Clinical trials: Manipulation
Chronic Low Back Pain
Visceral Manipulation in Patients With Chronic Low Back Pain
Non-specific chronic low back pain is a common multifactorial condition common to the world population. It is defined as a pain and discomfort located below the ribs and above the gluteal folds that may or may not have referred…
- Trial name
- NCT03101020
- Testing
- Active Visceral Manipulation, Standard care physiotherapy
- Where
- 2 sites in Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sorocaba
Low Back Pain
Spinal Manipulation Services vs. Prescription Drug Therapy for Long-term Care
Our overall objective is to assess the value of Spinal Manipulation Services as compared to Prescription Drug Therapy for long-term management of chronic Law back Pain (LBP).
- Trial name
- NCT03669354
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- Southern California University of Health Sciences
Hypertension
Chiropractic for Hypertension in Patients
The investigators propose a prospective randomized 2 arm parallel observer-blinded phase II clinical study comparing a distinct method of upper cervical chiropractic manipulation to a sham technique in 50 individuals with stage I…
- Trial name
- CHiP (NCT01020435)
- Testing
- Spinal Manipulation
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Palmer College of Chiropractic
Lumbar Spinal Stenosis
Study Comparing 3 Different Treatments for Arthritis of the Lower Back (Lumbar Spinal Stenosis)
BACKGROUND: Lumbar spinal stenosis - known by patients as "arthritis of the spine" - is a condition that is very common; found in about 30% of older adults.
- Trial name
- NCT01943435
- Testing
- NSAIDs; adjunctive analgesics; adjunctive anti-depressants, Lumbar epidural injection, Joint Mobilizations (spine, sacroiliac, hip)
- Where
- United States
- Volunteers
- 259 people
- Sponsor
- Michael Schneider, DC, PhD
Chronic Low Back Pain
Chiropractic Management of Chronic Lower Back Pain in Older Adults
The purpose of this study is to determine the effectiveness of Chiropractic management for treatment of chronic lower back pain in older adults.
- Trial name
- NCT00475787
- Testing
- Spinal Manipulation, Detuned Ultrasound
- Where
- 2 sites in United States
- Volunteers
- 136 people
- Sponsor
- US Department of Veterans Affairs
Healthy Males
HOP-3 Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone
The purpose of this investigational study is to determine how much male hormone, testosterone, is necessary to maintain sperm production in the testis.
- Trial name
- HOP-3 (NCT00839319)
- Testing
- Acyline, hCG (human chorionic gonadotropin), Testosterone gel
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Washington
Headache, Post-Concussion Syndrome
The Effectiveness of Osteopathic Manipulative Medicine in the Management of Headaches Associated With Post Concussion Syndrome
Pilot study looking at the Osteopathic Manipulative Treatment (OMT) for various headache types in patients with post-concussion syndrome (PCS).
- Trial name
- NCT04732338
- Testing
- Osteopathic Manipulative Therapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Hackensack Meridian Health
Acute Non-complicated Postural Neck Pain
The Effect of TheraBand® Kinesiology Tape on Post-manipulation Pain and Range of Motion
The purpose of this study is to determine if post-manipulation elastic therapeutic tape (ETT) with TheraBand® Kinesiology Tape to neck pain patients can impact neck range of motion (ROM) and post-manipulation pain.
- Trial name
- TBKTManip (NCT02691143)
- Testing
- TheraBand Kinesiology Tape
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Sport and Spine Rehab Clinical Research Foundation
Patient Safety, Manipulation, Spinal
(MIST1)-Part 1: Assessment & Feasibility of Post-Symptoms Evaluation
To increase patient safety culture in spinal manipulation therapy (SMT) this study will assess the ability to implement an active surveillance reporting system for a chiropractic teaching clinic and determining preliminary…
- Trial name
- MIST1 (NCT03412097)
- Testing
- active surveillance
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Parker University
Concussion Injury of Cerebrum, Cranial Osteopathic Medicine
Cranial Osteopathic Manipulative Medicine as an Adjunct Treatment for Concussion
Patients who have concussions exhibit an array of symptoms, also known as post-concussive symptoms, including headaches, feeling slowed down or foggy and difficulty with concentration.
- Trial name
- NCT03225599
- Testing
- Cranial Osteopathic Manipulative Medicine
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Low Back Pain
Predicting Patients' Response to Spinal Manipulation
The purpose of this study is to compare the clinical effectiveness of two types of chiropractic spinal manipulation to conservative medical care for patients at least 55 years old with sub-acute or chronic LBP.
- Trial name
- NCT00285649
- Testing
- HVLA-SM, LVVA-SM, Usual Medical Care
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Palmer College of Chiropractic
Airway Obstruction, Snoring
Anti-Snoring Appliances and Airway Manipulation in Patients Undergoing Anesthetic Sedation
Would patients using an anti-snoring appliance intraoperatively require less airway manipulation, interventions, and rescue maneuvers during anesthetic sedation cases compared to those who do not? The investigators will use…
- Conditions
- Airway Obstruction, Snoring, Sedation Complication
- Trial name
- NCT05748626
- Testing
- Anti-snoring device, No anti -snoring device during their procedure.
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Northwestern University
Low Back Pain
Effect of Spinal Manipulation on Sensorimotor Functions in Back Pain Patients
The long-term goal for this study is to understand the physiological mechanisms of various forms of spinal manipulation in order to refine and improve this therapy for appropriately selected patients.
- Trial name
- D2P3 (NCT00830596)
- Testing
- HVLA-SM, LVVA-SM
- Where
- United States
- Volunteers
- 221 people
- Sponsor
- Palmer College of Chiropractic
Prostate Cancer
Phase 2 Trial of Enzastaurin in Prostate Cancer in Participants Who Have Had Hormonal and Chemotherapy
The purpose is to see how quickly two different types of prostate cancer participants respond when taking enzastaurin. Cohort 1 - asymptomatic participants with androgen-independent prostate-specific antigen (PSA)-progressive…
- Trial name
- NCT00428714
- Testing
- enzastaurin
- Where
- 11 sites in United States
- Volunteers
- 73 people
- Sponsor
- Eli Lilly and Company
Dupuytren's Disease
Safety and Efficacy of Delayed Manipulation After Xiaflex Treatment in Subjects With Dupuytren's Contracture
The purpose of this study is to determine if of manipulation of digits following collagenase injection for treatment of Dupuytren's contracture is effected by the amount of time between injection and manipulation.
- Trial name
- NCT01226121
- Testing
- Clostridial collagenase injectable
- Where
- 2 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Indiana Hand to Shoulder Center
Prostate Cancer
Study of Chitosan for Pharmacologic Manipulation of AGE Levels in Prostate Cancer Patients
This study will examine the utility of chitosan for reduction of blood or tissue levels of AGEs in patients with prostate cancer who are clinically stable on androgen-deprivation therapy.
- Trial name
- NCT03712371
- Testing
- Chitosan
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Medical University of South Carolina
Capsule Endoscopy
The Second-Generation MCCG for Upper Gastrointestinal Tract.
The aim of this study is to evaluate the clinical application of the second-generation MCCG with higher image resolution and frame rate for upper gastrointestinal tract compared with the first-generation.
- Trial name
- NCT03977935
- Testing
- the second-generation MCCG
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Stroke
Talocrural Joint Manipulation in Stroke
The primary aim of the study is to investigate the effect of talocrural joint manipulation on the static balance of patients with stroke.
- Trial name
- NCT06523010
- Testing
- Talocrural Joint Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Bitlis Eren University
Physiological Measurements of Response and Reaction Times
Assessment of Chiropractic Treatment Using Reaction and Response Times in Members of the Special Operation Forces (ACT2)
This study is a randomized controlled trial designed to evaluate changes in reaction times (RTs) and response times (RespTs) following chiropractic treatment compared to controls in the Special Forces Qualified (SFQ) population…
- Trial name
- NCT02168153
- Testing
- Chiropractic Manipulative Therapy, Wait-list
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- RAND
Neck Pain
Spinal Pain and Autonomic Responses to Chiropractic Care
This randomized, single-blinded study will investigate the effects of Spinal Manipulative Therapy on Heart Rate Variability and Pain Sensitivity in a population of patients with recurrent and persistent neck pain.
- Trial name
- SPARC (NCT03576846)
- Testing
- Stretching and Spinal manipulative therapy, Stretching
- Where
- 2 sites in Sweden
- Volunteers
- 131 people
- Sponsor
- Karolinska Institutet