Clinical trials: Maxillofacial Surgery
Dentofacial Deformity
Lower Laser Therapy in Orthognathics Surgery
This study will examine the use of lower laser therapy to reduce edema and pain in orthognathics surgery.
- Trial name
- NCT01530100
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Third Molars Extraction, Oral Health-Related Quality of Life
Effects of Irrigation Solutions at Different Temperatures Used in Mandibular Third Molar Surgery
The present study aims to compare the effects of saline, chlorhexidine, and hydrogen peroxide irrigation solutions at different temperatures on postoperative complications, including pain, swelling, and mouth opening, as well as…
- Conditions
- Third Molars Extraction, Oral Health-Related Quality of Life, Postoperative Complications in Maxillofacial Surgery, Irrigation Solution
- Trial name
- NCT07835958
- Testing
- 4°C sterile saline solution, 25°C sterile saline solution, 4°C 0.2% chlorhexidine solution
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Cleft Palate Children
Length of Hospital Stay and Postoperative Analgesic Requirements After Introduction of a Specific Maxillary Nerve Block in Children Undergoing Cleft Palate Surgery
Cleft lip and palate (CLP) is one of the most common congenital malformations and requires repeated surgical correction during childhood.
- Trial name
- NCT07279883
- Where
- Sweden
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Mandibular Hypoplasia
Comparing Stability and Cost-Effectiveness of 3 Bicortical Screws Vs Adjustable Plate and 2 Bicortical Screws in Fixation of BSSRO
In this current study a comparison between 3 positional screws versus the adjustable plating system in conjunction with 2 positional screws. The patients will be selected to have retrognathic mandible requiring advancement.
- Trial name
- NCT02950727
- Testing
- 3 bicortical screws, adjustable plate and 2 bicortical screws
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Joseph Van Sickels
Dentofacial Deformities
3D Photogrammetry Versus Commercial Scanners for Accurate Repositioning of the Maxilla for Correction of the Dentofacial Deformity.
Current advances in the three-dimensional virtual surgical planning (3D-VSP) of the orthognathic surgery have brought newer insights, enormous benefits and have become an indispensable aid for diagnosis, treatment planning and…
- Trial name
- NCT05755022
- Testing
- Maxillary Segment Repositioning
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Epistaxis
Nasal Intubation Using a Parker Flex-tip Endotracheal Tube Compared to a Nasal RAE Tube
The purpose of this study is to determine the degree of epistaxis following nasal intubation with either a nasal endotracheal (RAE) tube with bevel facing left or Parker Flex-Tip endotracheal tube with bevel facing posteriorly…
- Trial name
- NCT02315677
- Testing
- Nasal Intubation with nasal RAE endotracheal tube, Nasal Intubation with Parker Flex-Tip endotracheal tube
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Cleft Palate
Suprazygomatic Block in Cleft Palate Surgery in Children
Cleft palate (CP) is a common congenital malformation, with an incidence ranging from 0.1 to 1.1 per 1000 births depending on the population group (liau et al, 2010).
- Trial name
- NCT03412474
- Testing
- Bupivacaine, Dexmedetomidine, paracetamol
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pain, Oral Surgery
Hyaluronic Acid and Amino Acid Gel Applied to the Alveolar Socket After Mandibular Third Molar Extraction
Objective: The study aimed to assess the effect of topical application of an amino acid + sodium hyaluronate acid gel after lower third molar extraction.
- Conditions
- Pain, Oral Surgery, Third Molar Extraction
- Trial name
- NCT03428698
- Testing
- Aminogam
- Where
- Italy
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Padova, School of Dental Medicine
Oral Health Care
The Effect of Supplementary Foods Containing Trypsin, Chymotrypsin and Serratia Peptidase on Healing After Impacted Wisdom Tooth Surgery
Introduction: The aim of this study was to determine the effects of a dietary supplement containing trypsin, chymotrypsin, and serratia peptidase (Tripser Forte N30, Incir Pharma, Turkey) on postoperative healing and to determine…
- Trial name
- Trypsin (NCT07269171)
- Testing
- Pain Assessment, Number of Analgesics Needed, Edema Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Maxillofacial Abnormalities
Mandibular Stability and Dentofacial Deformity
The present study intends to clarify whether there is positional mandibular stability in patients to be submitted to orthognathic surgery.
- Trial name
- NCT01486069
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar
Comparison of PRF and Corticosteroids in Impacted Third Molar Surgery
This prospective, randomized interventional study aims to compare the postoperative effects of standard treatment (control), platelet-rich fibrin (PRF), and PRF combined with corticosteroid treatment in patients undergoing…
- Conditions
- Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar, Impacted Wisdom Tooth
- Trial name
- NCT07742826
- Testing
- Platelet-rich fibrin (PRF), Dexamethasone, Amoxicillin/Clavulanic Acid
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Final International University
Hemoglobin Level Measurement, Blood Loss During Surgery
Efficacy of Tranexamic Acid Reducing Blood Loss During Maxillofacial Trauma Surgery
Tranexamic acid (TXA) is an inexpensive, easily used and relatively safe drug. It inhibits plasminogen activation and plasmin thus retards clot disintegration.Therapeutic application of tranexamic acid in trauma for preventing…
- Conditions
- Hemoglobin Level Measurement, Blood Loss During Surgery, Duration of Surgery
- Trial name
- NCT07392034
- Testing
- Tranexamic Acid (TXA), Normal saline
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nishtar Medical University
Anesthesia
Dexmedetomidine Sedation With Third Molar Surgery
Intravenous sedation is used frequently for the relief of pain and anxiety associated with oral surgical procedures performed under local anesthesia.
- Trial name
- NCT01017237
- Testing
- Dexmedetomidine, Midazolam, Ketamine
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Dentofacial Deformities
The Use of Bone-borne Guides in Orthognathic Surgery Cases
The present study was conducted to evaluate a new design of the intermediate stent that is used in orthognathic surgery cases requiring Le Fort I osteotomy.
- Trial name
- NCT04224805
- Testing
- Bone-borne CAD/CAM splint, 3D interocclusal conventional splint
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Anxiety, Dental
Virtual Reality Technology on Pain Perception and Anxiety Levels in Adolescents and Young Adults During Third Molar Germ Avulsion Surgery (VIDAMO)
For a long time, the fear of the dental surgeon has been the main reason why a percentage of the population avoids regular consultation.
- Trial name
- VIDAMO (NCT04609956)
- Testing
- Virtual reality, Standard
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Maxilla; Hypoplasia
Transverse Maxillary Expansion With a Segmental Le Fort I Osteotomy or Surgically Assisted Rapid Maxillary Expansion (SARME)
To assess transverse dental and skeletal expansion and stability after SLFIO with no fixation of the palatal vault compared to stabilization of the palatal vault with an autogenous bone block graft or fixation of the palatal…
- Trial name
- NCT03511989
- Testing
- Bone borne distractor, Tooth borne distractor, Segmental LF1 Osteotomy group 1
- Where
- Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Pain, Other Surgical Procedures
Clinical Pharmacogenetic of Ibuprofen After Lower Third Molar Surgeries
The present clinical trial randomized will be to assess the link between the different haplotypes of CYP2C8 and CYP2C9 genes and the clinical efficacy of ibuprofen after lower third molar extractions.
- Conditions
- Pain, Other Surgical Procedures, Impacted Third Molar Tooth
- Trial name
- NCT03169127
- Testing
- Ibuprofen 600 mg
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Periimplantitis, Oral Surgery
Impact of Buccal Bone Thickness on Pathological Peri-implant Bone Loss: A 3-year Prospective Cohort Study
Implant placement may trigger bone trauma, which might result in 3-dimensional bone changes. While the process of peri-implant disease is not well understood, implant position within the bony structure might play a role.
- Trial name
- NCT02939222
- Testing
- Implant placement
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
Wound Healing, Magnesium Level
Relationship Between Magnesium Depletion Score and Extraction Socket Healing
The surgical extraction of an impacted tooth is one of the most common procedures in oral surgery. Following extraction, the tissue undergoes repair and regeneration through a process known as socket healing (SH).
- Conditions
- Wound Healing, Magnesium Level, Wisdom Tooth Removal
- Trial name
- NCT06891846
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Postoperative Infections, Mandibular Nerve Injuries
Surgeons' Prediction of Dental Surgery Complications and the Influence of Patient Characteristics: Development of an AI Model
The goal of this observational study is to learn how to better predict and prevent intra- and postoperative complications in oral surgery in adult patients referred for oral surgical procedures.
- Conditions
- Postoperative Infections, Mandibular Nerve Injuries, Alveolar Osteitis, Complication
- Trial name
- NCT07461324
- Where
- 2 sites in Denmark
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen