Clinical trials: Meibomian Gland Dysfunction (Disorder)
Dry Eye
Comparing Efficacy of Tea Tree Oil Versus Topical Azithromycin in Treating Dry Eye
This study aims to compare the effects of azithromycin and tea tree oil on the clinical outcomes and inflammatory profile of patients with MGD-associated DED.
- Trial name
- NCT06921525
- Testing
- Tea Tree Oil Topical Application Oil, Azithromycin Ophthalmic Solution
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ehab Mohamed Elsayed Mohamed Saad
Dry Eye Disease, Meibomian Gland Dysfunction
Effect of Sunflower Lecithin Supplementation on Meibomian Gland Function in Adults With Dry Eye Disease
This prospective study will evaluate the effect of oral sunflower lecithin dietary supplementation on meibomian gland function in adults with dry eye disease.
- Trial name
- NCT06058559
- Testing
- Sunflower lecithin, Olive oil
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- George Washington University
Meibomian Gland Dysfunction
Efficacy of 0.05 % Cyclosporine Ophthalmic Emulsion Compare With Tear in Meibomian Gland Dysfunction
To evaluate the efficacy of 0.05% cyclosporine ophthalmic emulsion (Restasis® , Allergan) versus an artificial tears alone in patients with meibomian gland dysfunction that have abnormal tear quality and quantity by subjective…
- Trial name
- NCT00705510
- Testing
- 0.05% cyclosporin eye drop
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Mahidol University
Excess Skin of Both Eyelids, Contrast Sensitivity
The Effect of Upper Blepharoplasty on Vision Quality in the Early Postoperative Period
Contrast sensitivity (CS) and tear film (TF) changes are noted in late postoperative period after upper blepharoplasty (UB), while the same was rarely investigated in the early postoperative period.
- Conditions
- Excess Skin of Both Eyelids, Contrast Sensitivity, Tear Film Insufficiency of Both Eyes, Corneal Topography
- Trial name
- NCT05549713
- Testing
- Upper blepharoplasty
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- Osijek University Hospital
Chalazion, Dry Eye Syndromes
Treatment of Meibomian Gland Dysfunction and Evaporative Dry Eye
The objective of this study is to evaluate the clinical utility, safety and effectiveness of the Manual Mini System compared to standardized warm compress therapy for application of controlled, localized heat therapy in adult…
- Trial name
- NCT00832130
- Testing
- Manual Mini System, iHeat Portable Warm Compress Therapy
- Where
- 11 sites in United States
- Volunteers
- 139 people
- Sponsor
- TearScience, Inc.
Meibomian Gland Dysfunction, Cataract
Efficacy of LipiFlow in Patients Affected by Meibomian Gland Dysfunction in Reducing Post-cataract Surgery Dry Eye
Dry Eye Disease (DED) is a disease of the ocular surface which may be secondary to a variety of causes, including cataract surgery.
- Conditions
- Meibomian Gland Dysfunction, Cataract, Surgery--Complications, Dry Eye
- Trial name
- LIPICAT (NCT05062564)
- Testing
- LipiFlow Thermal pulsation system, Eyelid warm compresses plus massages
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Dry Eye, Neuropathic Eye Pain
Azithromycin for Meibomian Gland Disease
This study aims to elucidate the effectiveness of oral azithromycin in treating symptomatic dry eye syndrome secondary to Meibomian gland dysfunction.
- Conditions
- Dry Eye, Neuropathic Eye Pain, Ocular Microbiome, Depression, Anxiety
- Trial name
- NCT03953118
- Testing
- Azithromycin Oral Product
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of California, San Francisco
Meibomian Gland Dysfunction of Unspecified Eye, Unspecified Eyelid
Analysis of Postoperative Ocular Surface Changes and Intervention Effect After PPV in MGD Dry Eye Patients
AIM: To observe ocular surface changes after phacovitrectomy in patients with mild to moderate meibomian gland dysfunction (MGD)-type dry eye and track clinical treatment response using a Keratograph 5M and a LipiView…
- Trial name
- NCT05771194
- Testing
- Routine preoperative and postoperative anti-infection therapy, artificial tear therapy, Cleaning, hot compresses and massage of the meibomian gland
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Eye Hospital
Evaporative Dry Eye Disease
Effect of Thermal Pulsation System (Lipiflow) Treatment for Ocular Surface Disease Due to Meibomian Gland Dysfunction
Meibomian glands are a kind of sebaceous gland located in the tarsus of lower and upper lids and their function is to express lipids to the tear film.
- Trial name
- NCT03843983
- Testing
- Lipiflow® application
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA
Dry Eye, Evaporative Dry Eye Disease
Microbiome-Focused Food Supplement for Evaporative Dry Eye Due to Meibomian Gland Dysfunction
Dry eye disease (DED) is a common chronic condition characterized by ocular surface discomfort and tear film instability. Evaporative DED associated with meibomian gland dysfunction (MGD) is a frequent phenotype and is often…
- Conditions
- Dry Eye, Evaporative Dry Eye Disease, Meibomian Gland Dysfunction (Disorder)
- Trial name
- NCT07453212
- Testing
- Dietary Supplement: Microbiome-targeted oral supplement
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Varol TUNALI
Meibomian Gland Dysfunction
Study to Determine the Effect of Azasite on Corneal Surface Irregularity
The purpose of this study is to evaluate the effect of Azasite on patients with corneal surface irregularity (meibomian gland dysfunction).
- Trial name
- NCT01797107
- Testing
- Azasite
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Philadelphia Eye Associates
Palpebral Pathologies, Ocular Surface Disease
Management of Eyelid Disorders by Ophthalmologists in Usual Medical Practice
The purpose of this study is to determine the incidence and characteristics of eyelid inflammatory disorders during general ophthalmological consultations and to demonstrate association between palpebral pathologies and ocular…
- Conditions
- Palpebral Pathologies, Ocular Surface Disease, Meibomian Gland Dysfunction
- Trial name
- MEIBUM (NCT01552174)
- Where
- 2 sites in Germany, Spain
- Volunteers
- 185 people
- Sponsor
- Laboratoires Thea
Dry Eye Syndromes
Estrogen and the Outer Eye in Women During Fertility Treatment
The purpose of this study is to determine the relation between estrogen and progesterone levels, and between dryness of the eyes, in women during their fertile years.
- Trial name
- NCT02072122
- Volunteers
- 30 people
- Sponsor
- Meir Medical Center
Meibomian Gland Dysfunction
Intraductal Meibomian Gland Probing Trial
In this research study, the investigators are looking at the effects of Meibomian Gland Probing (MGP) versus a sham (fake) procedure in patients with refractory MGD who have already tried traditional management with no success in…
- Trial name
- MGP (NCT02256969)
- Testing
- Blephamide, GenTeal PM Night-Time, Meibomian Gland Probing
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Joseph B. Ciolino, MD
Dryness, Dry Eye Syndromes
Prevalence of Different Etiologies of Ocular Dryness in Patients Previously Diagnosed With Dry Eye Disease in A Sample of Egyptian Patients
Proposed Study Title: Prevalence of Different Etiologies of Ocular Dryness in Patients Previously Diagnosed with Dry Eye
- Conditions
- Dryness, Dry Eye Syndromes, Meibomian Gland Dysfunction
- Trial name
- NCT05598437
- Testing
- Dry eye device
- Where
- 2 sites in Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Roweis adel youssef
Meibomian Gland Dysfunction, Demodex Infestation of Eyelid
Effect of an Exploratory Vehicle on Meibomian Gland Dysfunction in Patients With Demodex
The purpose of this study is to evaluate and compare the effect of two dosing regimens, BID versus TID dosing, of an Exploratory Vehicle (EV) on meibomian gland dysfunction (MGD) in patients with Demodex lid infestation.
- Conditions
- Meibomian Gland Dysfunction, Demodex Infestation of Eyelid, Blepharitis, Demodectic Blepharitis
- Trial name
- Rhea (NCT06054217)
- Testing
- Vehicle of TP-03
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Tarsus Pharmaceuticals, Inc.
Dry Eye Disease
Topical Statin Eye Drop in the Management of the Dry Eye
In the first stage, to evaluate the safety of the topical medication produced by Sina Pharmaceuticals, this medication is experimentally tested on 10 volunteer patients.
- Trial name
- NCT06208384
- Testing
- Statin eye drop
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Meibomian Gland Dysfunction, Dry Eye
Randomized Controlled Trial of Long-term Treatment Effectiveness for Meibomian Gland Dysfunction (MGD) and Dry Eye
The study objective is to evaluate the long-term treatment effectiveness for adult patients with meibomian gland dysfunction (MGD) and evaporative dry eye by: 1) comparing the LipiFlow® System to a standardized daily warm…
- Trial name
- NCT01521507
- Testing
- LipiFlow System, Warm Compress Therapy + Lid Scrub
- Where
- 9 sites in United States
- Volunteers
- 200 people
- Sponsor
- TearScience, Inc.
Meibomian Gland Dysfunction
Stability of Biometry in Meibomian Gland Dysfunction
Accurate biometry is an essential and indispensable tool in preoperative cataract surgery setting to yield optimal postoperative refractive outcome.
- Trial name
- NCT04322656
- Testing
- Lipiflow treatment
- Where
- Austria
- Volunteers
- 31 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Dry Eye, Meibomian Gland Dysfunction (Disorder)
Low Level Light Therapy & Skin Pigmentation
The goal of this clinical trial is to determine if there is a difference in eyelid temperature after low-level light therapy (LLLT) in individuals with different amounts of skin pigmentation and dry eye/meibomian gland disease.
- Trial name
- NCT07173530
- Testing
- Three 15-minute low-level light therapy sessions using Light Emitting Diodes of wavelength 633nm (Essilor epi-c plus).
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Houston