Clinical trials: Maximal Exercise Capacity
Healthy
Exercise-induced Changes in DNA-methylation
The purpose of the study was to investigate whether regular moderate- or high-intensity interval training can change the DNA methylation in a long-lasting state, and whether these changes affect the gene expression.
- Trial name
- NCT01931072
- Testing
- High-intensity interval training, Moderate training
- Where
- Norway
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Cystic Fibrosis
Mechanisms for Vascular Dysfunction and Exercise Tolerance in CF
Cystic fibrosis has many health consequences. A reduction in the ability to perform exercise in patients with CF is related to greater death rates, steeper decline in lung function, and more frequent lung infections.
- Trial name
- CF-AOX (NCT02690064)
- Testing
- Acute Antioxidant, Chronic Antioxidant
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Augusta University
Sleep Deprivation
Sleep and Maximal Fat Oxidation
Introduction: Despite the awareness of the importance of sleep in our lives, especially for athletes, the consequences of poor rest on sports performance are not well understood.
- Trial name
- Sleep&Fat (NCT07015008)
- Testing
- Sleep deprivation, Sleep place
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Exercise Training, Respiratory Muscle Training
Effects of High Intensity Interval Training (HIIT) vs. Inspiratory Muscle Training on the Recovery After a Maximal Apnea.
The aim of this randomized cross-over controlled study was to assess the effects of an 4-week exercise program on the recovery capacity after a voluntary maximal apnea.
- Conditions
- Exercise Training, Respiratory Muscle Training, High-Intensity Interval Training, Apnea
- Trial name
- (HIIT) (NCT04084535)
- Testing
- High intensity interval training, Inspiratory muscle training
- Where
- Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Centro Universitario La Salle
Breast Cancer, Upper Extremity
Arm Exercise Capacity and Maximal Oxygen Consumption With Breast Cancer
Breast cancer is the most common type of cancer among women worldwide. The incidence rate has reached approximately 16%. According to 2016 data from the Ministry of Health, the incidence of breast cancer in Turkey is 46.8 per…
- Conditions
- Breast Cancer, Upper Extremity, Oxygen Consumption, Healthy
- Trial name
- NCT06018038
- Testing
- Arm Exercise Capacity, Peak Oxygen Consumption (VO2peak), Muscle oxygenation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Stem Cell Transplantation
Physical Impairments in Allogeneic-HSCT
Pulmonary functions, exercise capacity and muscle strength deteriorate in survived hematopoietic stem cell transplantation (HSCT) recipients due to toxic effects of chemotherapy, radiotherapy, conditioning regimens and/or…
- Trial name
- NCT03448627
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Gazi University
Athlete
The Effect of Inspiratory Muscle Warm-up on Decreased Diffusing Capacity for Carbon Monoxide After Maximal Exercise in Athletes
This study aims to examine the effects of inspiratory muscle warm-up (IMW) on the gas exchange capacity of the lungs (DLCO) and its potential contribution to recovery and athletic performance in elite athletes from various…
- Trial name
- NCT06751511
- Testing
- General warm-up, Inspiratory muscle warm-up (%40 IMW)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Emre Karaduman
Near-Infrared Spectroscopy
Comparison of Intercostal and Quadriceps Femoris Muscle Oxygenation in Women and Men
The differences in physiological responses due to gender during exercise tests have recently begun to be investigated. The oxygen use of respiratory muscles and lower extremity muscles may differ during upper and lower extremity…
- Trial name
- NCT06896838
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Cardiovascular Diseases
Hypolipidemic and Antioxidant Capacity of Spirulina and Exercise
The purpose of this study is to demonstrate that Spirulina maxima intake and a dosed physical activity program will decrease, both independently and synergistically, cardiovascular risks (Dyslipidemias and oxidative stress) in…
- Trial name
- NCT02837666
- Testing
- Supplementation with Spirulina maxima, Washout, Isoenergetic diet
- Where
- Mexico
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Ciudad Juarez
Heart Failure Patients
Physical Impairments in Heart Failure Patients With Pacemakers
Despite major breakthroughs that have recently been made in pacemakers implanted in heart failure (HF) patients, it is clear that functional impairments and symptoms often remain.
- Trial name
- NCT03701854
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Gazi University
Transgender Persons
Transgender Observational Performance
The study will evaluate the sports capabilities of transgender women mainly in terms of muscular strength and aerobic capacity (VO2max).
- Trial name
- TOP (NCT05337865)
- Testing
- Aerobic exercise test.
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Instituto Brasileiro de Controle do Cancer
Type 1 Diabetes
Muscle Oxygenation, Type 1 Diabetes, and Glycated Hemoglobin
Most of the studies concerning aerobic fitness in Type 1 diabetic patients noted a relationship between impaired aerobic fitness and high glycated haemoglobin (HbA1c) levels, reflecting poor long term glycaemic control.
- Trial name
- OXYDIAB (NCT02051504)
- Testing
- Incremental maximal exercise, Oral Glucose Tolerance Test, Muscle biopsy
- Where
- France
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Lung Cancer
Maximal Exercise Capacity and Extra-pulmonary Characteristics in Patients With Lung Cancer With Complete Remission .
While lung cancer are rare disease in the early 20th century, its incidence increased in parallel with the increase in smoking habits. It is the most common type of cancer in the world.
- Trial name
- NCT03838757
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Gazi University
Healthy Subjects
Effect of Exercise With Low Intensity and Longer Duration Versus High Intensity Interval Training
The purpose of the study is to compare exercise at 70% of maximal heart rate were total energy expenditure is twice compared to interval training at 90- 95% of maximal heart rate.
- Trial name
- NCT01443507
- Testing
- endurance exercise of different duration and intensity
- Where
- Norway
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Volda University College
Peripheral Arterial Disease
Maximal Exercise Capacity, Physical Activity and Respiratory Muscle Strength in Peripheral Artery Disease
The primary aim of the study is to evaluate the maximal and submaximal exercise capacity in patients with peripheral artery disease (PAD).
- Trial name
- NCT03458754
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Gazi University
Chronic Venous Insufficiency
Respiratory and Physical Functions in Individuals With Chronic Venous Insufficiency
In the literature, it is still unclear whether individuals with chronic venous insufficiency are affected by edema, pain, respiratory muscle strength, respiratory functions, functional capacity, lower extremity strength and…
- Trial name
- NCT06196541
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Maximal Rate of Fat Oxidation
Dietary Correlates of the Maximal Capacity for Fat Oxidation
There is a large variability in people's ability to burn fat during exercise. It is thought that differences in dietary intake can partly explain this variation, however this has not been comprehensively studied.
- Trial name
- NCT02070055
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University of Birmingham
Obesity
Maximal Fat Oxidation and Fuel Use During Exercise
Fat and carbohydrate are the two main energy stores available as fuel during exercise. It is well known that the exercise intensity and feeding status are the major factors determining the type of fuel used during exercise.
- Trial name
- NCT04678713
- Testing
- investigate the nutritional determinants of MFO in moderate to well-train individuals, Investigate the physiological determinants of MFO in moderate to well-train individuals
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Single-ventricle, Fontan Procedure
Hemodynamic, Vascular and Muscular Parameters of Exercise Capacity in Single-Ventricle Patients With Fontan Procedure
After the Fontan procedure applied in patients with a functional or anatomical single ventricle, patients are faced with significant morbidity and mortality risk.
- Conditions
- Single-ventricle, Fontan Procedure, Hemodynamic Instability, Arterial Stiffness
- Trial name
- NCT05011565
- Testing
- Demographic and Clinical Characteristics, Maximal Exercise Capacity, Submaximal Exercise Capacity, Hemodynamic Parameters, Muscle Strength, Muscle Oxygenation, Vascular Function
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Cardiorespiratory Fitness
Step, Walk, Bike: Comparisons of Fitness Assessments
To compare cardiorespiratory fitness parameters (oxygen consumption and respiratory ventilation) measured during two sub-maximal exercise tests (six minute step test, 6MST \& six minute walk test, 6 MWT) with maximal exercise…
- Trial name
- NCT04830306
- Testing
- Exercise
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Duke University