Clinical trials: Maxillofacial Injury
Mandible Fracture
Stability of Angle Fracture Fixation With (K) Shaped Titanium Miniplates Versus Two Miniplates
In patients with angle fracture , will the (K) shaped titanium miniplates provide more stable fixation than two conventional miniplates? Many studies have been conducted to compare between different techniques of fixation used in…
- Trial name
- NCT03839368
- Testing
- fixation of angle fracture
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Exophthalmos, Graves Ophthalmopathy
Exophthalmometry With 3D Face Scanners
This study investigates diagnostic methods to measure eyeball protrusion with a smartphone face scanner compared to the traditional Hertel exophthalmometer.
- Conditions
- Exophthalmos, Graves Ophthalmopathy, Orbital Tumor, Orbital Fractures
- Trial name
- EX3D (NCT04704414)
- Testing
- Exophthalmos measurement
- Where
- Switzerland
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Mandibular Fractures
Computer Guided Screw Holes Locating Guide and Custom-made Plates
Preoperative CT. Virtual reduction of broken segments on software. Gain occlusion. Design surgical screw holes locating guide. Design the custom-made plates. Print the screw holes locating guide and the custom-made plate.
- Trial name
- NCT05647460
- Testing
- computer guided screw holes locating guide and custom-made plates, conventional plates
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Blood Loss
Effect of Perioperative Tranexamic Acid on Blood Loss During Management of Maxillofacial Trauma
This is a prospective, randomized, double-blind study investigating whether intravenous tranexamic acid has any effect on blood loss during maxillofacial trauma surgery, or the subsequent postoperative sequelae.
- Trial name
- NCT04494126
- Testing
- Tranexamic acid
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- College of Medical Sciences Teaching Hospital. Nepal
Maxillofacial Trauma, Face Cancer
Evaluation of Using 3D Printed PEEK Facial Implants in Repairing Maxillofacial Deformities
Objective: Evaluation of using 3D printed polyether ether ketone facial implants in repairing maxillofacial deformities. Research materials and methods: The research sample consisted of 10 patients with facial deformities…
- Conditions
- Maxillofacial Trauma, Face Cancer, Mucormycosis
- Trial name
- NCT05348434
- Testing
- 3D printed polyether ether ketone facial implants in repairing maxillofacial deformities
- Where
- Syria
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Latakia University
Cleft Palate, Plasma Rich in Growth Factors
Role of Plasma Rich Growth Factor in Repair Primary Cleft Palate
Does the plasma-rich growth factor (PRGF) with primary cleft palate repair accelerate wound healing and prevent post-operative oronasal fistula occurrence?
- Trial name
- PRGF (NCT06889181)
- Testing
- Plasma Rich in Growth Factors (PRGF)
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postoperative Pain, Mandible Fracture
Postoperative Pain After Bupivacaine Supplementation in Mandibular Fracture Surgery
Pain following open reduction of mandibular fractures is the most reported complaint during the first 24 post-operative hours. The goal of this clinical trial is to evaluate the impact of inferior alveolar nerve block with…
- Conditions
- Postoperative Pain, Mandible Fracture, Analgesia, Anesthesia, Local
- Trial name
- NCT06243263
- Testing
- Bupivacain
- Where
- 2 sites in Tunisia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Orbital Fractures
Clinical Outcomes of Transconjunctival Vs Transcutaneous Approaches in Orbital Fracture Repair
Open reduction and internal fixation of zygomaticomaxillary complex (ZMC) fractures has a challenging impact on the selection of the suitable surgical approach to the orbital and zygomatic skeleton.
- Trial name
- Vs: versus (NCT07759440)
- Testing
- orbital fracture reduction and fixation
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Blow-Out Fractures, Orbital Fractures
Accuracy& Orbital Volume Using Patient Specific Titanium Implant Vs Zirconia for Orbital Floor Reconstruction
Comparative study used to assess if the patient specific zirconia implant will provide better accuracy, intraoperative adaptability, precise orbital volume and soft tissue reaction with more cost effectiveness than the patient…
- Conditions
- Blow-Out Fractures, Orbital Fractures, Orbital Floor Fracture, Orbital Trauma
- Trial name
- NCT06369129
- Testing
- Orbital floor reconstruction with Patient Specific Zirconia Implant, Orbital floor reconstruction with Patient Specific Titanium Implant
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Facial Nerve Injuries, Mandibular Fractures
Safety-zone Approach and Facial Nerve Preservation in Transbuccal-accessed Fixation of Mandibular Fractures
The goal of this study is to investigate the efficacy of a safety-zone that is anatomically landmarked on the face of patients with mandibular fractures that are approached transbuccally (through cheek) on postoperative…
- Conditions
- Facial Nerve Injuries, Mandibular Fractures, Surgical Incision
- Trial name
- NCT07807813
- Testing
- Landmarking Safety-zone
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
Zygoma Fracture
Outcomes of Zygomatic Fractures: Cross- Sectional Study
Rationale: Facial trauma is a significant event for patients, often resulting in physical and psychological consequences. Fractures in the zygomatic bone area are common due to its unique shape and positioning in the face…
- Trial name
- ZY-PROM (NCT06476340)
- Testing
- No intervention
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Mandibular Fractures
Assessment of Serum Concentration of Interleukin-17 and Osteoprotegerin in Response to Surgical Trauma Induced by Management of Mandibular Fractures Via Intraoral Versus Extraoral Approaches: Prospective Cohort Study
Assessment of Serum Concentration of Interleukin-17 and Osteoprotegerin in Response to Surgical Trauma Induced by Management of Mandibular Fractures via Intraoral Versus Extraoral Approaches: Prospective Cohort Study
- Trial name
- NCT06349135
- Testing
- Open Reduction & Internal Fixation
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Aya Ayman Ahmed
Orbital Trauma, Orbital Fractures
Reconstruction of the Orbit With a Bioresorbable Polycaprolactone Implant
Patients with orbital injuries are entered into the trial. Age: 20 - 70. After obtaining appropriate consent, they are entered into either a control arm where reconstruction of the orbit is done with a titanium mesh (established…
- Trial name
- NCT00233922
- Testing
- Osteosheet(r)
- Where
- Singapore
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Mandibular Fractures, Facial Injuries
Aetiology and Pattern of 122 Patients With Mandibular Condylar Fracture
This retrospective observational study aimed to investigate the aetiology and fracture patterns among patients with mandibular condylar fractures (MCF) who were treated at a trauma center in Shiraz, Iran, between 2018 and 2020.
- Trial name
- NCT07099833
- Testing
- Azita Sadeghzade
- Where
- Iran
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Azita Sadeghzade
Orbital Fractures
Using the Transconjuctival Approach Alone Versus Using it Together With Lateral Canthotomy in Orbital Fractures
All cases will undergo surgery under general anesthesia. Evaluation of patients with suspected orbital fracture should involve radiologic examination, motility test, diplopia field test and exophthalmometry.
- Trial name
- NCT03813732
- Testing
- orbital fracture
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bone Loss, Jaw, Edentulous
Effectiveness of 3D-printed Patient-specific Resorbable Scaffolds for Maxillary Bone Regeneration
The objective of this study is to test the bone formation capacity of a 3D printed scaffold with a plastic material called Polycaprolactone (PCL), compared to the use of synthetic bone grafts, for bone formation in the maxilla or…
- Conditions
- Bone Loss, Jaw, Edentulous, Edentulous Mouth, Jaw Fractures
- Trial name
- OSTEOPRINT (NCT06773923)
- Testing
- PCL Scaffold, PTFE + Bio-Oss®
- Where
- Chile
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidad Austral de Chile
Hemoglobin Level Measurement, Blood Loss During Surgery
Efficacy of Tranexamic Acid Reducing Blood Loss During Maxillofacial Trauma Surgery
Tranexamic acid (TXA) is an inexpensive, easily used and relatively safe drug. It inhibits plasminogen activation and plasmin thus retards clot disintegration.Therapeutic application of tranexamic acid in trauma for preventing…
- Conditions
- Hemoglobin Level Measurement, Blood Loss During Surgery, Duration of Surgery
- Trial name
- NCT07392034
- Testing
- Tranexamic Acid (TXA), Normal saline
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nishtar Medical University
Maxillofacial Trauma
Assessment of Healing Properties Using Hyaluronic Acid Topical Application in Parasymphyseal Fracture Fixation: A Randomized Clinical Trial
HA is favorable for osteogenesis, enhancing bone growth, acting a vector for osteoinductive compounds and promoting even distribution and increased density of newly formed bone, thereby altering the scaffold morphology and…
- Trial name
- NCT06221527
- Testing
- conventional group
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Mandibular Fractures
Approaches for Open Reduction and Internal Fixation of Mandibular Condylar Fracture
The condylar region is the most frequent anatomical site for mandibular fractures . Condylar fractures constitute 25.5% to 35.5% of all mandibular fractures.
- Trial name
- NCT06333197
- Testing
- ORIF through transparotid approach, ORIF through retroparotid approach
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Therapeutics of Bilateral Maxillofacial Injuries
Treatment of Bilateral Maxillofacial Post-traumatic Deformities
Combined application of surgery planning software and rapid prototyping technology and preshaped titanium plates can effectively promote the accuracy of the diagnosis and treatment of bilateral maxillofacial post traumatic…
- Trial name
- NCT01875887
- Testing
- rapid prototyping technology
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- West China Hospital