Clinical trials: Memory, Episodic
Epilepsy
Evaluation of Memory and Forgetting in Patients With Epilepsy
Drug-resistant focal epilepsy (DRFE) is frequently associated with complications of varying severity that impair patient's quality of life.
- Trial name
- EPIMNESIE (NCT04924933)
- Testing
- Computerised associative memory task using abstract words and landscape photographs
- Where
- France
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Neuropsychological Tests, Memory
Adaptation and Normalization of a Verbal Episodic Memory Test in French Sign Language
To date, neuropsychological assessment of deaf signing persons is complicated by a lack of resources, especially the absence of tools available in French Sign Language (LSF).
- Conditions
- Neuropsychological Tests, Memory, Alzheimer Disease, Deafness
- Trial name
- RL-RI-LSF (NCT06902753)
- Testing
- Questionnaire and Physical Exam
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Episodic Memory
The Influence of Collective Schemas on Individual Memory (MULTIBRAIN_1)
Schemas describe mental structures storing recurrent and organized pattern of information. Schemas may have a strong influence on the process of storing and retrieving new information into memory.
- Trial name
- MULTIBRAIN_1 (NCT02172677)
- Testing
- Episodic memory task, fMRI
- Where
- France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Infant Nutrition Disorders, Health Behavior
Sharing Histories: Test of a Teaching Method for Community Health Workers
The purpose of this study is to determine the effectiveness of an innovative methodology for training Community Health Workers that will improve their effectiveness in educating mothers to adopt best practice health behaviors in…
- Trial name
- NCT02903602
- Testing
- Sharing Histories training method for CHW, Standard training method for CHW
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Future Generations Graduate School
Childhood Absence Epilepsy [Pyknolepsy]
Functional Magnetic Resonance Imaging (fMRI) Study of Memory in Children
Memory is a cognitive function whose development is still poorly documented in children, but which is often disturbed in temporal epilepsy. There are no studies about the disorders of episodic memory.
- Trial name
- NCT00242905
- Testing
- Study of memory using MRI
- Where
- 2 sites in France
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cognitive Impairment, Autoimmune Encephalitis
To Explore Cognitive Neural Mechanism of Autoimmune Encephalitis by Using Neuropsychological Tests and Multi-modal MRI
Most of patients with autoimmune encephalitis are left with permanent cognitive deficits of varying severity. The patients' life and career would be affected definitely by cognitive deficits.
- Trial name
- NCT03530462
- Testing
- rituximab, cyclophosphamide, Steroids
- Where
- China
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Healthy Volunteers
Effects of THC and CBD on Human Episodic Memory Function
THC and CBD have distinct symptomatic and behavioral effects. In healthy individuals, THC can induce psychotic symptoms and anxiety, and can impair memory.
- Trial name
- NCT02291562
- Testing
- Tetrahydrocannabinol, Cannabidiol
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Mild Cognitive Impairment, Alzheimer Disease
Understanding Brain Mechanisms Involved in Autobiographical Memory
The overall objective of this project is to characterize the spatiotemporal dynamics of brain oscillations underpinning autobiographical memory (ABM) and the modulation of the memory network using non-invasive brain stimulation.
- Conditions
- Mild Cognitive Impairment, Alzheimer Disease, Memory Loss
- Trial name
- NCT05710549
- Testing
- high-density electroencephalography (hdEEG), Transcranial alternating current stimulation (tACS)
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Lucie Bréchet
Alzheimer Disease, Memory Loss
Home-based Brain Stimulation for Memory
The proposed project aims to systematically examine the feasibility of remote, caregiver-led tACS for older adults who are vulnerable to memory decline.
- Trial name
- MemStim-home (NCT04783350)
- Testing
- Transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Healthy Older Adults
Transcranial Alternating Current Stimulation for the Improvement of Episodic Memory in Healthy Older Adults
Memory complaints are a common symptom among Subjective Cognitive Decline, Mild Cognitive Impairment and Alzheimer disease. Indeed, episodic memory and Alzheimer disease are highly sensitive to aging.
- Trial name
- NCT06284720
- Testing
- Gamma tACS (40 Hz) over the precuneus
- Where
- Portugal
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Universidade Católica Portuguesa
Test Anxiety
Influence of Chocolate With Plant Additives on Episodic Memory in Healthy Subjects Experiencing Test Anxiety
Randomized, blind parallel group design. Single intake of 55 g high Epicatechin /Melissa dark chocolate containing 160 mg Epicatechin per 55 g serving or single intake of 55 g low Epicatechin/ oat bran white chocolate containing…
- Trial name
- MaRS-Basel (NCT03382067)
- Testing
- High Epicatechin/ Melissa, Low Epicatechin/ Oat bran
- Where
- Switzerland
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Episodic Memory
The Dynamics of Representational Change Underlying Recall
The goal of this clinical trial is to examine how repeated memory retrieval changes visual representations in the brain in healthy adult participants.
- Trial name
- NCT07442266
- Testing
- Visual Memory Encoding and Retrieval Task During fMRI
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Brown University
Schizophrenia Cognition Autobiographical Memory Cognitive Remediation
Cognitive Remediation of Autobiographical Memory in Schizophrenia Using SenseCam®
The aim of the study is to assess the efficiency of SenseCam® in patients with schizophrenia by comparing two cognitive remediation methods of autobiographical memory.Patients and control participants will be invited to carry…
- Trial name
- RéMABSchiz (NCT02038465)
- Testing
- Questionary
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Huntington Disease, Autobiographical Memory
Autobiographical Memory, Future Thought, and Eye Movements in Huntington's Disease
Huntington's disease (HD) is a hereditary neurodegenerative disorder characterized by progressively worsening motor, cognitive, psychiatric, and behavioral deficits.
- Trial name
- MAMOC-MH (NCT07409597)
- Testing
- neuropsychological tests, Eye tracker use
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Schizophrenia, Episodic Memory Deficits
Testing Effect and Schizophrenia
When people are tested on a previously learned material, they will latter remember it better even when compared to a condition where they can re-study it.
- Trial name
- NCT02150174
- Testing
- Retrieval practice effect using word pairs and cued recall tests with feedback
- Where
- 2 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Child, Only, Narration
Effects of a Group EMDR Intervention on Narrative Complexity and Specificity of Autobiographical Memories: the Hug the Child Study (HTC)
Background and study aims: The Eye Movement Desensitization and Reprocessing Group Protocol with Children (EMDR-GP/C) was first developed by Korkmazlar following the Marmara earthquake in Turkey in 1999 and can be adapted for…
- Conditions
- Child, Only, Narration, Memory Dysfunction, Distress, Emotional
- Trial name
- HTC (NCT05319002)
- Testing
- Group EMDR
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pisa
Alzheimer Disease, Early Onset, Atypical Alzheimer's Disease
Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease
Alzheimer's disease (AD) is the leading neurodegenerative disease of aging characterized by multiple cognitive impairments. Given the recent failures of disease-modifying drugs, the current focus is on preventing or mitigating…
- Conditions
- Alzheimer Disease, Early Onset, Atypical Alzheimer's Disease, Logopenic Progressive Aphasia
- Trial name
- NCT04122001
- Testing
- Active, in-person HD-tDCS or active remote tDCS, Word List Learning Intervention (WordLLI)
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Aging
Breaking Sitting with High-intensity Interval Training for Brain Health
This trial will examine whether interrupting 3.5 hours of sitting every 30 min with 6 min high intensity interval training (HIIT) breaks compared to light intensity interval training (LIIT) will improve brain health in…
- Trial name
- HIIT2SITLess (NCT06243016)
- Testing
- High-Intensity Interval Training (HIIT) Breaks to Sitting, Light-Intensity Interval Training (LIIT) Breaks to Sitting
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Episodic Memory
Episodic Memory Integration and Interference
The purpose of this study is to assess how emotional memories integrate and interfere with one another over time. We will be using a multi-session experimental paradigm consisting of two encoding sessions and one retrieval…
- Trial name
- NCT05974371
- Testing
- emotional context similarity
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Boston College
Mild Cognitive Impairment
Improvement of Memory in Mild Cognitive Impairment
The Clinical Trial will systematically examine the feasibility of remote, caregiver-led tACS for older adults with memory deficits and evaluate whether repeated tACS leads to sustained improvement of neuronal activity and memory…
- Trial name
- NCT05708001
- Testing
- transcranial alternating current stimulation (tACS), high-density electroencephalography (hdEEG), Montreal Cognitive Assessment (MoCA)
- Where
- Switzerland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lucie Bréchet