Clinical trials: Maxillary Sinus Disease
Oroantral Communication
Inverted Periosteal Flap vs Buccal Advancement Flap for Oroantral Communication Closure
This randomized controlled clinical study will evaluate the effectiveness of the inverted buccal periosteal flap in closing recent post-extraction oroantral communications and compare it with the conventional buccal advancement…
- Trial name
- NCT07630701
- Testing
- Inverted Buccal Periosteal Flap, Buccal Advancement Flap
- Where
- Syria
- Volunteers
- 24 people
- Sponsor
- Arab International University
Maxillary Sinusitis
Endosseous Oroantral Port for Minimal Intervention in Treating Chronic Sinusitis
This study is intended to evaluate the efficiency of utilizing "dynamic implant valve approach" (DIVA) system in treating chronic maxillary sinusitis.
- Trial name
- NCT03083392
- Testing
- treatment of chronic maxillary sinusitis using DIVA system, "dynamic implant valve approach" - DIVA system
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Western Galilee Hospital-Nahariya
Survival, Prosthesis, Bone Loss
Osteotome-mediated Sinus Floor Elevation With or Without Grafting Material
Implant placement in the posterior part of the maxilla is frequently compromised or impossible due to atrophy of the alveolar process and pneumatisation of the maxillary sinus.
- Conditions
- Survival, Prosthesis, Bone Loss, Patient Satisfaction
- Trial name
- NCT04618900
- Testing
- Sinus floor elevation with a grafting material
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Atrophy, Jaw, Edentulous, Partially
Comparative Results of Six Biomaterials Used in Two-stage Maxillary Sinus
Objectives: The aim of the study was to compare histological and histomorphometric results of six bone substitute materials used as graft in two-stage maxillary sinus augmentation model, after 6-month-healing.
- Conditions
- Atrophy, Jaw, Edentulous, Partially, Sinus Floor Augmentation, Bone Substitutes
- Trial name
- NCT03496688
- Testing
- Sinus floor augmentation
- Volunteers
- 6 people
- Sponsor
- University of Roma La Sapienza
Alveolar Bone Loss
Graftless Maxillary Sinus Augmentation With CGF Utilizing DIVA System
This study is intended to evaluate the efficiency of graftless maxillary sinus augmentation with concentrated growth factor (CGF) utilizing "dynamic implant valve approach" (DIVA) system.
- Trial name
- NCT02985645
- Testing
- maxillary sinus augmentation with CGF, "dynamic implant valve approach" - DIVA system
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Edentulism, Alveolar Bone Atrophy
The Influence of Dimensional Anatomic Variables on the Outcomes of Maxillary Sinus Grafting Procedures
The hypothesis of this study is that there is a significant difference in bone maturation after sinus grafting determined by the distance from the buccal to the palatal wall of this cavity.
- Conditions
- Edentulism, Alveolar Bone Atrophy, Sinus Pneumatization
- Trial name
- NCT00868777
- Testing
- Sinus grafting using allogenic bone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Michigan
Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer
This phase I/Ib trial tests the safety and best dose of ipatasertib in combination with the usual treatment approach using chemotherapy together with radiation therapy ("chemo-radiation") in patients with head and neck cancer.
- Conditions
- Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Head and Neck Carcinoma of Unknown Primary, Locally Advanced Head and Neck Squamous Cell Carcinoma
- Trial name
- NCT05172245
- Testing
- Biopsy Procedure, Biospecimen Collection, Cisplatin
- Where
- 18 sites in United States, Canada
- Volunteers
- 46 people
- Sponsor
- National Cancer Institute (NCI)
Alveolar Bone Loss, Maxillary Sinus Bone Loss
Anti-HLA Antibodies After Bone Regeneration Surgery
This study evaluates the occurrence of anti-human leukocyte antigen (anti-HLA) antibodies following bone regeneration procedures performed prior to dental implant therapy.
- Trial name
- Anti-HLA Bone (NCT07474857)
- Testing
- Xenogeneic Bone Graft, Allogeneic Bone Graft, Low-Level Laser Therapy
- Where
- Poland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical Innovation Center Wroclaw
Sinusitis
Safety and Performance of the SinuSys Dilation System for Dilation of the Maxillary Sinus Ostium
The purpose of this study is to assess safety and performance of the SinuSys Dilation System for dilation of the maxillary sinus ostium.
- Trial name
- NCT01623050
- Testing
- SinuSys Dilation System
- Where
- 5 sites in United States, Canada and 1 more
- Volunteers
- 36 people
- Sponsor
- SinuSys Corporation
Alveolar Bone Loss
Effectiveness in Limiting the Need to Elevate the Maxillary Sinus
The aim of the present study is to evaluate the effectiveness of different alveolar preservation procedures performed at the time of extraction of the first or second upper molar in avoiding a maxillary sinus elevation or at…
- Trial name
- SO-GHI (NCT03357705)
- Testing
- alveolar ridge preservation with synthetic bone, alveolar ridge preservation with bovine collagen
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Alveolar Bone Loss
Comparison of Extra-short (4 mm) Implants Used as Distal Support of a Maxillary Full-arch Fixed Dental Prosthesis vs. 10 mm Implants Installed After Sinus Floor Elevation.
Recently, 4 mm long implants with a standard diameter have been used for the restoration of the posterior edentulous mandible with favorable results.
- Trial name
- NCT03958448
- Testing
- Placement of extra short implants, maxillary sinus lift, maxillary sinus elevation, maxillary sinus augmentation, placement of standard implant
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- ARDEC Academy
Sinusitis
Maxillary Sinus Irrigation in the Management of Chronic Rhinosinusitis
The purpose of this study is to evaluate the effectiveness of maxillary sinus saline irrigation in conjunction with systemic antibiotic therapy versus systemic antibiotic therapy alone in the management of chronic rhinosinusitis…
- Trial name
- NCT00335309
- Testing
- Maxillary Sinus Irrigation, IV Amoxicillin and Clavulanate acid
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Ohad Ronen
Edentulous Posterior Maxilla, Maxillary Sinus Pneumatization
Graftless TSFE Via Self-tapping Implants
This prospective clinical trial aims to evaluate the efficiency, safety, and reliability of a minimally invasive graftless transcrestal sinus lifting approach with simultaneous dental implant placement in patients with edentulous…
- Conditions
- Edentulous Posterior Maxilla, Maxillary Sinus Pneumatization, Alveolar Bone Atrophy
- Trial name
- G-TSFE (NCT07424742)
- Testing
- Graftless Transcrestal Sinus Membrane Elevation with Simultaneous Implant Placement
- Where
- Yemen
- Volunteers
- 20 people
- Sponsor
- Sana'a University
Disorder of Maxillary Sinus, Accessory; Bone
Comparative Study Between Lyophilized or Frozen Bone Allografts for Sinus-lifting
Bone resorption and atrophy in maxillary posterior region is due to severe periodontal disease and is consequent tooth extractions. Sinus pneumatisation can occur after tooth extraction and alveolar bone loss.
- Conditions
- Disorder of Maxillary Sinus, Accessory; Bone, Bone Atrophy
- Trial name
- NCT02583737
- Testing
- freeze bone allograft, lyophilized bone allograft
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Maxillary Sinus Disease
Maxillary Sinus Floor Elevation With Gelatin Sponge Versus Allogenic Demineralized Bone Matrix
The post-extraction pneumatization of the maxillary sinus often compromises the ability of the maxillary molar to the optimal recipient of dental implants as a consequence of the quantitative reduction of the vertical bone height…
- Trial name
- NCT06681857
- Testing
- Sinus lifting
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Partially Edentulous Maxilla, Alveolar Bone Atrophy
Effectiveness and Safety of Method of Maxilla Alveolar Process Reconstruction Using Synthetic Tricalcium Phosphate and Autologous MMSCs
Autologous MMSCs will be isolated from oral mucosa biopsy sample and expanded in vitro.Tissue engineered construction will be created using synthetic tricalcium phosphate and autologous MMSCs.
- Conditions
- Partially Edentulous Maxilla, Alveolar Bone Atrophy, Alveolar Bone Loss
- Trial name
- NCT02209311
- Testing
- Oral mucosa biopsy, Sinus lift with implantation of tissue engineered construction, Dental implant
- Where
- 2 sites in Russia
- Volunteers
- 12 people
- Sponsor
- Central Clinical Hospital w/Outpatient Health Center of Business Administration for the President of Russian Federation
Tooth Loss
Evaluation of a Lateral Window Technique Augmentation for Maxillary Sinus Using Ultrasound Activated Pins
Ultrasound activated pins have been used for the promotion of bone healing in combination with biodegradable membranes during bone grafting procedures.
- Trial name
- NCT02449707
- Testing
- Lateral Window Technique Augmentation for Maxillary Sinus, Ultrasound activated resorbable poly-D-L-lactide pins, Purus® Cancellous Allograft
- Where
- Saudi Arabia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Atrophic Maxilla, Zygomatic Implants
Computer Guided Placement of Zygomatic Implants in Two Different Approaches
Evaluation of computer guided placement of Zygomatic implants utilizing intra sinus versus extra sinus surgical approach for the reconstruction of atrophic maxilla.
- Trial name
- NCT06129695
- Testing
- Zygomatic implants
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Maxillary Sinus Disease
Isolated Maxillary Sinus Lesions in Sohag University Hospital
Aim of the study: Identify variants of maxillary sinus pathologies, its clinical presentations, radiological findings and surgical managements.
- Trial name
- NCT06556225
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Oroantral Communication, Acute Oroantral Communication
Acute Oroantral Communication Closure: Resorbable Collagen Membrane vs. Buccal Advancement Flap Outcomes
Oroantral communication (OAC) is an abnormal opening between the oral cavity and the maxillary sinus that may occur after extraction of posterior maxillary teeth.
- Conditions
- Oroantral Communication, Acute Oroantral Communication, Oroantral Fistula, Post-extraction Maxillary Sinus Communication
- Trial name
- AOC (NCT07476664)
- Testing
- Resorbable collagen membrane OAC closure, Buccal advancement flap OAC closure
- Where
- Poland
- Volunteers
- 24 people
- Sponsor
- Medical University of Silesia