Clinical trials: Medical Disorders
Opioid Dependence, Substance Abuse Disorders
The MOUD Plus Pilot: Counseling and Peer Support to Support Retention for Medically Complex Patients With Opioid Use Disorder Seen In Primary Care
The goal of this pilot clinical trial is to learn if a community informed designed program of addiction counseling with coordinated community peer navigator for people with Opioid Use Disorder (OUD) and other medical conditions…
- Conditions
- Opioid Dependence, Substance Abuse Disorders, Complex Medical Patients, Primary Care Patients With Chronic Conditions
- Trial name
- MOUD+ (NCT06837662)
- Testing
- MOUD "Plus" Intervention (treatment as usual + coordinated counseling and referral to community based peer), Treatment As Usual (primary care with low threshold MOUD prescribing)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Oregon Health and Science University
Effects of Classical and Heavy Metal Music on Stress, Anxiety, and Pulse Rate Among Medical Students
Classical and Heavy Metal Music Effects on Stress Among Medical Students
This study examined how listening to classical music compared with heavy metal music affected perceived stress, state anxiety, and pulse rate among medical students at the University of Sharjah.
- Trial name
- NCT07848503
- Testing
- Classical Music, Heavy Metal Music
- Where
- United Arab Emirates
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Medical Education, Clinical Competence
Emergency Structured Clinical Examination Training bOX
This study assessed whether a training toolbox called ECOX could help medical students prepare for their objective structured clinical examination (OSCE) during an emergency medicine clerkship.
- Conditions
- Medical Education, Clinical Competence, Examination-Related Anxiety
- Trial name
- ECOX (NCT06124430)
- Testing
- ECOX workplace-based training toolbox
- Where
- France
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Acceptance and Commitment Therapy, Child With Medical Complexity
Acceptance and Commitment Therapy-based Intervention for Parents of a Child With Medical Complexity
A pilot randomized controlled trial of an Acceptance and Commitment Therapy-based intervention will be conducted to decrease psychological symptoms, while increase psychological flexibility for parents of a child with medical…
- Conditions
- Acceptance and Commitment Therapy, Child With Medical Complexity, Psychological Flexibility, Randomised Controlled Trial
- Trial name
- NCT07033832
- Testing
- ACT-based intervention
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 24 people
- Sponsor
- The Hong Kong Polytechnic University
Trauma Exposure, Trauma
Comparative Effectiveness of SPARCS and Unified Protocol for Youth With Chronic Medical Conditions and Trauma-Related Distress
The goal of this clinical trial is to compare the effectiveness of trauma-focused therapies for improving mental health symptoms and daily functioning in youth with chronic medical conditions who have experienced psychological…
- Conditions
- Trauma Exposure, Trauma, Trauma and Stressor Related Disorder, Mental Health Functioning
- Trial name
- NCT07483333
- Testing
- Structured Psychotherapy for Adolescents Responding to Chronic Stress - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Individual
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Anthony Vesco
Malignant Pleural Effusions (Mpe), Medical Thoracoscopy
Safety and Feasibility of Medical Thoracoscopy Using Single-use Flexible Bronchoscope Versus SemiRigid Pleuroscope in Pleural Effusion
Pleural effusion is a common problem in hospital patients. It may arise from a wide range of diseases. There is a multitude of recognised causes of pleural effusion, and in addition, other pleural conditions such as pleural…
- Conditions
- Malignant Pleural Effusions (Mpe), Medical Thoracoscopy, Pleural Effusion
- Trial name
- FLEXPLEUR2 (NCT07726784)
- Testing
- Single-Use Flexible Bronchoscope, Semi-Rigid Pleuroscope
- Where
- 2 sites in Malaysia
- Volunteers
- 36 people
- Sponsor
- National University of Malaysia
Feeding Tube, Children With Medical Complexity
Let's E.A.T.! (Eating With Assistive Technology): An Intervention to Support Children With Feeding Tubes and Tracheostomies
The overall objective of this proposal is to test an interdisciplinary intervention to support the transition to oral feeding for children with feeding tubes and tracheostomies.
- Conditions
- Feeding Tube, Children With Medical Complexity, Tracheostomy, Feeding Disorder, Infancy or Early Childhood
- Trial name
- NCT06525818
- Testing
- Tube weaning therapy intervention, Feeding Group
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Chicago
Psychological Factors Affecting Other Medical Conditions, Somatic Symptom and Related Disorders
Exposure Therapy for Reactivity to Symptoms
It is unclear to what degree systematic exposure exercises contribute to the overall effects of exposure therapy (exposure and response prevention).
- Conditions
- Psychological Factors Affecting Other Medical Conditions, Somatic Symptom and Related Disorders, Bodily Distress Disorder
- Trial name
- SOMEX2 (NCT07757854)
- Testing
- Planned, systematic, exposure exercises, Response prevention
- Where
- Sweden
- Volunteers
- 360 people
- Sponsor
- Region Stockholm
Somatic Symptom and Related Disorders, Medically Unexplained Symptoms
Exposure Therapy vs. Standardized Education for Distress Related to Somatic Symptoms
The annual societal cost of medically unexplained symptoms in Sweden is approximately 40 billion SEK, i.e., similar to the annual cost of cancer.
- Conditions
- Somatic Symptom and Related Disorders, Medically Unexplained Symptoms, Psychological Factors Affecting Other Medical Conditions
- Trial name
- SOMEX1 (NCT04942028)
- Testing
- Exposure, Standardized education, Prolonged assessment
- Where
- Sweden
- Volunteers
- 161 people
- Sponsor
- Region Stockholm
State Anxiety, Psychological Stress
Can Increased Medical Competence Reduce State Anxiety in Junior Doctors in the Emergency Department?
This randomized controlled trial investigates whether an adaptive e-learning program on acute and time critical medical conditions can reduce state anxiety and improve the competence of junior doctors working in emergency…
- Conditions
- State Anxiety, Psychological Stress, Education, Medical, E-learning
- Trial name
- MINDED (NCT06842394)
- Testing
- Adaptive E-learning
- Where
- Denmark
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Internet Addiction Level, Quality of Sleep
Internet Addiction and Sleep Quality Among Medical Students
Internet addiction has become increasingly prevalent among medical students and may negatively affect sleep quality and academic performance.
- Conditions
- Internet Addiction Level, Quality of Sleep, Medical Students, Academic Performance
- Trial name
- NCT07609784
- Volunteers
- 499 people, healthy volunteers welcome
- Sponsor
- Sohag University
Insomnia, Insomnia Chronic
Cognitive Behavioral Therapy for Insomnia (CBTi) in Patients With Comorbid Somatic Disease and Insomnia
Insomnia is common with co-morbid somatic disease, e.g. rheumatic disease, cancer, heart and lung disease or gastrointestinal disorders.
- Conditions
- Insomnia, Insomnia Chronic, Sleep Initiation and Maintenance Disorders, Sleep Disorder
- Trial name
- NCT04598672
- Testing
- Cognitive behavioral therapy for insomnia (CBTi)
- Where
- Norway
- Volunteers
- 73 people
- Sponsor
- Diakonhjemmet Hospital
Obesity and Obesity-related Medical Conditions, Psychiatric Disorders
Evaluating the Effect of the STEP@STAH Semaglutide Protocol on the Physical Health Measures of Atypical Antipsychotic-Treated Patients
A significant number of patients who are prescribed anti-psychotic medication such as clozapine are considered as clinically obese (BMI >35.0).
- Trial name
- STEP@STAH (NCT06754163)
- Testing
- Semaglutide in combination with a healthy lifestyle intervention (diet and exercise)
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- St Andrew's Healthcare
Insomnia, Chronic Pain
The Young Adult Clinic (YAC) Study
The overarching aim of the Young Adult Clinic (YAC) study is to evaluate the DOZE app, a digital, transdiagnostic behavioral sleep medicine and self-management approach in young adult patients (ages 18-25) with chronic pain.
- Conditions
- Insomnia, Chronic Pain, Insomnia Due to Medical Condition
- Trial name
- YAC (NCT05147974)
- Testing
- DOZE app
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Women's College Hospital
Atrial Fibrillation (AF), Heart Failure
Somatic Health Screening for Adults in Outpatient Psychiatric Care in Denmark (SomaScreen)
People with severe mental illness have a substantially increased risk of undiagnosed and insufficiently treated somatic disease.
- Conditions
- Atrial Fibrillation (AF), Heart Failure, Asthma (Diagnosis), Chronic Obstructive Pulmonary Disease (COPD)
- Trial name
- SomaScreen (NCT07518446)
- Testing
- Somatic Health Screening for Adults in Outpatient Psychiatric Care in Denmark (SomaScreen)
- Where
- Denmark
- Volunteers
- 2,800 people
- Sponsor
- Amager Hospital
Healthy Volunteer, Mood Disorder
Mental Health Impact of COVID-19 Pandemic on NIMH Research Participants and Volunteers
Background: The COVID-19 outbreak has caused many changes to people s normal social patterns. The respiratory illness has been the major focus of public health efforts.
- Conditions
- Healthy Volunteer, Mood Disorder, Anxiety Disorder, Preexisting Medical Condition
- Trial name
- NCT04339790
- Where
- United States
- Volunteers
- 3,655 people
- Sponsor
- National Institute of Mental Health (NIMH)
Anxiety in Pregnancy, Mood Disorder Due to Specified Medical Condition
Preventing Maternal Mood, Anxiety, and Trauma Symptoms After Cesarean Delivery
Perinatal mental health disorders are the most prevalent perinatal comorbidity and are associated with the primary cause of maternal mortality in the United States (US) - suicide.
- Trial name
- NCT06949813
- Testing
- BE-OR: Brief Intervention to the Operating Room, Interaction: Facetime with Clinical Provider
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Colorado, Denver
Prisoners, Substance Use History
Calls and Coordination for Transitions of Care at Re-entry
The goal of this clinical trial is to learn if a short program for people being released from prison can help connect them to medical care.
- Conditions
- Prisoners, Substance Use History, Chronic Medical Conditions, Psychiatric Condition
- Trial name
- Call2Care (NCT06794983)
- Testing
- In-person visit with study team member, In-person visit with NCM, Phone calls and texts
- Where
- United States
- Volunteers
- 488 people
- Sponsor
- University of Wisconsin, Madison
Insomnia, Insomnia Due to Medical Condition
Sleep Treatment Education Program for Young Adult Cancer Survivors (STEP-YA)
The purpose of the study is to learn if a single online education session, with or without individualized coaching sessions, can help improve young adult cancer survivors' (YACS) sleep.
- Conditions
- Insomnia, Insomnia Due to Medical Condition, Cancer
- Trial name
- NCT05358951
- Testing
- STEP-YA with Coaching, STEP-YA without Coaching
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Dana-Farber Cancer Institute
Obsessive Compulsive Disorder, Body Dysmorphic Disorder
Outcomes of Cognitive Behavioral Therapy (CBT) Interventions Provided by Unlicensed Professionals
To examine the effectiveness and clinical care outcomes of cognitive-behavioral therapy interventions at Massachusetts General Hospital (MGH).
- Conditions
- Obsessive Compulsive Disorder, Body Dysmorphic Disorder, Tourette Syndrome, Trichotillomania
- Trial name
- NCT01075672
- Testing
- Cognitive behavioral therapy (CBT)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Massachusetts General Hospital