Clinical trials: Mastalgia
Fibrocystic Breast Condition (FBC)
A Randomized Double-blind, Placebo Controlled, Multi-center Study to Evaluate the Safety, Tolerability and Potential Effects of the Dietary Supplement Violet™ Molecular Iodine (I2) on Breast Health in Women With Cyclic Breast Discomfort and Tenderness
This is a randomized, double-blind, placebo controlled, multi-center study to evaluate the safety, tolerability and potential effects of dietary supplement Violet™ Iodine on breast health in women with cyclic breast discomfort…
- Trial name
- NCT02676336
- Testing
- Violet™ Molecular Iodine (I2)
- Where
- 2 sites in United States, Canada
- Volunteers
- 31 people
- Sponsor
- BioPharmX, Inc.
Breast Neoplasms
The Use of Pentoxifylline and Vitamin E in the Treatment of Chronic Breast Pain
An estimated 20 - 45 % of women treated with breast conserving treatment experience chronic pain in the treated breast. The aetiology of this is poorly understood. Some of these women have signs of chronic radiation mastitis.
- Trial name
- NCT00188669
- Testing
- pentoxifylline, alpha-Tocopherol
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University Health Network, Toronto
Pain Syndrome, Pain, Postoperative
The Impact of Pecs Blocks on Postmastectomy Pain Syndrome
The aim of the present study is to investigate the incidence of chronic pain following breast cancer surgery in Cyprus, discover its associated risk factors and explore the impact of Pecs Blocks on the appearance of post…
- Conditions
- Pain Syndrome, Pain, Postoperative, Chronic Pain, Breast Cancer
- Trial name
- NCT04586751
- Testing
- Pecs block, no Pecs block
- Where
- 3 sites in Cyprus, Greece
- Volunteers
- 64 people
- Sponsor
- Aretaieion University Hospital
Bone Pain in Stage I - III Breast Cancer
NOLAN: Naproxen or Loratadine and Neulasta
The primary objective of the study is to estimate the difference in bone pain between breast cancer patients receiving chemotherapy and pegfilgrastim and either no prophylactic intervention, prophylactic naproxen, or prophylactic…
- Trial name
- NOLAN (NCT01712009)
- Testing
- Naproxen, Loratadine, Pegfilgrastim
- Where
- 83 sites in United States
- Volunteers
- 600 people
- Sponsor
- Amgen
Postoperative Pain, Postsurgical Pain
Comparison of the Postoperative Analgesic Efficacy of SAP and SPSIP Blocks in Patients Undergoing Mammoplasty
The aim is to compare the postoperative analgesic efficacy of serratus anterior plane block (SAPB) and serratus posterior superior intercostal plane block (SPSIPB) in patients undergoing mammoplasty surgery.
- Conditions
- Postoperative Pain, Postsurgical Pain, Breast Pain
- Trial name
- SPSIP (NCT07302399)
- Testing
- Serratus Anterior Plane Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Benign Breast Disease, Fibrocystic Disease of Breast
Effects of Tamoxifen in Premenopausal Women With Benign Breast Disease Not at High-Risk of Developing Breast Cancer
The purpose of the study is to determine the efficacy and relapse rate of low dose, short duration treatment with tamoxifen in benign breast disease amenable to hormonal therapy with respect to etiology and estrogen receptor…
- Conditions
- Benign Breast Disease, Fibrocystic Disease of Breast, Fibroadenoma, Mastalgia
- Trial name
- NCT00999921
- Testing
- Tamoxifen, Evening Primrose Oil
- Where
- India
- Volunteers
- 256 people
- Sponsor
- Medical College and Hospital Kolkata
Breast Pain
Acupuncture for Non-cyclical Breast Pain
Breast pain or mastalgia is a common and troublesome symptom for many women. Whereas cyclical breast pain related to hormonal fluctuations can frequently be treated, non-cyclical breast pain can go untreated due to its various…
- Trial name
- NCT00275574
- Testing
- acupuncture
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Musculoskeletal Pain
Targeted Physiotherapeutic Treatment for Aromatase Inhibitor-associated Musculoskeletal Pain in Breast Cancer Survivors
The primary objective of this trial is to assess the efficacy of targeted individualised physiotherapeutic treatment on aromatase inhibitor-associated musculoskeletal pain.
- Trial name
- AIMSS (NCT04560699)
- Testing
- Physiotherapeutic treatment and medical care, medical care
- Where
- Denmark
- Volunteers
- 111 people
- Sponsor
- Frederiksberg University Hospital
Post-Mastectomy Chronic Pain Syndrome (Disorder)
Cryoablation for Post Mastectomy Pain Syndrome
This is a prospective, randomized, parallel-group, treatment control trial with cross-over options performed at four sites. The purpose of this study is to assess the efficacy and safety of cryoablation therapy for the treatment…
- Trial name
- NCT03293940
- Testing
- Cryoablation, Therapeutic Peripheral Nerve Block (tPNB) Injection
- Where
- 4 sites in United States
- Volunteers
- 35 people
- Sponsor
- Emory University
Post-operative Pain, Serratus Block
The Effects of Serratus Plane Block Performed Under Direct Vision on Post-operative Pain in Breast Surgery
The aim of the study is to determine the effectiveness of serratus place block in the control of post-operative pain following mastectomy.
- Conditions
- Post-operative Pain, Serratus Block, Breast Surgery
- Trial name
- NCT02555423
- Testing
- Local anaesthetic - chirocaine
- Sponsor
- Kingston Hospital NHS Trust
Mastodynia
Evaluation of Sleep Quality, Nutrition, Anxiety and Depression in Mastalgia
The aim of this study is to investigate the sleep quality, anxiety and depression levels in women with mastalgia using internationally validated scales.
- Trial name
- NCT04690218
- Testing
- Hospital anxiety and depression scale, Pittsburgh Sleep Quality Index, Nutritional Status Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Pain, Postoperative, Length of Stay
ICNBs for Post-op Pain in Breast Surgery
The authors will conduct this study to analyze the effectiveness of peri-operative intercostal nerve blocks (ICNBs) in reducing acute postoperative pain after reconstructive breast surgery and mammoplasty and how it affects the…
- Trial name
- NCT04606836
- Testing
- Bupivacaine Hydrochloride
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Christine M. Kleinert Institute for Hand and Microsurgery
Postoperative Pain Breast Reduction, Mammaplasty
SPSIP Block for Pain Control After Breast Reduction Surgery
The goal of this clinical trial is to learn whether an ultrasound-guided serratus posterior superior intercostal plane block (SPSIP block) can lower the need for opioid pain medicine after breast reduction surgery.
- Conditions
- Postoperative Pain Breast Reduction, Mammaplasty, Analgesia, Nerve Block
- Trial name
- SPSIP-RM (NCT07657949)
- Testing
- Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block, Standard Perioperative Pain Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cumhuriyet University Hospital
Breast Diseases, Mastodynia
Focal Breast Pain: Does a Normal Ultrasound Provide Reassurance?
The investigator hypothesizes that a benign directed ultrasound, when performed after a normal digital mammogram, will provide women with focal breast pain additional reassurance that the etiology of their symptom is benign.
- Conditions
- Breast Diseases, Mastodynia, Anxiety
- Trial name
- NCT02810236
- Testing
- Ultrasound, Discussion
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Duke University
Mammographic Breast Density
Study of the Effects of Cyclodynon on Reducing the Cumulative Risk of Breast Cancer Development in a Female Aged 40-52
Increased mammographic density of mammary gland tissues and hyperprolactinaemia are regarded as one of the risk factors for the development of breast cancer in women aged 40 to 52 years, which necessitates closer monitoring of…
- Trial name
- BIO-CYCL (NCT04498013)
- Testing
- Cyclodynon, Lifestyl modification
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Dr. Struk Tetiana
Breast Pain
Premedication to Reduce Discomfort With Screening Mammography
This study will explore the effect of pre-medication with acetaminophen, ibuprofen, and topical lidocaine gel (Topicaine) on the perception of discomfort and overall satisfaction with the mammography experience.
- Trial name
- NCT00382083
- Testing
- 1000 mg acetaminophen, 800 mg ibuprofen, 1 oz 4% lidocaine gel
- Where
- United States
- Sponsor
- Mountain States Tumor and Medical Research Institute
Breast Cancer, Survivorship
Dance Study for Post-surgical Pain in Breast Cancer Survivors
The purpose of this study is to examine how a 12-week, virtual dance program may improve pain and quality of life in participants with persistent post-surgical pain, or PPSP, following mastectomy or lumpectomy.
- Conditions
- Breast Cancer, Survivorship, Pain, Postoperative
- Trial name
- NCT06758102
- Testing
- Dance Program
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Mastalgia
Electromyography of the Pectoral Muscle in Mastalgia Patients
Mastalgia is a common problem for women. The aim of this study is to investigate the role of neuromuscular pathologies of the thorax wall at mastalgia ethiopathogenesis.
- Trial name
- NCT02784379
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Breast Cancer
The Effect of Ultrasonography-guided Fascial Plane Blocks in Breast Cancer Surgery Patients
The aim of this study was to evaluate the efficacy of serratus anterior plane (SAP) block, pectoserratus plane (PECS II) block, and erector spinae plane (ESP) block on postoperative acute pain, quality of recovery and chronic…
- Trial name
- NCT06419504
- Testing
- SAP block group, PECS II block group, ESP block group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Antalya Training and Research Hospital
Breast Cancer
Clinical Trial Evaluating the Efficacy and Implementation of an Early Adapted Physical Activity to Prevent and Manage Aromatase Inhibitor-induced Musculoskeletal Pain in Breast Cancer (APIS)
Aromatase inhibitors (AI) are the standard adjuvant hormone therapy for postmenopausal women with hormone-sensitive breast cancer.
- Trial name
- APIS (NCT07295457)
- Testing
- Adapted Physical Activity started early, Adapted Physical Activity begins at the start of hormone therapy
- Where
- 2 sites in France
- Volunteers
- 182 people
- Sponsor
- Hospices Civils de Lyon