Clinical trials: Menopausal
Menopause
A Survey Evaluating Prevalence, Severity and Associated Factors in East Asian Women With Moderate-to-severe Menopause-related Vasomotor Symptoms (MR-VMS)
The purpose of this study is to estimate the prevalence of Vasomotor Symptoms (VMS) and prevalence of moderate to severe VMS in peri-menopausal women and post-menopausal women aged 40-65 in East Asia (China, South Korea and…
- Trial name
- NCT04553029
- Testing
- No intervention
- Where
- 3 sites in China, South Korea and 1 more
- Volunteers
- 3,399 people
- Sponsor
- Astellas Pharma Singapore Pte. Ltd.
Menopause Syndrome
Evaluation of the Efficacy and Safety of A High Molecular Weight, Natural Hyaluronic Acid Vaginal Gel in Women With Genitourinary Syndrome of Menopause
The aim of the study is to evaluate the safety and efficacy of the vaginal gel with HMW HA in women with genitourinary syndromes due to either menopause or other causes such as the patients after ovarian or breast cancer…
- Trial name
- NCT05263102
- Testing
- Vaginal Moisturizing Gel
- Where
- 4 sites in Taiwan
- Volunteers
- 80 people
- Sponsor
- HAN Biomedical Inc
Postmenopausal Symptoms
A Study of the Safety and Effect of Repeated Administration of G-CSF on Hot Flashes in Postmenopausal Women
The purpose of this study is to assess the efficacy and safety of repeated administration of G-CSF for the treatment of hot flashes and vasomotor symptoms in women with naturally-occurring or surgically induced menopause.
- Trial name
- NCT03640754
- Testing
- G-CSF
- Where
- 2 sites in United States
- Volunteers
- 61 people
- Sponsor
- MenoGeniX, Inc.
Menopausal Women, Menopausal Symptom Relief
Comparison of Oral Dydrogesterone and Vaginal Progesterone in Menopausal Hormone Therapy
Menopause is a natural stage in a woman's life that can be associated with symptoms such as hot flashes, night sweats, sleep problems, and vaginal dryness. Menopausal hormone therapy is commonly used to relieve these symptoms.
- Conditions
- Menopausal Women, Menopausal Symptom Relief, Hormone Therapy, Menopausal Hormone Therapy
- Trial name
- PRO-MHT (NCT07496294)
- Testing
- Dydrogesterone 10 MG Oral Tablet, Micronized progesterone 200 MG, Transdermal estradiol
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Menopause, Hot Flashes
Black Cohosh Extract in Postmenopausal Breast Health
The purpose of the study is to determine if black cohosh extract (BCE) administration in symptomatic postmenopausal women results in estrogenic stimulation of the breast, as determined by estradiol, pS2, FSH, LH, and PSA levels…
- Trial name
- NCT00064831
- Testing
- Black Cohosh Extract (BCE)
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Postmenopausal Symptoms, Telerehabilitation
Relaxation Training Via Tele-Rehabilitation in Postmenopausal Women
Menopause is associated with various physiological and psychological changes that may adversely affect women's quality of life. Menopausal symptoms, sleep disturbances, and fatigue are among the most common complaints during the…
- Conditions
- Postmenopausal Symptoms, Telerehabilitation, Relaxation Training, Menopause
- Trial name
- NCT07737691
- Testing
- Relaxation Training Delivered via Tele-Rehabilitation
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marmara University
Unilateral Post-mastectomy, Post-menopausal
Lung Boost Therapy on Post-mastectomy Postmenopausal
The goal of this randomized controlled trial is to compare the influences of a traditional pulmonary rehabilitation program versus a combined program including the Lung Boost device on pulmonary function and quality of life in…
- Trial name
- NCT07608042
- Testing
- Breathing Exercises, Lung Boost device in addition to Behavioral: Breathing exercises
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ahram Canadian University
Hot Flushes, Menopause, Postmenopause
Comparison of Estrogen and Methyltestosterone Combination Treatments for Postmenopausal Hot Flushes
This is a research study to evaluate the effectiveness, safety and side effects of several dose levels of esterified estrogens (EE) and methyltestosterone (MT) given individually and in combination compared to a placebo (a tablet…
- Trial name
- NCT00160342
- Testing
- Esterified Estrogens (EE) and Methyltestosterone (MT)
- Where
- 125 sites in United States, Canada and 1 more
- Volunteers
- 1,251 people
- Sponsor
- Solvay Pharmaceuticals
Infertility (IVF Patients)
Human Menopausal Gonadotropin Research in Infertility Assessing Cumulative Live Birth With Frozen Embryo Transfer.
The goal of this multicenter, randomized, placebo-controlled, double-blind clinical trial is toto evaluate the efficacy and safety of a human menopausal gonadotropin (hMG) in the development of multiple follicles, pregnancy, and…
- Trial name
- GRACE (NCT07216742)
- Testing
- hMG subcutaneous injection
- Where
- 16 sites in United States
- Volunteers
- 659 people
- Sponsor
- Granata Bio Corporation
Mindfulness Compassionate Living Training
Menopause and Compassionate Living Education
Menopause is a natural stage in a woman's life characterized by the permanent cessation of ovarian function and is frequently accompanied by vasomotor, psychological, urogenital, and sleep-related symptoms that can substantially…
- Trial name
- NCT07728461
- Testing
- Session 1: How We Evolved - Threat, Impulse, and Soothing Systems, Session 2: Threat and Self-Compassion, Session 3: Unraveling the Knots of Desire and Patterns
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ataturk University
Advanced Breast Cancer
Study Evaluating Bosutinib-Exemestane Combination Vs Exemestane Alone in Post Menopausal Women With Breast Cancer
This is a phase 2, open-label, multicenter, 2-arm study of bosutinib administered in combination with exemestane versus exemestane alone. This is a 2-part study consisting of a safety lead-in phase and randomized phase 2 portion.
- Trial name
- NCT00793546
- Testing
- Bosutinib, exemestane
- Where
- 28 sites in United States, Australia and 9 more
- Volunteers
- 42 people
- Sponsor
- Pfizer
Endometriosis
A Study to Investigate Efficacy and Safety of OG-6219 BID in 3 Dose Levels Compared With Placebo in Participants Aged 18 to 49 With Moderate to Severe Endometriosis-related Pain
The purpose of this global Phase 2 study is to determine the efficacy, safety, and tolerability of 3 dose levels of OG-6219 in pre-menopausal women between 18 and 49 years of age (inclusive), who have moderate to severe…
- Trial name
- ELENA (NCT05560646)
- Testing
- OG-6219
- Where
- 86 sites in United States, Belgium and 9 more
- Volunteers
- 354 people
- Sponsor
- Organon and Co
Osteopenia, Generalized
Evaluate the Effect of Lifenol in Improving Bone Status in Postmenopausal Osteopenic Women
A Randomised, Double-blind, Placebo-controlled Clinical Trial to Evaluate the Effect of Lifenol® in Improving Bone Status in Postmenopausal Osteopenic Women.
- Trial name
- NCT04004013
- Testing
- Lifenol®
- Where
- Ireland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Givaudan France Naturals
Menopause
Safety Study of Black Cohosh Use by Postmenopausal Women on the Liver
Black Cohosh extract is a form of phytoestrogen (estrogen of plant origin) that is effective in controlling bothersome hot flushes, while avoiding the dangers of using hormones.
- Trial name
- CR-LIVER (NCT00794690)
- Testing
- Cimicifuga racemosa extract for the group
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Obesity
Acupuncture for Obesity on Serum Metabolic Parameters
This research is planned to build a basis about the effect of acupuncture on serum metabolic parameters in pre-menopausal obese women with economic evaluation.
- Trial name
- NCT02066090
- Testing
- Real acupuncture
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
Moderate Depression, Menopausal and Postmenopausal Disorders
Homeopathic Treatment for Depression in Peri- and Postmenopausal Women
The aim of this study was to determine whether individualized homeopathic treatment and fluoxetine are more efficient than placebo for moderate to severe depression in peri- and postmenopausal women.
- Trial name
- HOMDEP-MENOP (NCT01635218)
- Testing
- Individualized homeopathic treatment, Fluoxetine
- Where
- Mexico
- Volunteers
- 133 people
- Sponsor
- Hospital Juarez de Mexico
Vulvovaginal Atrophy, Genital Disorder
Psychometric Validation of the Portuguese DIVAS-Q in Women With Vulvovaginal Atrophic Symptoms
To determine the reliability and validity of the Portuguese version of the DIVA questionnaire in Portuguese women. This validation will support its use both in research and in routine clinical practice in this population.
- Conditions
- Vulvovaginal Atrophy, Genital Disorder, PROMs
- Trial name
- DIVAS-Q (NCT07250490)
- Where
- Portugal
- Volunteers
- 300 people
- Sponsor
- Instituto Politécnico de Leiria
Gynecological Malignancies, Menopausal Symptoms
An Observational Study of Menopausal Symptom in Patients With Gynecological Malignancy After Oophorectomy
Through long-term dynamic monitoring of gynecologic malignant tumor patients undergoing early menopause after ovaries resection in our center, we explored the changes in menopausal symptoms and bone health status of this…
- Conditions
- Gynecological Malignancies, Menopausal Symptoms, Bone Loss
- Trial name
- NCT06151028
- Testing
- No intervention
- Where
- China
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- Anhui Provincial Hospital
Menopause Related Conditions
Menopause Racing Heart Study
Palpitations occur in more than 25% of women as they approach menopause and after menopause. However, the etiology of menopausal palpitations has not been studied, and it is unknown whether palpitations in menopausal women are…
- Trial name
- NCT05062057
- Testing
- Adhesive ambulatory ECG recording patches
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Indiana University
Healthy
Muscle Mass, Quality, and the Menopause: Sex-specific Strategies to Mitigate Sarcopenia in Ageing Populations
Aging causes muscles to often become smaller and weaker resulting in physical frailty and functional impairments, such as difficulty raising from a chair, dressing, and preparing meals.
- Trial name
- NCT06806501
- Testing
- Unilateral Resistance Exercise
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
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