Clinical trials: Medicine, Emergency
Acute Migraine Headache
Oral Medications for the Management of Acute Migraine Headache in the Emergency Department
The goal of this pilot randomized control trial is to assess the feasibility of our patient recruitment and data collection strategy ahead of a full scale RCT investigating the efficacy of oral v.
- Trial name
- NCT05983354
- Testing
- Oral metoclopramide and ibuprofen, Intravenous metoclopramide and ketorolac
- Sponsor
- Health Sciences North Research Institute
Emergency Department
Reorientation of Tripped Patients 4 and 5 in Emergency Department
The increase in emergency room visits is partly related to the growing increase in unscheduled care, paradoxically associated with a decrease in the outpatient supply in the city.
- Trial name
- NCT05392829
- Where
- France
- Volunteers
- 368 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Asthma Attack, Emergency Medicine
Asthma Attack in the Emergency Department : Reasons Of This Attendance
Objective: Identify modifiable factors that may affect asthma control and the use of emergency room to define customized interventions for the management of asthma prior to emergency room.
- Trial name
- AERO (NCT03099915)
- Testing
- completion of self-reported questionnaires
- Where
- 2 sites in France
- Volunteers
- 182 people
- Sponsor
- Olivier CHASSANY
Telemedicine Usage, Teleconsultation Usage
Implementation Strategy and Systemic Effects of Routine Telemedical Care in Prehospital Emergency Medicine
In two research projects a comprehensive prehospital telemedicine system was developed and general feasibility as well as impact on guideline adherence were evaluated.
- Conditions
- Telemedicine Usage, Teleconsultation Usage, Emergency Medical Service Missions
- Trial name
- NCT04127565
- Volunteers
- 51,649 people
- Sponsor
- RWTH Aachen University
Low Back Pain, Mechanical
Effectiveness of Chiropractic Application for Acute Low Back Pain
The aim of this project is to investigate the effectiveness of chiropractic application on patients who have undergone routine medication as a standard hospital treatment for mechanical low-back pain as described in the Clinical…
- Trial name
- NCT04110119
- Testing
- diclophenac sodium (75 mg, IM) and thiocolchicoside (4 mg, IM), Chiropractic Treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Medipol University
Emergency Medicine
Assessing Mixed Reality for Emergency Medical Care Delivery in a Simulated Environment
This study assessed the feasibility and effectiveness of using Mixed Reality (MR) through the use of HoloLens2TM technology to enhance emergency clinical care delivery in a simulated environment.
- Trial name
- NCT05870137
- Testing
- HoloLens2TM, Standard care
- Where
- United Kingdom
- Volunteers
- 22 people
- Sponsor
- Imperial College London
Acute Pain, Analgesics
Monitoring Side Effects Of Pain Medication Prescribing By Emergency Department In Patients Over 65
Half of the people over the age of 65 are not functioning at their optimal level because of interference from pain. > 50% of older adults had taken prescriptions of pain medication beyond a 6-month period.
- Conditions
- Acute Pain, Analgesics, Elderly
- Trial name
- MOSE65 (NCT02046681)
- Where
- 5 sites in Italy
- Volunteers
- 1,000 people
- Sponsor
- Azienda Ospedaliera S. Maria della Misericordia
Acute Hepatitis
Case Control Study of Non Viral Hepatitis Relating to Herbal Drug Use in the Emergency Department
The use of traditional Chinese herbal medicine and various forms of alternative medicine to maintain health among the Chinese ethnic group has had a long history and has been deeply rooted in the Chinese way of living for…
- Trial name
- NCT00201578
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital
Iatrogenic Disease
Incidence of Iatrogenic Diseases on Hospital's Emergency Consultations
French population grows older year after year: 24.3% people were over 60 years old in 2006 against 20.6% in 2000 and the expected number might be over 33% in 2050.
- Trial name
- EIU (NCT03960398)
- Testing
- Iatrogenic disease impact on emergency consultations
- Where
- 2 sites in France
- Volunteers
- 2,500 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Anemia
Phenotyping Acute Non-Severe Anemia in the Emergency Department
Anemia is traditionally diagnosed and managed using circulating hemoglobin concentration ([Hb]). However, [Hb] is influenced by plasma volume and may not accurately reflect the total amount of hemoglobin available for oxygen…
- Trial name
- PHENOEMEMIA (NCT07761104)
- Testing
- Total hemoglobin mass measurement, Focused transthoracic echocardiography, Near-infrared spectroscopy
- Where
- France
- Volunteers
- 59 people
- Sponsor
- Hospices Civils de Lyon
Anaphylactic Reaction, Anaphylaxis
Steroid Use in Treatment of Allergic Reactions to Food
In this study, the investigators want to find out whether a specific medication commonly used for severe allergic reactions is really necessary.
- Conditions
- Anaphylactic Reaction, Anaphylaxis, Allergy in Children, IgE Mediated Food Allergy
- Trial name
- SAFARI (NCT07341776)
- Testing
- Antihistamines, Systemic corticosteroids, Adrenaline (rescue medication)
- Where
- 2 sites in Switzerland
- Volunteers
- 160 people
- Sponsor
- Johannes Trueck
Drug Abuse
Healthier You: Optimizing Screening, Brief Interventions, and Referral to Treatment (SBIRT) in the Emergency Department
Screening, brief interventions, and referral to treatment (SBIRT) for drug use/abuse offers opportunities for early detection, brief intervention/treatment, and substance use treatment referrals for patients in medical settings.
- Trial name
- NCT01113190
- Testing
- Computer-delivered Brief Intervention (CBI), Intervener-delivered Brief Intervention (IBI), Adapted Motivational Enhancement Therapy (AMET)
- Where
- United States
- Volunteers
- 878 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Penicillin Allergy, Pediatric Emergency Medicine
Oral Challenge in the Pediatric ED
Our primary objective was to demonstrate the feasibility of utilizing a novel penicillin allergy questionnaire in the PED to identify a low-risk group of patients who will complete an oral challenge in the PED to test for an…
- Trial name
- OPEN (NCT03404804)
- Testing
- Amoxicillin
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Medical College of Wisconsin
Aging
Reducing Potentially Inappropriate Medication Prescribing for Older Patients in the ED
This research is being conducted to learn which implementation strategy of EQUIPPED is most effective to improve prescribing practices of ED providers toward older Veterans and determine the factors influencing implementation of…
- Trial name
- EQUIPPED (NCT04004936)
- Testing
- EQUIPPED with Active Feedback, EQUIPPED with Passive Feedback
- Where
- 4 sites in United States
- Volunteers
- 74 people
- Sponsor
- VA Office of Research and Development
Brain Injuries, Traumatic, Brain Injuries, Acute
Critical Hyperacute Assessment Research On Neurobiomarker Kinetics in Acute Brain Injury
Traumatic brain injury (TBI) and other conditions that reduce blood flow to the brain - such as cardiac arrest (CA) - are life-threatening medical emergencies.
- Conditions
- Brain Injuries, Traumatic, Brain Injuries, Acute, Hypoxia, Brain, Cardiac Arrest (CA)
- Trial name
- CHARON (NCT07782216)
- Where
- 4 sites in Hungary
- Volunteers
- 477 people
- Sponsor
- University of Pecs
Emergency Medicine
Development of a Multipurpose Dashboard to Monitor the Situation of Emergency Departments
An emergency department (ED) is a healthcare service that provides the first clinical assessment and treatment to patients with various acute conditions.
- Trial name
- eCREAM-UC2 (NCT06372379)
- Testing
- no intervention
- Where
- 2 sites in Italy
- Volunteers
- 162,000 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Suicide, Drug Poisoning
Voluntary Drug Poisoning by Psychoactive Molecules: Identify Cognitive Markers
To identify in patients admitted for Voluntary drug poisoning (IMV) by psychoactive substances, T1 predictors of T2 recall of psychiatric interview and care project.
- Trial name
- IMG-COG (NCT03481192)
- Testing
- Two visits for evaluation
- Where
- France
- Volunteers
- 103 people
- Sponsor
- University Hospital, Toulouse
Cerebrovascular Accident (CVA)
Strokecopilot: A Precision Medicine Tool in the Stroke Emergency
Ischemic stroke or cerebral infarction (CI) is an immediate emergency affecting approximately 100,000 - 150,000 patients each year in France and is managed in the neurovascular intensive care unit (NICU).
- Trial name
- Strokecopilot (NCT05534295)
- Where
- France
- Volunteers
- 10,000 people
- Sponsor
- University Hospital, Strasbourg, France
Telemedicine, Disaster Medicine
Feasibility of Telemedicine Under Ambulance Station Conditions
Our aim is to evaluate the feasibility of telemedicine in context of medical service in an ambulance station and in a further step in context of civil defense situations.
- Conditions
- Telemedicine, Disaster Medicine, Emergency Medicine
- Trial name
- NCT05388071
- Testing
- Usage of telemedicine and tele-consultation for treatment
- Where
- Germany
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Febrile Neutropenia, Drug-Induced
Predictive Value of ProCalcitonin for the Detection of Bacteraemia in Patients Presenting to the Emergency Department for Low Risk Chemo-induced Febrile Neutropenia
CALIF study is a monocentric observational study which aim is to analyse the value of adding procalcitonin (PCT, a pre-hormon increased in bacterial infection and septicaemia) in the management of chemo-induced febrile…
- Trial name
- CALIF (NCT03182465)
- Testing
- Value of ProCalcitonin
- Where
- Belgium
- Volunteers
- 54 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain