Clinical trials: Medicine, Emergency
HIV
Male Engagement in PMTCT Services
The study employs a quasi-experimental design in 8 public health centers in southwest Uganda offering care and treatment (C\&T) services.
- Trial name
- NCT01903889
- Testing
- clinic based intervention, clinic and community based intervention
- Where
- 7 sites in Uganda
- Volunteers
- 3,806 people, healthy volunteers welcome
- Sponsor
- FHI 360
Pain
An Efficacy and Safety of Proprietary Formulations of Oral Ketamine + Aspirin in Treatment of Acute Headache
Headaches affect over 50% of patients annually, with close to 4% of ED visits for headache. Most headaches managed in the ED are benign, with 90% of these headaches classified as tension, migraine, or cluster.
- Trial name
- NCT04860713
- Testing
- aspirin and ketamine, Nurtec (Rimegepant)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Antonios Likourezos
Emergency Service, Hospital, Medication Reconciliation
Medication Reconciliation in an Emergency Department: How to Prioritize Patients ?
Medication reconciliation has proven its efficiency in improving patients' care, especially for emergency patients. This study aimed to identify risk factors of unintended medication discrepancies (UMD) in an emergency…
- Trial name
- NCT03955965
- Testing
- Medication reconciliation
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Fondation Hôpital Saint-Joseph
Asthma Attack, Asthma Control
Boosting Referrals to Asthma Specialists for Patients Seen at the Emergency Room for an Asthma Exacerbation
This study is testing a new way to help adults with asthma get follow up care after an emergency room (ER) visit for an asthma attack.
- Conditions
- Asthma Attack, Asthma Control, Asthma Exacerbations, Asthma
- Trial name
- NCT07396987
- Testing
- ER-Initiated Telehealth Referral
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Juan Carlos Cardet
Abdominal Pain, Isolated Extremity Fracture
Morphine or Ketamine for Analgesia
Pain is common in children presenting to the emergency department but is frequently undertreated, leading to both short- and long-term consequences.
- Conditions
- Abdominal Pain, Isolated Extremity Fracture, Pain, Pediatrics
- Trial name
- MoKA (NCT06835504)
- Testing
- Ketamine hydrochloride, Morphine sulphate
- Where
- 8 sites in United States
- Volunteers
- 1,010 people
- Sponsor
- Columbia University
Emergence Delirium, Anesthesia
Effect of Different Drugs on Emergency Delirium in Preschool Age Patient
Emergence delirium (ED) was first described by Eckenhoff and colleagues in the 1960s and is defined in pediatric anesthesia as 'dissociated state of consciousness in which child is irritable, uncompromising, uncooperative…
- Trial name
- NCT07057193
- Testing
- Dexmedetomidine group (D group), Ketamine group (K group), Midazolam group (M group)
- Where
- Egypt
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Acute Non-specific Low Back Pain
Adjunctive Wet Cupping for Acute Non-Specific Low Back Pain
This prospective randomized controlled trial evaluated the effectiveness and safety of adjunctive wet cupping therapy combined with standard pharmacological treatment in adults presenting to the emergency department with acute…
- Trial name
- NCT07837596
- Testing
- Wet Cupping Therapy, Dexketoprofen
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ataturk University
Cardiopulmonary Arrest, Resuscitation
Reducing Prehospital Medication Errors & Time to Drug Delivery by EMS During Simulated Pediatric CPR
The study investigators will recruit paramedics in many Emergency Medical Services (EMS) in Switzerland to prepare direct intravenous (IV) emergency drugs during a standardized simulation-based pediatric out-of-hospital cardiac…
- Conditions
- Cardiopulmonary Arrest, Resuscitation, Pediatrics, Medication Errors
- Trial name
- NCT03921346
- Testing
- Mobile device app (PedAMINES™) 1st drug, Mobile device app (PedAMINES™) 2nd drug, Mobile device app (PedAMINES™) 3rd drug
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Pediatric Clinical Research Platform
Educational Problems, Orthopedic Disorder
Assessment of an Orthopedic Surgery Rotation on Musculoskeletal Competency in Emergency Medicine Residency Training
Patient commonly present with orthopedic injuries in the emergency department. Musculoskeletal education has not historically been emphasized in American medical schools, and the effectiveness of an orthopedic surgery rotation…
- Conditions
- Educational Problems, Orthopedic Disorder, Emergencies
- Trial name
- NCT03944746
- Testing
- Education Curriculum
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Jared L. Cohen
Violence, Violence, Non-accidental
Optimization Study of the Wraparound Care for Youth Injured by Violence Program
This study is an optimization study to evaluate how a wraparound program for youth who have been injured by violence helps to change violence related attitudes and beliefs, change individual risk factors for violence and reduce…
- Conditions
- Violence, Violence, Non-accidental, Physical Violence
- Trial name
- NCT02573480
- Testing
- Wraparound care
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University of Manitoba
Tracheal Intubation Morbidity
Comparison of Intubation Duration Between Rapid Sequence Intubation (RSI) Technique and Non-RSI Technique
The purpose of this study is to evaluate intubation duration between rapid sequence intubation technique (RSI) and non-rapid sequence intubation technique (non-RSI) performed by emergency medicine residents in Siriraj hospital.
- Trial name
- NCT01474252
- Testing
- RSI
- Where
- Thailand
- Volunteers
- 224 people
- Sponsor
- Siriraj Hospital
Asthmatic Patients, MDI
Assessment of Emergency Spacers Versus Traditional Spacers for Delivery of Aerosolized Drugs
The goal of this clinical trial is to evaluate the performance, feasibility, and safety of emergency spacers compared to traditional spacers for the delivery of aerosolized drugs using pMDI.
- Conditions
- Asthmatic Patients, MDI, Aerosol Generating Procedure
- Trial name
- NCT06816342
- Testing
- Ventoline® Evohaler® 100 µg/inhalation pMDI alone, Ventoline® Evohaler® 100 µg/inhalation pMDI connected to Able spacer, Ventoline® Evohaler® 100 µg/inhalation pMDI connectec to Tips-Haler spacer
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Beni-Suef University
Migraine Headache
Effectiveness and Acceptability of MINDFULNESS by Smartphone, for Patients with Chronic Migraine and Medication Overuse
Chronic Migraine is a disabling condition that affects the 2% of migraine population. It is often associated with medication overuse that makes this condition very difficult to treat.
- Trial name
- ChroMig-Smart (NCT04389372)
- Testing
- Mindfulness
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Medication Reconciliation, Emergency Department
Medication Histories Conducted by Nurses (RNs), Pharmacy Techs (CPhTs) & Pharmacists (RPhs)
Up to 50% of medication errors and 20% of adverse drug reactions (ADRs) in the hospital setting are estimated to be related to communication issues regarding patient medications at various transition points of care from admission…
- Trial name
- NCT01065675
- Testing
- Medication reconciliation completed by a RN, CPhT, or RPh
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Wesley Medical Center
Emergency Department, Clinical Pharmacist
Integrating the Clinical Pharmacists Into Emergency Department Teams
The "Emergency Department (ED) Pharmacist" is an integrated part of the ED interdisciplinary team in many countries, which have shown to improve medication safety and reduce costs related to hospitalisations.
- Trial name
- ED-PHARM (NCT04722588)
- Testing
- Introducing clinical pharmacists to the interdisciplinary ED team.
- Where
- 3 sites in Norway
- Volunteers
- 30,888 people
- Sponsor
- Hospital Pharmacy of North Norway Trust
HIV Counseling and Testing, HIV Infections
An Effective Alternative to the Standard Referral System for HIV Testing in the Emergency Department During Off Hour Tours: A Randomized Trial
To compare HIV testing rates in ED patients offered video-assisted informed consent off-hours versus those referred to an HIV counselor the next business day.
- Trial name
- NCT00218881
- Testing
- HIV educational video
- Where
- United States
- Volunteers
- 408 people
- Sponsor
- North Bronx Healthcare Network
Cerebrovascular Accident (CVA)
Strokecopilot: A Precision Medicine Tool in the Stroke Emergency
Ischemic stroke or cerebral infarction (CI) is an immediate emergency affecting approximately 100,000 - 150,000 patients each year in France and is managed in the neurovascular intensive care unit (NICU).
- Trial name
- Strokecopilot (NCT05534295)
- Where
- France
- Volunteers
- 10,000 people
- Sponsor
- University Hospital, Strasbourg, France
Critical Care Medicine, Emergency Medical Services
The TTM and ASM Trial
Sudden cardiac arrest (SCA) remains one of the major challenges in clinical care. Although improvements in resuscitation quality have increased the likelihood of return of spontaneous circulation (ROSC), most patients still fail…
- Conditions
- Critical Care Medicine, Emergency Medical Services, Cardiac Arrest (CA), Seizure
- Trial name
- NCT07835802
- Testing
- Prophylactic ASM, Hypothermic, Normothermic
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Emergency Department
Reorientation of Tripped Patients 4 and 5 in Emergency Department
The increase in emergency room visits is partly related to the growing increase in unscheduled care, paradoxically associated with a decrease in the outpatient supply in the city.
- Trial name
- NCT05392829
- Where
- France
- Volunteers
- 368 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Acute Myocardial Infarction
Effect of the Biomarker Copeptin in Managing Patients With Suspected Acute Coronary Syndrome (ACS)
Acute chest pain is commonly known to be the classic symptom of acute myocardial infarction. Of the many patients which visit the Emergency Department because of chest pain, less than half do actually suffer from an acute…
- Trial name
- BiC-8 (NCT01498731)
- Testing
- Discharge home
- Where
- 6 sites in Austria, Germany and 1 more
- Volunteers
- 902 people
- Sponsor
- Charite University, Berlin, Germany