Clinical trials: Mask
Focus is on Healthy Subjects
Reusable, Transparent, and Reconfigurable N95-equivalent Respirator Masks: Design, Fabrication, and Trials for Enhanced Adoption
The goal of this observational usability study was to evaluate the comfort, breathability, fit, communication, and user acceptance of the SEEUS95 transparent reusable respirator in healthy adult volunteers.
- Trial name
- NCT07711145
- Testing
- Reusable, Transparent, and Reconfigurable N95-Equivalent Respirator Masks: Design, Fabrication, and Clinical Trials for Enhanced Adoption
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- SEEUS95 Inc
Laryngeal Mask Airway
Three Inflation Methods of Ambú Auragain™ and Its Adverse Effects
Laryngeal mask is a common supraglottic device (SGD) used in the daily practice for airway management. Consecutive generations have permitted an expansion of its use.
- Trial name
- NCT04795544
- Testing
- Intracuff pressure measurement
- Where
- Spain
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Chronic Allergic Conjunctivitis
OTX-14-001: A Phase 2 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Chronic Allergic Conjunctivitis
The objective of the study was to evaluate the efficacy and safety of OTX-DP (dexamethasone insert) 0.4 mg for intracanalicular use when placed in the canaliculus of the eyelid for the treatment of the signs and symptoms of…
- Trial name
- NCT02062905
- Testing
- Dexamethasone
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ocular Therapeutix, Inc.
Airway Devices
Laryngeal Mask Airway Versus Air Q Laryngeal Airway
Nowadays, supraglottic airway devices are simple and effective alternatives to endotracheal intubation. Both laryngeal mask airway LMA and air-Q airway are supraglottic airway devices that can be used to maintain and protect…
- Trial name
- NCT04021407
- Testing
- LMA group, AirQ group
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Macular Degeneration, Diabetic Retinopathy
A Phase 1 Safety Study of TG100801 Eye Drops in Healthy Volunteers
The formation of new blood vessels (angiogenesis), blood vessel leakage, and inflammation contribute to the progression of the eye disease, age-related macular degeneration (AMD), which is the leading cause of irreversible…
- Trial name
- NCT00414999
- Testing
- TG100801
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- TargeGen
Glaucoma
Comparison Between an Electronic Mobile Device and Optical Coherence Tomography to Determine Cup-to-disc Ratio
This study was a non-inferiority trial with masked data analysis. Individuals ranging from 18 to 60 years from both genders that met the pre-defined criteria were included.
- Trial name
- NCT02988752
- Testing
- Electronic Mobile Device, Optical Coherence Tomography
- Where
- Brazil
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Clinica Oftamologica Zona Sul
Preterm Birth
Use of CO2 Detectors to Help Provide Effective Breaths During Resuscitation of Preterm Newborns
Effective ventilation is the single most vital intervention to improve outcome of resuscitation in the neonatal population. Assessments of effective ventilations are based on clinical parameters, but may be difficult due to…
- Trial name
- NCT04287907
- Testing
- Monitor Group
- Where
- Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Nitrous Oxide Inhalation Sedation
Comparison of the Silhouette and Porter Brown Systems Used in Inhalation Sedation
This is a randomised non-blinded controlled clinical trial, which involves the measurement of efficiency and acceptability of the Silhouette Mask system and compares it with the Porter Brown Mask system used for Inhalation…
- Trial name
- NCT04734509
- Testing
- Silhouette breathing system
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Sleep Disordered Breathing (SDB), Sleep Apnea
Detection of Sleep Stages and Arousals Using Neural Network Classifiers
The objective of this clinical study is to evaluate the accuracy of the Smart Mask V1 System (herein 'Smart Mask') in measuring sleep stages-Stage N1/N2, Stage N3, Rapid Eye Movement (herein 'REM'), and WAKE-arousals, and the…
- Trial name
- SSAM (NCT07136272)
- Testing
- SSAM, Polysomnography, EnsoSleep
- Where
- 3 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Pathway Medtech, LLC.
Sleep-disordered Breathing (SDB), Sleep Apnea
Validation of the Smart Mask V1 System and Its Measurements of SpO2 and Pulse Rate
The goal of this clinical study is to investigate a new medical device, the Smart Mask V1 System (herein 'Smart Mask'), and particularly its measurements of blood oxygen levels (SpO2) and pulse rate (PR) in healthy adults aged 18…
- Conditions
- Sleep-disordered Breathing (SDB), Sleep Apnea, Sleep Quality
- Trial name
- SMV1: PPG (NCT07086742)
- Testing
- Smart Mask V1 System
- Where
- Belgium
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Pathway Medtech, LLC.
Glaucoma, Ocular Hypertension
A Single Centre Study to Evaluate 3 Ophthalmic Formulations in Healthy Subjects
A Single Centre, Placebo-Controlled, Double-Masked, Sequential Designed Study to Evaluate 3 Ophthalmic Formulations of AMA0076 in Healthy Subjects
- Conditions
- Glaucoma, Ocular Hypertension, Eye Disease
- Trial name
- NCT02003547
- Testing
- AMA0076
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Amakem, NV
Laryngeal Masks
Supraorbital Pressure Versus Jaw Thrust for Assessing the Adequate Depth of Anesthesia for LMA Insertion in Children
BACKGROUND AND OBJECTIVES The purpose of this study is to assess whether the loss of motor response to supraorbital pressure can be an alternative to that of jaw thrust to predict optimal condition for laryngeal mask airway (LMA)…
- Trial name
- NCT02618525
- Testing
- Supraorbital pressure, Jaw thrust maneuver
- Where
- Nepal
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Presbyopia, Near Vision
Phase 3 Safety Study of LNZ100 and LNZ101 for the Treatment of Presbyopia Subjects
Safety Study of the Long-Term Safety of LNZ100 \& LNZ101 in Presbyopic Subjects
- Conditions
- Presbyopia, Near Vision, Refractive Error, Eye Diseases
- Trial name
- NCT05753189
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle
- Where
- 40 sites in United States
- Volunteers
- 362 people, healthy volunteers welcome
- Sponsor
- LENZ Therapeutics, Inc
Value of Continuous Pressure Monitoring in Laryngeal Mask
Continuous Laryngeal Cuff Pressure Monitoring
The aim of this study is to evaluate the airway seal of LMA during intraoperative manipulation.
- Trial name
- NCT03654924
- Testing
- Laryngeal Mask
- Where
- Singapore
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Airway
Evaluation of the Ambu® AuraGain in Ambulatory Surgery
The study was designed to evaluate the success rate, time of insertion, sealing efficacy and security of the Ambu® AuraGain in patients undergoing ambulatory surgery by one anesthetist
- Trial name
- NCT04501068
- Testing
- Ambu® AuraGainTM
- Where
- 2 sites in Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hospital General Universitario Gregorio Marañon
Healthy Volunteers
Impact of Different Face Masks on Maximal and Submaximal Performance Testing During COVID-19
In COVID 19, masks wearability has become a new normal and this "new normal" presented evidence-based performance limitations. The study findings are aimed to objectify parametric changes (if any) and therefore, will assist in…
- Trial name
- NCT05150613
- Testing
- No Mask, Surgical Mask, N95 Mask
- Where
- 2 sites in Pakistan
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Hypoxemia
The Effects of Wearing a Face Mask During Exercise in Youth Hockey Players During COVID-19
There is concern that wearing a face mask during COVID will affect oxygen uptake, especially during intense exercise. COVID transmission is especially prevalent in sports such as hockey, where there is close contact between…
- Trial name
- NCT04874766
- Testing
- Wingate exercise test and on-ice testing while wearing a face mask
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Influenza Infection
Catechin Containing Mask for the Prevention of Influenza Infection
The purpose of this study is to evaluate the effects of catechin extracts containing mask on prevention of influenza infection.
- Trial name
- NCT00812448
- Testing
- tea catechin extracts
- Where
- 2 sites in Japan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Shizuoka
Skin Condition, Skin Hydration
Efficacy Test of a Moisturizing and Anti-aging Facial Mask
The objective of this study is to evaluate the effect of Moisturizing facial mask and Anti-aging facial mask on human skin condition improvement.
- Conditions
- Skin Condition, Skin Hydration, Anti Skin Aging
- Trial name
- NCT07622160
- Testing
- Hydrating Repairing Mask, Anti-aging Rejuvenating Mask
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- TCI Co., Ltd.
Macular Degeneration
A Safety Study to Evaluate Pazopanib Eye Drops in Healthy Volunteers
A study to determine the safety and tolerability of pazopanib eye drops. The study will also determine how the drug is absorbed and metabolized over time.
- Trial name
- NCT01072214
- Testing
- pazopanib
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline