Clinical trials: Menopausal
Myocardial Stiffness
The Influence of Menopausal Status on Myocardial Stiffness and Exercise Capacity Among Female Masters Endurance Athletes.
The purpose of this research is to study postmenopausal female masters athletes to see if they will show greater myocardial stiffness and reduced exercise capacity than premenopausal females and similarly aged male masters…
- Trial name
- NCT06475768
- Testing
- Stress Echocardiogram, Cardiovascular Magnetic Imaging (cMRI), Cardiac Magnetic Resonance Elastography (cMRE)
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hot Flashes
A Study to Assess the Safety and Tolerability of Fezolinetant in Women Seeking Treatment for Relief of Vasomotor Symptoms (VMS) Associated With Menopause
This study is for women in menopause with hot flashes. Menopause, a normal part of aging, is the time of a woman's last period. Hot flashes can interrupt a woman's daily life.
- Trial name
- Moonlight 3 (NCT04451226)
- Testing
- Fezolinetant
- Where
- 29 sites in China
- Volunteers
- 150 people
- Sponsor
- Astellas Pharma China, Inc.
Poor Responders
Comparison of Treatment Modalities in Poor Responders Undergoing IVF
The accurate identification and efficient management of poor responders remains one of the most enigmatic challenges in assisted reproductive technology (ART).
- Trial name
- NCT02158689
- Testing
- Letrozole, human menopausal gonadotropin (hMG)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ercan Bastu
Sexual Dysfunctions, Psychological
A One-year Safety Study of Flibanserin to Treat Pre-Menopausal Women With Hypoactive Sexual Desire Disorder (HSDD).
To determine if long-term treatment with Flibanserin is safe and to monitor the effectiveness of Flibanserin in Women with HSDD that have already completed a previous study (511.70/71/.74/.75/.105) with Flibanserin.
- Trial name
- NCT00441558
- Testing
- Flibanserin
- Where
- 196 sites in United States, Canada
- Volunteers
- 1,723 people
- Sponsor
- Sprout Pharmaceuticals, Inc
Breast Cancer Female
Facial Skin Health Tracking Feasibility in Breast Cancer Patients
This feasibility study will assess if tracking objective and subjective facial skin changes over time is acceptable to pre and perimenopausal women undergoing chemotherapy and/or endocrine therapy for breast cancer.
- Trial name
- NCT04035408
- Testing
- Skin health assessment
- Where
- United States
- Sponsor
- University of Colorado, Denver
Breast Cancer
Palbociclib In Combination With Letrozole As Treatment Of Post-Menopausal Women With HR+, HER2- Advanced Breast Cancer
A study of palbociclib in combination with letrozole as treatment of post-menopausal women with hormone receptor-positive, her2-negative advanced breast cancer for whom letrozole therapy is deemed appropriate.
- Trial name
- NCT02679755
- Testing
- Palbociclib, Letrozole
- Where
- 34 sites in Australia, India
- Volunteers
- 252 people
- Sponsor
- Pfizer
Menopause, Obesity, Abdominal
Bioenergetic Effects of Aging and Menopause (BEAM)
The menopause transition is associated with increased risk for weight gain and a shift toward storing fat in the belly region, which may increase risk for cardiovascular disease and diabetes.
- Conditions
- Menopause, Obesity, Abdominal, Aging, Weight Gain
- Trial name
- BEAM (NCT04043520)
- Testing
- GnRH antagonist, Estrogen Product
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obesity, Menopause
Calorie Restriction With Leucine Supplementation
The purpose of this study is to determine whether consuming additional leucine during calorie restriction induced weight loss has beneficial or harmful effects on multi-organ (liver, muscle, adipose tissue) insulin sensitivity…
- Conditions
- Obesity, Menopause, Osteoporosis, Sarcopenia
- Trial name
- NCT01757340
- Testing
- Weight loss with normal protein and leucine intake, Weight loss with protein/leucine supplementation
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Menopause, Premature, Hysterectomy
Perception and Attitude Toward Estrogen Therapy Among Surgically Menopausal Women
The aim of this study is to survey patient's cognition and attitude about health-related quality of life, use of estrogen, experience of menopausal syndrome, compliance of medication, experience, and satisfaction for women who…
- Conditions
- Menopause, Premature, Hysterectomy, Ovariectomy, Estrogen Replacement Therapy
- Trial name
- NCT00173550
- Testing
- Hysterectomy and Bilateral salpingo-oophorectomy
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Infertility, Polycystic Ovary Syndrome
A New Algorithm to Predict Ovarian Age
To collect data of clinical, biochemical and 3D-ultrasonographic parameters of a population of fertile women aged 18-55 in order to design a new algorithm able to predict ovarian age and to evaluate the reliability of a…
- Conditions
- Infertility, Polycystic Ovary Syndrome, Premature Ovarian Failure (POF), Ovarian Cysts
- Trial name
- OvAge (NCT02086318)
- Testing
- OvAge assessment
- Where
- Italy
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Healthy
Estradiol/Norethindrone Acetate Tablets, 1/0.5 mg Under Fasting Conditions
The objective of this study was to determine and compare the rate and extent of absorption of norethindrone and unconjugated estradiol from a test formulation of Estradiol/Norethindrone Acetate Tablets, 1 mg/0.5 mg versus the…
- Trial name
- NCT01157182
- Testing
- Estradiol/Norethindrone acetate, Activella®
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Teva Pharmaceuticals USA
Obesity & Overweight, Women
Effect Of Whole or Skimmed Milk Greek Yogurt on Integrated Muscle Protein Synthesis, Glucose Homeostasis, and Cognition in Post-Menopausal Women
The study will examine the impact of adding two servings per day of skimmed or whole milk Greek yogurt on integrated muscle protein synthesis (iMPS), blood sugar control, and cognition in post-menopausal women with overweight and…
- Conditions
- Obesity & Overweight, Women, Menopause
- Trial name
- NCT07705724
- Testing
- Skimmed vs Whole Milk Greek Yogurt
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Menopause, Hypertension
Non-Comparative Study To Evaluate Changes In FMD After Quinapril Therapy In Hypertensive Women
ACE inhibitors are thought to modify the endothelium in a number of ways. Quinapril is an effective and well-tolerated ACE-I for the treatment of patients with hypertension and congestive heart failure.
- Trial name
- NCT00147524
- Testing
- quinapril, Laser Doppler imaging
- Where
- 5 sites in Hungary
- Volunteers
- 70 people
- Sponsor
- Pfizer
Menopause
The Role of the Gut Microbiota in Estrogen Metabolism and Dietary Flax as a Potential Modulator.
The purpose of this pilot study is to determine if suppressing estrogen in premenopausal women results in changes in gut microbiota and if dietary flaxseed modulates these changes.
- Trial name
- NCT03183102
- Testing
- Flaxseed
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Vaginal Atrophy
DHEA Against Vaginal Atrophy - 3-Month Efficacy Study
The purpose of this Phase III trial is to confirm the efficacy of intravaginal dehydroepiandrosterone (DHEA) in postmenopausal women with vaginal atrophy.
- Trial name
- NCT01256684
- Testing
- DHEA
- Where
- 33 sites in United States, Canada
- Volunteers
- 255 people
- Sponsor
- EndoCeutics Inc.
Dyslipidemia
Berberine, Chlorogenic Acid and Tocotrienols in Menopause-associated Dyslipidemia
Menopause is usually associated with an increase in body weight, a change in body composition and fat distribution and a large number of cardio-metabolic changes, such as hypertension, reduction of insulin-sensitivity and…
- Trial name
- NCT03019263
- Testing
- Nutraceutical, Control
- Where
- Italy
- Volunteers
- 63 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Depressive Disorder, Healthy
The Effect of GnRH on Pitutitary Hormones in Menstrual-Cycle Mood Related Disorders
The normal menstrual cycle is produced by a series of hormonal signals that starts with the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus.
- Conditions
- Depressive Disorder, Healthy, Mental Disorders, Mood Disorders
- Trial name
- NCT00001232
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Menopause, Dyslipidemias
Effect of Polyvitaminics (Pyridoxine Hydrochloride, Folic Acid and Cyanocobalamin) in the Concentration of Homocysteine and Lipid Profile in Postmenopausal Women: a Randomized Controlled, Double-blind Clinical Trial
Introduction: Cardiovascular diseases (CVD) are the main cause of death in Western countries. High levels of homocysteine (He) has been considered an important risk factor for coronary artery disease.
- Conditions
- Menopause, Dyslipidemias, Homocystinaemia
- Trial name
- NCT03221816
- Testing
- Tenavit®
- Volunteers
- 60 people
- Sponsor
- Casa de Saúde santa Marcelina
Post Menopausal Osteoporosis
MOBILE Study - A Study of Bonviva (Ibandronate) Regimens in Women With Post-Menopausal Osteoporosis
This study will compare the efficacy and safety of different treatment regimens of oral Bonviva tablets in women with post-menopausal osteoporosis. Patients will also receive daily supplementation with vitamin D and calcium.
- Trial name
- NCT00048061
- Testing
- Ibandronate [Bonviva/Boniva], Calcium, Vitamin D
- Where
- 68 sites in United States, Australia and 17 more
- Volunteers
- 1,609 people
- Sponsor
- Hoffmann-La Roche
Menopause, Hot Flashes
Acupuncture for Hot Flushes in Menopause
In a pragmatic study investigate whether Traditional Chinese Medicine acupuncture-care decreases the frequency of hot flushes and increases health related quality of life among postmenopausal women.
- Trial name
- ACUFLASH (NCT00284492)
- Testing
- Traditional chinese medicine type acupuncture, Self Care
- Where
- Norway
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.