Clinical trials: Memory Functions
Cognition, Cardiometabolic Risk Factors
Trial of Pistachio Consumption in Older Adults
The goal of this study is to evaluate whether a pistachio-enriched diet leads to changes in cognitive function, cardiometabolic risk factors, and life satisfaction in older adults over a 6-month period.
- Conditions
- Cognition, Cardiometabolic Risk Factors, Life Satisfaction
- Trial name
- NCT06992544
- Testing
- Pistachio-enriched diet, Usual diet
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Dementia
BELIDE: Better Living With Non-memory-led Dementia
Around 48 million people worldwide 1 live with dementia, of whom 3.9 million start with symptoms before the age of 65 (young-onset dementia).
- Trial name
- BELIDE (NCT06241287)
- Testing
- Better Living with Non-memory led Dementia programme, Waiting list
- Where
- United Kingdom
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- University College, London
Alzheimer Disease, Late Onset, Mild Cognitive Impairment
Time-in-bed Restriction in Older Adults With Sleep Difficulties With and Without Risk for Alzheimer's Disease
Dementia caused by Alzheimer's disease affects approximately 5.6 million adults over age 65, with costs expected to rise from $307 billion to $1.5 trillion over the next 30 years.
- Conditions
- Alzheimer Disease, Late Onset, Mild Cognitive Impairment, Sleep, Cognitive Change
- Trial name
- ALPS (NCT05138848)
- Testing
- Time in Bed Restriction, Sleep Schedule
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Healthy
Hippocampal and Frontoparietal Development and Inference
The goal of this clinical trial is to test if an intervention used to manipulate memory and inference can improve our understanding of how brain development supports these abilities in healthy adolescent and adult volunteers.
- Trial name
- NCT07199907
- Testing
- Associative Inference, Probabilistic Inference
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Sleep, Consolidation
Reactivating Specific Memories During Sleep in Conjunction with a Suppression Context
Forgetting is often perceived as the inability to retain information, but in fact at least some memory deterioration is due to active suppression processes, that are behaviorally adaptive.
- Trial name
- NCT04702750
- Testing
- Targeted memory reactivation (odors), Targeted memory reactivation (sounds)
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Dopamine Activity, Episodic Memory Consolidation
Dopaminergic Modulation of Cognition and Psychomotor Function
A recent study at our lab showed increased episodic memory consolidation and response readiness after treatment with methylphenidate in healthy volunteers. The investigators seek to replicate and extend these findings.
- Conditions
- Dopamine Activity, Episodic Memory Consolidation, Response Preparation
- Trial name
- NCT01218425
- Testing
- Methylphenidate 40 mg, Levodopa/carbidopa 125 mg, Domperidon 10 mg
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Cardiac Arrest, Cognitive Impairment
Modifying Working Memory With Brain Stimulation
The investigators want to investigate the effect of rTMS on working memory measured by the N-back task. This is a single case experimental design, ABAB.
- Trial name
- BROCA-NIBS (NCT06119620)
- Testing
- intermitted theta burst stimulation
- Where
- Netherlands
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Maastricht University
Sarcopenia, Memory Loss
Effects of Multidomain Training of Health With Aging (Train-Old)
The current study aims to determine the effect of a multidomain intervention (physical fitness, motivational and cognitive training) on body composition, sarcopenia, cardiovascular health, physical fitness, functional capacity…
- Conditions
- Sarcopenia, Memory Loss, Muscular Atrophy, Cardiovascular Diseases
- Trial name
- Train-Old (NCT05481346)
- Testing
- Multidomain training
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad de Almeria
Skeletal Muscle Physiology
Muscle Memory After Treatment With Anabolic Substance Clenbuterol and Resistance Training in Humans
The purpose of the project is investigate muscle memory and underlying mechanisms in humans following resistance training and use of the anabolic substance clenbuterol.
- Trial name
- NCT05692856
- Testing
- Clenbuterol
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Morten Hostrup, PhD
Healthy Adolescents
Double-Blind Randomized Controlled Trial for the Evaluation of a Novel Adaptive Attention Training in Healthy Adolescents
This project will evaluate the neuro-cognitive outcomes of a novel, adaptive attention training in a healthy adolescent population.
- Trial name
- NCT03213613
- Testing
- Adaptive Attention Training, Active Control, Low-dose Adaptive Attention Training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Breast Cancer, Memory Disorders
Study of the Functioning of Prospective Memory in Breast Cancer and the Influence of Sleep
The results of this study will contribute to a better understanding of prospective memory deficit processes in breast cancer in relation to sleep disorders frequently reported in this pathology.
- Trial name
- PROSOM-K (NCT03420105)
- Testing
- Neuropsychological, psycho-pathological and quality of life assessments, Hormonotherapy
- Where
- 2 sites in France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Centre Francois Baclesse
Aging
The Entorhinal Cortex and Aerobic Exercise in Aging
The overall goal of this study is to examine how regular exercise affects brain function, spatial memory, and virtual navigation. Participation in this research study will take approximately 4 months.
- Trial name
- ECE (NCT02775760)
- Testing
- Cardiovascular endurance, Strength, balance, and flexibility
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Boston University
Cannabis, Psychotic Disorders
Cannabinoids, Learning, and Memory
The overarching goal of this study is to characterize the effects of cannabinoids on working and episodic memory.
- Trial name
- THC-Memory (NCT02407808)
- Testing
- THC
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yale University
Parkinson Disease
Triggering Motor Memory Consolidation in PD: Complex Practice of Fine Motor Tasks and Brain Activity During Learning
Parkinson's disease (PD) is characterized by severe motor symptoms, including upper limb dysfunction, that is only partially alleviated by medication.
- Trial name
- NCT04269590
- Testing
- Dual Task (DT) training, Single Task (ST) training
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Invasive Meningococcal Disease
Can we Reduce the Number of Vaccine Injections for Children?
This open label randomised controlled study will evaluate the induction of immunity following varying schedules of vaccination with glyco-conjugate Neisseria meningitidis serogroup C (MenC) vaccines in infancy.
- Trial name
- MALTA (NCT01129518)
- Testing
- Glyco-conjugate Neisseria meningitidis serogroup C (MenC) vaccine, Routine schedule immunisations except monovalent MenC vaccine
- Where
- United Kingdom
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Memory, Delayed
Neural Correlates of Real World Spatial Navigation in Humans
The purpose of this study is to understand the neural mechanisms that support real world spatial navigation in humans using deep brain recordings and stimulation during virtual reality (VR), augmented reality, and real world…
- Trial name
- NCT04874220
- Testing
- Deep Brain Stimulation, Memory and spatial navigation tasks, Physiological Signals
- Where
- 2 sites in United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Duke University
Mild Cognitive Impairment, Subjective Cognitive Decline
Thinking About Memory: How Confident Are You in Your Memory, and Does it Change With Age?
Memory and our own beliefs and confidence in our ability to remember are important for our daily lives. For example, low confidence may hold us back from doing certain tasks, whereas misplaced high confidence in our memories may…
- Trial name
- NCT06539403
- Testing
- Memory tasks
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- King's College London
Cognitive Change, Mood
Turmeric for Memory Impairment and Cognition
The objective of the study is to test the capacity of acute and chronic supplementations of Turmipure GOLD® to improve cognitive performance in healthy aging
- Conditions
- Cognitive Change, Mood, Stress
- Trial name
- TURMEMIC (NCT04860050)
- Testing
- Turmipure Gold®
- Where
- Ireland
- Volunteers
- 568 people, healthy volunteers welcome
- Sponsor
- Givaudan France Naturals
Multiple Sclerosis
Patient Centered Outcomes Analysis for MS Using a Mobile Application
Multiple Sclerosis (MS) is a demyelinating disease of the central nervous system (CNS) that can impact all aspects of nervous system function.
- Trial name
- NCT04281160
- Testing
- BeCare Mobile App
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- BeCare Link LLC
Narrative Exposure Therapy, Treatment as Usual
Effectiveness of Narrative Exposure Therapy Among Refugee Children and Adolescents
This study aims to understand how war trauma affects children's and adolescents' memory functions and mental health, and whether Narrative Exposure Therapy is effective in enhancing optimal memory functions and alleviating mental…
- Trial name
- NCT02425280
- Testing
- Narrative Exposure Therapy, Treatment as Usual
- Where
- 3 sites in Finland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tampere University
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