Clinical trials: Mask
Shortness of Breath
Impact of Facemasks on Running During COVID-19 Pandemic
Randomized crossover clinical trial in which a group of runners are ask to complete a 15 minutes standardized physical test on a treadmill.
- Trial name
- NCT04958863
- Testing
- Surgical mask, Polyester reusable mask
- Where
- Colombia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Fundacion Clinica Valle del Lili
Pandemic, COVID-19, Demodex Infestation
Could Wearing Face Mask Have Affected Demodex Parasite
This study aimed to examine whether wearing masks by healthy individuals during the Covid-19 pandemic created an environment for Demodex mites, by comparing it with the control group.
- Trial name
- NCT06185699
- Testing
- standard superficial skin biopsy (SSSB)
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Nurhan Döner Aktaş
Cataract
A Prospective, Randomized, Subject and Vision-assessor Masked, Multicenter Study Comparing Bilateral Clareon PanOptix, Bilateral Clareon PanOptix Pro, and Mixed Clareon PanOptix Pro/Vivity Intraocular Lens Implantation in Cataract Subjects
Prospective, randomized, multicenter, multi-arm, subject and vision-assessor-masked, two stage study with Stage 1 as a three-arm initial enrollment period, followed by Stage 2 as a head-to-head study refined based on the Stage 1…
- Trial name
- NCT06922084
- Testing
- Clareon PanOptix, Clareon PanOptix PRO, Mix-and-Match PanOptix/Vivity
- Where
- 2 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Berkeley Eye Center
Cataract, Presbyopia
Clinical Study to Evaluate the LensGen® Juvene® Intraocular Lens
To assess the safety and effectiveness of the Juvene® IOL for the treatment of aphakia and mitigation of the effects of presbyopia after removal of the natural crystalline lens due to cataract.
- Trial name
- Nirvana (NCT05364983)
- Testing
- Juvene IOL, Tecnis® Monofocal (ZCB00, PCB00 or DCB00)
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- LensGen, Inc.
Presbyopia Condition
A Randomized, Active-Controlled, Double-Masked, Crossover Study to Evaluate the Clinical Performance of Deseyne (Vifilcon C) Daily Disposable Soft Contact Lens for Presbyopia Extended Depth of Focus (EDOF)
The goal of this clinical trial is to learn if the contact lens we are testing will work to extend the range of clear focus at distance to provide an increase in clear vision at closer ranges without the additional need for…
- Trial name
- EDOF (NCT06698731)
- Testing
- Test lens, Control lens
- Where
- 3 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Bruno Vision Care
Blepharospasm, Blepharospasm, Benign Essential
Effect of Non-psychoactive Cannabidiol as an Adjunct to Botulinum Toxin in Blepharospasm
The planned study is a prospective analysis of non-psychoactive Cannabidiol (without THC) as an adjunctive therapy for blepharospasm in a masked double cross-over study.
- Conditions
- Blepharospasm, Blepharospasm, Benign Essential, CBD
- Trial name
- NCT04423341
- Testing
- Cannabidiol Oral Solution [Epidiolex]
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Silkiss Eye Surgery
Healthy
Variation In Facial Morphology As A Determinant Of Face Covering Performance: FACEFIT
This study examines the role of variations in the dimensions of facial features on the fitted filtering efficiency of face coverings available to the public during the COVID-19 pandemic.
- Trial name
- FACEFIT (NCT05388201)
- Testing
- N95, KN95, KF94
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Anesthesia
Different Dose of Esketamine Inhibiting Response to Laryngeal Mask Airway Insertion
Objective To prospectively determine the median effective dose (ED50) of propofol for inhibiting a response to laryngeal mask airway (LMA) insertion when combined with different doses of esketamine in female patients.
- Trial name
- NCT06370130
- Testing
- Esketamine 0.2mg/kg, Esketamine 0.3mg/kg
- Where
- China
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Aerospace Center Hospital
Dry Eye Disease
Eye Mask on Sleep Quality and Tear Layer Function in Patients With Dry Eye Disease
This randomized clinical trial (RCT) was aimed to determine the effects of eye masking on sleep quality and tear layer function in patients with dry eye disease.
- Trial name
- NCT06016166
- Testing
- Eye mask
- Where
- Iran
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hamideh Sabbaghi
Emergency Airway Management, Gastric Inflation Risk During Bag-Valve-Mask Ventilation
The Airway Pressures During Bag-Valve-Mask Ventilation
Background and Objective Bag-valve-mask (BVM) ventilation is commonly used in emergency airway management, but the positive pressure generated may increase aspiration risk.
- Conditions
- Emergency Airway Management, Gastric Inflation Risk During Bag-Valve-Mask Ventilation, Breathing Emergency
- Trial name
- NCT07591909
- Testing
- Two Handed CE Technique, Two Handed TE Technique, One Handed Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Akdeniz University Hospital
Ejaculation Delayed
A Clinical Investigation to Assess the Effectiveness of Benzocaine Condoms in Healthy Adult Men
This investigation is designed to evaluate the effectiveness of two NRL condoms with Benzocaine paste compared with a standard NRL control.
- Trial name
- NCT05255770
- Testing
- Test condom A (NRL condom with 5% benzocaine paste), Test condom B (NRL condom with 3% benzocaine paste), Control NRL condom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Sedentary Lifestyle
Effectiveness of Adding Voluntary Pelvic Floor Muscle Contraction to a Pilates Exercises Program
Adding voluntary pelvic floor muscle contraction to a Pilates exercises program can improve the pelvic floor muscle strength on sedentary nulliparous women.
- Trial name
- NCT02748473
- Testing
- Pilates Exercises program, Pelvic floor muscle strength, 3D perineal ultrasound
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Dentine Hypersensitivity
Single Application of Desensitizing Pastes as Dentin Sensitivity Treatment
The aim of this study was to evaluate the efficacy of three desensitizing toothpastes for immediate and intermediate-term relief of CDH, when compared with a control toothpaste.
- Trial name
- NCT02018783
- Testing
- Colgate, Sensodyne, Nano P
- Where
- Brazil
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Refractive Surgery
CONTOURA vs WFO Ablation PRK & LASIK
This is a prospective randomized contralateral double-masked study. Each patient will be randomized as to which eye undergoes wave-front optimized (WFO) vs.
- Trial name
- NCT05037370
- Testing
- Wave-Front Optimized (WFO) ablation vs Topography-guided (TG) ablation
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- 59th Medical Wing
COVID-19
Reduction in COVID-19 Infection Using Surgical Facial Masks Outside the Healthcare System
In the current COVID-19 pandemic with coronavirus, SARS-COV2, the Danish Health Authorities recommend using facial masks in the health care system when handling patients presumed or proven to be infected with the virus.
- Trial name
- NCT04337541
- Testing
- Surgical facial mask
- Where
- Denmark
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Educational Problems
Intubation and Ventilation Skill Training Using Modified Peyton's Four-Step Approach
Endotracheal intubation and mask ventilation procedural skills are basic skills which have to be learnt by medical student and have to be practiced directly.
- Trial name
- NCT05511142
- Testing
- Classic Peyton's Four-Step Approach, Modified Peyton's Four-Step Approach
- Where
- Indonesia
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Eye Diseases
A Study of Laquinimod Eye-drops in Healthy Participants
This is a Phase 1 randomized, double-masked, placebo-controlled study performed with healthy participants to assess the safety and tolerability of laquinimod eye-drops.
- Trial name
- NCT05187403
- Testing
- Laquinimod
- Where
- Austria
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Active Biotech AB
Respiratory Tract Infections
Pediatric Mask Fit Study
This study will evaluate the performance of various face masks and respirators on children by examining their fitted filtration efficiency (FFE) and mask fit.
- Trial name
- NCT05942534
- Where
- Canada
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Covid19
COVID-19: The Effectiveness of Free Face Mask Distribution
The investigators will carry out a randomised trial of free face mask distribution in Stovner District, Oslo, Norway. Ten grocery stores will serve as study sites.
- Trial name
- NCT04866589
- Testing
- Distribution of free face masks
- Where
- Norway
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Norwegian Institute of Public Health
Anesthesia, Local
A Study of the Safety and Anesthetic Effect of AG-920 Topical Ophthalmic Solution
This is a Phase 3, randomized, placebo-controlled, double masked, parallel design study in healthy subjects performed in the US.
- Trial name
- NCT04829344
- Testing
- AG-920
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- American Genomics, LLC