Clinical trials: Maternal Obesity
Obesity, Pregnancy
CO-OP Trial: Community-based Outreach on Obesity in Pregnancy
Obesity is becoming more common and disproportionately affects the younger generation, the poor and certain ethnic groups. Nearly 50% of reproductive aged women are obese or overweight.
- Trial name
- CO-OP (NCT01841424)
- Testing
- Dietary counseling. Maintain a food diary.
- Where
- 2 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Missouri, Kansas City
Obesity & Overweight
Healthy Eating for My Infant: A Community- Informed Infant Obesity Prevention Program Addressing the Impact of Maternal Mental Health on Eating and Feeding
Infants from low-income families are at increased risk for obesity, but obesity prevention programs tailored specifically to the needs of these infants are lacking.
- Trial name
- NCT07284108
- Testing
- Healthy Eating for My Infant (HEMI)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Iron Deficiency Anemia of Pregnancy
Adiposity and Iron Requirements in Pregnancy
This study aims to explore how body fat influences the response to either 25 or 50 mg of daily iron supplements during pregnancy.
- Trial name
- ADIPREG (NCT06425796)
- Testing
- Adiposity and Iron Requirements in Pregnancy (ADIPREG)
- Where
- 3 sites in United Kingdom
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Overweight or Obesity
NDPP-NextGen: A Clinical Trial to Reduce Intergenerational Obesity and Diabetes Risks
The goal of this clinical trial is to test an enhanced version of the National Diabetes Prevention Program (NDPP-NextGen) that is tailored to young women in childbearing years.
- Trial name
- NCT05674799
- Testing
- NDPP-NextGen
- Where
- United States
- Volunteers
- 403 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Obesity, Obesity, Maternal
Obesity and OSA in Pregnancy
The purposes of this project are 1) to compare the impact of maternal obesity versus excessive gestational weight gain on obstructive sleep apnea (OSA) in obese and non-obese women; 2) to investigate the mechanism(s) by which…
- Conditions
- Obesity, Obesity, Maternal, Obstructive Sleep Apnea, Blood Pressure
- Trial name
- NCT05654259
- Where
- 2 sites in United States
- Volunteers
- 116 people
- Sponsor
- University of Texas Southwestern Medical Center
Overweight, Obesity
Iron Absorption and Transfer to the Fetus During Pregnancy in Normal Weight and Overweight/Obese Women and the Effects on Infants Iron Status
Overweight and obesity causes low-grade systemic inflammation, which sharply increases risk for iron deficiency. Studies in our laboratory have shown that this is mainly the result of reduced dietary iron absorption because of…
- Conditions
- Overweight, Obesity, Pregnancy
- Trial name
- PIANO (NCT02747316)
- Testing
- Stable iron isotope 57 (57Fe) labeled iron solution, Stable iron isotope 58 (58Fe) labeled iron solution
- Where
- Switzerland
- Volunteers
- 83 people
- Sponsor
- Swiss Federal Institute of Technology
Diabetes Mellitus, Type 2, Pregnancy in Diabetic
The Effect of In-utero Exposure to Metformin in 5-11 Year Old Offspring of Mothers in the MiTy Trial
The incidence of diabetes in pregnancy is rising, with rates of 1 in 7 pregnancies globally. Metformin is used for type 2 diabetes (T2DM) outside of pregnancy and is now increasingly prescribed during pregnancy.
- Conditions
- Diabetes Mellitus, Type 2, Pregnancy in Diabetic, Child Obesity, Child Development
- Trial name
- MiTy Tykes (NCT05025852)
- Where
- 12 sites in Australia, Canada
- Volunteers
- 132 people
- Sponsor
- Mount Sinai Hospital, Canada
Dental Caries, Obesity Risk
Mothers' Action Project for Child Health
This randomized controlled trial will recruit Bangladeshi mothers and their young children into a 12 month intervention that provides child health and oral health education and seeks to build social networks among mothers.
- Trial name
- MAP-CH (NCT06753669)
- Testing
- health education and social network building, dental referral and educational materials
- Where
- United States
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Childhood Obesity
Exercise and Behavioral Therapy in Obese Children
The aim of this study is to compare the effects of exercise training and family-based behavioral treatment, either in individual or in group setting, in pre-pubertal children and their mother.
- Trial name
- NCT01506245
- Testing
- Family-based behavioral therapy
- Where
- Switzerland
- Volunteers
- 75 people
- Sponsor
- University Hospital, Geneva
Pregnancy Related, Adolescent Obesity
#BabyLetsMove Physical Activity Feasibility Trial
Black adolescents who are pregnant represent a high-risk and understudied perinatal population in health research. Adolescent pregnancy (<20 years) is disproportionately prevalent among Blacks compared with Whites and is a…
- Conditions
- Pregnancy Related, Adolescent Obesity, Behavior, Health, Behavior, Sedentary
- Trial name
- NCT04628065
- Testing
- #BabyLetsMove
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Pregnancy Complication
Influence of Preconceptional Obesity on the Myometrial Cells Differentiation Toward a Contractyl Phenotype
The purpose of this study is to improve the understanding of cellular mecanism involved in delivery disorders in obese women, first by characterizing the hyperplasia phenomenon of myometrail cells induced by inflammatory…
- Trial name
- ObeDi (NCT01762683)
- Testing
- Myometrium biopsy and blood samples
- Where
- 2 sites in France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Weight Gain
Sleep-Safe: A Strong African American Families Study
Rapid weight gain during infancy is a powerful, and potentially malleable, risk factor for later overweight and obesity, but limited research has examined the impact of promising interventions when applied to the groups most at…
- Trial name
- NCT03505203
- Testing
- Sleep Soothe, Sleep Safe
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Pregnancy Related, Obesity, Maternal
Remotely Monitored Exercise Program in Pregnant Women With Obesity
Pregnant women with obesity will be invited to participate in structured home-based exercise programme, remotely monitored
- Trial name
- GROB (NCT05331586)
- Testing
- Remote Exercise
- Where
- Portugal
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Adiposity
Maternal Lipids and Offspring Adiposity at 5-7 Years
This study investigates the associations between measured maternal lipids (Total cholesterol, LDL-cholesterol , triglycerides and high-density lipoprotein cholesterol) at 28 weeks' gestation and offspring adiposity at 5-7 years.
- Trial name
- HAPO (NCT03317522)
- Volunteers
- 1,224 people, healthy volunteers welcome
- Sponsor
- Belfast Health and Social Care Trust
Maternal Obesity During Childbirth, Labor; Arrested Active Phase
Impact of Maternal BMI on Plasma Levels of Oxytocin During Labor Augmentation
The aim of this study is to examine the associations between maternal BMI and levels of oxytocin in maternal plasma during augmentation with oxytocin during first stage of labor in term pregnancy.
- Trial name
- NCT04093479
- Testing
- blood samples
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Linkoeping University
Labor Long
The Use of Peanut Ball in Labor in Obese Women
The purpose of this study is to assess the efficacy of peanut ball use on labor process and maternal, neonatal outcomes in obese pregnant women.
- Trial name
- NCT05276947
- Testing
- position with peanut ball
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Gulhane Training and Research Hospital
Neonatal Hypoglycemia, Gestational Diabetes
Accuracy of Interstitial Continuous Glucose Sensors in Neonates
Low blood sugar in newborns is common and if prolonged or untreated may place them at increased risk for later learning and behavior challenges.
- Conditions
- Neonatal Hypoglycemia, Gestational Diabetes, Maternal Obesity Complicating Pregnancy, Small-for-gestational Age
- Trial name
- NCT07133906
- Testing
- Continuous glucose monitoring, Cerebral near-infrared spectroscopy
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Fetal Weight, Obesity, Morbid
Comparison of Three Methods for Fetal Weight Estimation
The aim of this study was to compare maternal, clinical and ultrasound estimations of fetal weight in women with severe (BMI>35) and morbid (BMI>40) obesity and to determine the effect of maternal body mass index (BMI) on these…
- Conditions
- Fetal Weight, Obesity, Morbid, Pregnancy Related
- Trial name
- NCT05478798
- Testing
- ultrasonographic fetal weight estimation, clinical fetal weight estimation, maternal subjective fetal weight estimation
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Obesity, Diabetes
Role of Nutrition and Maternal Genetics on the Programming of Development of Fetal Adipose Tissue
In the PREOBE projects it is aimed to obtain genetic and biochemical biomarkers for the programming of obesity in early stages of life.
- Trial name
- PREOBE (NCT01634464)
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Obesity, Pregnancy
Gestational Obesity and Interventions With Probiotics or Fish Oil Trial
Obesity is one of the most concerning health issues in the modern world, especially due to its association with greater risk of developing a wide range of chronic diseases.
- Conditions
- Obesity, Pregnancy, Inflammation
- Trial name
- GOPROFIT (NCT03215784)
- Testing
- Fish Oil, Probiotic
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro