Clinical trials: Memory, Short-Term
Tobacco Use Disorder
Working Memory Training Combined With Transcranial Magnetic Stimulation in Smokers
Smoking remains the leading cause of preventable death in the United States, and current first-line treatments leave the majority of tobacco dependent individuals unable to quit.
- Trial name
- NCT03337113
- Testing
- Working Memory Training, repetitive Transcranial Magnetic Stimulation
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kent State University
Working Memory
Influence of Fampridine on Working Memory in Healthy Subjects
Proof-of-concept study on the effects of 10 mg fampridine (oral administration) on working memory in healthy participants. The hypotheses is that fampridine improves working memory performance.
- Trial name
- Fampyr_2020 (NCT04516603)
- Testing
- Fampridine SR
- Where
- Switzerland
- Volunteers
- healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Young Adults
Oscillatory Contributions to Working Memory and Attention
The objectives are articulated in the proposal's specific aims: Aim 1: To test the hypothesis that the cognitive control of unattended memory items (UMI) is implemented by the same frontoparietal mechanisms that control spatial…
- Trial name
- NCT03787134
- Testing
- working memory and attention
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Neuronal Mechanisms, Laminar Circuits
Clinical Study of How Information Flows Across the Human Cortical Sheet Layers (Laminae), Aiming to Discover Key Principles of Laminar Circuits and Information Flow for Complex Behavior.
This is a basic science study of a missing dimension of human brain function, how information flows the six layers of the brain.
- Trial name
- LamCircuits (NCT07073391)
- Testing
- Recording with laminar arrays
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Christopher I. Petkov
Hypoxia, Hypoxia Brain
Study of the Effects of Acute Exposure to Moderate Altitude Hypoxia on Prospective Memory.
The goal of this study is to investigate whether prospective memory, i.e., memory for delayed intentions, is impaired at moderate altitude (4,000m).
- Conditions
- Hypoxia, Hypoxia Brain, Hypoxia Altitude Simulation Test, Hypoxia in Healthy Individuals
- Trial name
- HYPRO (NCT07585227)
- Testing
- Hypoxia exposure, Oxygen administration, Air administration
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Healthy
Effect of Bacopa Monnieri on Working Memory and Cognitive Processing in Student
The purpose of this study is to determine the effect of Bacopa Monnieri on working memory and cognitive processing in student.
- Trial name
- NCT02931747
- Testing
- Bacopa Monnieri 300 mg/day, Bacopa Monnieri 600 mg/day
- Where
- Thailand
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Normal Physiology
Modulation of the Parieto-frontal Communication
Background: Research shows that the parietal and prefrontal areas of the brain are involved in short-term memory. Researchers want to look at the effects of transcranial magnetic stimulation (TMS) of these areas on short-term…
- Trial name
- NCT03434093
- Testing
- Transcranial Magnetic Stimulation (TMS), Working Memory Task
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Essential Tremor
Ventrointermediate Nucleus (VIM DBS) and Working Memory
This is part of a larger study for which participants have already completed memory and thinking tests. In this study, investigators are trying to learn how deep-brain stimulation affects memory skills in essential tremor (ET)…
- Trial name
- WMVIM (NCT00906412)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Healthy
Working Memory Quality of Attentional Templates
In this line of research, the researchers are examining a basic science question regarding the working memory representations underlying visual search using a positive template (looking for a target) or a negative template…
- Trial name
- NCT05863715
- Testing
- Visual Search Cue Type
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Lehigh University
Ageing
Attention and Memory Training With Video Games in Old Age
Neuroplasticity-based approaches seem very promising to maintain cognitive health in older adults and postpone the onset of cognitive-decline and dementia symptoms. The aims of this project are threefold: 1.
- Trial name
- AGEGAME (NCT02796508)
- Testing
- Experimental: Non-action video game training, Active Comparator: Non-cognitive video game training
- Where
- Spain
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Educación a Distancia
Cognitive Performance, Executive Function (Cognition)
Exploring the Cognitive Benefits of a Blackcurrant-Based Supplement in Normobaric Hypoxia
This study investigates the cognitive effects of Ārepa, a blackcurrant-based drink, under simulated high-altitude conditions (4,500m normobaric hypoxia for ~180 minutes).
- Conditions
- Cognitive Performance, Executive Function (Cognition), Working Memory, Hypoxia Induced Cognitive Impairment
- Trial name
- NCT07166835
- Testing
- Nootropics (ginkgo biloba, nicergoline, piracetam, or others)
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Drug Abuse, Prenatal Drug Exposure
Prenatal Drug Exposure: Effects on the Adolescent Brain and Behavior Development
Background: Recent research has suggested that prenatal exposure to drugs may affect specific brain processes, including working memory, stress response, and decision making.
- Trial name
- NCT01020669
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Attention-deficit/Hyperactivity Disorder
A Genome-wide Association Study on the Endophenotype of Spatial Working Memory in ADHD
Specific Aims: 1. To find the genetic variations associated with spatial working memory performance in patients with ADHD by using genome-wide association studies (GWAS); 2.
- Trial name
- NCT02710929
- Where
- Taiwan
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cognitive Decline, Healthy
The Effects of Attentional Filter Training on Working Memory
The investigators are interested in how attentional filter training/ distractor inhibition training could influence cognitive functions like working memory, executive control, problem solving, decision making and attentional…
- Conditions
- Cognitive Decline, Healthy, Age-related Cognitive Decline
- Trial name
- DIIN (NCT03228446)
- Testing
- filter training, memory training, no training (control)
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- German Center for Neurodegenerative Diseases (DZNE)
Autism
Effects of Hyperbaric Oxygen Therapy on Children With Autism
PURPOSE The purpose of this investigation is to evaluate the cognitive and behavioral effects of Hyperbaric Oxygenation Therapy in children who present with a diagnosis of autism spectrum disorder. HYPOTHESIS 1.
- Trial name
- NCT00406159
- Testing
- Hyperbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Thoughtful House
Healthy, Amusia, Congenital
Auditory Deficits in Congenital Amusia (AMUSIE CONGENITALE)
The project studies auditory deficits in congenital amusia at the behavioral and neurophysiological levels. The auditory processes investigated are pitch discrimination, short-term memory, sound-induced emotions.
- Trial name
- NCT03094624
- Testing
- Neuropsychological and neurophysiological tests, Experiment 1, Experiment 2
- Where
- France
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Healthy Adults
Characterizing the Synergistic Effects of Physical and Cognitive Training on Attention and Working Memory
The primary goal of this project is to evidence potential synergistic benefits on cognitive control processes using a video game ("Body-Brain Trainer", or BBT) that integrates cognitive and physical challenges in a complimentary…
- Trial name
- BBT (NCT03032796)
- Testing
- Body-Brain Trainer, Body Trainer, Brain Trainer
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Schizophrenia
Pharmacologically-augmented Cognitive Therapies (PACTs) for Schizophrenia.
This application seeks renewed support for MH59803, "Dopaminergic substrates of startle gating across species," to extend a clear path of "bench-to-bedside" progress towards a critical paradigm shift in therapeutic models for…
- Trial name
- NCT02634684
- Testing
- Dextroamphetamine
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
First Episode Psychosis (FEP), Psychosis
Early Psychosis: Investigating Cognition
The project aims to explore changes in brain chemistry in individuals who have recently experienced psychosis. Recent research suggests that chemicals in the brain, specifically one called glutamate, may behave differently in…
- Trial name
- EPIC (NCT07196423)
- Testing
- Transcranial direct current stimulation (tDCS), Magnetic Resonance Imaging
- Where
- United Kingdom
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Schizophrenia
The Effect of Repetitive Transcranial Magnetic Stimulation (rTMS) on Working Memory
Deficits in working memory (WM) performance are the most significant cognitive impairments in schizophrenia (SCZ). It has also been shown that WM performance is contingent on the cortex synchronization, a process that relies on…
- Trial name
- NCT01494623
- Testing
- repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health