Clinical trials: Memory Functions
Subjective Cognitive Decline (SCD)
Polyamine-enriched Diet in Elderly Individuals With Subjective Cognitive Decline
The overall objective of this study is to examine the effect of polyamine supplementation on cognitive performance and further characterization of individuals with subjective cognitive decline.
- Trial name
- SmartAge (NCT03094546)
- Testing
- Polyamine
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Alzheimer's Disease, Impaired Cognition
Predictive Value of Cognitive Tests Performed for the Diagnosis of Alzheimer's Disease and Related Disorders
The purpose of this study is to determine the predictive value of standardized cognitive tests performed in health examination centres for the diagnosis of Alzheimer's disease and related disorders among adults aged 65 years and…
- Conditions
- Alzheimer's Disease, Impaired Cognition, Memory Disorders
- Trial name
- EVATEM (NCT01316562)
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Cognitive Change
Understanding Individual Differences in Working Memory Training and Transfer in Older Adults
The present study investigates how individual differences in cognitive processing contribute to the efficacy of working memory training programs in an older adult population.
- Trial name
- NCT05396586
- Testing
- N-back, Span, Multisensory
- Where
- 2 sites in United States
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- Northeastern University
Memory Disorders
AIT-082 Phase 1B Study
AIT-082 is a novel small molecule that crosses the blood-brain barrier to enhance nerve function by increasing levels of neurotrophic growth factors and encouraging nerve sprouting in the brain.
- Trial name
- NCT00000180
- Testing
- AIT-082
- Where
- 4 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Pediatric Obesity, Behavior and Behavior Mechanisms
Neuro-cognitive Impact of Juvenile Obesity
Recent studies indicate that obese teenagers exhibit memory disturbances. Adolescence represents a crucial period in the development of the hippocampus and the amygdala, necessary for the implementation of memory and emotional…
- Conditions
- Pediatric Obesity, Behavior and Behavior Mechanisms, Emotions
- Trial name
- OBETEEN (NCT03776513)
- Testing
- an MRI examination
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Memory Impairment, Alzheimer's Disease
Roflumilast and Donepezil to Reverse Scopolamine Induced Cognitive Deficits in Healthy Adults
The purpose of this study is to determine whether scopolamine-induced cognitive impairment is attenuated by the administration of roflumilast in combination with donepezil.
- Trial name
- NCT02051335
- Testing
- Roflumilast, Donepezil, Scopolamine
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Healthy Adults With Subjective Memory Complaints
Effects of HX106 on Improvement in Cognitive-Bio-Markers of Memory Function
The objectives of the current study are to evaluate the efficacy and safety of HX106 in healthy adults with subjective memory complaints for improving cognitive and neurobiolgoical markers of memory.
- Trial name
- NCT01956097
- Testing
- HX106 590mg, HX106 1180mg
- Where
- South Korea
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ewha Womans University
Alzheimer Disease, Memory Disorders
Alzheimer's Disease Prevention Trial
This is a three-year study to determine if estrogens can prevent memory loss and Alzheimer's disease in women with a family history of Alzheimer's disease.
- Trial name
- NCT00000176
- Testing
- Estrogen, Estrogen and Progesterone
- Where
- 22 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Aging
Improvement in Memory With Plasticity-Based Adaptive Cognitive Training (IMPACT)
The primary objective of this study is to evaluate the effects of a computer-based training program on the memory and cognitive abilities of mature individuals undergoing healthy aging.
- Trial name
- IMPACT (NCT00283010)
- Testing
- Computerized Plasticity-Based Adaptive Cognitive Training, Educational DVDs
- Where
- United States
- Volunteers
- 487 people, healthy volunteers welcome
- Sponsor
- Posit Science Corporation
Parkinson Disease, Memory Impairment
Dopaminergic Mechanism of Memory Impairment in Parkinson's Disease
The cognitive impairment of Parkinson's disease is non amnestic, which is characterized by working memory impairment and executive dysfunction.
- Trial name
- NCT04968613
- Testing
- Madopar monotherapy, senfrol monotherapy
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Smoking Cessation, Smoking, Cigarette
Pictorial Warning Labels & Memory for Relative & Absolute Cigarette Health-risk Information Over Time in Adult Smokers
Pictorial cigarette warning labels (PWLs) are thought to increase risk knowledge, but experimental research has not examined PWLs' longer term effects on memory for health risks.
- Trial name
- NCT03499340
- Testing
- text-only PWL, low arousal graphic PWL, high arousal graphic PWL
- Where
- United States
- Volunteers
- 3,213 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Malaria
Computerized Cognitive Rehabilitation in Children After Severe Malaria
Brain training exercises will be provided to children who survived an episode of severe malaria. These children will be given assessments for cognition, behaviour and executive functions before and after the brain training…
- Trial name
- CM_CCRT (NCT01743417)
- Testing
- Computerised cognitive rehabilitation training
- Where
- Uganda
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Makerere University
Cognition, Cognition Disorders
Establishing Normal Cognitive Test Scores for Adults Using a Voice-Enabled Digital Testing Platform Across the Lifespan
Trial weblink: https://www.memoryexam.com/job/norms/ Participants enrolled in this study will complete a single-session, non-invasive, computerized cognitive assessment administered through a secure, web-based digital platform.
- Conditions
- Cognition, Cognition Disorders, Cognition - Other, Dementia
- Trial name
- NCT07763392
- Testing
- Voice-based Cognitive Testing
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- The Neurology Center of Southern California
Memory
Memory and Mental Health in Aging
A comparison of memory training with and without donepezil.
- Trial name
- NCT02988908
- Testing
- Donepezil
- Where
- United States
- Volunteers
- 198 people, healthy volunteers welcome
- Sponsor
- Stanford University
ADHD, Dyslexia
Computerized Working Memory Training
Prior research has found that children with attention-deficit hyperactivity disorder (ADHD) and reading difficulties (RD) are at an elevated risk of developing further cognitive deficits and developmental challenges.
- Trial name
- NCT06567444
- Testing
- Working memory intervention
- Where
- Hong Kong
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Education University of Hong Kong
Healthy
Propofol's Hypnotic and Memory Effects
The purpose of this study is to relate changes in the blood flow in your brain which are measured using magnetic resonance imaging (MRI) to temporary changes in your memory and level of sleepiness while receiving the drug…
- Trial name
- NCT00576615
- Testing
- propofol
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Speech, Consolidation
Sensory Basis of Speech Motor Learning
These studies test the hypothesis that sensory areas of the brain participate in the consolidation of speech motor memory by using transcranial magnetic stimulation to suppress activity in somatosensory and auditory cortex…
- Trial name
- NCT04497428
- Testing
- Adaptation, cTBS
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yale University
Attention Deficit Hyperactivity Disorders
Low-dose vs. Normal-dose Psychostimulants on Executive Functions in Individuals With ADHD
This double-blind crossover study aims to compare cognitive performance (e.g., working memory, selective attention and cognitive flexibility) of children ages 6-18 years diagnosed with ADHD of the combined type (ADHD-C) or…
- Trial name
- NCT02167048
- Testing
- Psychostimulants
- Where
- Canada
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Mild Cognitive Impairment
Cognitive Ability Training in Seniors
This study investigates the beneficial effects of prefrontal brain stimulation (with transcranial direct current stimulation [tDCS]) during working memory training in seniors with subjective memory impairments.The…
- Trial name
- CATS (NCT02587338)
- Testing
- Verum tDCS
- Where
- Germany
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Wuerzburg University Hospital
Mild Cognitive Impairment (MCI) Amnestic, Mild Cognitive Impairment
Mental Strategy Training in Mild Cognitive Impairment
This study aims to reduce hippocampal activity in people at high risk of developing Alzheimer's disease (AD) and aims to examine whether this improves their episodic memory performance.
- Trial name
- NCT07718945
- Testing
- Mental Strategy Training
- Where
- Switzerland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Jessica Peter
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