Clinical trials: Mechanical Hypersensitivity
Migraine
Migraine is Associated With Altered Mechanical Pain Sensitivity. This Study Investigates Mechanical Pain Sensitivity, Headache Burden, and Quality of Life in Episodic and Chronic Migraine, Comparing Pressure Algometry and Algopeg® and Assessing Mechanosensitivity of Peripheral Nerves.
Migraine is one of the most prevalent neurological disorders and is associated with a substantial individual and societal burden.
- Trial name
- MechSens_Migra (NCT07559565)
- Testing
- pressure pain algometry
- Where
- Austria
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Bernhard Taxer
Asthma
Mechanical Heat Recovery Ventilation on House Dust Mite Sensitive Asthma
Asthma has become increasingly common in the UK, demanding our consideration of the cause. Many patients with asthma are allergic to house dust mites, which thrive in modern housing.
- Trial name
- NCT00148096
- Testing
- Mechanical Heat Recovery Ventilation
- Where
- United Kingdom
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Asthma, Cough
Bronchodilating and Bronchoprotective Effects of Deep Inspirations
The objectives of this research are to compare (i) the bronchodilating and (ii) the bronchoprotective effects of deep inspirations (DIs) in individuals with: (a) asthma, (b) CVA, (c) methacholine-induced cough but normal airway…
- Trial name
- NCT01659476
- Testing
- Methacholine(MCh) Challenge Testing
- Where
- Canada
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Queen's University
Asthma, Cough
Sensory-Mechanical Responses to Eucapneic Voluntary Hyperventilation and Mannitol
The objectives of this study are to determine the sensory-mechanical responses to Eucapneic Voluntary Hyperventilation (EVH) and Mannitol in individuals with cough variant asthma (CVA) and methacholine-induced cough with normal…
- Conditions
- Asthma, Cough, Cough Variant Asthma
- Trial name
- NCT03105843
- Testing
- Methacholine (MCh) Challenge Testing, Eucapneic Voluntary Hyperventilation (EVH), Mannitol Inhalation Kit
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Dr. Diane Lougheed
Healthy
Effect of Spinal Ketorolac After Acute Opioid Exposure
This research study is being done because pain is a significant problem for patients with a variety of medical problems and following surgery or traumatic injury.
- Trial name
- NCT00693160
- Testing
- ketorolac, remifentanil, Capsaicin
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Osteoarthritis, Pain
Efficacy of Etoricoxib 60 mg in Modifying Pain Hypersensitivity in People With Knee Osteoarthritis
This study aims to better understand the way in which painful osteoarthritis affects different people and whether an anti-inflammatory medication such as Arcoxia (etoricoxib) can help to modify this pain.
- Trial name
- NCT00927004
- Testing
- Etoricoxib (Arcoxia), Sugar pill
- Where
- Australia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Curtin University
Ventilator-Induced Diaphragmatic Dysfunction
Therapeutically Alternatives In Ventilator-Induced Diaphragm Dysfunction Critically Ill Patients
The study is a prospective experimental study on adult patients admitted to the Critical Care Department in Qasr Al-Ainy. This study is conducted prospectively to assess the efficiency of trigger sensitivity adjustment on…
- Trial name
- NCT06515600
- Testing
- Practice flow trigger sensitivity adjustment on mechanical ventilation for 1 week twice daily in addition to their plan of treatment.
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- South Valley University
Post Endodontic Pain, Mechanical Detection Threshold
The Effects of Preemptive Multimodal Analgesic on Endodontic Pain Following Root Canal Therapy.
A clinical trial comparing preemptive multimodal analgesics with placebo in the management of immediate and chronic post-endodontic pain.
- Conditions
- Post Endodontic Pain, Mechanical Detection Threshold, Mechanical Pain Threshold, Mechanical Pain Sensitivity
- Trial name
- NCT07400471
- Testing
- Pregabalin- Acetaminophen, Duloxetine- Acetaminophen
- Where
- Bangladesh
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Chattogram International Dental College