Clinical trials: Meniscal Injuries
Repair of Meniscal Injury
Porous Tissue Regenerative Silk Scaffold for Human Meniscal Cartilage Repair
The REKREATE project will be an international, multi-centre, non-randomised, prospective single-arm pivotal study. All study patients will receive the FibroFix™ Meniscus scaffold following the provision of informed consent.
- Trial name
- REKREATE (NCT02732873)
- Testing
- FibroFix Meniscal Scaffold
- Sponsor
- Orthox Limited
Partial Meniscal Loss, Lateral Meniscus Partial Loss
Partial Meniscal Replacement with Spongioflex®
The purpose of this investigator-initiated trial is to evaluate whether the novel graft can prevent/reduce the disadvantages of the previously used replacement materials and shows better results than the group of patients, which…
- Conditions
- Partial Meniscal Loss, Lateral Meniscus Partial Loss, Medial Meniscal Partial Loss, Meniscus Lesion
- Trial name
- NCT06775197
- Testing
- partial meniscal replacement with Spongioflex®
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Maria-Josef-Hospital Greven
Meniscus Lesion, Meniscus Disorder
Dynamic Ultrasonography VS MRI in the Evaluation of Meniscal Lesions in Patients With an Indication for Arthroscopy
This is a diagnostic, open-label, single-center interventional study. This study aims to evaluate the diagnostic accuracy of dynamic ultrasonography for meniscal injuries in patients with an indication for arthroscopy, and to…
- Conditions
- Meniscus Lesion, Meniscus Disorder, ACL Injuries
- Trial name
- NCT06159153
- Testing
- Dynamic Ultrasonography assessment
- Where
- Italy
- Volunteers
- 8 people
- Sponsor
- Istituto Ortopedico Rizzoli
Meniscus Lesion
Sterile Allogeneic Spongioflex® Allograft as Partial Meniscal Replacement After Incomplete Meniscal Loss
The goal of this clinical trial is to learn if partial meniscal replacement can prevent or postpone total meniscal replacement, in adult patients (female/male) with partial meniscal loss.
- Trial name
- NCT06376422
- Testing
- Spongioflex®, non-operated
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Sven Behrendt
Tibial Meniscus Injuries, Osteoarthritis, Knee
Autologous, Micro-fragmented Adipose Tissue for Meniscal Tears
The menisci of the knee are essential fibro-cartilaginous structures that contribute in static weight bearing, distributing compressive forces during joint movement, joint lubrication, joint stabilization, and proprioception.
- Trial name
- NCT03714659
- Testing
- Lipogems
- Volunteers
- 20 people
- Sponsor
- New Jersey Regenerative Institute, LLC
Other Tear of Medial Meniscus, Current Injury
Initial Safety Evaluation of FibroFix™ Meniscus
Initial evaluation of safety and performance of FibroFix™ Meniscus scaffold
- Trial name
- NCT02205645
- Testing
- FibroFix™ Meniscus scaffold
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- Orthox Limited
ACL Injury, Meniscal Injuries
Intraoperative Energy Expenditure During ACL Reconstruction Surgery
This prospective observational study evaluates the intraoperative energy expenditure of the surgeon during anterior cruciate ligament reconstruction procedures.
- Trial name
- NCT07683247
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- ASL Lecce
Knee Medial Meniscus Tears, Meniscus Lesion
Predictors of Early Success From Circumferential Compression STITCH Meniscal Repairs
This is a retrospective study of meniscal tear repairs at least one-year post repair status. All patients were treated with Ceterix NovoStitch devices.
- Conditions
- Knee Medial Meniscus Tears, Meniscus Lesion, Meniscus; Rupture, Bucket Handle, Meniscus Disorder
- Trial name
- STITCHRetro (NCT03097744)
- Testing
- Ceterix NovoStitch
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Smith & Nephew, Inc.
Osteoarthritis, Knee, Knee Injuries
Impact of Mulligan Squeeze Technique on Meniscal Derangement in Knee Osteoarthritis Patients
The objective of this study is to find out the effects of Mulligan's Squeeze technique added as a complementary treatment to the conventional physiotherapy for the management of meniscal derangement in knee osteoarthritis…
- Conditions
- Osteoarthritis, Knee, Knee Injuries, Meniscus; Derangement, Meniscus Tear
- Trial name
- NCT06391047
- Testing
- Mulligan's Squeeze Technique - manual therapy, Conventional Physiotherapy
- Where
- Pakistan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Faisalabad
Knee Injuries
Meniscal Root Tears: Evaluation Using an Ultrahigh MRI
Meniscal root tears have been recently recognized to be one of the most common causes for the progression of arthritis in relatively young patients.
- Trial name
- NCT05088525
- Testing
- MRI
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Twin Cities Orthopedics
Microfractures, Meniscus Tear
The Effectiveness of the Microfracture Technique in the Meniscal Healing
Meniscus injuries are a very common cause of knee pain. The meniscus is a semilunar fibrocartilage structure found on the medial and lateral sides of the knee.
- Trial name
- NCT05799196
- Testing
- Microfracture
- Where
- Indonesia
- Volunteers
- 62 people
- Sponsor
- Hasanuddin University
Blood Flow Restriction and Low-Intensity Resistance Training, Meniscal Injuries
Blood Flow Restriction Training After Meniscus Surgery
This study was conducted to investigate the effects of combined low-intensity resistance exercise with blood flow restriction (BFR-LIRE) on muscle strength, pain, and fear of movement in individuals who had undergone…
- Trial name
- NCT07299461
- Testing
- Traditional physical therapy exercises and physical therapy modalities, Traditional physical therapy exercises and physical therapy modalities + low-intensity resistance exercise with blood flow restriction (BFR-LIRE)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Uskudar University
Meniscus Tear, Tibial
Operative vs Non-operative Management of Posterior-medial Meniscal Root Tears: A Randomized Multicenter Trial (RCT)
The purpose of this study is to determine differences in pain, functional patient reported outcomes, and objective imaging parameters following non-operative and meniscus root repair treatment.
- Trial name
- NCT05985772
- Testing
- Non-Operative Pain Management, Operative treatment arm will undergo transtibial medial meniscus root repair within 3 weeks of enrollment
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Rush University Medical Center
Knee; Injury, Meniscus (Lateral) (Medial), Meniscus Tear
Clinical Efficacy of Exosome in Degenerative Meniscal Injury
Comparison of intra-articular administration of synovial fluid-derived mesenchymal stem cells-derived exosomes with synovial fluid-derived mesenchymal stem cells on the same patient.
- Conditions
- Knee; Injury, Meniscus (Lateral) (Medial), Meniscus Tear, Meniscus Lesion, Meniscus; Degeneration
- Trial name
- KNEEXO (NCT05261360)
- Testing
- SF-MSC-EX, SF-MSC
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Eskisehir Osmangazi University
ACL-injury
Influence of Injury to the Kaplan Fibers in Adult and Pediatric Patients With ACL Injury
The goal of this [type of study: observational study] is to [detect concomitant KF and ALL injury in knees with ACL injury using MRI in both adult and pediatric patients and compare the effect of KF injury and multiple risk…
- Trial name
- NCT06002308
- Testing
- Age
- Where
- China
- Volunteers
- 540 people
- Sponsor
- Sichuan Province Orthopetic Hospital
Meniscus Rupture, Meniscus Injury
Surgical Outcome After Displaced Bucket-handle Meniscal Lesions - Repair Versus Partial Meniscectomy
The menisci of the knee joint are structures composed of cartilage and connective tissue, whose primary functions are to stabilize the joint and distribute weight across joint surfaces.
- Conditions
- Meniscus Rupture, Meniscus Injury, Osteoarthritis of Knee
- Trial name
- NCT07079254
- Testing
- Meniscus suture, Partial meniscectomy
- Where
- 2 sites in Sweden
- Volunteers
- 300 people
- Sponsor
- Region Skane
Chronic Meniscal Injury
Mesenchymal Stromal Cells for Degenerative Meniscus Injury
The present proposal has the objective to assess whether the addition of autologous ex vivo expanded mesenchymal stromal cells (XCEL-M-ALPHA) to the conventional meniscal injury rehabilitation program is contributing in creating…
- Trial name
- NCT02033525
- Testing
- XCEL-M-ALPHA and standard rehabilitation, Rehabilitation
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Banc de Sang i Teixits
Knee Injuries
Dynamic Contrast-Enhanced Fluorescence Arthroscopy of Meniscus Pilot
Single-center pilot prospective observational study to determine feasibility of assessing meniscal tissue vascularity using dynamic contrast-enhanced fluorescence arthroscopy
- Trial name
- NCT05072717
- Testing
- Perfusion with Indocyanine green
- Where
- United States
- Sponsor
- Dartmouth-Hitchcock Medical Center
Meniscus Tear, Tibial
Diagnostic Value of Weight Bearing CT for Detecting Meniscal Tears
This observational study will compare the clinical value of weight-bearing CT arthrography (WBCTa) with that for MRI in evaluating meniscal and cartilage lesions of the knee joint.
- Trial name
- NCT04430829
- Testing
- Weight-Bearing CT arthrography, Knee MRI
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Kansas Medical Center
Meniscal Tears
Meniscal Repair Augmented With Leukocyte-Poor Platelet-Rich Plasma: A Prospective Comparative Clinical Study
This prospective, randomized, comparative clinical study will evaluate the clinical and functional outcomes of meniscal repair augmented with intraoperative intralesional leukocyte-poor platelet-rich plasma (LP-PRP) compared with…
- Trial name
- NCT07815743
- Testing
- Leukocyte-poor platelet-rich plasma, Meniscal Repair
- Where
- Mexico
- Volunteers
- 62 people
- Sponsor
- Universidad Autonoma de Nuevo Leon