Clinical trials: Menopause Syndrome
Vaginal Atrophy, Genitourinary Syndrome of Menopause
The Efficacy of Topical Vaginal Oxytocin Gel in Postmenopausal Women With Vulvovaginal Atrophy
A Phase three randomized, double-blinded, study to asses the efficacy and safety of oxytocin gel in postmenopausal women with vaginal atrophy due to Genitourinary Syndrome of Menopause GSM.
- Conditions
- Vaginal Atrophy, Genitourinary Syndrome of Menopause, Vulvar Atrophy
- Trial name
- NCT06514586
- Testing
- Oxytocin, Hydroxypropyl methylcellulose
- Where
- Egypt
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Oxagon
Menopausal Syndrome, Sexual Dysfunctions
Investigation of the Effects of Pilates Exercises on Menopause Symptoms and Sexual Dysfunction in Postmenopausal Women
Menopause represents a major transition in a woman's life as estrogen and progesterone levels decline, and this hormonal shift is associated with a range of symptoms that can significantly impact a woman's quality of life…
- Conditions
- Menopausal Syndrome, Sexual Dysfunctions, Quality of Life and Menopause
- Trial name
- NCT06837714
- Testing
- PİLATES GROUP, Behavioral: lifestyle changes
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Batman University
Menopause, Vasomotor; Syndrome
Efficacy of Nano-Pso Therapy in Menopause
Vasomotor syndrome is prevalent in 85% of postmenopausal women, hormone therapy in menopause is first-line therapy, but 38% of patients have some contraindication for its use.
- Trial name
- NCT06432816
- Testing
- NANO-PSO
- Where
- Mexico
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Distribuidora Biolife SA de CV
Menopause, Metabolic Syndrome
Low Sexual Desire and Metabolic Syndrome
Objective: To evaluate the prevalence of hypoactive sexual desire disorder (HSDD) in postmenopausal women diagnosed with metabolic syndrome (MS) and to compare it to that of a control group without MS.
- Conditions
- Menopause, Metabolic Syndrome, Hypoactive Sexual Desire Disorder, Obesity
- Trial name
- NCT02430987
- Testing
- Female sexual function index questionnaire, Evaluation of presence of metabolic syndrome, Evaluation of the body mass index
- Where
- Brazil
- Volunteers
- 291 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Menopausal Complaints, Vaginal Atrophy
Vaginal Estradiol vs Moisturizer to Improve Postmenopausal Vaginal Aging Symptoms and the Microbiome in Women Living With HIV
This is a research study about the effects of vaginal estradiol compared to moisturizer on vaginal symptoms of menopause and the microbiome in women with HIV.
- Conditions
- Menopausal Complaints, Vaginal Atrophy, Genitourinary Symptoms, HIV (Human Immunodeficiency Virus)
- Trial name
- NCT07526948
- Testing
- Vaginal estradiol tablets, Vaginal moisturizer
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Genitourinary Syndrome of Menopause (GSM), Vaginal Dryness
To Assess Signs and Symptoms in Women Affected by GSM After One Cycle of Pixel CO2-Alma Fractionated Laser
Genitourinary syndrome of menopause (GSM) occurs in approximately 50% of menopausal women but is both underrecognized and undertreated despite numerous treatment options.
- Conditions
- Genitourinary Syndrome of Menopause (GSM), Vaginal Dryness, Burning, Pain
- Trial name
- NCT05156502
- Testing
- Fractionated Laser (Pixel CO2-Alma), Fractionated Laser (Pixel CO.2-Alma)
- Where
- Italy
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dr. Filippo Murina
Metabolic Syndrome
Early Vascular Wall Changes by Magnetic Resonance Imaging (MRI) in Metabolic Syndrome Versus Metabolically Normal Pre-Menopausal Women: A Pilot Study
The purpose of this study is to compare the vascular permeability of blood vessel walls (of the carotid artery) in pre-menopausal women who have metabolic syndrome (syndrome of having at least 3/5 following features- increased…
- Trial name
- NCT01068535
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Washington
Genitourinary Syndrome of Menopause
MonaLisa Touch Randomized Double-Blind Placebo Controlled Study
Aim of the study: To assess the efficacy of MonaLisa Touch procedure for the management of genitourinary syndrome of menopause (GSM) in a randomized double-blind placebo controlled study.
- Trial name
- NCT03331328
- Testing
- MonaLisa Touch
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Michigan Institution of Women's Health PC
Human Immunodeficiency Virus
Safety and Pharmacokinetics of Dapivirine Vaginal Ring in Post-menopausal Women
This study will evaluate the safety of the dapivirine vaginal ring when inserts once every 4 weeks in postmenopausal women over 12 weeks of product use.
- Trial name
- NCT02010593
- Testing
- Dapivirine Vaginal Ring
- Where
- 3 sites in United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- International Partnership for Microbicides, Inc.
Celiac Disease, Diet, Gluten-Free
Improvement Of Physical And Physiological Parameters In Menopausal Or Post-Menopausal Celiac Women
Celiac disease (CD) is an immunological disorder that mainly affects the small intestine, generating an inflammatory process in response to the presence of gluten (a protein).
- Conditions
- Celiac Disease, Diet, Gluten-Free, Exercise, Resistance Training
- Trial name
- NCT05052164
- Testing
- Gluten-free nutrition plan + exercise group, Gluten-free nutrition plan group, Active Comparator: Celiac controls group
- Where
- Spain
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Alicante
Atrophic Vaginitis, Menopause
Vaginal and Urinary Microbiome Trial
A randomized controlled trial looking at the effects of vaginal estrogen and a nonhormonal alternative on the vaginal and urinary microbiome in women with genitourinary syndrome of menopause.
- Conditions
- Atrophic Vaginitis, Menopause, Recurrent Urinary Tract Infections
- Trial name
- NCT02869165
- Testing
- Conjugated equine estrogen topical cream, Apricot kernel oil
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Infertility, Polycystic Ovary Syndrome
A New Algorithm to Predict Ovarian Age
To collect data of clinical, biochemical and 3D-ultrasonographic parameters of a population of fertile women aged 18-55 in order to design a new algorithm able to predict ovarian age and to evaluate the reliability of a…
- Conditions
- Infertility, Polycystic Ovary Syndrome, Premature Ovarian Failure (POF), Ovarian Cysts
- Trial name
- OvAge (NCT02086318)
- Testing
- OvAge assessment
- Where
- Italy
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University Magna Graecia
Postmenopausal Metabolic Health
Physical Activity and Basal Metabolic Rate in Postmenopausal Women
The primary purpose of this study is to expand research on the effects of physical activity on basal metabolic rate (BMR) in healthy postmenopausal women, and to further compare the effects of long-term habitual exercise to the…
- Trial name
- NCT01550536
- Testing
- Resistance and aerobic exercise
- Where
- 3 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Female Infertility Due to Diminished Ovarian Reserve, Menopausal Syndrome
Cohort Study to Evaluate Ovarian Function
The study will collect the clinical and biological data of the patients, the investigators could further analyse and identify the risk factors and optimize clinical treatment method.
- Conditions
- Female Infertility Due to Diminished Ovarian Reserve, Menopausal Syndrome, Sexual Function and Fertility Disorders, Cardiovascular Diseases
- Trial name
- NCT02294500
- Where
- China
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Shixuan Wang
Metabolic Syndrome, Postmenopausal Disorder
Inofolic NRT and the Metabolic Syndrome
A prospective, randomized, controlled, open-label study will be carried out on 80 post-menopausal women affected by the metabolic syndrome (criteria are described in NIH ATP III).
- Trial name
- NCT01400724
- Testing
- Inofolic NRT
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Messina
Vaginal Atrophy
Vaginal CO2 Laser and the Genitourinary Syndrome of Menopause
This study evaluates the clinical, histopathological, cytological and microbiological efficacy of Microablative Fractional CO2 laser intravaginally administered in postmenopausal women with Genitourinary Syndrome of Menopause.
- Trial name
- NCT03754205
- Testing
- Microablative Fractional CO2 laser
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Vasomotor; Syndrome, Sleep
The Effect of Laughter Yoga on Vasomotor Symptoms and Sleep Quality
The research was planned as a prospective, randomized controlled experimental study to determine the effect of online laughter yoga applied to menopausal women on vasomotor symptoms (VMS) and sleep quality.
- Trial name
- NCT05859594
- Testing
- Laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mersin University
HIV Infections, Menopause
Metabolic and Psychological Changes Associated With Menopause Among Women With HIV
This study will investigate the prevalence and extent of both metabolic and psychosocial changes associated with the menopause transition over 1 year among women with HIV compared to women without HIV of similar age, weight…
- Trial name
- NCT01142817
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Quality of Life, Menopausal Syndrome
Efficacy and Safety of Oral DHEA Therapy for Postmenopausal Women on Sexual Function, Wellbeing and Vasomotor Symptoms
This study is designed to evaluate the efficacy and safety of oral Dehydroepiandrosterone (DHEA) 50mg daily, for 12 months in naturally menopausal women with low libido who are not receiving systemic oestrogen or oestrogen…
- Conditions
- Quality of Life, Menopausal Syndrome, Libido Disorder
- Trial name
- NCT00289926
- Testing
- dehydroepiandrosterone
- Where
- Australia
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Monash University
Climacteric Syndrome, Menopause
Clinical Evaluation of Effectiveness and Safety of Amberen and Smart B by Women With Climacteric Syndrome
To evaluate effectiveness and safety of combined use of dietary supplements Amberen and Smart B by women with a typical (without complications) form of climacteric syndrome, with mild to moderate symptoms.
- Trial name
- NCT03118908
- Testing
- Amberen, Smart B
- Where
- Russia
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University