Clinical trials: Mature Teeth
Pulpitis
MMP-9 Expression in Permanent Mature Teeth With Symptomatic Pulpitis
Matrix metallopeptidase-9 (MMP-9) expression was compared in healthy and inflamed pulp and the outcome of coronal pulpotomy in teeth with symptomatic pulpitis was assessed.
- Trial name
- NCT03807674
- Testing
- Coronal pulpotomy
- Where
- Lithuania
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Eglė Gvazdaitytė
Pulpal Necrosis
The Use of Platelet Rich Fibrin in Pulpal and Periodontal Regeneration in Mature Teeth
In cases of permanent tooth avulsion, it is widely accepted that some necrosis always occurs after avulsion injury. If the pulp tissue does not revascularize or if endodontic therapy is not performed, the pulp space can become…
- Trial name
- NCT02477358
- Testing
- Left Tooth Platelet Rich Fibrin; Right Tooth Implant Alone, Right Tooth Platelet Rich Fibrin; Left Tooth Implant Alone
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Apical Periodontitis
Assessment of Regenerative Potential of Mature Permanent Teeth With Necrotic Pulps Using Two Revascularization Protocols. (In Vivo Study)
Regenerative endodontic procedures have been used to successfully treat human mature permanent teeth with necrotic pulps and apical periodontitis.
- Trial name
- NCT04158232
- Testing
- Method
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Minia University
Irreversible Pulpitis
The Influence of Magnification and Clinical Experience on the Outcome of Pulpotomy in Mature Adult Teeth
The goal of this interventional randomized clinical trial is to test the effect of magnification and clinical experience of the operator on the success rate of full pulpotomy in mature adult molar teeth.
- Trial name
- NCT06231290
- Testing
- Adult full pulpotomy procedure
- Where
- Egypt
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Irreversible Pulpitis
Evaluation of Two Different Calcium Silicate Cements as a Treatment for Irreversible Pulpitis in Mature Molars
This randomized controlled clinical trial aims to evaluate the effect of two calcium silicate cements-Biodentine and EndoCem-on post-operative pain and treatment success in vital pulp therapy (VPT) for mature permanent mandibular…
- Trial name
- NCT07066410
- Testing
- intervention 1: endocem, Intervention 1: biodentine
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Reversible Pulpitis, Irreversible Pulpitis
Clinical and Radiographic Outcomes of Pulpotomy in Teeth with Different Symptoms and Root Stages
Pulpotomy is a vital pulp therapy (VPT) method used to maintain pulp vitality by removing inflamed or infected coronal pulp tissue while preserving the health and function of radicular pulp.
- Conditions
- Reversible Pulpitis, Irreversible Pulpitis, Mature Teeth, Immature Teeth
- Trial name
- NCT06874088
- Testing
- Pulpotomy with Calcium Silicate-Based Bioceramics in Permanent Teeth
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Muhammed Alagöz
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Concerned Growth Factor Versus Miniral Trioide Aggregate in Management of Mature Permanent Molar With Irreversible Pulpitis
Concerned Growth Factor VS Miniral Trioide Aggregate in Treatment of Mature Permanent Teeth of Children With Symptomatic Irreversible Pulpitis.
Concerned Growth factor versus Miniral Trioide aggregate in management of Mature permanent Molar of children with irreversible pulpitis
- Trial name
- NCT07138287
- Testing
- Concerned Growth factor in management of Mature permanent Molar with irreversible pulpitis
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Minia University
Pulp Revascularization
Outcome of Pulp Revascularization of Necrotic Mature Permanent Teeth Using Platelet-rich Fibrin
Regenerative endodontic procedures are intended to replace damaged tooth structures, including dentine and root structures, in addition to cells of the pulp-dentine complex.
- Trial name
- NCT06347640
- Testing
- induced bleeding, plasma rich fibrin
- Where
- Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Pulpitis - Irreversible
A-prf,Nanochitosan Combined With A-prf Compared to Chitosan for Symptomatic Irreversible Pulpitis of Mature Teeth
Clinical and radiographic assessment of A-prf,A-prf combined with nanochitosan compared to chitosan for symptomatic irreversible pulpits in lower permanent first molar
- Trial name
- NCT06438523
- Testing
- PULPOTOMY OF MATURE PERMENANT TEETH
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Dental Pulp Capping, Dental Caries Extending to Pulp
Long-term Evaluation of Direct Pulp Capping
Calcium hydroxide and mineral trioxide aggregate have been used in vital pulp therapy with variable outcomes recorded by different study.
- Trial name
- NCT03403985
- Testing
- Calcium Hydroxide (Ca(OH)2), Mineral Trioxide Aggregate
- Where
- Jordan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Necrotic Pulp, Periapical; Infection
Volume Assessment of the Periapical Healing Following Regenerative Endodontic Procedures Using Cone- Bean Computed Tomography
3D volume assessment was done to evaluate the periapical healing following REPs in mature teeth.
- Trial name
- NCT04646538
- Testing
- Regenerative Endodontics Procedures (REPs)
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Irreversible Pulpitis
Outcome Following Use of NaOCl and Chlorhexidine as Wound Lavage Agents
The goal of this clinical trial is to to compare effect of wound lavage agents NaOCl and Chlorhexidine on the outcome of partial pulpotomy in mature permanent posterior teeth with signs and symptoms indicative of irreversible…
- Trial name
- NCT06240130
- Testing
- Partial pulpotomy
- Where
- India
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Deep Caries
Direct Pulp Capping Compared to Partial Pulpotomy in Carious Pulp Exposures
This a prospective randomized clinical trial that compare vital pulp therapy procedures in permanent teeth with carious pulp exposure.
- Trial name
- Pulp cap (NCT06495242)
- Testing
- Direct pulp capping and partial pulpotomy
- Where
- Jordan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Pulpitis
Evaluation of Pulpotomy Using Two Different Agents in Mature Anterior Teeth With Pulpitis
the study will evaluate the clinical and radiological success of mature permanent anterior teeth pulpotomy in children and adolescents with signs of pulpitis using two different Biomimetic materials (NeoPutty® and Biodentine™) as…
- Trial name
- NCT06468085
- Testing
- premixed Bioceramic NeoPUTTY®, Biodentine™, Root canal treatment
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Apical Periodontitis
Assessment of Different Disinfection Protocols on Regenerative Potential of Mature Teeth
Regenerative endodontic procedures have been used to successfully treat human mature permanent teeth with necrotic pulps and apical periodontitis.
- Trial name
- NCT05557994
- Testing
- Method
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Minia University
Pulpitis - Irreversible
Assessing Success of MTA and Pre-mixed Bioceramic in Mature Teeth With Irreversible Pulpitis With Full Pulpotomy.
Although many pulpotomy agents are commercially available, there is a dearth of clinical research comparing the efficacy of these agents in treating individuals with irreversible pulpitis.
- Trial name
- GCP (NCT05853185)
- Testing
- Pro Root MTA®, EBRRM®
- Where
- Pakistan
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences
Dental Pulp Necrosis, Dental Pulp Disease
Digitized Assessment for the Survival of Mature Anterior Teeth With Periapical Lesion After One Step Regenerative Approach Using Different Asepsis Maneuvers
Trial is designed to allow revascularization and tissue engineering in necrotic teeth with peripical lesion in a single visit approach.
- Conditions
- Dental Pulp Necrosis, Dental Pulp Disease, Dental Pulp; Degeneration
- Trial name
- RCT (NCT03652129)
- Testing
- Disinfection
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cairo University
Regenerative Endodontics
Regenerative Endodontics in Mature Permanent Teeth
this study was designed to compare the clinical and radiographic success of REPs after using blood clot scaffold in non-vital mature permanent teeth with or without photobiomodultion therapy
- Trial name
- NCT05892536
- Testing
- dental regenerative endodontics
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Salma fathy
Pulpitis - Irreversible
Partial Versus Miniature Pulpotomy in Teeth With Irreversible Pulpitis
This study will compare the outcome of partial and miniature pulpotomy in mature permanent molars with symptomatic partial irreversible pulpitis
- Trial name
- NCT05406557
- Testing
- Partial pulpotomy, Miniature pulpotomy
- Where
- India
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak