Clinical trials: Mental Illness
HIV Infections, Sleep Disorder
Assessment of Sleep Disordersin People Living With HIV in the Era of New Antiretroviral Therapies in North of France
People living with HIV (PLHIV) appear to present with sleep-related complaints more frequently than the general population, with a prevalence of 50-70%. The latest French multi-center epidemiological data are dated.
- Trial name
- SANDMAN (NCT06441383)
- Testing
- Pittsburgh Sleep Quality Index
- Where
- France
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Tourcoing Hospital
Depression, Anxiety
BEhavioral Health Stratified Treatment (BEST) Study for Youth With Intellectual and/or Developmental Disabilities (IDD)
Many youth with disabilities and their families receive "care coordination services" from a state Maternal and Child Health Bureau (MCHB) agency.
- Conditions
- Depression, Anxiety, Transition
- Trial name
- BEST (NCT05520983)
- Testing
- Adapted Teens Achieving Mastery over Stress (TEAMS) Treatment, Adapted Teens Achieving Mastery over Stress (TEAMS) Prevention, Adapted Competent Adulthood Transition with Cognitive-behavioral & Interpersonal Training (CATCH-IT)
- Where
- United States
- Volunteers
- 780 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Cognitive Decline, Executive Dysfunction
Fitness on White Matter and Cognition in Aging
Cardiorespiratory fitness (CRF) is associated with decreased risk for mild cognitive impairment (MCI) and dementia. CRF is linked with more conserved gray and white matter (WM) volume, improved WM microstructural integrity, and…
- Conditions
- Cognitive Decline, Executive Dysfunction, Cardiovascular Risk Factor
- Trial name
- NCT03775941
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- Suffolk University
Alcohol Dependence
Safety and Efficacy of Nalmefene in Patients With Alcohol Dependence
The purpose of the study is long-term safety, tolerability and efficacy of nalmefene in patients with alcohol dependence.
- Trial name
- SENSE (NCT00811941)
- Testing
- Nalmefene
- Where
- 60 sites in Czechia, Estonia and 8 more
- Volunteers
- 665 people
- Sponsor
- H. Lundbeck A/S
Insomnia Disorder
Optimizing an Integrated Mind and Body Treatment for Insomnia: The SLEEPS Study 2
This two-arm randomized trial will provide digital cognitive behavioral therapy for insomnia (CBT-I) to all participants and passive body heating (PBH) sessions using a sauna blanket to half of participants over a 9-week…
- Trial name
- SLEEPS2 (NCT07036705)
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I), Passive Body Heating (PBH)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Mild Cognitive Impairment
Dual-task Training for Function in MCI
Mild cognitive impairment (MCI) is an intermediate stage between the expected cognitive decline of normal aging and severe dementia associated with Alzheimer's disease (AD).
- Trial name
- NCT04059705
- Testing
- Dual-Task Training
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- State University of New York at Buffalo
Pain Management
Effect of Chewing Different Flavor Gum on Procedural Pain and Fear
Needle-related pain and anxiety present persistent challenges in pediatric clinical procedures. This study aims to investigate the effects of chewing sugared and sugar-free gum on pain, anxiety, and fear in children undergoing…
- Trial name
- Gum-Pain (NCT07326254)
- Testing
- Sugared Gum Chewing, Sugar-Free Gum Chewing, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Gastrointestinal Problems, Autism Spectrum Disorders
Beneficial Bacteria Treatment for Autism
This is an open-label clinical trial to investigate a combination therapy for treating gastrointestinal problems in children with autism spectrum disorders. The combination therapy includes beneficial bacteria.
- Trial name
- BBT (NCT02504554)
- Testing
- oral Vancomycin, MoviPrep, Prilosec
- Volunteers
- 18 people
- Sponsor
- Arizona State University
Bipolar Disorder
Time-Restricted Eating and Bipolar Disorder
This is a pilot trial to examine the acceptability and feasibility of time-restricted eating as an adjunct to medication treatment for bipolar disorder.
- Trial name
- NCT06105294
- Testing
- time-restricted eating
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of California, Berkeley
Occupational Therapy
AI-Supported Occupational Therapy for Handwriting
Aim: This study investigates the impact of an AI-supported occupational therapy program, developed using the Model of Human Occupation (MOHO), on handwriting skills in children at risk for Developmental Coordination Disorder…
- Trial name
- NCT06871566
- Testing
- Artificial Intelligence-Supported Occupational Therapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Hacettepe University
Depression, Anxiety
Shaping Neural Activity Through Parenting
The purpose of this study is to test causal links between dimensions of positive and harsh parenting and children's brain responses to rewards and errors, using a parenting intervention.
- Trial name
- SNAP (NCT02667522)
- Testing
- Parent Child Interaction Therapy (PCIT)
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Sleep Disorder
Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study of ABT-652 in Subjects With Excessive Daytime Sleepiness
The main purpose of this study is to evaluate the safety and tolerability of the drug ABT-652 given once daily to people with excessive daytime sleepiness.
- Trial name
- NCT01124851
- Testing
- ABT-652
- Where
- 5 sites in United States
- Volunteers
- 36 people
- Sponsor
- Abbott
Prematurity, Parenting
Study of the Quality of Sleep of Parents of Premature Children Compared to Parents of Full-term Children
This study evaluate the incidence of sleep disorders in parents of premature children hospitalized in unit care of neonatalogy or intensive unit care of neonatalogy, compared to parents of full-term child in maternity.
- Conditions
- Prematurity, Parenting, Sleep Deprivation
- Trial name
- SLEEP-PP (NCT03693651)
- Where
- France
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Mental Health Wellness 1, Depression, Anxiety
Mental Health in Fitness Instructors
The aim of this project is to improve the evidence-base regarding lifestyle and mental health symptoms among fitness instructors.
- Conditions
- Mental Health Wellness 1, Depression, Anxiety, Eating Disorders, Eating Behavior
- Trial name
- NCT04135729
- Where
- Norway
- Volunteers
- 304 people
- Sponsor
- Norwegian School of Sport Sciences
Postoperative Cognitive Complications
Spinal Anesthesia Vs. Neve Block in Risk of Cognitive Decline
Hip fracture is a potentially devastating event, and serious surgical and medical complications occur frequently especially for elderly patients. Delirium is one of the common complications after hip surgery.
- Trial name
- NCT06963229
- Testing
- Spinal Anesthesia (bupivacaine), Peripheral Nerve Block
- Where
- Lebanon
- Volunteers
- 50 people
- Sponsor
- Makassed General Hospital
Schizophrenia
High Dose D-Serine as Adjuvant Treatment for Recent Onset Schizophrenia
The purpose of this study is to compare efficacy and safety of add-on treatment with a moderately high dose of D-serine, an NMDA-glycine site agonist, in young, recent onset schizophrenia patients who suffer from significant…
- Trial name
- SATROS (NCT01459029)
- Testing
- D-serine
- Where
- 2 sites in Israel
- Volunteers
- 54 people
- Sponsor
- Hadassah Medical Organization
Obsessive-Compulsive Disorder
Double Blinded, Placebo-Controlled Trial of Paliperidone Addition in SRI-Resistant Obsessive-Compulsive Disorder
Obsessive-compulsive disorder (OCD) is a common, chronic, and oftentimes disabling disorder. The only established treatments for OCD are a specific form of Cognitive Behavioral Therapy (CBT) and the Serotonin Reuptake Inhibitor…
- Trial name
- NCT00632229
- Testing
- Paliperidone
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- University of South Florida
Treatment Resistant Disorders, Post Traumatic Stress Disorder
Investigating the Therapeutic Effects of Psilocybin in Treatment-Resistant Post-Traumatic Stress Disorder
Post-traumatic stress disorder (PTSD) is a complex disorder expressed as a variety of neurobiological symptoms, including anxiety, re-experiencing, hyperarousal, and avoidance symptoms, along with comorbidities such as anxiety…
- Trial name
- NCT05243329
- Testing
- Psilocybin
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Halucenex Life Sciences Inc.
Pain, Anxiety
Humor Therapy and Rheumatoid Arthritis
The goal of this prospective, randomized controlled study was to inverstigate the effect of humor on pain and in patients with rheumatoid arthritis (RA) during IV treatment.
- Conditions
- Pain, Anxiety, Rheumatoid Arthritis, Nursing Caries
- Trial name
- NCT05877937
- Testing
- Supportive care (Watching a comedy movie)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Eskisehir Osmangazi University
Dementia
Factors Influencing the Deterioration From Cognitive Decline of Normal Aging to Dementia Among Nursing Home Residents
Background: A dearth of differential research exists regarding the determinants of mild cognitive impairment (MCI) and moderate cognitive impairment or dementia among nursing home residents.
- Trial name
- NCT04589637
- Where
- Jordan
- Volunteers
- 182 people
- Sponsor
- Jordan University of Science and Technology
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