Clinical trials: Mask
Adenoviral Conjunctivitis
Treatment of Adenoviral Conjunctivitis With SHP640 Compared to Povidone-iodine (PVP-I) and Placebo
The purpose of this study is to determine if an investigational treatment is effective compared with placebo and PVP-Iodine in the treatment of adults and children with adenoviral conjunctivitis.
- Trial name
- NCT02998541
- Testing
- SHP640, PVP-I 0.6%
- Where
- 130 sites in United States, Australia and 14 more
- Volunteers
- 219 people
- Sponsor
- Shire
Chronic Allergic Conjunctivitis
OTX-14-001: A Phase 2 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Chronic Allergic Conjunctivitis
The objective of the study was to evaluate the efficacy and safety of OTX-DP (dexamethasone insert) 0.4 mg for intracanalicular use when placed in the canaliculus of the eyelid for the treatment of the signs and symptoms of…
- Trial name
- NCT02062905
- Testing
- Dexamethasone
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ocular Therapeutix, Inc.
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer
This phase II trial compares the effectiveness of adding BMX-001 to usual symptom management versus usual symptom management alone for reducing oral mucositis in patients who are receiving chemoradiation for head and neck cancer.
- Conditions
- Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Head and Neck Squamous Cell Carcinoma
- Trial name
- NCT06532279
- Testing
- Best Practice, Biospecimen Collection, Cisplatin
- Where
- 153 sites in United States
- Volunteers
- 98 people
- Sponsor
- NRG Oncology
Geographic Atrophy Secondary to Age-related Macular Degeneration
Phase 2 Study of ADX-038 in Participants With Geographic Atrophy
Phase 2 study is designed to assess the efficacy of ADX-038 compared with placebo in participants with GA secondary to AMD. Safety, pharmacokinetics (PK), and pharmacodynamics (PD) will also be assessed.
- Trial name
- NCT06990269
- Testing
- ADX-038
- Where
- 83 sites in United States, Australia and 10 more
- Volunteers
- 240 people
- Sponsor
- ADARx Pharmaceuticals, Inc.
General Anesthesia With Endotracheal Intubation in Surgery
Cohort 2 Efficacy of Nasopharyngeal Ventilation With Endotracheal Tube for Surgery
Failed mask ventilation poses an increased risk of de-oxygenation to the patient undergoing general anesthesia. Nasopharyngeal ventilation may be a valid alternative for mask ventilation allowing for better oxygenation during the…
- Trial name
- MASK (NCT02018146)
- Testing
- Mask then nasopharyngeal, Nasopharyngeal then mask
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Louisville
Adenoviral Conjunctivitis
Treatment of Adenoviral Conjunctivitis With SHP640 Compared to Placebo
The purpose of this study is to determine if an investigational treatment is effective compared with placebo in the treatment of adults and children with adenoviral conjunctivitis.
- Trial name
- NCT02998554
- Testing
- SHP640
- Where
- 31 sites in United States, Puerto Rico
- Volunteers
- 156 people
- Sponsor
- Shire
Geographic Atrophy
A Study Investigating the Efficacy and Safety of Intravitreal Injections of ANX007 in Patients With Geographic Atrophy
This study is being conducted in participants with geographic atrophy (GA) secondary to age-related macular degeneration (AMD) to determine if intravitreal (IVT) injections of ANX007 reduce GA lesion growth rate.
- Trial name
- ARCHER (NCT04656561)
- Testing
- ANX007
- Where
- 53 sites in United States, Australia and 1 more
- Volunteers
- 270 people
- Sponsor
- Annexon, Inc.
Acute Viral Conjunctivitis
FST-100 in the Treatment of Acute Viral Conjunctivitis
This randomized, double masked, multi-center study is being conducted to support the safety and efficacy of FST-100 for the treatment of acute viral conjunctivitis.
- Trial name
- NCT01461954
- Testing
- FST-100, FST-100 Vehicle
- Where
- 2 sites in United States, Brazil
- Volunteers
- 132 people
- Sponsor
- Shire
Dry Eye
Phase 2b Controlled Study of Dosing Techniques - Part B
Double-masked, dose-response of two concentrations of IVW-1001
- Trial name
- NCT07161011
- Testing
- IVW-1001 Ophthalmic Eyelid Wipe 0.2%, IVW-1001 Ophthalmic Eyelid Wipe 0.4%
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- IVIEW Therapeutics Inc.
Airway Devices
Laryngeal Mask Airway Versus Air Q Laryngeal Airway
Nowadays, supraglottic airway devices are simple and effective alternatives to endotracheal intubation. Both laryngeal mask airway LMA and air-Q airway are supraglottic airway devices that can be used to maintain and protect…
- Trial name
- NCT04021407
- Testing
- LMA group, AirQ group
- Where
- Egypt
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Glaucoma, Open-Angle, Ocular Hypertension
A 12-Week, Randomized, Double-Masked, Parallel Group Comparison Of Evening Dosing With Xalacom In Subjects With Glaucoma
To demonstrate statistical superiority of the combination of latanoprost and timolol to the individual therapy of latanoprost and timolol based on intraocular pressure measurements at 8 AM, 10 AM, 4 PM at weeks 2, 6 and 12.
- Trial name
- NCT00159653
- Testing
- Xalacom, Xalatan, Timolol
- Where
- 55 sites in United States, Canada
- Volunteers
- 500 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Difficult Mask Ventilation, Difficult Intubation
Effectiveness of C-MAC Video-stylet Versus C-MAC D- Blade Video-laryngoscope for Tracheal Intubation
Videolaryngoscopy provides a better laryngeal view and do not need airway alignment for tracheal intubation.
- Trial name
- NCT04759300
- Testing
- C-MAC VS, C-MAC VL D -blade
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Alexandria University
Macular Degeneration, Diabetic Retinopathy
A Phase 1 Safety Study of TG100801 Eye Drops in Healthy Volunteers
The formation of new blood vessels (angiogenesis), blood vessel leakage, and inflammation contribute to the progression of the eye disease, age-related macular degeneration (AMD), which is the leading cause of irreversible…
- Trial name
- NCT00414999
- Testing
- TG100801
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- TargeGen
Branch Retinal Vein Occlusion, Macular Edema
Conbercept Ophthalmic Injection for Patients With Macular Edema Caused by Branch Retinal Vein Occlusion
The purpose of this study is to verify the efficacy and safety of intravitreal injection of conbercept in patients with macular edema (ME) caused by branch retinal vein occlusion (BRVO).
- Trial name
- BRAVE (NCT03108352)
- Testing
- Conbercept ophthalmic injection
- Where
- 31 sites in China
- Volunteers
- 255 people
- Sponsor
- Chengdu Kanghong Biotech Co., Ltd.
Postoperative Ocular Inflammation, Postoperative Ocular Pain
A Phase 3 Study Evaluating the Safety and Efficacy of TRIESENCE® (Injectable Suspension) for the Treatment of Ocular Inflammation and Pain After Ophthalmic Surgery
This study is designed to evaluate the safety and efficacy of TRIESENCE® (triamcinolone acetonide injectable suspension) in patients undergoing ophthalmic procedures.
- Trial name
- NCT07832552
- Testing
- TRIESENCE (triamcinolone acetonide injectable suspension)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Harrow Inc
Post Operative Pulmonary Complications
HFNC Versus Oxygen Face Mask on Postoperative Pulmonery Complications
Eighty adult patients were randomly categorized into two equal groups (forty patients each): HFNC was applied to group I, and a simple oxygen face mask was applied to group II.
- Trial name
- NCT05548309
- Testing
- HFNC, Oxygen face mask
- Where
- Egypt
- Volunteers
- 94 people
- Sponsor
- Alexandria University
Glaucoma
Comparison Between an Electronic Mobile Device and Optical Coherence Tomography to Determine Cup-to-disc Ratio
This study was a non-inferiority trial with masked data analysis. Individuals ranging from 18 to 60 years from both genders that met the pre-defined criteria were included.
- Trial name
- NCT02988752
- Testing
- Electronic Mobile Device, Optical Coherence Tomography
- Where
- Brazil
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Clinica Oftamologica Zona Sul
Preterm Birth
Use of CO2 Detectors to Help Provide Effective Breaths During Resuscitation of Preterm Newborns
Effective ventilation is the single most vital intervention to improve outcome of resuscitation in the neonatal population. Assessments of effective ventilations are based on clinical parameters, but may be difficult due to…
- Trial name
- NCT04287907
- Testing
- Monitor Group
- Where
- Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Nitrous Oxide Inhalation Sedation
Comparison of the Silhouette and Porter Brown Systems Used in Inhalation Sedation
This is a randomised non-blinded controlled clinical trial, which involves the measurement of efficiency and acceptability of the Silhouette Mask system and compares it with the Porter Brown Mask system used for Inhalation…
- Trial name
- NCT04734509
- Testing
- Silhouette breathing system
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Cataract
A Comparison of Visual Function After Bilateral Implantation of Presbyopia Correcting Intraocular Lenses
To prospectively evaluate postoperative visual and refractive parameters in a series of subjects bilaterally implanted with AcrySof ReSTOR +3 vs. those bilaterally implanted with LENTIS MPlus Intraocular Lens (IOL).
- Trial name
- NCT01299155
- Testing
- ReSTOR +3, LENTIS MPlus
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- Alcon Research
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