Clinical trials: Mental Stress
PTSD
Effects of Escitalopram on Autonomic Reactivity in Post Traumatic Stress Disorder
The study looked at relationship between escitalopram and heart rate variability and QT variability in veterans with PTSD.
- Trial name
- NCT01271244
- Testing
- Escitalopram
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- VA Nebraska Western Iowa Health Care System
Atrial Septal Defect (ASD), Dexmedetomidine
Effect of Dexmedetomidine Supplementation to General Anaesthesia in Paediatric Transcatheter Closure of Atrial Septal Defect
The aim of this randomized trial is to determine efficacy of dexmedetomidine in improving quality of recovery in pediatric patients undergoing interventional catheter closure of ASD while maintaining the hemodynamic parameters.
- Conditions
- Atrial Septal Defect (ASD), Dexmedetomidine, Delirium - Postoperative, Stress Response
- Trial name
- NCT06631534
- Testing
- Dexmedetomidine
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Autism Spectrum Disorder
Sensory and Behavioral Aspects With Particular Attention to Food Selectivity in Children With Autism
Brief Summary: Eating problems and in particular food selectivity is a condition that worsens a long-life disorder such as Autism Spectrum Disorder (ASD) , both on an individual level, both on family and social ones .
- Trial name
- NCT06335030
- Where
- 3 sites in Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Fondazione Stella Maris
In Vitro Fertilization, Psychological Stress
Does Emotional Support Decrease In Vitro Fertilization Stress?
In vitro fertilization for infertility has been associated with a significant amount of treatment related stress for patients. In addition,stress levels increase between embryo transfer and pregnancy test, during this waiting…
- Trial name
- NCT01406028
- Testing
- Phone calls
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- Brigham and Women's Hospital
Delirium, Cognitive Impairment
Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy
The purpose of this study is to investigate the effectiveness of a preventative low-dose of Haloperidol to prevent delirium in patients undergoing a esophagectomy, pneumonectomy or thoracotomy.
- Conditions
- Delirium, Cognitive Impairment, Post-traumatic Stress Disorder, Depression
- Trial name
- PE-POD (NCT02213900)
- Testing
- Haloperidol
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Indiana University
Posttraumatic Stress Disorder
GAMBIT Task With PTSD and Healthy Control Participants
This is a pilot study of a digital training task called GAMBIT. This study will be the first to examine potential relationships between GAMBIT task completion and brain circuit flexibility, behavior, and symptoms in participants…
- Trial name
- GAMBIT (NCT05313334)
- Testing
- GAMBIT Task
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
HIV Infections, Opioid Use
Trauma Intervention to Optimize PrEP Among Women Who Inject Drugs
The goal of this randomized controlled trial is to test the effectiveness of "TIARAS," a trauma intervention designed to reduce HIV acquisition risk among women who inject drugs (WWID).
- Conditions
- HIV Infections, Opioid Use, Trauma, Psychological
- Trial name
- TIARAS (NCT05192434)
- Testing
- Expressive Writing, Contingency Management
- Where
- United States
- Volunteers
- 219 people
- Sponsor
- Drexel University
Psychological Stress, Coping Skills
Promoting Stress Management and Engagement in Introductory Physics Courses with Mindfulness and Relaxation
This study tests the impact of mindfulness vs. relaxation training on psychological threat and challenge, emotions/emotion regulation, motivation/engagement, and performance among undergraduates enrolled in introductory physics…
- Conditions
- Psychological Stress, Coping Skills, Emotions, Emotion Regulation
- Trial name
- NCT05542498
- Testing
- Mindfulness, Relaxation
- Where
- United States
- Volunteers
- 303 people
- Sponsor
- University of Pittsburgh
Mental Disorder, Child
Early Intervention Skills for Preschool Children With Emotional and Stress Related Disorders
This study is about early intervention for preschool children with emotional and stress related disorders. To develop a set of program that could be used in district hospitals for early intervention of preschool children with…
- Trial name
- NCT02991378
- Testing
- Children's emotional and stress coping program
- Where
- China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
TBI Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder
Veterans' Cognitive Function, Mental Health, and Quality of Life After Hyperbaric Oxygen Therapy
The purpose of this study is to evaluate how hyperbaric oxygen therapy (HBOT) may affect cognitive functioning, post-traumatic stress disorder (PTSD), depression, anxiety, and overall quality of life in veterans. 1.
- Conditions
- TBI Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder, Post Concussive Syndrome
- Trial name
- NCT07214415
- Testing
- Hyperbaric Oxygen Therapy
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Summit Hyperbarics and Wellness
Anxiety Disorders and Symptoms, PTSD and Trauma-related Symptoms
Personalizing Treatment Delivery
Anxiety and anxiety-related disorders frequently co-occur with alcohol use problems resulting in an enormous humanitarian and economic cost to society.
- Conditions
- Anxiety Disorders and Symptoms, PTSD and Trauma-related Symptoms, Alcohol; Use, Problem; Alcohol Use Disorder
- Trial name
- NCT05821634
- Testing
- Personalized intervention condition: Cognitive behavioral therapy skills, Therapeutic control condition: Cognitive behavioral therapy skills, Tracking control condition: Supportive counseling
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Rutgers, The State University of New Jersey
Posttraumatic Stress Disorder, Major Depressive Disorder
Risk and Resiliency Factors in the RCMP: A Prospective Investigation
The Royal Canadian Mounted Police (RCMP), like all public safety personnel (PSP), are frequently exposed to potentially psychologically traumatic events that contribute to posttraumatic stress injuries (PTSI).
- Conditions
- Posttraumatic Stress Disorder, Major Depressive Disorder, Panic Disorder, Generalized Anxiety Disorder
- Trial name
- NCT05527509
- Testing
- Emotional Resilience Skills Training (ERST), Active Monitoring
- Where
- Canada
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- University of Regina
PTSD
Study Comparing Two Versus Three Active MDMA-assisted Sessions in U.S. Military Veterans With Chronic PTSD
The goal of this clinical trial is to learn if MDMA-assisted therapy is effective in U.S. military veterans with at least moderate chronic PTSD.
- Trial name
- MPVA6 (NCT04784143)
- Testing
- Midomafetamine, Psychotherapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Resilient Pharmaceuticals
Burnout, Professional, Stress, Psychological
The Effect of Laughter Yoga on Individual and Organizational Outcomes in Nurse Managers
The goal of this clinical trial is to learn if laughter yoga can improve both individual and organizational outcomes in nurse managers.
- Conditions
- Burnout, Professional, Stress, Psychological, Compassion Fatigue, Quality of Life
- Trial name
- NCT07235735
- Testing
- Laughter Yoga Program
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Healthy, Cancer
The Effects of a Meditation Retreat on Healthy Volunteers and Cancer Patients: an fMRI Study
The purpose of this study is to evaluate the effects of a Zen meditation retreat (Sesshin) on psychophysiological parameters in healthy volunteers (regular meditators and non-meditators) and in cancer patients and to observe…
- Trial name
- Sesshin (NCT00878735)
- Testing
- Zen meditation
- Where
- Brazil
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Posttraumatic Stress Disorder
Pilot Study of the Safety and Efficacy of Four Different Potencies of Smoked Marijuana in 76 Veterans With PTSD
This pilot study gathered preliminary evidence of the safety and efficacy of four potencies of smoked cannabis to manage chronic, treatment-resistant PTSD among veterans: (1) High THC/ Low CBD (High THC), (2) Low THC/High CBD…
- Trial name
- NCT02759185
- Testing
- High THC cannabis, High CBD cannabis, THC/CBD cannabis
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Multidisciplinary Association for Psychedelic Studies
Posttraumatic Stress Disorder, PTSD
Clinical Effectiveness Trial of In-Home Cognitive Processing Therapy for Combat-Related PTSD
The primary objective of this study is to evaluate the effectiveness of Cognitive Processing Therapy (cognitive only version; CPT-C) delivered using two different formats in the home setting for the treatment of combat-related…
- Trial name
- NCT02290847
- Testing
- Cognitive Processing Therapy (cognitive only version; CPT-C)
- Where
- United States
- Volunteers
- 172 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Memory Disorders, Mild Cognitive Impairment
A Mobile Informatics Solution to Assist Caregivers in Care Coordination and Monitoring Social Engagement
This study will evaluate the Social Reminder System, a mobile informatics system designed to support persons with memory concerns and their care partners.
- Conditions
- Memory Disorders, Mild Cognitive Impairment, Dementia, Social Isolation
- Trial name
- NCT07773493
- Testing
- Social Reminder System
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Minnesota
Posttraumatic Stress Disorder
TOP Implementation Project
The Veterans Health Administration (VHA) provides care to 3.3 million Veterans living in rural areas, comprising 36% of all VHA enrollees.
- Trial name
- NCT02737098
- Testing
- Enhanced Implementation Strategy, Standard Implementation Strategy
- Where
- 6 sites in United States
- Volunteers
- 544 people
- Sponsor
- VA Office of Research and Development
Chronic Post-Traumatic Stress Disorder, Marijuana Abuse
Short-Term Exposure for PTSD
This study examines how marijuana use affects processes related to recovery from chronic posttraumatic stress disorder (PTSD). Half the participants will be individuals with chronic PTSD and heavy marijuana use and half will be…
- Trial name
- STEP (NCT02874898)
- Testing
- Brief Imaginal Exposure
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Washington
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