Clinical trials: Men
Cancer of the Prostate
Decision Impact Trial of the ExoDx Prostate (IntelliScore)
The purpose of this research study is to investigate the utility of a validated urine test which predicts the likelihood of high grade prostate cancer on an initial prostate biopsy.
- Trial name
- NCT03235687
- Testing
- ExoDx Prostate (IntelliScore)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Exosome Diagnostics, Inc.
Healthy
Influence of Repetitive Transcranial Magnetic Stimulation (rTMS) Challenge on Cognitive and Functional Magnetic Resonance Imaging Markers in Healthy Subjects
Episodic and working memory processes are the most affected cognitive domains in Alzheimer's Disease (AD) and its early stage, Mild Cognitive Impairment (MCI).
- Trial name
- NCT01490021
- Testing
- rTMS/Active TBS
- Where
- Spain
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Qualissima
Muscle Soreness
The Effects of Swedish Massage and Manual Lymph Drainage on Muscle Fatigue
12 healthy men aged 18-30 will be included in the study. Participants will be selected from students who regularly train and do active sports at the Faculty of Sports Sciences. All participants will do nordic hamstring exercise.
- Trial name
- NCT06112899
- Testing
- Nordic Hamstring Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
PRE-HYPERTENSION
Cardiovascular Effects of Purple-Fleshed Potatoes
This study is being done to evaluate the effect on cardiovascular biomarkers and anthocyanin-derived plasma metabolites of Peruvian native purple-fleshed potato consumed over a 4-week period by prehypertensive men ages 18-40…
- Trial name
- NCT07734948
- Testing
- Purple flesh potato, White flesh potato
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigacion Nutricional, Peru
Hiv, Chlamydia
Randomized Trial of an HIV Prevention and Relationship Education Program for Young Male Couples
Young gay, bisexual, and other men who have sex with men (YMSM) are the only risk group in which rates of new HIV infections are on the rise.
- Conditions
- Hiv, Chlamydia, Gonorrhea, Relation, Interpersonal
- Trial name
- 2GETHER (NCT03186534)
- Testing
- 2GETHER, Positive Affect Enhancement
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Northwestern University
HIV
Reaching the Last 20% (the Pamoja Kwa Afya Study)
This cluster randomized controlled trial will test whether the provision of multiple oral fluid-based HIV self-test kits to women who sell sex (WSS) to secondarily distribute to their male partners who purchase sex can promote…
- Trial name
- NCT05882916
- Testing
- HIV self-testing, Behavioral economic 'nudges'
- Where
- Kenya
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Sue Napierala
Male Contraception, Semen Volume
Effects of NLS-133, a Potential Non-Hormonal "On-Demand" Male Contraceptive
NLS-133-CLIN001 is a Phase 2a study designed to assess the safety, tolerability, and effects of NLS-133 (combination of two FDA-approved agents) compared to an active control (FDA-approved pharmacologic agent) or placebo on semen…
- Conditions
- Male Contraception, Semen Volume, Sperm Motility
- Trial name
- NCT07393334
- Testing
- NLS-133, Active Comparator #1
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Next Life Sciences
Sexual Dysfunction, Endothelial Dysfunction
Effects of Diet-induced Weight Loss in Obese Men
This study aims to compare the efficacy of a partial meal replacement diet with a conventional diet, for inducing weight loss and improving metabolic and inflammatory profile, endothelial function, erectile function, sexual…
- Conditions
- Sexual Dysfunction, Endothelial Dysfunction, Quality of Life, Inflammation
- Trial name
- NCT01554865
- Testing
- Optifast, Conventional diet counseling
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Changi General Hospital
Pain
Attenuation of Pain in Men and Women
The purpose of this study is to examine opioid and endocannabinoid mechanisms of exercise-induced analgesia in men and women.
- Trial name
- NCT01220414
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Healthy Young Men, Healthy Young Women
Characterization of the Plasma Metallomic Profile to Acute Exercise in Healthy Men and Women (METALEXO)
Among the various trace elements playing a key role in physical performance, iron is probably one of the most studied in the last 30 years.
- Trial name
- METALEXO (NCT05718752)
- Testing
- Maximal incremental exercise test, 30-min submaximal exercise test
- Where
- France
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Rennes 2
Nocturia
Behavior and Exercise Versus Drug Treatment in Men With Nocturia (BEDTiMe)
Nocturia, waking at night from sleep to void, is a prevalent and troublesome symptom. Treatment with an alpha-adrenergic antagonist medication (α-blockers) is a standard therapy for LUTS in men, but α-blockers offer only limited…
- Trial name
- BEDTiMe (NCT00824200)
- Testing
- Behavioral, tamsulosin (alpha-adrenergic antagonist medication)
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Atlanta VA Medical Center
Obesity, Weight Loss
Effects of Adding L-BAIBA to Exercising Adult Overweight and Obese Men and Women
Beta-amino isobutyric acid (BAIBA) is a myokine produced in skeletal muscle and has been shown to impact how our body metabolizes fuel.
- Conditions
- Obesity, Weight Loss, Weight, Body, Cardiometabolic Syndrome
- Trial name
- LBC (NCT05775016)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Lindenwood University
Healthy
A Study of the Effects of Erythromycin on the Pharmacokinetics of Relugolix, Estradiol, and Norethindrone in Healthy Postmenopausal Women and on the Pharmacokinetics of Relugolix in Healthy Adult Men
This is a two-part, open-label, fixed-sequence, two-period crossover drug interaction study to assess the potential effects of erythromycin on the pharmacokinetics of relugolix, estradiol (E2), and norethindrone (NET) in healthy…
- Trial name
- NCT04714554
- Testing
- Relugolix/E2/NETA FDC, Relugolix, Erythromycin
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Myovant Sciences GmbH
Hypogonadism, Male
Single-Dose Pharmacokinetics of Oral Testosterone Undecanoate With and Without Concomitant Inhibition of UGT2B17
This study will be performed in normal men whose endogenous testosterone production has been temporarily suppressed by the administration of a single dose of 120 mg of the oral GnRH antagonist Relugolix, which is approved for the…
- Trial name
- OralT12 (NCT06312761)
- Testing
- Relugolix 120Mg Tab, Curcumin, Testosterone Undecanoate 237 MG Oral Capsule
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Washington
Healthy
A Study in Healthy Men to Find the Best Formulation for Once Daily Intake of Nintedanib
The main objective of this trial is to assess single dose drug exposure of several newly developed formulation prototypes of Nintedanib compared to Ofev® following oral administration.
- Trial name
- NCT05262751
- Testing
- Ofev®, Nintedanib formulation 1, Nintedanib formulation 2
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
ABG Oxidative Stress Study Protocol-1
This is a proof of concept study that evaluates the response to oxidative stress in healthy men after taking plant concentrates.
- Trial name
- NCT02213523
- Testing
- Plant concentrate A, Plant concentrate B, Plant concentrate C
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Access Business Group
Healthy
Study Evaluating FXR-450 in Healthy Japanese Men
The primary purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of a single dose of FXR-450 in healthy Japanese men.
- Trial name
- NCT00509756
- Testing
- FXR-450
- Where
- Japan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Spermatogenesis and Semen Disorders, Infertility, Male
Evaluation of FPT-20 for the Treatment of Spermatogenesis and Semen Disorders
This clinical study aims to evaluate the efficacy and safety of a novel, natural-derived formulation (FPT-20) in supporting spermatogenesis.
- Trial name
- NCT05399212
- Testing
- FPT-20
- Where
- Vietnam
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Trieu, Nguyen Thi, M.D.
Contraception
Oral Androgens in Man-4: (Short Title: Oral T-4)
The protocol was designed to address the hypothesis that oral testosterone enanthate plus dutasteride can suppress the secretion of LH and FSH after four weeks of administration.
- Trial name
- NCT00399165
- Testing
- Testosterone Enanthate, Dutasteride
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Washington
Healthy
A Study in Healthy Men to Measure the Amount of BI 425809 in the Blood When Taken as a Tablet
The primary objective of this trial is to investigate the absolute oral bioavailability of BI 425809 administered as tablet (Test, T) compared to [C-14]-BI 425809 administered as intravenous microtracer (Reference, R).
- Trial name
- NCT03783000
- Testing
- BI 425809, [C-14]-BI 425809
- Where
- Netherlands
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
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