Clinical trials: Medication Therapy Management
Schizophrenia and Related Disorders, Drug Administration Schedule
"Extended" (Alternate Day) Antipsychotic Dosing
The study wishes to examine whether "extended" antipsychotic treatment, in this case, antipsychotic treatment every other day, is as effective as daily treatment.
- Conditions
- Schizophrenia and Related Disorders, Drug Administration Schedule, Drug Therapy, Antipsychotic Agents
- Trial name
- NCT04478838
- Testing
- Risperidone, Olanzapine, paliperidone
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Centre for Addiction and Mental Health
Medication Adherence, Self Management
Medication Adherence Enhancement in Heart Transplant Recipients
Medication-related non-adherence increases the risk of rejections and associated graft loss after solid organ transplantation. A randomized controlled intervention will use adherence enhancing strategies out of a larger sample of…
- Conditions
- Medication Adherence, Self Management, Rejection
- Trial name
- NCT00843960
- Testing
- behavioral adaptation and symptom management
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Hannover Medical School
Anaplastic Thyroid Cancer
Review of Multimodality Management of Anaplastic Thyroid Cancer
To describe the outcome of patients with anaplastic thyroid cancer treated with hyperfractionated radiotherapy and concomitant chemotherapy
- Trial name
- NCT00280852
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Alberta Health services
Hepatitis C, Chronic
A Retrospective Study of Real World Treatment Outcomes of Patients With Chronic Hepatitis C
This retrospective, observational study will assess the real world treatment out comes in the management of patients with chronic hepatitis C.
- Trial name
- NCT01705717
- Where
- Thailand
- Volunteers
- 49 people
- Sponsor
- Hoffmann-La Roche
Sickle Cell Disease
Optimizing the Management of Sickle Cell Patients on Hydroxyurea: The Value of Therapeutic Pharmacological Monitoring
Brief Summary: * A short description of the clinical study, including a brief statement of the clinical study's hypothesis, written in language intended for the lay public. Limit: 5000 characters.
- Trial name
- OPTIMDREP (NCT06464458)
- Testing
- management on hydroxyurea by therapeutic pharmacological monitoring
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Home Care, Pharmacists
Home Medication Reviews by Pharmacists in Ontario, Canada
RATIONALE: Several examples in the literature describe the types of medication management issues uncovered during the course of home-based medication reviews.
- Conditions
- Home Care, Pharmacists, Medication Therapy Management
- Trial name
- NCT02658604
- Testing
- Home medication review by a pharmacist
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Waterloo
Cervical Radiculopathy
Conservative Therapy Versus Epidural Steroids for Cervical Radiculopathy
The main objective of this study is to determine whether interventional treatment (i.e. epidural steroids), conservative therapy, or the combination, is superior for cervical radiculopathy.
- Trial name
- NCT01144923
- Testing
- Gabapentin and/or Nortriptyline, Physical therapy, Epidural Steroid Injections (ESI), Combination treatment
- Where
- 2 sites in United States
- Volunteers
- 169 people
- Sponsor
- Johns Hopkins University
Bipolar Disorder
A Safety and Efficacy Study of Ramelteon Tablets for Sublingual Administration (TAK-375SL) in the Maintenance Treatment of Bipolar 1 Disorder
To evaluate the efficacy and safety of once a day ramelteon tablets for sublingual administration (TAK-375SL) in the maintenance treatment of bipolar 1 disorder.
- Trial name
- NCT01685151
- Testing
- Ramelteon SL (Dose 1), Ramelteon SL (Dose 2)
- Sponsor
- Takeda
Major Depression
Efficacy of 18-Months of Antidepressive Medication Plus CBT or Dynamic or Supportive Psychotherapy for Recurrent Major Depression
Major Depressive Disorder affects approximately 16% of the adult population over the lifetime. Controlled studies indicate that short-term antidepressive medications or psychotherapy produce full remission in only about 46% of…
- Trial name
- NCT00220623
- Testing
- antidepressant medications, flexible drug choice, CBT, Psychodynamic or Supportive Psychotherapy
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Breast Cancer
An Innovative Smartphone Application for Adverse Event Management During Breast Cancer Adjuvant Chemotherapy
The aim of this study is to evaluate benefits of the app in breast cancer patients receiving the docetaxel, doxorubicin, and cyclophosphamide (TAC) chemotherapy.
- Trial name
- NCT05258461
- Testing
- use of a smartphone app for adverse event management, conventional adverse event management
- Volunteers
- 108 people
- Sponsor
- Peking Union Medical College Hospital
Bladder Cancer
Electromotive Mitomycin-C (EMDA-MMC) in Preventing Recurrences in High-risk Non-muscle-invasive Bladder Cancer
Disease recurrence and progression is a major issue in high risk non-muscle-invasive bladder cancer (NMIBC). The current study compares two adjuvant instillation therapies in the treatment of high risk NMIBC.
- Trial name
- FB10 (NCT03664869)
- Testing
- BCG instillation therapy, Sequential BCG and EMDA mitomycin C
- Where
- 7 sites in Finland
- Volunteers
- 300 people
- Sponsor
- Turku University Hospital
Heart Failure, Heart Failure, Systolic
Pharmacist-Assisted Titration of Rx to Implement Optimal Medical Therapy for Heart Failure
Many Veterans who are hospitalized with heart failure do not receive all the recommended heart medications at the right doses before they leave the hospital or in the weeks following discharge.
- Trial name
- PATRIOT-HF (NCT07714239)
- Testing
- Pharmacist/Cardiologist Virtual Team Digital Consultation
- Where
- United States
- Volunteers
- 585 people
- Sponsor
- VA Office of Research and Development
Candidiasis, HIV Infections
A Study to Assess the Effect of Concomitant Administration of Fluconazole on the Clinical Pharmacokinetics of Methadone
To evaluate the pharmacokinetics and safety of concomitant administration of methadone and fluconazole. Injection drug users constitute the second largest subset of the U.S.
- Trial name
- NCT00000788
- Testing
- Methadone hydrochloride, Fluconazole
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Breast Cancer, eHealth
Mitigating Toxicity by Electronic Health Portal-mediated Interactive Monitoring of Patient-reported Side Effects
Chemotherapy induces side effects varying in severity, impacting patients' quality of life and necessitating unplanned hospital care. Patient-reported outcomes (PROs) could aid in early detection and management of side effects.
- Conditions
- Breast Cancer, eHealth, Symptom Monitoring, Self Management
- Trial name
- eChemoCoach (NCT06424054)
- Testing
- eChemoCoach
- Volunteers
- 746 people
- Sponsor
- Noordwest Ziekenhuisgroep
Breast Cancer, Chemotherapy-induced Alopecia
PBMT for the Management of CIA ( HAIRLASER )
Chemotherapy (CT) remains an important treatment modality for breast cancer patients. Unfortunately, this systemic treatment comes with many quality of life impairing complications.
- Conditions
- Breast Cancer, Chemotherapy-induced Alopecia, Alopecia
- Trial name
- NCT04036994
- Testing
- Photobiomodulation therapy
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Hasselt University
Disabilities, Intellectual, Disability, Developmental
Appropriate Medication Use for Individuals With Intellectual Disabilities - A Matter of Life
The innovation idea is to develop valuable new knowledge about safe drug use in people with intellectual and/or developmental disabilities (IDDs).
- Trial name
- NCT06160102
- Testing
- Develop and implement the Framework for safe drug use in people with intellectual and/or developmental disabilities
- Where
- Norway
- Volunteers
- 110 people
- Sponsor
- Vestvagoy Municipality
Acute Depressive Episode
Efficacy and Safety of Ramelteon Sublingual in Adult Patients With Acute Depressive Episodes Associated With Bipolar I Disorder
The purpose of this study is to determine the efficacy and safety of Ramelteon, once daily (QD), sublingual (SL), in adult participants with acute depressive episodes associated with Bipolar I disorder.
- Trial name
- NCT01467700
- Testing
- Ramelteon SL
- Where
- 161 sites in United States, Argentina and 3 more
- Volunteers
- 490 people
- Sponsor
- Takeda
Bladder Neoplasm, Neoplasm Recurrence, Local
Efficacy and Safety Evaluation of EN3348 (Mycobacterial Cell Wall-DNA Complex [MCC]) as Compared With Mitomycin C in the Intravesical Treatment of Subjects With BCG Recurrent/Refractory Non-muscle Invasive Bladder Cancer
This is a phase 3 randomized, active-controlled, open-label, multicenter study that will be conducted in approximately 120 investigational sites worldwide.
- Conditions
- Bladder Neoplasm, Neoplasm Recurrence, Local, Transitional Cell, Carcinoma, Carcinoma in Situ
- Trial name
- EMBARC-RF (NCT01200992)
- Testing
- EN3348, Mitomycin C
- Where
- 72 sites in United States, Canada and 4 more
- Volunteers
- 84 people
- Sponsor
- Bioniche Life Sciences Inc.
Fibromyalgia Syndrome
Osteopathic Medicine in Fibromyalgia Syndrome
The purpose of this study is to evaluate the analgesic effects of a 6 weeks osteopathic treatment on patients with fibromyalgia.
- Trial name
- FIBROPATHIC (NCT02343237)
- Testing
- Osteopathic treatment, Factitious osteopathic treatment
- Where
- France
- Volunteers
- 101 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stress, Job, Student Burnout
Investigating the Effects of Osteopathic Manipulative Treatment on Stress Management in Medical Students
The goal of this clinical trial is to evaluate stress biomarkers, subjective stress levels, and cognitive function in medical students.
- Conditions
- Stress, Job, Student Burnout, Stress, Physiological, Stress, Psychological
- Trial name
- NCT06125574
- Testing
- Osteopathic Manipulative Medicine
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The Touro College and University System
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