Clinical trials: Meibomian Gland Dysfunction, active
GVHD, Meibomian Gland Dysfunction (Disorder)
Autologous Serum Obtained by a Closed-Circuit Collection Device
Autologous serum eye drops (ASED) are an established therapy for ocular surface diseases; however, their preparation can be costly and may not be available due to the need for germ-free conditions.
- Conditions
- GVHD, Meibomian Gland Dysfunction (Disorder), Stevens-Johnson Syndrome, Limbal Keratoconjunctivitis
- Trial name
- NCT07014059
- Testing
- Autologous Serum 20%
- Where
- Brazil
- Volunteers
- 16 people
- Sponsor
- GIANCARLO FATOBENE
Meibomian Gland Dysfunction, Dry Eye Syndromes
Ocular Surface Changes and Meibomian Gland Dysfunction in Rheumatologic Patients
This observational study aims to assess the frequency and severity of Meibomian Gland Dysfunction (MGD) and associated ocular surface changes in patients with systemic autoimmune rheumatic diseases compared with healthy…
- Conditions
- Meibomian Gland Dysfunction, Dry Eye Syndromes, Rheumatoid Arthritis, Systemic Lupus Erythematosus
- Trial name
- NCT07810569
- Volunteers
- 150 people
- Sponsor
- Assiut University
Dry Eye, Evaporative Dry Eye Disease
Microbiome-Focused Food Supplement for Evaporative Dry Eye Due to Meibomian Gland Dysfunction
Dry eye disease (DED) is a common chronic condition characterized by ocular surface discomfort and tear film instability. Evaporative DED associated with meibomian gland dysfunction (MGD) is a frequent phenotype and is often…
- Conditions
- Dry Eye, Evaporative Dry Eye Disease, Meibomian Gland Dysfunction (Disorder)
- Trial name
- NCT07453212
- Testing
- Dietary Supplement: Microbiome-targeted oral supplement
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Varol TUNALI
Dry Eye Disease (DED), MGD-Meibomian Gland Dysfunction
The Effect of Eyelid Support Plate Assisted Eyelid Massage on Meibomian Gland Dysfunction: a Randomized Controlled Trial
This study aims to conduct a randomized controlled clinical trial to compare the efficacy of a new type of massage device - eyelid support plate and glass rod assisted eyelid massage in improving MGD related dry eye symptoms, and…
- Trial name
- NCT07633938
- Testing
- eyelid support plate assisted eyelid massage, glass rod assisted eyelid massage
- Where
- China
- Volunteers
- 142 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Meibomian Gland Dysfunction (MGD)
Efficacy of Vevye Ophthalmic Solution for the Treatment of Meibomian Gland Dysfunction
This research study evaluates a prescription eye drop called Vevye® (cyclosporine 0.1%) for adults who have meibomian gland dysfunction (MGD), a common eye condition that can cause dry, irritated, or burning eyes.
- Trial name
- NCT07224529
- Testing
- Vevye(Cyclosporine 0.1% Ophthalmic Solution)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Alabama at Birmingham
Dry Eye, Meibomian Gland Dysfunction
Ocular Surface Health and Tear Film Stability With a Nasal Spray Dry Eye Treatment
The purpose of this study is to examine the impact of nasal spray treatment on Meibomian gland function and ocular surface health in symptomatic dry eye patients with mild to moderate Meibomian gland dysfunction (MGD).
- Trial name
- NCT07606625
- Testing
- Varenicline 0.03Mg/Spray Nasal Soln
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of California, Berkeley
Meibomian Gland Dysfunction (Disorder)
TearCare in Young Adults
This study is a non-randomized, open-label, interventional trial of TearCare® eyelid warming and manual meibomian gland expression in young adults with clinically significant meibomian gland dysfunction (MGD).
- Trial name
- NCT07579156
- Testing
- TearCare®
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Alabama at Birmingham
Dry Eye Syndromes, Meibomian Gland Dysfunction
Therapeutic Efficacy and Safety of Non-Invasive RF Treatment in Refractory MGD
The goal of this prospective, 24-week, double-masked, randomized, sham-controlled clinical trials to compare clinical efficacy and safety of RF and MGX with MGX alone in patients with meibomian gland dysfunction-related dry eye…
- Trial name
- NCT06220474
- Testing
- The Thermage FLX System
- Where
- 2 sites in Hong Kong
- Volunteers
- 112 people
- Sponsor
- The University of Hong Kong
Dry Eye Syndromes, Meibomian Gland Dysfunction (Disorder)
Blink Reminders and Meibomian Gland Loss in Digital Screen Users
This randomized clinical trial aims to evaluate if a blink reminder program ('BlinkEasy') reduces the progression of Meibomian gland loss in intensive digital screen users over three months , using infrared meibography as the…
- Trial name
- NCT07430137
- Testing
- Digital Blink Reminder Software (BlinkEasy), Visual Hygiene Education (20-20-20 Rule).
- Volunteers
- 28 people
- Sponsor
- Asociación para Evitar la Ceguera en México
Dry Eye Syndromes, Meibomian Gland Dysfunction
Photobiomodulation With REd vs BluE Light (REBEL)
The use of photobiomodulation or low-level light therapy (LLLT) in the ophthalmic field stemmed from dermatology which has shown impact on skin blood flow and regeneration.
- Conditions
- Dry Eye Syndromes, Meibomian Gland Dysfunction, Blepharitis
- Trial name
- NCT06371300
- Testing
- Red LLLT, Blue LLLT
- Where
- 2 sites in New Zealand, United Kingdom
- Volunteers
- 36 people
- Sponsor
- Aston University
Dry Eye, Meibomian Gland Dysfunction (Disorder)
Comparing Tear Proteomics Profile in Dry Eye Disease pre-and Post-treatment With Low Level Light Therapy
The purpose of this research study is to understand the mechanism of action of low level light therapy and also potentially yield markers associated with good treatment response.
- Trial name
- NCT07329712
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Singapore National Eye Centre
Dry Eye Disease, Meibomian Gland Disease
Treating Meibomian Gland Disease in a Pediatric Population
Dry Eye Disease (DED) is commonly encountered among eye care professionals. DED is a disease of the tears and ocular surface that is multi-factorial resulting in a wide range of symptoms and signs with potentially damaging…
- Trial name
- LLLT in Peds (NCT07229001)
- Testing
- Low level light treatment, warm compress and artificial tear
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Illinois College of Optometry
Dry Eye, Meibomian Gland Dysfunction (Disorder)
Low Level Light Therapy & Skin Pigmentation
The goal of this clinical trial is to determine if there is a difference in eyelid temperature after low-level light therapy (LLLT) in individuals with different amounts of skin pigmentation and dry eye/meibomian gland disease.
- Trial name
- NCT07173530
- Testing
- Three 15-minute low-level light therapy sessions using Light Emitting Diodes of wavelength 633nm (Essilor epi-c plus).
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Houston
Meibomian Gland Dysfunction, Dry Eye Disease
Clinical Study Evaluating Nordlys™ SWT IPL for Dry Eye Disease (DED) Due to MGD
Clinical Study Evaluating Nordlys™ System with Selective Waveband Technology (SWT)® Intense Pulsed Light (IPL) Applicators for Dry Eye Disease (DED) due to Meibomian Gland Dysfunction (MGD).
- Trial name
- NCT06064071
- Testing
- Nordlys SWT IPL, Meibomian Gland Expression (MGX)
- Where
- 3 sites in United States, Argentina
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Candela Corporation
Excess Skin of Both Eyelids, Contrast Sensitivity
The Effect of Upper Blepharoplasty on Vision Quality in the Early Postoperative Period
Contrast sensitivity (CS) and tear film (TF) changes are noted in late postoperative period after upper blepharoplasty (UB), while the same was rarely investigated in the early postoperative period.
- Conditions
- Excess Skin of Both Eyelids, Contrast Sensitivity, Tear Film Insufficiency of Both Eyes, Corneal Topography
- Trial name
- NCT05549713
- Testing
- Upper blepharoplasty
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- Osijek University Hospital
Evaporative Dry Eye Disease
Comparative Efficacy Study to Demonstrate the Non-inferiority of I-DROP® MGD Versus 2 Competitor Eye Drops in Managing Evaporative Dry Eye
A Pilot Comparative study between I-DROP MGD vs two commercially available lubricant eye drops for the management of evaporative dry eye
- Trial name
- NCT06686368
- Testing
- I-DROP MGD, Theloze Duo, Systane Complete PF
- Volunteers
- 60 people
- Sponsor
- I-MED Pharma
Contact Lens Discomfort, Meibomian Gland Dysfunction
Meibomian Gland Dysfunction Management
The purpose of this study is to compare electronic debridement of the eyelid margin (BlephEx) to manual debridement of the eyelid margin as treatment options for patients intolerant to contact lens wear consequent to Meibomian…
- Trial name
- NCT03652337
- Testing
- BlephEx, Manual debridement
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of the Incarnate Word