Manipulation, Exercise
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Lower Back Pain
Using MRI Scans to Evaluate Spinal Manipulation
Lumbar spinal manipulation, or chiropractic adjusting, is thought to separate the surfaces of the spinal joints and thereby relieve lower back pain.
- Trial name
- NCT00070902
- Testing
- Lumbar side-posture spinal adjusting
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Low Back Pain
Patient Response to Spinal Manipulation
This is a biomechanical study which is Project 1 in the Developmental Center for Clinical and Translational Research in Chiropractic (DCRC I) (NIH/NCCAM grant 1 U19 AT004663-01; principal investigator Christine Goertz, DC, PhD).
- Trial name
- PRiSM (NCT01670292)
- Testing
- HVLA-SM
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Palmer College of Chiropractic
Low Back Pain
Effects of Spinal Manipulative Treatment on Inflammatory Markers in Low Back Pain Patients
It is expected that mechanical low back pain (LBP) is associated with inflammatory changes localized to the affected tissues. Could such changes be detected in cells involved in the inflammatory process in an in vitro model? The…
- Trial name
- NCT01766141
- Testing
- Spinal manipulation
- Where
- Canada
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Canadian Memorial Chiropractic College
Neck Pain
Linking Physiological Responses to Clinical Outcomes Following Cervical Spine Manipulation
The investigators aim to investigate the relationship between delivery kinetics, physiological responses and clinical outcomes following spinal manipulation.
- Trial name
- NCT06036849
- Testing
- Spinal manipulation, Spinal mobilization
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Spinal Manipulation
Effect of Spinal Manipulation on Experimental Pain in Asymptomatic Subjects.
Spinal manipulation is often used for its effect on pain, but more information is needed concerning its mechanisms of action.
- Trial name
- NCT03776708
- Testing
- Spinal manipulation
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institut Franco Europeen de Chiropratique
Low Back Pain
Effect of Two Osteopathic Techniques on Thickness of Paravertebral Muscles of the Lumbar Spine
The objective of this randomized controlled trial is to describe the effect of two osteopathic techniques - "high velocity, low amplitude" (HVLA) and muscle energy (ME) - on thickness, activation, strength, pressure pain…
- Trial name
- NCT01971983
- Testing
- High-velocity, low-amplitude (HVLA), Muscle energy (ME)
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Osteopathic Manipulative Treatment (OMT) Effects on Cerebrospinal Fluid (CSF) Dynamics
Exploring How Osteopathic Manipulative Treatment May Affect Spinal Fluid Flow: An MRI Study
his study aims to investigate whether Osteopathic Manipulative Treatment (OMT) affects cerebrospinal fluid (CSF) flow and glymphatic clearance in the human brain.
- Trial name
- NCT07629765
- Testing
- Osteopathic Manipulative Treatment (OMT)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Medical Education
Inertial Sensors Used to Learn Manipulation
Background Context: no studies have been identified to analyse the effect of real time feedback (using inertial sensors) on physiotherapy students learning the art of posterior-anterior thoracic manipulation (PATM).
- Trial name
- NCT01911338
- Testing
- Real Time Feedback, Traditional Learning Method
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Malaga
Pelvic Pain, Pelvic Pain Syndrome
Primary Dysmenorrhea and Osteopathic Treatment
This study is adressed to women with primary dysmenorrhea, it´s a gynecological disorder that is defined as colicky pain associated with menstruation and is located in the lower abdomen and in the lumbo-pelvic area.
- Conditions
- Pelvic Pain, Pelvic Pain Syndrome, Sexual Dysfunction
- Trial name
- NCT04910672
- Testing
- Control Group, Experimental Group
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Escuela de osteopatía de Madrid
Chronic Low-back Pain
The METRIC Study Protocol
The goal of this clinical trial is to test the effects of spinal manipulative therapy in individuals with chronic primary low back pain and determine the neurophysiological mechanisms underlying pain relief.
- Trial name
- METRIC (NCT05986370)
- Testing
- lumbar spinal manipulative therapy, full spine spinal manipulative therapy
- Where
- Canada
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Université du Québec à Trois-Rivières
Subluxation of Joint of Lumbar Spine
The Effects of Spinal Manipulation on Central Nervous System Activity Measured by Reflexive Calf Muscle Recruitment
This study investigated the effects of spinal manipulation on central nervous system activity. The presence of postactivation potentiation, an increase in muscular force production following prior muscular contractions, was…
- Trial name
- NCT02848456
- Testing
- Spinal Manipulation, Max Voluntary Isometric Contraction, SM+MVIC
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Grant Sanders
Manual Therapy
Manual Therapy Force Perception Scale
The objective of this observational study is to pilot a scale designed to assist clinicians in evaluating the force they perceive during manual therapy.
- Trial name
- NCT06430281
- Testing
- Manual therapy
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Université du Québec à Trois-Rivières
Neurophysiological Mechanisms Underlying Spinal Manipulation
The Effects of Mid-thoracic Manipulation on Heart Rate Variability.
The topic of spinal manipulation (SM) has been a source of increasing research over the past decade. Research has focused primarily upon the functional and clinical outcomes associated with SM.
- Trial name
- NCT02379871
- Testing
- Experimental Group
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mount St. Mary's College, Los Angeles, CA
Manipulation, Spinal
The Effect of a Single Spinal Manipulation on Cardiovascular Autonomic Activity
This study evaluates the effect of a single high-velocity low-amplitude spinal manipulation on both cardiovascular autonomic activity and pressure pain thresholds.
- Trial name
- NCT03273868
- Testing
- High velocity low amplitude manipulation
- Where
- France
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Institut Franco Europeen de Chiropratique
Motor Response Time
Influence of Spinal Manipulative Therapy Upon Stroop Task Performance
The purpose of this study is to determine if spinal manipulative therapy can affect cognitive processing as determined by performance on a Stroop task.
- Trial name
- NCT00335426
- Testing
- Spinal manipulative therapy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Logan College of Chiropractic
Asymptomatic Condition
The Immediate Effects of Spinal Manipulative Therapy on Kinetic and Kinematic Symmetry.
Athletes have been exposed to an ever increasing training load and subsequent biomechanical overload due to a constant demand for performance enhancement.
- Trial name
- NCT03361592
- Testing
- Spinal Manipulative Therapy
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Balance
Spinal Manipulative Therapy: Dual-Task Performance
The purposes of this study is to determined the effects of instrument applied spinal manipulative therapy upon dual-task performance involving complex postural and cognitive task.
- Trial name
- NCT00297934
- Testing
- Pro-adjuster mechanical spinal manipulative device
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Logan College of Chiropractic