Clinical trials: Medial Knee Compartment Arthritis
Knee Osteoarthritis
Management of Combined Patellofemoral and Medial Compartment Knee Osteoarthritis
Evaluate the results of management of patients with patellofemoral and medial compartment knee osteoarthritis with open wedge high tibial osteotomy with or without arthroscopic partial lateral patellar facetectomy
- Trial name
- NCT06762171
- Testing
- open wedge high tibial osteotomy, Arthroscopic partial lateral patellar facetectomy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sohag University
Osteoarthritis, Knee
Optimum Radiographic Assessment of the Knee
X-rays are the most frequently used imaging test when evaluating the knee for joint replacement. They are non-invasive, safe and cost effective.
- Trial name
- NCT03685019
- Testing
- Valgus Stress, Varus stress, 0 degree flexion radiograph
- Volunteers
- 8 people
- Sponsor
- Oxford University Hospitals NHS Trust
Arthroplasty, Replacement, Knee, Unicompartmental Knee Arthroplasty
Study to Evaluate Patient Outcomes and Safety and Effectiveness of Robotic Assisted Unicompartmental Knee Replacements Versus Conventional Unicompartmental Knee for Subjects With Primary Arthritis of the Knee Joint Involving One (UKA) Compartment (Medial or Lateral)
The overall aim of this trial is to compare functional and patient-reported outcomes and to assess the safety and effectiveness and long-term performance of the Smith+Nephew Robotic Systems for Unicompartmental Knee Replacements…
- Trial name
- NCT06036212
- Testing
- Robotic System, Conventional
- Where
- 5 sites in United Kingdom
- Sponsor
- Smith & Nephew, Inc.
Knee Osteoarthritis, Medial Compartment Knee Osteoarthritis
A Study Evaluating the Safety, Efficacy, and Pharmacodynamic Effects of ABT-981 in Patients With Knee Osteoarthritis
A Phase 2a, multicenter, randomized, double-blind, parallel group, placebo-controlled study to evaluate the safety, tolerability, efficacy and pharmacokinetic/pharmacodynamic effect of ABT-981 in patients with symptomatic…
- Trial name
- NCT02087904
- Testing
- ABT-981
- Volunteers
- 350 people
- Sponsor
- AbbVie
Medial Compartment Knee Osteoarthritis
Effectiveness of Lateral Wedge Insole on Knee Osteoarthritis Outcomes in Pakistani Population
Osteoarthritis (OA) is a persistent joint disorder, which normally affects the weight bearing joints especially knee joint. Lateral wedge insole is one such approach suggested by professionals to manage the knee…
- Trial name
- NCT05104008
- Testing
- Lateral wedge insoles with home exercises group(Group 1), Traditional physiotherapy with home exercises group (Group 2)
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Isra University
Medial Compartment Osteoarthritis of the Knee
HTO With and Without Arthroscopy
It remains unknown if a concomitant arthroscopic knee debridement would increase the benefits of surgery (quality of life and functional ability) for young active patients with medial compartment OA of the knee and varus…
- Trial name
- NCT00284622
- Testing
- Arthroscopy
- Where
- Canada
- Volunteers
- 98 people
- Sponsor
- Fowler Kennedy Sport Medicine Clinic
Osteoarthritis
A Clinical Investigation of the Oxford® Partial Knee System
The purpose of this prospective data collection is to document the performance and clinical outcomes of the Oxford® Partial Knee System.
- Trial name
- NCT00699257
- Volunteers
- 85 people
- Sponsor
- Biomet Orthopedics, LLC
Medial Knee Compartment Arthritis
Oxford Partial Knee Kinematics Gait Analysis Study
The objective of this study is to compare the effect on gait of unicompartmental knee arthroplasty (UKA), using the Oxford Partial Knee, versus normal knee.
- Trial name
- NCT01454908
- Testing
- Oxford Partial Knee
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The CORE Institute
Osteo Arthritis Knee, Arthritis Knee
Total Versus Robotic Assisted Unicompartmental Knee Replacement
The purpose of this research is to compare the functional outcomes of patients with end stage medial compartment OA of the knee undergoing a conventional mTKA to those undergoing rUKA and to assess the associated cost economics…
- Conditions
- Osteo Arthritis Knee, Arthritis Knee, Arthropathy of Knee
- Trial name
- TRAKER (NCT05290818)
- Testing
- MAKO™ Partial Knee Arthroplasty, Triathlon (Stryker) Total Knee Arthroplasty
- Where
- United Kingdom
- Volunteers
- 159 people
- Sponsor
- NHS Lothian
Knee Osteoarthritis
Effects of Textured Insoles on Balance, Physical Performance, and Plantar Pressure in Older Adults With Knee Osteoarthritis
This study aims to investigate the effects of textured insoles on balance, physical performance, and plantar pressure distribution in older adults with medial compartment knee osteoarthritis.
- Trial name
- TIKOA (NCT07097649)
- Testing
- Textured lateral wedge insole, Use of lateral wedge flat insole
- Volunteers
- 44 people
- Sponsor
- Esra Nur Turkmen
Osteoarthritis of the Knee
Efficacy Study of an Unloading Brace for Knee Osteoarthritis
Subjects with symptomatic unicompartmental osteoarthritis of the knee will be invited to participate in this randomized study. Subjects will be assigned to either a Fusion Osteoarthritis Knee Brace group, or a control group that…
- Trial name
- NCT02150057
- Testing
- Breg Fusion Unloading Brace
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Andrews Research & Education Foundation
Knee Osteoarthritis
Lower Knee Joint Loading by Real-time Biofeedback Stair Walking Rehabilitation for Patients With MCKOA
This study will establish a machine-learning algorithm to predict KAM using IMU sensors during stair ascent and descent; and then conduct a three-arm randomized controlled trial to compare the biomechanical and clinical…
- Trial name
- NCT03734380
- Testing
- Laboratory-based gait retraining (LGR), Sensor-based gait retraining (SGR), Walking exercise control (Ctrl)
- Where
- China
- Volunteers
- 57 people
- Sponsor
- The Hong Kong Polytechnic University
Osteoarthritis, Knee
The Inclination of the Proximal Tibiofibular Joint Surface and Medial Compartment Knee Osteoarthritis
This study aims to research on the association between the inclination of the proximal tibiofibular joint surface and medial compartment knee osteoarthritis.
- Trial name
- NCT03147495
- Testing
- Standing anteroposterior knee radiographs and special proximal tibiofibular joint radiograph.
- Where
- China
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- 113th Hospital of Chinese People's Liberation Army
Osteoarthritis, Knee
Unicompartmental Versus Total Knee Replacement for Medial Compartment Knee Osteoarthritis
For patients with osteoarthritis affecting only the inner part of the knee, surgeons can offer either a partial knee replacement, which resurfaces the worn compartment alone, or a total knee replacement.
- Conditions
- Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
- Trial name
- FLEX-UNI (NCT04913987)
- Testing
- Persona Partial Knee (PPK), Triathlon cruciate-retaining total knee system.
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Golden Jubilee National Hospital
Medial Compartment Osteoarthritis of the Knee
Effects of Osteotomies Around the Knee on Cartilage Glycosaminoglycan Content Using dGEMRIC Non-invasive Imaging
Medial compartment osteoarthritis of the knee is commonly treated by a surgical intervention called 'high tibial osteotomy' (VTO).
- Trial name
- NCT01269944
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- UMC Utrecht
Medial Compartment Knee Osteoarthritis
The Effect of a Novel Joint Distraction Knee Orthosis for Treating Medial Knee Osteoarthritis
The Effect of a Novel Joint Distraction Knee Orthosis for Treating Medial Knee Osteoarthritis
- Trial name
- NCT07439315
- Testing
- Medial joint distraction brace
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Icarus Medical Innovations
Medial Compartment Knee Osteoarthritis
Effects of Lateral Wedge Insoles, Knee Taping on the Management of Knee Osteoarthritis
Knee osteoarthritis (OA) is a degenerative, progressive and wide spread disease, which may lead the patient to severe outcomes e.g. pain, loss of joint motion, inflexibility, disability and decreases the quality of life (QOL).
- Trial name
- NCT03848130
- Testing
- Mulligan Knee Taping with Home Exercises, Lateral wedge insoles with Home Exercises, Traditional Physiotherapy with Home Exercises
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Isra University
Osteo Arthritis Knee
Trial of Unicompartmental Versus Total Knee Arthroplasty
This study is a prospective, randomized trial to compare patient outcomes of unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) for the treatment of medial compartment osteoarthritis.
- Trial name
- NCT03385759
- Testing
- Unicompartmental knee arthroplasty, Total knee arthroplasty
- Where
- 2 sites in United States
- Volunteers
- 112 people
- Sponsor
- Anderson Orthopaedic Research Institute
Knee Osteoarthritis (Mild to Moderate, Medial Compartment)
Enhancing Medial Knee Pain Rehabilitation : A Clinical Trial On The Effectiveness Of Blood Flow Restriction In Combination With Targeted Exercises For Adult With Varus Deformity
Medial knee pain is common in active adults with varus knee alignment and can limit daily and sports activities. Standard physiotherapy can reduce pain and improve function, but strength gains may be suboptimal when patients…
- Trial name
- NCT07283237
- Testing
- Targeted Exercise Program, Blood Flow Restriction (BFR) Training with Targeted Exercise Program
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Knee Osteoarthritis
Effect of Knee Bracing on Improving Pain & Disability
The overall purpose of the proposed pilot study is to establish the feasibility of conducting a clinical trial by evaluating the preliminary effects of 8 weeks of knee bracing on physiological measures of self-reported pain and…
- Trial name
- NCT04044612
- Testing
- Medial Unloader Brace
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of North Carolina, Chapel Hill