Clinical trials: Medicine, Emergency
Drug Abuse
Screening, Brief Intervention, and Referral to Treatment for Drug Use
Screening, Brief Intervention, and Referral to Treatment (SBIRT) is a comprehensive, integrated public health approach to identify and deliver a spectrum of early detection and intervention services for substance use in general…
- Trial name
- SBIRT (NCT01683227)
- Testing
- Screening/motivational drug intervention
- Where
- 2 sites in United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Pain
Trial of an Oral Sucrose Solution Versus Placebo in Children 1 to 3 Months Old Needing Nasopharyngeal Aspiration
Background: Early recognition and treatment of pain among children is important for their cognitive development and their future response to pain throughout their life.
- Trial name
- NCT01544946
- Testing
- 88% sucrose po
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Drug Overdose
Pharmacokinetics and Pharmacodynamics of a New Formulation of Nasal Naloxone for Prehospital Use
Overdose with potential deadly outcome is a serious problem among opioid abusers, not least in Norway. The annual death toll from overdose is about 250, higher than road traffic accidents.
- Trial name
- OPI-14-001 (NCT02307721)
- Testing
- Intranasal naloxone, Intramuscular naloxone, Remifentanil
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Intracranial Hemorrhages, Acute Ischemic Stroke
AI Assisted Reader Evaluation in Acute Computed Tomography (CT) Head Interpretation
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Intracranial Hemorrhages, Acute Ischemic Stroke, Hydrocephalus, Cerebral Infarction
- Trial name
- AI-REACT (NCT06018545)
- Testing
- Ground truthing, Reading
- Where
- 4 sites in United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Cardiac Arrest
Tele-Support for Emergency Medical Technicians
In this manikin-based simulation study the impact of tele-support during a simulated pediatric out-of-hospital cardiac arrest scenario on emergency medical technicians' guideline adherence, on gaze behavior as well as on…
- Trial name
- POHCA (NCT06362850)
- Testing
- Tele-support
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Asthma, Pediatric ALL
Inhaled Steroids for Pediatric Asthma at Pediatric Emergency Medicine Discharge
This study evaluates the initiation of inhaled corticosteroids upon discharge from the pediatric emergency room in children under 18 presenting with asthma exacerbation.
- Trial name
- NCT03369847
- Testing
- budesonide, beclomethasone
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- New York City Health and Hospitals Corporation
Intubation, Intratracheal
Different Techniques for Emergency Cricothyroidotomy
This educational study will examine two different techniques for training emergency residents and staff on achieving a surgical airway (called a cricothyroidotomy).
- Trial name
- CRIC (NCT01107561)
- Testing
- Seldinger technique, Surgical Airway Approach
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Stress, Psychological, Emergency Medicine, Transport
Benefit of the FLYing Transport of Patients Requiring Mobile Intensive Care Unit
Patient care who requires fast and intensive care by a mobile intensive care unit in a rescue helicopter is a common practice in Auvergne since more than 3 years.
- Conditions
- Stress, Psychological, Emergency Medicine, Transport, Critical Care
- Trial name
- FLY-MICU (NCT04578054)
- Testing
- Flying transport
- Where
- France
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Acute Severe Pain
Titration of Intravenous Hydromorphone
This is an exploratory, hypothesis-generating safety and efficacy study for patients who come to the ER in acute (less than 7 days in duration) severe pain. Patients with chronic pain will not be enrolled.
- Trial name
- NCT01892709
- Testing
- Hydromorphone
- Where
- United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Abdominal Pain, Flank Pain
Real Time Remote Tele-Mentored Ultrasonography in the ED
The goal of this pilot study is to evaluate the use of real time remote tele-mentored ultrasound in the emergency department at hospitals with physician shortage designation.
- Trial name
- ED RTMUS (NCT05635214)
- Testing
- real time remote tele mentored ultrasound exam
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Anxiety, Emotional Regulation
The Impact of Therapy Dogs on Anxiety and Emotional Management in the Pediatric Emergency Department
The purpose of this study is to assess the impact of therapy dogs on children's anxiety and emotional management during a visit to the pediatric emergency department.
- Trial name
- NCT04942678
- Testing
- 10-minute visit with therapy dog and child life specialist handler
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Rhabdomyolysis, Virtual Reality
Evaluation of the Effectiveness of Using Virtual Reality Glasses in Prehospital Intervention Training for Crush Syndrome
This research is a randomized controlled study designed to develop and evaluate the effectiveness of a video-based virtual reality (VR) simulation for prehospital intervention training of crush syndrome for paramedic students.
- Conditions
- Rhabdomyolysis, Virtual Reality, Emergency Medical Services, Disaster Medicine
- Trial name
- NCT07361835
- Testing
- Virtual reality-based crush syndrome training, Traditional theoretical lecture
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Ege University
Airway Management, Endotracheal Intubation
Novel Integrated Tube-Bougie Prototype for Endotracheal Intubation in Airway Simulation
Endotracheal intubation is a critical airway management procedure that frequently requires adjunctive devices, such as stylets or elastic bougies, to facilitate successful tube placement.
- Conditions
- Airway Management, Endotracheal Intubation, Difficult Airway
- Trial name
- ITBP (NCT07747922)
- Testing
- EPATS (Integrated Tube-Bougie Prototype), Standard gum elastic bougie, Standard stylet
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Huseyin Cahit Halhalli, MD
HIV Prevention, Pre-Exposure Prophylaxis (PrEP)
Starting HIV Prevention Medicine (PrEP) During an Emergency Department Visit With a Peer Navigator
The goal of this study is to learn whether adults who visit a hospital emergency department (ED) find it acceptable to start HIV pre-exposure prophylaxis (PrEP) during that same visit, with help from a peer navigator.
- Trial name
- RAPID Response (NCT07901101)
- Testing
- RAPID Response peer navigation, Emtricitabine/tenofovir disoproxil fumarate (F/TDF)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Cardiopulmonary Arrest, Resuscitation
Reducing Prehospital Medication Errors & Time to Drug Delivery by EMS During Simulated Pediatric CPR
The study investigators will recruit paramedics in many Emergency Medical Services (EMS) in Switzerland to prepare direct intravenous (IV) emergency drugs during a standardized simulation-based pediatric out-of-hospital cardiac…
- Conditions
- Cardiopulmonary Arrest, Resuscitation, Pediatrics, Medication Errors
- Trial name
- NCT03921346
- Testing
- Mobile device app (PedAMINES™) 1st drug, Mobile device app (PedAMINES™) 2nd drug, Mobile device app (PedAMINES™) 3rd drug
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Pediatric Clinical Research Platform
Agitation
Naturalistic Adasuve Clinical Trial Study
There is limited information on the best psychoactive medication to treat agitated patients in the emergency department. The intent of this study is to fill in knowledge gaps in the current practice of treating psychiatric…
- Trial name
- NCT02877108
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mt Sinai Hospital, Chicago
HIV
Male Engagement in PMTCT Services
The study employs a quasi-experimental design in 8 public health centers in southwest Uganda offering care and treatment (C\&T) services.
- Trial name
- NCT01903889
- Testing
- clinic based intervention, clinic and community based intervention
- Where
- 7 sites in Uganda
- Volunteers
- 3,806 people, healthy volunteers welcome
- Sponsor
- FHI 360