Clinical trials: Menstrual Cycles
Hyponatraemia, Hypernatraemia
Do Changes in Plasma Osmolality Influence Ventilation?
Primary hypothesis: osmolality changes influence the sensitivity of the respiratory center to carbon dioxide, hyponatraemia causing hyperventilation, and hypernatraemia depressing ventilation.
- Trial name
- OSM (NCT01008644)
- Testing
- Water, Saline 3%
- Where
- Sweden
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Vibeke Moen
Menstrual Cycle, Exercise Performance Impairment
Eccentric Exercise, Muscle Damage, and Oxygen Uptake Across Menstrual Cycle Phases
The existing literature examining the effect of female sex hormones across the phases of the menstrual cycle on muscle microdamage and oxygen uptake is limited.
- Trial name
- EEMDO-MC (NCT07581067)
- Testing
- Isokinetic eccentric exercise using knee extensors of the right lower limb, Isokinetic eccentric exercise using knee extensors of the left lower limb
- Where
- Greece
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Dysmenorrhea, Dysmenorrhea Primary
A Research Study Exploring How Musculoskeletal Function and the Autonomic Nervous System Relate to Visceral Pain in Women With and Without Dysmenorrhea (Painful Periods).
The purpose of this clinical trial is to determine if women with dysmenorrhea demonstrate an increased musculoskeletal and autonomic nervous system response to a painful visceral stimulus compared to controls.
- Conditions
- Dysmenorrhea, Dysmenorrhea Primary, Visceral Pain, Menstrual Pain
- Trial name
- NCT07209566
- Testing
- Visceral Pain Stimulus
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Azusa Pacific University
Sexual Dysfunction, Physiological
Effect Of Menstrual Cycle On Vaginal Blood Flow In Pre-Menopausal Healthy Women.
The Pfizer developed Heat Wash-Out (HWO) system is a software controlled electromechanical system designed to measure vaginal wall blood flow. A small vaginal probe is attached to a control unit. Output data is collected on a PC.
- Trial name
- HWO VBF (NCT00443027)
- Testing
- Vaginal Heat Wash-Out Device
- Where
- 2 sites in Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Ovulation; Failure or Lack of
Hormonal Effects of the Oral Gonadotropin Releasing Hormone (GnRH) Antagonist at Different Periods of the Menstrual Cycle
The purpose of this study is twofold: First, to see if elagolix can suppress gonadotropin and ovarian hormones in the short-term period, when only administered for a 72-hour period.
- Trial name
- NCT04060992
- Testing
- Elagolix 200 MG Oral Tablet [Orilissa]
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Normal Body Weight, Obesity
Endocrine and Neural Control of Eating in Women
The purpose of this study is to better understand how female sex hormones influence the food intake in the gut system through the release of satiety hormones as well as through central regulative mechanisms in the brain that…
- Trial name
- NCT02994420
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Menstrual Cycle
The Effect of Menstruation on Food Preference and Balance
Menstruation period, which is accepted as the symbol of fertility, and some problems related to this process covers half of a woman's life.
- Trial name
- NCT05821439
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Cortical Activation
Menstrual Cycle TMS Plasticity Pilot
Aim 1: Assess how menstrual cycle phase affects motor cortex plasticity in females. Aim 2: Compare motor cortex plasticity between males and females across the same time points, identifying potential sex differences in TMS…
- Trial name
- NCT07180654
- Testing
- transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Menstrual Cycle
Menstrual Phase and Smoking Cessation at a State Quitline
Quitlines are efficient and cost-effective treatments for smoking cessation, yet little research has explored how to personalize and optimize quitline services for women.
- Trial name
- Project Phase (NCT03908320)
- Testing
- Menstrual Cycle Timing, NRT Patch, Cessation Counseling
- Where
- United States
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Aging
Age-related Changes in Ovarian Follicular Wave Dynamics
The investigators hypothesize that age-related changes in the number and growth dynamics of ovarian follicles will be associated with changes in hormone levels and corresponding changes in musculoskeletal health.
- Trial name
- NCT01389141
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Menstrual Cycle, Oral Contraceptive Use
Characterization of the Mechanical Properties of the Hamstring Muscle Group in Female.
The goal of this clinical trial is to precise the impact of menstrual cycle and physical activity on the hamstrings muscle function in healthy active women.
- Trial name
- MECA_CYCLE (NCT05802277)
- Testing
- Hamstring muscles function assessment
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- EZUS-LYON 1
Irritable Bowel Syndrome
Effect of Menstrual Cycle on Central Nervous System (CNS) Processing of Gut Stimuli in Irritable Bowel Syndrome (IBS) and Control
The hypothesis of the study is that women perceive intestinal stimulation (rectal balloon distention) differently in different phases of the menstrual cycle, i.e there is an effect of hormones on the sensory pathway, and that…
- Trial name
- NCT00219531
- Testing
- perception of rectal balloon distention
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Penn State University
Infertility, Female, Perimenopausal Disorder
Autologous Platelet Rich Plasma (PRP) Intra Ovarian Infusion in Perimenopausal Women
Autologous PRP intra ovarian infusion may improve ovarian response and women's hormonal profile and may promote folliculogenesis in perimenopausal women.
- Conditions
- Infertility, Female, Perimenopausal Disorder, Menstrual Cycle Abnormal
- Trial name
- PRP (NCT03951194)
- Testing
- Autologous Platelet Rich Plasma (PRP) intra ovarian infusion
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Genesis Athens Clinic
Creative Drama, Genital Hygiene
Creative Touch in Menstrual Attitude and Hygiene Behavior: A Drama Intervention
In this study, the effect of creative drama-based education on menstruation attitudes and genital hygiene behaviors of adolescent girls aged 10-14 years was investigated.
- Conditions
- Creative Drama, Genital Hygiene, Menstrual Cycle, Adolescent
- Trial name
- NCT07026396
- Testing
- Creative drama group
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Depressive Disorder, Healthy
The Effect of GnRH on Pitutitary Hormones in Menstrual-Cycle Mood Related Disorders
The normal menstrual cycle is produced by a series of hormonal signals that starts with the release of gonadotropin-releasing hormone (GnRH) from the hypothalamus.
- Conditions
- Depressive Disorder, Healthy, Mental Disorders, Mood Disorders
- Trial name
- NCT00001232
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Embryo Transfer, Irregular Menstruation
Letrozole-stimulated Cycle Strategy Versus Artificial Cycle Strategy (LETSACT)
The goal of this randomized clinical trial is to evaluate the effectiveness of the letrozole-stimulated cycle strategy versus the artificial cycle strategy for endometrial preparation in women with irregular menstrual cycles…
- Conditions
- Embryo Transfer, Irregular Menstruation, Letrozole, Hormone Replacement Therapy
- Trial name
- NCT06372119
- Testing
- Letrozole-stimulated cycle strategy, Artificial cycle strategy
- Where
- 2 sites in Vietnam
- Volunteers
- 790 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
Menstrual Cycles
Period Tracker at Home Study
This study will assess the usability of a Period Tracker product when used by lay users in their own homes.
- Trial name
- NCT05088382
- Testing
- LH Urine Test
- Where
- United Kingdom
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- SPD Development Company Limited
Neural Activity, Brain Function
Whole-Brain Dynamics in the Natural Menstrual Cycle vs. an Ovarian Stimulated Cycle: Impact of Hormonal Fluctuations on Healthy Women Undergoing Ovarian Stimulation
The investigators aim is to investigate the brain's dynamic complexity across three phases of an ovarian stimulation cycle (basal, pre-OPU, mid-luteal), to observe the impact of externally administered hormones, and compare it…
- Conditions
- Neural Activity, Brain Function, Neurodynamics, Brain Connectivity
- Trial name
- NCT06910293
- Testing
- Functional Magnetic resonance imaging will be done on day 2 or 3 of the menstrual cycle, trigger-shot and egg retrieval.
- Where
- 2 sites in United Arab Emirates
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Sleep Deprivation, Menstrual Cycle
The Effects of Night Shift Work on Health Across the Menstrual Cycle
The study aims to investigate the effects of sleep deprivation on women's health across different phases of the menstrual cycle.
- Conditions
- Sleep Deprivation, Menstrual Cycle, Brain Health, Metabolism
- Trial name
- MENSLEEP (NCT06683248)
- Testing
- Investigate sleep deprivation
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uppsala University
PMS, Menstrual Discomfort
An Investigation of Premama Balance and Its Effects on Hormonal Imbalances
An investigation of the dietary supplement marketed as "Premama Balance" on markers of subjective wellbeing in trial participants such as common symptoms of PMS and menstrual symptoms, as well as its effects on aiding in…
- Conditions
- PMS, Menstrual Discomfort, Hormone Disturbance, Menstrual Pain
- Trial name
- NCT05518006
- Testing
- PreMama Balance
- Volunteers
- healthy volunteers welcome
- Sponsor
- Premama Inc.