Clinical trials: Memory, Short-Term
Resilience, Stress
Investigating Train the Trainer Delivery of Mindfulness-based Training
This project aims to evaluate the effectiveness of mindfulness training (MT) on cognitive and psychological factors when incorporated to the duty-day schedule of servicemembers (via proctored mindfulness practice).
- Trial name
- TTT (NCT03250156)
- Testing
- MBAT with proctored practice, MBAT with non-proctored practice
- Where
- 2 sites in United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Miami
Memory
Individualized Closed Loop TMS for Working Memory Enhancement
The study is investigating working memory brain states by using transcranial magnetic stimulation (TMS) in combination with functional magnetic resonance imaging (fMRI).
- Trial name
- NCT04402294
- Testing
- Functional Magnetic Resonance Imaging (fMRI), Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Menopause
Choline Dose Ranging in Postmenopausal Women
This study will use a randomized placebo-controlled trial to examine smaller doses of choline and whether a signal in the brain is detectable using fMRI.
- Trial name
- NCT06924541
- Testing
- Choline
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Julie Dumas
Age-associated Memory Impairment
TMS for Investigating Memory Facilitation
The aim of this study is to investigate the effects of Transcranial Magnetic Stimulation (TMS) following a Paired Associative Stimulation (PAS) protocol on the memorization capacity of elderly individuals.
- Trial name
- NCT05462782
- Testing
- Transcranial Magnetic Stimulation (TMS) Cone Coil
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Pediatric Obesity, Inhibition
Brain Mechanisms of Overeating in Children
The proposed research will follow healthy weight children who vary by family risk for obesity to identify the neurobiological and appetitive traits that are implicated in overeating and weight gain during the critical…
- Conditions
- Pediatric Obesity, Inhibition, Decision Making, fMRI
- Trial name
- RO1 (NCT03341247)
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Penn State University
Healthy Adult Participants
The Effects of Multiple Object Tracking And Mental Imagery On Tennis Performance
The goal of this clinical trial was to evaluate whether multiple object tracking and mental imagery training affect tennis performance, executive functions, anxiety, and psychophysiological variables in university students…
- Trial name
- MOT-MI (NCT07794228)
- Testing
- Multiple Object Tracking Training, Mental Imagery Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Halic University
Cognitive Aging
The Effects of Mixed Working Memory Training on Subsequent Training Gains Among Older Adults
While an intellectually active and socially integrated lifestyle shows promise for promoting cognitive resilience, the mechanisms underlying any such effects are not well understood.
- Trial name
- MixedWM (NCT05672771)
- Testing
- Different Mixed Condition (DM), Different Single Condition (DS), Same Task (ST) Practice Control
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Phenylketonurias
Remote Neurocognitive and Psychological Assessment in PKU
PKU is a rare autosomal recessive condition associated with disruption in dopamine synthesis. Although early diagnosis and treatment prevent the severe impairments associated with untreated PKU, individuals with early-treated PKU…
- Trial name
- NCT04943393
- Testing
- nointervention
- Where
- 2 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Sulpiride's Effect on Striatal BOLD Signal During Working Memory Gating, Interaction of Sulpiride, Average Reward Rate and Evidence Accumulation
Dopamine and Cognition
Rationale: To unravel the role of dopamine in gating of working memory, motivation and learning. Objective: The primary objective of this study is to isolate effects of blocking D2 receptor stimulation on gating of working…
- Conditions
- Sulpiride's Effect on Striatal BOLD Signal During Working Memory Gating, Interaction of Sulpiride, Average Reward Rate and Evidence Accumulation, Interaction of Sulpiride, Average Reward Rate and Cognitive Effort
- Trial name
- NCT05884671
- Testing
- Sulpiride 400 MG
- Where
- Netherlands
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Donders Centre for Cognitive Neuroimaging
Multiple Sclerosis
Patient Centered Outcomes Analysis for MS Using a Mobile Application
Multiple Sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) that can impact all aspects of nervous system function.
- Trial name
- NCT04281160
- Testing
- BeCare Mobile App
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- BeCare Link LLC
Aging, Physical Activity
Exercise Periodization and Older Adults
The present study aimed at investigating the effects of two different resistance training protocols - nonperiodized (NP) and daily undulating periodization (DUP) - on hemodynamic, morphofunctional and cognitive parameters of…
- Conditions
- Aging, Physical Activity, Sarcopenia, Cognitive Decline
- Trial name
- NCT03443375
- Testing
- Physical exercise
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Memory, Long-Term, Memory, Short-Term
Influence of Losartan and Diphenhydramine on Emotional and Cognitive Functions in Healthy Human Subjects
This project aims at identifying novel pharmacological targets for the treatment of memory disorders.
- Trial name
- LoDi-Basel (NCT01321021)
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Auditory Fatigue
Evaluation of Auditory Fatigue in Medical Regulation Assistants
Auditory monitoring of employees is currently based on pure-tone audiometry. However, this clinical examination does not prevent from deafness but established it a posteriori.
- Trial name
- EchoSam (NCT02384681)
- Testing
- Exposure to auditory fatigue
- Where
- France
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Transcranial Direct Current Stimulation, Working Memory
Transcranial Direct Current Stimulation Effect on Pain Threshold and Working Memory: Impact of Age and Protocol Type
Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation method which has great potential as an aid in the therapeutic management of neuropsychiatric disorders and chronic pain syndromes.
- Conditions
- Transcranial Direct Current Stimulation, Working Memory, Pain
- Trial name
- NCT04328545
- Testing
- Anodal tDCS on DLPFC, Anodal tDCS on M1
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Neurofeedback, Cognitive Training
Neurofeedback Removal of Emotional Information From Mind
This project will examine whether individuals can be trained, using real-time feedback about brain function during neuroimaging, to effectively remove thoughts from mind by providing them with a sense of what it feels like to…
- Conditions
- Neurofeedback, Cognitive Training, Memory, Short-Term, Functional Magnetic Resonance Imaging (fMRI)
- Trial name
- remtrain (NCT06460207)
- Testing
- fMRI neurofeedback
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Attention, Memory, Short-Term
Effectiveness of Modafinil in Improving Cognitive Performance of University Students
The purpose of this study is to determine whether modafinil is effective in the improvement of mnesic performance and executive functions of university students from high academic performance.
- Conditions
- Attention, Memory, Short-Term, Executive Function
- Trial name
- NCT01365897
- Testing
- Modafinil
- Where
- 2 sites in Chile
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Child Cancer Brain
MEDIR Medulloblastome
The medulloblastome is a tumour of the child relatively frequent usually sitting in the cerebellum and treated by surgery, radiotherapy and chemotherapy.
- Trial name
- MEDIR (NCT01197924)
- Testing
- IRMf Bold
- Where
- 8 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Brain Tumors
Working Memory Performance Among Childhood Brain Tumor Survivors
Children treated with radiation therapy for brain tumors are at risk for cognitive problems. These problems have typically been demonstrated on global cognitive measures including measures of intellectual functioning (IQ).
- Trial name
- NCT00693914
- Testing
- Series of tests/questionnaires
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- St. Jude Children's Research Hospital
Healthy Volunteers
Memory and Attention in Healthy Children
This project studies memory and attention in healthy children aged from 5 to 17 years. The processes investigated are short term memory (auditory and visual) and attention.
- Trial name
- MASK (NCT02858752)
- Testing
- Experience 1 : Auditory and Visual Discrimination, Experience 2 : Passive and Active Auditory Perception, Experience 3 : Visual Attention Training
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Executive Dysfunction
Causal Role of the Aperiodic Signal for Working Memory
Working memory (WM) is the ability to hold relevant information in mind in the absence of sensory input. The capacity for WM is a foundation for cognitive control and higher cognitive function more broadly.
- Trial name
- TRAS (NCT06126809)
- Testing
- Steep-tRAS, Flat-tRAS
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Florida State University