Clinical trials: Mask
Obese
The Effect of Mask Combined With High Flow Oxygen on Preoxygenation During Induction of General Anesthesia in Obese Patients
There is a risk of airway-related incidents during anaesthesia associated with obesity. High-flow nasal oxygen is advocated for perioperative preoxygenation in obese patients to reduce airway adverse reactions.
- Trial name
- NCT06562660
- Testing
- apnoeic
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Henan Provincial People's Hospital
Allergic Conjunctivitis
Study Evaluating the Safety of KetoNaph Ophthalmic Solution in Healthy Volunteers
This study is being conducted to evaluate the safety of KetoNaph ophthalmic solution in healthy adult subjects and in pediatric subjects with a history or family history of ocular allergy.
- Trial name
- NCT01159015
- Testing
- KetoNaph, Vehicle
- Volunteers
- 534 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Healthy
Study to Evaluate Safety, Tolerability and Pharmacokinetics of rhNGF Eye Drops in Healthy Volunteers
The primary objective of this study is to assess the safety and tolerability of single and multiple ascending doses of rhNGF when administered as eye drops in healthy subjects.
- Trial name
- NGF0112 (NCT01744704)
- Testing
- rhNGF 0.5 µg/mL Sentinel, rhNGF 5 µg/mL Sentinel, rhNGF 20 µg/mL Sentinel
- Where
- 2 sites in Switzerland, United Kingdom
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Dompé Farmaceutici S.p.A
General Anaesthesia
Comparing Between Air-Q Intubating Laryngeal Airway and Ambu® AuraGain™
The aim of this randomized study is conducted is to evaluate the performance and safety of air-Q intubating laryngeal airway as primary airway device in various short surgical procedure in children compared to Ambu® AuraGain™…
- Trial name
- Nira (NCT03130413)
- Testing
- Ambu Aura Gain supraglottic airway, Air-Q supraglottic airway
- Where
- Malaysia
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Health Behavior
Evaluating the Impact of Vocal Health Education on Mask-wearing Workers During COVID-19
The purpose of this clinical trial is to understand how viewing educational health modules impacts vocal health behaviors in mask-wearing healthcare workers.
- Trial name
- NCT04858542
- Testing
- Educational Vocal Health Modules
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Herpes Simplex
30-Day Trial of Oral Valtrex or Valtrex Plus Aspirin on Shedding of HSV DNA in Tears and Saliva of Volunteers
The purpose of this study is to determine whether oral Valtrex alone or in combination with aspirin will reduce the shedding of herpes simplex virus DNA in the tears and saliva from volunteers with no evidence of ocular herpes…
- Trial name
- NCT00587496
- Testing
- valacyclovir hydrochloride, valacyclovir plus aspirin
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Eye Institute (NEI)
Mask Usage Condition
Acute Mask Effects on Walk Distance and Vital Signs
The goal of this prospective observational study is to investigate the acute effects of mask use on walking distance and vital signs in healthy individuals aged 18-24 years.
- Trial name
- NCT06634238
- Testing
- Incremental shuttle walk test
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nagihan Acet
Ocular Redness
Study Evaluating the Safety and Efficacy of Brimonidine Tartrate Ophthalmic Solution in Adult and Geriatric Subjects
The purpose of this study is to evaluate the safety and efficacy of brimonidine tartrate 0.025% ophthalmic solution used four times daily in a population of adult and geriatric subjects
- Trial name
- NCT01675609
- Testing
- Brimonidine tartrate 0.025%
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Eye Therapies, LLC
Snorkeling, Face Mask Squeeze
Evaluation of Full Face Snorkel Masks (FFSMs)
Recently, multiple models of Full Face Snorkel Mask (FFSM) have entered the retail market. However, several fatalities have been reported to the non-profit agency Divers Alert Network (DAN) for snorkelers who were using FFSMs…
- Conditions
- Snorkeling, Face Mask Squeeze, Underwater Physiology, Swimming Physiology
- Trial name
- NCT04783688
- Testing
- Full Face Snorkel Mask (FFSM)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Duke University
Inspired Oxygen (FIO2), End-tidal Oxygen (ETO2), End-tidal Carbon Dioxide (ETCO2) and Respiratory Rate (RR) Will be Measured Every 30 Seconds
Comparison of the Classic Face Mask Versus NuMask for Preoxygenation
Currently used face mask has certain disadvantages; such as, not providing a complete seal in certain patients, causing hand fatigue after holding the mask in place for more than a few minutes, causing claustrophobia in an…
- Trial name
- NCT01865851
- Testing
- Classic Face Mask and NuMask
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nimmagadda, Usharani, M.D.
Anesthesia
Effects of Low Dose Neuromuscular Blocker Usage on Laryngeal Mask Application
Cystoscopy is a simple, effective and reliable method in current urological practice. Anesthesia may be required in cystoscopy for therapeutic purpose, however it may not be necessary for diagnostic cystoscopy.
- Trial name
- NCT03424356
- Testing
- Rocuronium Bromide, Saline Solution, Fentanyl
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Postmenopausal Osteoporosis
Phase 1 Study to Compare CMAB807 Injection to Prolia® in Healthy Volunteers
CMAB807 is a human monoclonal antibody targeting the key bone resorption mediator RANKL. The drug is administered via subcutaneous injection once six months and is approved for various indications, including the treatment of…
- Trial name
- NCT03925051
- Testing
- Prolia®, CMAB807
- Where
- China
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Shanghai Biomabs Pharmaceutical Co., Ltd.
Sleep Staging
Nyx3 Data Collection Study
Each participant will wear the Nyx3 eye mask and Hypnodyne headband for 1 night at-home. Objectives include collecting and evaluating data quality from the Nyx3 eye mask, and exploring the impact of its paced breathing feature on…
- Trial name
- NCT07099183
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ResMed
Respiratory Failure
Bag Valve Mask vs Non-rebreather at Flush Rate
Healthy volunteers will participate in a crossover trial comparing preoxygenation with a non-rebreather mask to a bag-valve mask (with and without a simulated mask leak) at the flush rate of oxygen (fully opening standard oxygen…
- Trial name
- NCT02798302
- Testing
- Flush rate oxygen using a standard flowmeter (Precision Medical, 8MFA). See description for details. This is specific.
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hennepin Healthcare Research Institute
Face-masks, Exercise
Protective Face Masks and Cardiopulmonary Parameters at Rest and During Exercise in Children
This study will examine the possible effects of protective surgical masks on the cardiorespiratory function of children aged 8-14 years at rest and during exercise. The study will consist of two phases: Phase I: No face mask. 1.
- Trial name
- NCT05193422
- Testing
- Spirometry - baseline, Spirometry - post CPET, Nasal peak inspiratory flow - baseline
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Patras
Precedex Effect to Propofol Requirement
The Effect of Dexmedetomidine on Propofol Requirement for Insertion of Laryngeal Mask Airway
Propofol frequently used as an inducting medication for insertion Laryngeal mask airway(LMA). But propofol alone can be not sufficient for inhibiting upper airway reflex and also result in cardiovascular suppression under enough…
- Trial name
- NCT02284672
- Testing
- Dexmedetomidine, Normal saline
- Where
- South Korea
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Ajou University School of Medicine
Obese
Ambu®AuraGain™ Versus I-gel® in Obese Patients
The aim of this study is the randomized comparison of two laryngeal mask (Intersurgical i-gel® and Ambu®AuraGain™) in obese patients
- Trial name
- NCT03110393
- Testing
- Ambu AuraGain, Intersurgical i-gel
- Where
- Switzerland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Schulthess Klinik
Subcutaneous Abdominal Adiposity
An Evaluation of the Safety and Efficacy of LIPO-102 for the Reduction of Subcutaneous Abdominal Adiposity
This is a double-masked evaluation of the safety and efficacy of LIPO-102 for the reduction of subcutaneous abdominal adiposity.
- Trial name
- NCT01096979
- Testing
- LIPO-102
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Neothetics, Inc
Airway Management
A Comparison of Supraglottic Airway Devices
This study aimed to compare the advantages and disadvantages of LMA Supreme, LMA Classic and LMA Fastrach regarding ease of insertion, repositioning, insertion time, effects on hemodynamic parameters, provision of adequate and…
- Trial name
- NCT02339519
- Testing
- LMA CLASSIC, LMA FASTRACH, LMA SUPREME
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Healthy
Safety and Tolerability of ACU-4429
The purpose of this study is to evaluate the safety and tolerability of a new investigational drug (ACU-4429) in healthy human volunteers.
- Trial name
- NCT00703183
- Testing
- ACU-4429
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Kubota Vision Inc.