Clinical trials: Mechanical Ventilation Complication
Postoperative Pulmonary Complications, Impaired Oxygenation
PEEP Strategies and Mechanical Power in Robotic Surgery
Robotic surgery requires pneumoperitoneum and steep Trendelenburg positioning, which significantly impair respiratory mechanics and increase the risk of postoperative pulmonary complications.
- Conditions
- Postoperative Pulmonary Complications, Impaired Oxygenation, Mechanical Ventilation
- Trial name
- NCT07536464
- Testing
- Fixed PEEP Ventilation, Decremental PEEP Strategy, Incremental PEEP Strategy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Thoracic Neoplasm, Liver Cancer
Mechanically-assisted Ventilation in the Treatment of Moving Tumours With Photon and Proton Therapies
Mechanical ventilation can be used to impose a completely regular pattern of breathing frequency and inflation volume on the patient for as long as required.
- Conditions
- Thoracic Neoplasm, Liver Cancer, Ventilator Lung, Radiotherapy; Complications
- Trial name
- NCT03226925
- Testing
- Non-invasive mechanically-assisted ventilation, Dynamic MRI acquisition, Planning 4D-CT
- Where
- Belgium
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Congenital Heart Disease, Mechanical Ventilation Complication
Mechanical Ventilation During Cardiopulmonary Bypass
The study is about a protocol of protective mechanical ventilation during cardiopulmonary bypass used during cardiosurgery for the correction of congenital heart diseases, to evaluate what's the best for the lungs
- Conditions
- Congenital Heart Disease, Mechanical Ventilation Complication, Cardiopulmonary Bypass
- Trial name
- VENICE (NCT03629574)
- Testing
- Ventilation during cardiopulmonary bypass
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera di Padova
Ventilator Associated Pneumonia, Tracheobronchitis
Effect of Chlorhexidine-Induced Oral Care on Ventilator-Related Some Respiratory System Complications
Ventilator-associated pneumonia and ventilator-associated treakeabronchitis in respiratory tract infections associated with ventilator are common infections in intensive care unit and cause significant morbidity, mortality and…
- Trial name
- NCT04505202
- Testing
- 0.12% chlorhexidine gluconate
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Intensive Care Unit Acquired Weakness, Intensive Care Unit Delirium
Efficacy of the "Start to Move" Protocol on Functionality, Delirium and Acquired Weakness in ICU
Background: ICU hospitalization is associated with loss of strength, functionality and delirium. The "Start to Move protocol" demonstrated efficacy in improving and minimizing such effects.
- Conditions
- Intensive Care Unit Acquired Weakness, Intensive Care Unit Delirium, Intensive Care Neuropathy, Intensive Care Unit Syndrome
- Trial name
- STM (NCT05053724)
- Testing
- Star to move Protocol
- Where
- Chile
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Hospital Felix Bulnes
Infant, Newborn, Diseases, Intubation Complication
Noninvasive Positive Pressure Ventilation During Neonatal Nasal Intubation
The goal of this study is to perform a quality control assessment of our local intubation protocol in any newborn infant requiring endotracheal intubation in the delivery room or neonatal intensive care unit at the Department of…
- Trial name
- IntubAID (NCT06139809)
- Testing
- Intubation
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Mechanical Ventilation Complication
Impact of Inspiratory Muscle Pressure Curves on the Ability of Professionals to Identify Patient-ventilator Asynchronies
Patient-ventilator asynchronies can occur as a result of a mismatch between neural (patient) and ventilator inspiratory and expiratory phases.
- Trial name
- Pmus (NCT05144607)
- Testing
- Muscle Pressure curve (Pmus)
- Where
- Brazil
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Hospital Sirio-Libanes
Cardio Respiratory Arrest, Cardiac Death
Ventilation in Cardiac Arrest
Over the last decades, research in cardiopulmonary resuscitation was primarily focused on uninterrupted chest compressions to restore sufficient circulation.
- Conditions
- Cardio Respiratory Arrest, Cardiac Death, Ventilation Therapy; Complications, Apnea
- Trial name
- VICA (NCT04657393)
- Testing
- mechanical ventilation
- Where
- Austria
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Mechanical Ventilation Complication, Pneumonia
Mechanically Ventilated Children and Pacifiers
Mechanical ventilation is a life support system developed to support or restore normal lung functions. Children who are connected to mechanical ventilator, separation from family in intensive care environment, getting away from…
- Conditions
- Mechanical Ventilation Complication, Pneumonia, Bronchiolitis
- Trial name
- NCT05566184
- Testing
- Modified pacifier
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hitit University
Mechanical Ventilation Complication, Vascular Injury
Vascular Injury in Mechanical Ventilation: a Proof-of-Concept Study
Investigation of the effect of mechanical ventilation on biomarkers of microvascular damage
- Conditions
- Mechanical Ventilation Complication, Vascular Injury, Endothelial Dysfunction
- Trial name
- NCT05538858
- Testing
- Mechanical Ventilation
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Respiratory Insufficiency, Ventilation Therapy; Complications
KAP Asynchrony Survey
The investigators developed a web-based survey to assess knowledge, attitudes and practice of health care professionals about patient-ventilator asynchrony.
- Conditions
- Respiratory Insufficiency, Ventilation Therapy; Complications, Ventilators, Mechanical, Respiration, Artificial
- Trial name
- KAPA (NCT03439683)
- Testing
- Survey about patient-ventilator asynchrony
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Left Ventricular Diastolic Dysfunction, Weaning Failure
Left Ventricular Diastolic Dysfunction as a Predictor of Weaning Failure From Mechanical Ventilation
Both premature and delayed extubation prolong the duration of mechanical ventilation and the intensive care unit (ICU) length of stay and increase morbidity and mortality.
- Conditions
- Left Ventricular Diastolic Dysfunction, Weaning Failure, Mechanical Ventilation Complication, Diaphragmatic Disorder
- Trial name
- NCT04703387
- Testing
- transthoracic echocardiography
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Tanta University
Mechanical Ventilation Complication, Aediatric Anesthesia
Mechanical Power in Pediatric Mechanical Ventilation
Mechanical power is the amount of energy transferred to the respiratory system of patients during each breath period. After overcoming the resistances required for respiration, the remaining energy may end up by damaging the lung…
- Trial name
- NCT05127317
- Testing
- Mechanical power
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Bozok University
Ventilation Therapy; Complications
Diaphragmatic Mobility In Ventilated Assisted Patients
The study was a randomized controlled trial. A total of 24 patients who met the inclusion criteria were included in this study and randomly divided by sealed envelope method into Experimental and Control groups with 12 patients…
- Trial name
- NCT04733261
- Testing
- Diaphragmatic mobility, Chest Physiotherapy
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Aqua Medical Services (Pvt) Ltd
Mechanical Ventilation Complication, Respiratory Distress Syndrome in Premature Infant
Effect of Implementing Evidence Based Practices on Prevention of Associated Nasal Pressure Injuries Among Preterm Neonates With Non-Invasive Respiratory Support
This study aims to evaluate the effect of implementing evidence based practices on prevention of associated nasal pressure injuries among preterm neonates with non invasive respiratory support
- Trial name
- NCT06642285
- Testing
- Non Invasive Respiratory Support bundle
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Postoperative Atelectasis, Postoperative Pulmonary Atelectasis
Lung Ultrasound Assessment of Postoperative Atelectasis After Mechanical Ventilation With Minimum Driving Pressure
Brief summary The goal of this clinical trial is to compare two different types of perioperative mechanical ventilation (MV), specifically Protective Mechanical Ventilation (PMV) and MV with the lowest possible Driving Pressure…
- Conditions
- Postoperative Atelectasis, Postoperative Pulmonary Atelectasis, Postoperative Pulmonary Complications (PPCs), Lung Ultrasonography Score
- Trial name
- NCT07186920
- Testing
- PEEP titration for Minimum Driving Pressure, Lung Protective Ventilation
- Where
- Greece
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University General Hospital of Patras
Deglutition Disorders, Tracheostomy Complication
Deflating the Tracheostomy Tube Cuff and Time for Decannulation
Introduction: Inpatients in an intensive care unit can need tracheostomy. To start the tracheostomy decannulation process, one of the procedures is to deflate the cuff.
- Trial name
- NCT05395728
- Testing
- Deflate the tracheostomy cuff early, Deflate the tracheostomy cuff after complete weaning mechanical ventilation
- Where
- Brazil
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Hospital Moinhos de Vento
Epidural Analgesia, Mechanical Ventilation
Effects of Thoracic Epidural Analgesia in Geriatric Patients Undergoing Open Heart Surgery
Elderly patients have a higher incidence of morbidity and mortality due to the interaction of various factors such as decreased physiological reserves, concomitant comorbidities, multiple drug use, cognitive dysfunction, and…
- Conditions
- Epidural Analgesia, Mechanical Ventilation, Postoperative Complications, Analgesia
- Trial name
- NCT04708080
- Testing
- thoracic epidural analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Injury of Diaphragm, Mechanical Ventilation Complication
Using Ultrasound to Study Respiratory Muscle Function in Critically Ill Patients
Mechanical ventilation can be life saving strategy for patients with respiratory failure due to a variety of reasons. Once the underlying illness has resolved, intensive care doctors have to take a decision on when the patient is…
- Conditions
- Injury of Diaphragm, Mechanical Ventilation Complication, Critical Illness
- Trial name
- NCT03139695
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Anesthesia, Perioperative/Postoperative Complications
Use of Heart-lung Interaction to Predict Haemodynamic Tolerance to the Open Lung Approach With Individualised PEEP
This is an observational, prospective, single-centre study that will focus on patients undergoing major non-cardiac surgery requiring invasive mechanical ventilation and invasive blood pressure monitoring Hypotheses: A positive…
- Conditions
- Anesthesia, Perioperative/Postoperative Complications, Hypovolemia, Haemodynamic Instability
- Trial name
- HiPEEP (NCT06123039)
- Testing
- Tidal Volume Challenge, Recruitment maneuver obtaining individualised PEEP
- Where
- Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Fe