Clinical trials: Medical Abortion
Second Trimester Medical Abortion
Paracervical Block During II-trimester Abortion
Paracervical blockage can reduce severe pain during second trimester induced medical abortion.
- Trial name
- NCT01617564
- Testing
- bipuvacain, NaCl
- Where
- 2 sites in Sweden
- Volunteers
- 112 people
- Sponsor
- Kristina Gemzell Danielsson
Medical Abortion
Simplifying Menstrual Regulation (MR): Post Abortion Care in Pakistan
This study is an additional component of protocol 6005, titled Simplifying Menstrual Regulation (MR): Exploring the role of at-home semi-quantitative pregnancy tests for follow-up to menstrual regulation service provision in…
- Trial name
- NCT02343913
- Testing
- PAC checklist
- Where
- 15 sites in Pakistan
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical; Abortion, Fetus
Comparison of Telephone Follow-up With In-person Follow-up After Medical Abortion
Background: Medical abortions in Canada are provided using a standard regimen of methotrexate and misoprostol. After these medications are administered, patients are most commonly checked for termination of the pregnancy with an…
- Trial name
- NCT01943279
- Testing
- Remote Follow-up (RFU), Standard Follow-up (SFU)
- Where
- 2 sites in Canada
- Volunteers
- 139 people
- Sponsor
- Women's College Hospital
Abortion; Attempted, Medical
Feasibility of a Self-performed Urinary Test for the Follow-up on Medical Abortion
This study was a national, longitudinal, prospective, observational survey, carried out in metropolitan France, with a sampling of 21 birth control centres.
- Trial name
- NCT02304835
- Where
- France
- Volunteers
- 322 people
- Sponsor
- Nordic Pharma SAS
Medical Abortion
Effectiveness of Pregnancy Tests as an Assessment Tool to Identify Continuing Pregnancy
This randomized study will examine the effectiveness of two types of pregnancy tests (a semi-quantitative test and a high sensitivity test) to identify continuing pregnancy at home at various time points after early medical…
- Trial name
- NCT01856777
- Testing
- Semi-quantitative panel test, High sensitivity urine pregnancy test
- Where
- 2 sites in Vietnam
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical; Abortion, Fetus
Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Termination of Pregnancy Analgesia
This study included women who underwent voluntary second trimester termination of pregnancy. Patients were randomized to programmed intermittent epidural anesthetic bolus or continuous epidural infusion for pain analgesia.
- Trial name
- NCT01860521
- Testing
- Programmed Intermittent Epidural Bolus, Continuous Epidural Infusion, Procedure of interruption of pregnancy
- Where
- Italy
- Volunteers
- 104 people
- Sponsor
- IRCCS Azienda Ospedaliera Universitaria San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
Medical; Abortion, Fetus
Mifepristone and Misoprostol for the Termination of Pregnancy up to 70 Days Gestation
The purpose of this study is to determine the efficacy and acceptability of a regimen of 200 mg mifepristone (Zacafemyl), followed 24-48 hours later by 800 mcg of buccal misoprostol.
- Trial name
- NCT01966874
- Where
- United States
- Volunteers
- 1,001 people
- Sponsor
- Gynuity Health Projects
Medical Abortion
Acceptability of an Out-patient Regimen of Medical Abortion With Mifepristone and 800 Mcg Misoprostol Administered at 78-84 Days Gestation
These pilot studies are designed as open label studies to investigate the acceptability of 200 mg mifepristone followed 24-48 hours later by either 1) 800 µg misoprostol administered buccally or 2) 800 µg misoprostol administered…
- Trial name
- NCT01856985
- Testing
- Misoprostol, Mifepristone
- Where
- Vietnam
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical Abortion
Safety and Efficacy of Medical Abortion Provided by Midlevel Providers or Physicians
The physical examination before an abortion is usually performed by a physician. However, in many countries access to physicians is limited.
- Trial name
- NCT01612923
- Testing
- Midwife
- Where
- Sweden
- Volunteers
- 1,180 people
- Sponsor
- Kristina Gemzell Danielsson
Medical Abortion
Routine Follow-up Versus Self-assessment in Medical Abortion
The main objective of the study is to optimize the routines for follow-up after medical abortion in order to give women more autonomy by reducing the number of consultations involved and to reduce the frequency of postabortal…
- Trial name
- NCT01487213
- Testing
- Home self assessment of complete medical abortion
- Where
- 4 sites in Austria, Finland and 2 more
- Volunteers
- 929 people
- Sponsor
- Karolinska Institutet
Medical Abortion, Fetus
Reducing the Need for In-Clinic Follow-Up for Medical Abortion in Moldova and Uzbekistan
The purpose of this study is to determine whether an alternative method of follow-up after medical abortion is acceptable and feasible for use in Moldova and Uzbekistan.
- Trial name
- NCT01410266
- Testing
- Alternative follow-up
- Where
- 7 sites in Moldova, Uzbekistan
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical Abortion
The Extended Gestational Age Medical Abortion Study
This open-label, comparative study will compare the efficacy, safety, and acceptability of 200 mg mifepristone followed in 24-48 hours by 800mcg buccal misoprostol or 400mcg sublingual misoprostol for termination of pregnancy in…
- Trial name
- NCT00997347
- Testing
- Mifepristone and misoprostol
- Where
- 12 sites in United States, Georgia and 3 more
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical Abortion
Does Follow-up With Serum Beta Human Chorionic Gonadotropin (BhCG) Simplify Medical Abortion?
The purpose of this study is to evaluate if BhCG testing to determine the completion of medical abortion simplifies the medical abortion protocol.
- Trial name
- NCT00907725
- Testing
- serum BhCG follow-up, ultrasonographic follow-up
- Where
- United States
- Volunteers
- 376 people
- Sponsor
- Planned Parenthood League of Massachusetts
IUC Insertion After Medical Abortion
Intrauterine Contraception (IUC) After Medical Abortion
Today a large proportion of early abortions are medical, in accordance to the woman's choice. The main objective of the present study was to compare, in a randomised fashion, initiation of intrauterine contraception (IUC) at…
- Trial name
- NCT01537562
- Testing
- Timing of IUC insertion
- Where
- Sweden
- Volunteers
- 129 people
- Sponsor
- Karolinska Institutet
Intrauterine Device Expulsion, Medical Abortion
Insertion of an Intrauterine Device (IUD) After Medical Abortion
The purpose of this study is to determine the expulsion and continuation rate of an intruterine device (IUD) placed immediately after medical abortion.
- Conditions
- Intrauterine Device Expulsion, Medical Abortion, Induced Abortion
- Trial name
- NCT00621543
- Testing
- IUD insertion [Copper T-380A or Levonorgestrel (intrauterine system) IUS]
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- Boston University
Medical Abortion
Treatment Regimens for Mifegyne and Cytotec
The purpose of this study is to test two regimens of mifegyne and cytotec for medical abortion. The investigators hypothesize that administration of both medications during one hospital visit will not compromise effectiveness.
- Trial name
- NCT00920465
- Testing
- mifegyne and cytotec
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Western Galilee Hospital-Nahariya
Medical Abortion
The Acceptability and Feasibility of an Alternative to Routine Follow-up Visit After Medical Abortion in Vietnam
This trial will compare the efficacy and acceptability of post-medical abortion follow-up by assigning women to either 1) alternative follow-up via routine semi-quantitative pregnancy test and a self-administered follow-up…
- Trial name
- NCT01150422
- Testing
- Alternative follow-up
- Where
- 4 sites in Vietnam
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical Abortion
Comparison of the Safety and Efficacy of Medical Abortion Provided by Physicians and Midlevel Providers in Nepal
The purpose of the study is to compare the safety, effectiveness, and acceptability of medical abortion provided by doctors and midlevel providers in a developing country where doctors are scarce, such as Nepal.
- Trial name
- NCT01186302
- Testing
- Type of provider
- Where
- Nepal
- Volunteers
- 1,104 people
- Sponsor
- World Health Organization
Medical Abortion
Determining Women's Preferences for Medical Abortion Using Willingness to Pay
New medical abortion regimens are being tested with increasing frequency. However women's preferences for certain attributes of the regimes are not being investigated to any great degree.
- Trial name
- NCT00472394
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Medical Abortion
De-Medicalizing Mifepristone Medical Abortion
This study will investigate the possibility that medical abortion using mifepristone and misoprostol - a safe, proven therapy for terminating early first trimester pregnancy - can be administered in a manner that is simpler and…
- Trial name
- NCT00120224
- Where
- 3 sites in United States
- Volunteers
- 4,410 people
- Sponsor
- Gynuity Health Projects