Clinical trials: Medicine, Emergency
Nosocomial Infections
ED Residents MBP During CVC Placement: Sim Lab Based Training
1. Baseline performance in maximal barrier precaution technique of Emergency Medicine (EM) residents, certified in CVC placement, is poor 2.
- Trial name
- EM CVC MBP (NCT00791583)
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Migraine, Hemicrania
Home Detox in Medication Overuse Headache (MOH) During Covid-19 Emergency
Medication Overuse Headache (MOH) is a disabling condition that affects the 2% of migraine population. Medication overuse (MO) makes this condition very difficult to treat.
- Trial name
- MOHC (NCT04410536)
- Testing
- Symptomatic drugs, Bridge therapy, Mindfulness program
- Where
- Italy
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Seasonal Mood Disorder
Vitamin D Supplementation and Effects on Mood in Emergency Medicine Residents
Seasonal mood changes, and even feelings of depression, appear to have an association with decreased amounts of vitamin D in people living in geographic areas where exposure to sunlight during the winter months is relatively low.
- Trial name
- NCT03739671
- Testing
- Vitamin D, No Vitamin D
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Corewell Health South
Development, Human, Well-Being
The Impact of Professional Coaching on Early Career Academic Emergency Physicians
This research study is designed to answer the question: How does professional coaching impact early career academic emergency medicine physician goal attainment, leadership strengths, well-being, and burnout?
- Conditions
- Development, Human, Well-Being, Professional Burnout, Goals
- Trial name
- NCT03125330
- Testing
- Professional coaching
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Pediatric Emergency Medicine, Therapeutic Turnaround Time
Effectiveness of a Mobile App in Reducing Therapeutic TAT in an Emergency Department
This study is a single center, non-equivalent comparison group, pre-post study in a tertiary pediatric emergency department in Switzerland.
- Trial name
- NCT05557331
- Testing
- PIMPmyHospital (mobile app)
- Where
- 2 sites in Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Pediatric Clinical Research Platform
Healthy Volunteers
Ultrasound to View Abdominal Wall Muscle Layers
The American College of Emergency Physicians (ACEP) views ultrasound-guided nerve blocks to be a core skill for emergency medicine physicians.
- Trial name
- NCT06955013
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Corewell Health South
Polytrauma
Comparing Trauma Severity Scores Injury Severity Score "ISS", Rapid Emergency Medicine Score "REMS" and Kampala Trauma Score "KTS"
Trauma is defined as a physical injury from an external source of sudden onset and severity, which require immediate medical attention.Despite improvements in trauma systems worldwide, trauma continues to be one of the leading…
- Trial name
- NCT05544773
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Assiut University
HIV Infections
Rapid HIV Testing for Emergency Department Patients
The purpose of this study is to test data collection options in emergency departments (EDs) and to enhance ED patient awareness of the risk of HIV infection.
- Trial name
- NCT00676481
- Testing
- HIV risk education
- Where
- United States
- Volunteers
- 570 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Acute Apical Abscess
Valacyclovir Monotherapy in Pain Management of Acute Periapical Abscesses After Emergency Chamber Opening
This study is aimed to evaluate the efficacy of valacyclovir in reducing postoperative pain following emergency chamber opening for acute apical abscess .
- Trial name
- Antiviral (NCT06344195)
- Testing
- Valacyclovir 500 mg, Naproxen Sodium 550mg
- Where
- Pakistan
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Drug Overdose
Pharmacokinetics and Pharmacodynamics of a New Formulation of Nasal Naloxone for Prehospital Use
Overdose with potential deadly outcome is a serious problem among opioid abusers, not least in Norway. The annual death toll from overdose is about 250, higher than road traffic accidents.
- Trial name
- OPI-14-001 (NCT02307721)
- Testing
- Intranasal naloxone, Intramuscular naloxone, Remifentanil
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Cardiac Arrest
Effectiveness of an Interactive Cognitive Support Tablet App to Improve the Management of Pediatric Cardiac Arrest
Pediatric cardiac arrest (PCA) has a high mortality and morbidity. Its management is complex and often deviates from guideline recommendations leading to patients' worse clinical outcomes.
- Trial name
- PediAppRREST (NCT04619498)
- Testing
- PediAppRREST, AHA-PALS pocket reference card
- Where
- 4 sites in Italy
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- University of Padova
Laceration of Skin, Anxiety
IN Midazolam vs IN Dexmedetomidine vs IN Ketamine During Minimal Procedures in Pediatric ED
Pain in young children has been universally under-recognized due to their inability to describe or localize pain. Improvements in pharmacological interventions are necessary to optimize patient and family experience and allow for…
- Conditions
- Laceration of Skin, Anxiety, Discharge Time
- Trial name
- NCT05934669
- Testing
- Intranasal Midazolam, Intranasal Dexmedetomidine, Intranasal Ketamine
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Intussusception, Emergencies
Point-of-Care Ultrasonography for Intussusception
Pediatric emergency medicine (PEM) physicians are increasingly utilizing point-of-care ultrasound (POCUS). There is currently limited data regarding POCUS evaluation for intussusception in pediatric patients.
- Trial name
- NCT03360643
- Testing
- Point-of-care ultrasound prior to radiology ultrasound, Radiology-performed ultrasound
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Fatigue, Shift Work Type Circadian Rhythm Sleep Disorder
Does Fatigue Coaching Improve Functioning and Fatigue in Resident Night Shifts
Emergency Medicine (EM) requires 24/7 staff coverage resulting in healthcare workers' circadian rhythm disruptions that impair clinical and cognitive performance, physical recovery, and contribute to burnout.
- Trial name
- NCT06100809
- Testing
- Personalized coaching, Nutrition handout
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Healthy
An Open Study of the Safety and Pharmacokinetics of a Medicinal Product for Emergency Prevention of Ebola
This Phase I clinical trial was developed to study drug safety, tolerability, and pharmacokinetics of the medicine for Ebola fever emergency prevention based on monoclonal recombinant antibodies in single use in healthy…
- Trial name
- 03-AT-2017 (NCT03428347)
- Testing
- GamEMab
- Where
- Russia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation
Fracture, Bone Fracture
AI Assisted Detection of Fractures on X-Rays (FRACT-AI)
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Fracture, Bone Fracture, Dislocation, Fracture Multiple
- Trial name
- FRACT-AI (NCT06130397)
- Testing
- Cases reading, Ground truthing
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Sleep Disorder (Disorder)
The Correlation Between Sleep Quality and Sleep Aid Use and Dietary Patterns
In this study, medical staff in emergency and critical care departments were investigated. It was assumed that the use of sleep aids and dietary patterns affected their sleep quality.
- Trial name
- NCT07019948
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Wei XIA, PhD
Abdominal Pain, Flank Pain
Real Time Remote Tele-Mentored Ultrasonography in the ED
The goal of this pilot study is to evaluate the use of real time remote tele-mentored ultrasound in the emergency department at hospitals with physician shortage designation.
- Trial name
- ED RTMUS (NCT05635214)
- Testing
- real time remote tele mentored ultrasound exam
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Drug Abuse
Healthier You: Optimizing Screening, Brief Interventions, and Referral to Treatment (SBIRT) in the Emergency Department
Screening, brief interventions, and referral to treatment (SBIRT) for drug use/abuse offers opportunities for early detection, brief intervention/treatment, and substance use treatment referrals for patients in medical settings.
- Trial name
- NCT01113190
- Testing
- Computer-delivered Brief Intervention (CBI), Intervener-delivered Brief Intervention (IBI), Adapted Motivational Enhancement Therapy (AMET)
- Where
- United States
- Volunteers
- 878 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Sedation and Analgesia, Side Effect of Drug
The Effect of Ondansetron During Intramuscular Ketamine Use in Children: A Trial in Emergency Department
The purpose of this study is to evaluate the anti-emetic effect of oral ondansetron. For this evaluation, the investigators will perform a multi-center, double-blind, placebo-controled, randomized study.
- Trial name
- NCT01477242
- Testing
- Ondansetron
- Where
- South Korea
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital