Clinical trials: Medical Adherence
Tyrosinemias, Alkaptonuria
Evaluation of TYR Sphere
For 28 days, 20 patients with tyrosinaemia will take TYR sphere as part of the usual dietary management of their condition. Patients will record their adherence to recommended intakes each day, gastrointestinal symptoms (if any)…
- Conditions
- Tyrosinemias, Alkaptonuria, Tyrosinemia, Type I, Tyrosinemia, Type II
- Trial name
- NCT04196959
- Testing
- TYR sphere
- Where
- 2 sites in United Kingdom
- Volunteers
- 18 people
- Sponsor
- Vitaflo International, Ltd
Influenza, Infections, Pneumococcal
System Alignment for VaccinE Delivery (SAVED): Improving Rates of Influenza and Pneumococcal Vaccination Through Patient Outreach, Improved Medical Record Accuracy and Targeted Physician Alerts
The goal of this research study is to improve rates of appropriate influenza and pneumococcal vaccination among adults who receive care at a large multi-specialty group practice in central Massachusetts.
- Trial name
- NCT02266277
- Testing
- Arm 1: E-portal message with IVR call, Arm 2: E-portal message with no IVR call, Arm 3: No e-portal message with IVR call
- Where
- United States
- Volunteers
- 30,000 people
- Sponsor
- University of Massachusetts, Worcester
Utilization, Health Care, Engagement, Patient
Home Visits for Patients at Risk for Appointment No-shows
Unused clinic visits due to patient no-shows continue to plague American healthcare as a large source of waste and avoidable constraint on access.
- Conditions
- Utilization, Health Care, Engagement, Patient, No-Show Patients
- Trial name
- SNAP HOME (NCT04376736)
- Testing
- Home visit
- Where
- United States
- Sponsor
- Johns Hopkins University
Sleep Deprivation, Depression
Work Hour Reductions, Medical Errors, and Intern Well-Being at Providence St. Vincent Medical Center Intensive Care Unit
The purpose of this study is to determine whether reducing intern work hours and eliminating extended shifts in the intensive care unit will reduce prescribing errors and improve intern well-being.
- Trial name
- NCT00996320
- Testing
- Reduced work hour schedule
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Providence Health & Services
Fatigue, Sleep Deprivation
Effect and Utilization of Protected Time Among Interns on Extended Duty-Hour Call Shifts
This study will test the feasibility and effectiveness of protected time for physicians in training during 30 hour shifts in a medical intensive care unit. The primary outcome will be fatigue.
- Conditions
- Fatigue, Sleep Deprivation, Depression
- Trial name
- NCT00983008
- Testing
- Protected time and Dedicated time
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Providence Health & Services
Nausea, Pain
Prophylactic Analgesic and Antiemetic Regimen for Medical Abortion < 70 Days
Randomized trial which will aim to evaluate whether prophylactic use of ondansetron and ibuprofen will decrease side effects associated with medical abortion and increase patient satisfaction.
- Trial name
- NCT05819619
- Testing
- Prophylactic use of ibuprofen and ondansetron post misoprostol administration, Use of ibuprofen and ondansetron at symptom onset post misoprostol administration
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Hackensack Meridian Health
Patient Satisfaction, Conventional Magnetic Resonance Imaging
Portable Rapid Imaging for Medical Emergencies
This study will compare the time it takes to scan a patient in the emergency department with a portable MRI when compared to a conventional MRI.
- Conditions
- Patient Satisfaction, Conventional Magnetic Resonance Imaging, Portable Magnetic Resonance Imaging
- Trial name
- PRIME (NCT06930534)
- Testing
- Swoop Plus Mk2.0
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Apnea Syndrome, Apnea, Obstructive
Effect of Hypnosis on Adherence to Continuous Positive Airway Pressure.
The prevalence of sleep-disordered breathing is high, with an apnea-hypopnea index of over 15 per hour found in 49.7% of men and 23.4% of women in the general population (1).
- Trial name
- HypnOSA (NCT06397365)
- Testing
- medical hypnosis
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Solelhac Geoffroy
Bone Tumor, Bone Cancer
Medical Payment Case Management for Financial Toxicity in Patients With Primary Bone Tumors: A Randomized Controlled Trial
The goal of this clinical trial is to learn if adding a medical payment case management service to the hospital's usual follow-up care can reduce the financial hardship of cancer treatment in patients of any age, including…
- Trial name
- NCT07888244
- Testing
- Medical payment case management service
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Shanghai 6th People's Hospital
Discrimination, Social, Health Care Utilization
Still Climbin': An Intervention to Improve Coping Among Black Sexual Minority Men
This study consists of a randomized controlled trial of a multi-session cognitive behavior therapy (CBT) group intervention that addresses coping with discrimination and medical mistrust among Black sexual minority men (SMM).
- Trial name
- NCT04587869
- Testing
- CBT Coping Intervention
- Where
- United States
- Volunteers
- 369 people, healthy volunteers welcome
- Sponsor
- RAND
HIV
City-Wide Implementation and Evaluation of the B-OK Bottles for HIV Treatment Adherence Support in the Philadelphia Ryan White Medical Case Management Network
The researchers will conduct a hybrid implementation-effectiveness study of a city-wide B-OK rollout led by PDPH with research and evaluation support from the University of Pennsylvania.
- Trial name
- B-OK PDPH (NCT07807137)
- Testing
- B-OK Bead Bottles
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Pediatrics, Medically Complex
Parental Adherence of a Mobile Application
This is a single-site, stratified grouping parallel- randomized control trial design comparing 30-day all-cause readmission rates and parent experience with two groups of pediatric participants.
- Conditions
- Pediatrics, Medically Complex, Children With Medical Complexity (CMC), Nursing
- Trial name
- PARAMETER (NCT06672042)
- Testing
- CHAMP App
- Where
- United States
- Sponsor
- Children's Mercy Hospital Kansas City
Heart Failure
Guideline Directed Medical Therapy (GDMT) Optimization and Adherence Longitudinal Study for Heart Failure.
A multicenter, non-randomized prospective longitudinal study to evaluate the feasibility of Tricog's Remote platform for Guideline Directed Medical Therapy (GDMT) titration and remote patient monitoring among patients with Heart…
- Trial name
- GOALS-HF (NCT05906745)
- Where
- 4 sites in United States, India
- Volunteers
- 52 people
- Sponsor
- Tricog Health Inc
Bacterial Infections, Acute Bacterial Skin and Skin Structure Infection
Development of a New Critical Pathway for Treatment of Acute Bacterial Skin and Skin Structure Infections (ABSSSI)
The purpose of this study is to assess the effect of a new critical pathway (use of guideline-based patient identification criteria and for those who meet these criteria, use of dalbavancin) compared to usual care for the…
- Trial name
- NCT03233438
- Testing
- Dalbavancin, Usual Care
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Allergan
Chronic Disease, Asthma
Feasibility of Ripple Health Smart Pill Caps in Clinical Settings
The purpose of this research is to determine whether Ripple Health Smart Medicine Bottle Caps can allow for better interface medication administration than traditional pill bottles.
- Trial name
- NCT05192928
- Testing
- Ripple Health Smart Pill Cap
- Where
- 4 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Manan Shukla
Pulmonary Arterial Hypertension
Exercise Intervention as an Adjunct to Medical Therapy in Newly Diagnosed Patients With Pulmonary Arterial Hypertension
The goal of this clinical trial is to learn if an exercise programme started shortly after diagnosis improves the fitness and mental wellbeing of patients with pulmonary hypertenion over and above medication alone.
- Trial name
- NCT07366879
- Testing
- Home-based, remotely delivered, supervised Exercise programme
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Golden Jubilee National Hospital
Heart Failure With Reduced Ejection Fraction
Email Nudges to Improve GDMT (MRA) Adherence in Heart Failure
The Email Nudges to Improve GDMT (MRA) Adherence in Heart Failure (ENIGMA-HF) study is a pragmatic parallel-arm randomized control trial of a quality improvement (QI) intervention involving email nudges to cardiology clinic…
- Trial name
- ENIGMA-HF (NCT05806970)
- Testing
- Email Nudge
- Where
- United States
- Sponsor
- University of California, Los Angeles
Maternal Behavior, Mobile Health
A Prospective Randomized Controlled Trial of Mobile Medical Used for Management of Pregnant Women
A multicenter, randomized controlled trial was conducted to investigate whether health education and life style management through WeChat group chat was: 1. more effective in improving pregnancy outcomes in normal pregnant women.
- Conditions
- Maternal Behavior, Mobile Health, Pregnancy Outcome, GDM
- Trial name
- NCT03748576
- Testing
- telemedicine: management through WeChat group chat
- Where
- China
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Program Engagement, Treatment Adherence and Compliance
Choice and Autonomy in Learning Mindfulness for Pediatric Residents
This study is a pilot clinical trial designed to evaluate a flexible, online mindfulness program for pediatric residents. Medical training can be stressful, and although mindfulness programs are often offered to support…
- Conditions
- Program Engagement, Treatment Adherence and Compliance, Mindfulness, Self-Compassion
- Trial name
- CALM-PR (NCT07542769)
- Testing
- Wakeful Digital Mindfulness Program
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Heart Failure
Evaluating Adherence to Guideline-Directed Medical Therapy in Patients With Advanced Heart Failure
A Prospective Observational, Multi-Center, Real-World Pharmacological Study Evaluating Adherence to Guideline-Directed Medical Therapy Using the Four-Pillar Strategy in Patients with Advanced Heart Failure
- Trial name
- ad-HUB (NCT07560982)
- Testing
- GDMT, Quality of life questionnaire
- Where
- 2 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Università Vita-Salute San Raffaele