Clinical trials: Metabolic Control
Morbid Obesity, Labor Pain
DPE Technique in Labor Epidural for Morbidly Obese Women
The primary purpose of this study is to determine differences in block quality between the "dural-puncture epidural" (DPE) and standard epidural (EPL) techniques for labor analgesia in the morbidly obese patient.
- Trial name
- NCT03074695
- Testing
- Dural puncture epidural (DPE), Standard Epidural (EPL)
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Duke University
Diet, Mediterranean, Health Behavior
Feeding America's Bravest: Mediterranean Diet-Based Interventions to Change Firefighters' Eating Habits
The purpose of this study is to modify the food culture of the fire service by motivating firefighters and their families to incorporate Mediterranean diet principles at work and home through behavior change strategies that…
- Conditions
- Diet, Mediterranean, Health Behavior, Program Sustainability, Program Effectiveness
- Trial name
- NCT02941757
- Testing
- Mediterranean diet Intervention
- Where
- United States
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Gestational Diabetes
Evaluating the Efficacy of GPT-based Nutrition and Diabetic Counseling in Gestational Diabetes Management: A Randomized Controlled Trial (AIM-GDM)
The purpose of this study is to assess whether an AI based counseling service can be beneficial for patients to assist in management of gestational diabetes.
- Trial name
- AIM-GDM (NCT06582719)
- Testing
- GPT-based counseling, Nutritional Counseling
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Healthy
Impact of Protein Content of Ultraprocessed Foods on the Regulation of Energy Balance
Aim of the study is to investigate the effects of high-protein, ultraprocessed foods on the regulation of energy balance in a metabolic chamber.
- Trial name
- NCT05337007
- Testing
- high protein diet, moderate protein diet
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Kiel
Maltreatment
Reduce Childhood Maltreatment and Promote Development
Background (brief): 1. Burden: The uniqueness of each child is tremendously influenced by interaction between nature and nurture during critical period of brain development that promotes foundation of brain architecture through…
- Trial name
- NCT03031236
- Testing
- Psychosocial stimulation, Cognitive behavioral therapy and positive parenting practice
- Where
- Bangladesh
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Overweight, Obesity
A Study Investigating the Safety of RO7795081 and the Effect of RO7795081 on How the Body Processes Pitavastatin and Rosuvastatin in Otherwise Healthy Overweight or Obese Adult Participants
This is a randomized, investigator-and-participant-blind, placebo-controlled, fixed sequence, cross-over, Phase 1 study to investigate the safety, tolerability, and pharmacokinetics of multiple doses of orally administered…
- Trial name
- NCT06982131
- Testing
- RO7795081, Rosuvastatin, Pitavastatin
- Where
- Netherlands
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Meal, Obesity, Morbid
Microstructural Analysis of Ingestive Behavior After Roux-en-Y Gastric Bypass - Pilot
The ability to assess ingestion in fine detail over the time course of a liquid meal allows for comparison of early and late meal features of drinking and may help dissociate manipulations (surgical, neural, pharmacological…
- Conditions
- Meal, Obesity, Morbid, Food Deprivation, Bariatric Surgery
- Trial name
- NCT03747445
- Testing
- Roux-en-Y gastric bypass
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marco Bueter
Menopause, Cognitive Change
PhytoSERM to Prevent Menopause Associated Decline in Brain Metabolism and Cognition
This is a proof-of-concept phase 2 clinical trial to investigate the safety and effect of the phytoestrogenic supplement PhytoSERM on regional brain metabolism by fluorine-18 fluorodeoxyglucose positron emission tomography…
- Conditions
- Menopause, Cognitive Change, Brain Disorder, Metabolic
- Trial name
- NCT05664477
- Testing
- PhytoSERM
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Roberta Brinton
Obesity, Cardiovascular Risk Factor
Healthy Nordic Foods to Prevent Cardiometabolic Risk in Obese Subjects
This project will examine whether long-term consumption of healthy Nordic foods can maintain a healthy weight also after weight loss, and decrease abdominal fat accumulation and cardiometabolic risk.
- Conditions
- Obesity, Cardiovascular Risk Factor, Diet Modification
- Trial name
- NCT03102853
- Testing
- Nordic diet, Control diet
- Where
- Sweden
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lund University
Obesity, Eating Disorders
Internet Weight Control for Bingeing Adolescents
The purpose of this study is to determine if an internet-based intervention designed to reduce binge eating and improve healthy weight regulation skills will result in reductions in binge eating and weight loss, or weight…
- Trial name
- NCT00125112
- Testing
- Internet-based intervention designed to reduce binge eating and improve healthy weight regulation
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Anesthesia, Mechanical Ventilation
VC-AF vs FCV in Obese Patients Undergoing Laparoscopic Surgery
Obesity adversely affects respiratory physiology by reducing lung volumes and compliance and increasing airway resistance and alveolar collapse.
- Conditions
- Anesthesia, Mechanical Ventilation, Obesity
- Trial name
- NCT07875530
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Dyslipidemias
A Study to Evaluate LY3202328 in Overweight Healthy Participants and Dyslipidemia
The purpose of this two-part study is to evaluate the safety and tolerability of the study drug known as LY3202328 in healthy overweight participants in Part A, and those with dyslipidemia (abnormal blood fats) in Part B.
- Trial name
- NCT02714569
- Testing
- LY3202328, Atorvastatin, Simvastatin
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Weight Loss, Wait-List Control
Neurotrophic Indicators of Cognition, Executive Skills, Plasticity, and Adverse Childhood Experiences Study
Adverse childhood experiences (ACEs) are repeatedly shown to predict negative biopsychosocial health outcomes, including obesity.
- Trial name
- NICE SPACES (NCT04076722)
- Testing
- Stress reactivity stimuli
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
Childhood Obesity, Childhood Obesity Pevention
Effectiveness of School-Based Time-Restricted Eating for the Prevention and Control of Obesity in Children
Childhood obesity has become a major global public health challenge. Obesity can not only affects children's physical and mental health during childhood but may also persist into adulthood, significantly increasing the risk of…
- Trial name
- SCHOOL-TRE (NCT07184281)
- Testing
- 12-hour time-restricted eating, health education
- Where
- 2 sites in China
- Volunteers
- 1,380 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Soochow University
Glycemic Control, Insulin Sensitivity
Comparing the Effects of Different Types of Exercise on Glucose Handling
The purpose of the proposed study is to compare the acute effects of different types of exercise modalities on glucose handling in young, healthy males and females.
- Conditions
- Glycemic Control, Insulin Sensitivity, Sex Differences
- Trial name
- NCT06217679
- Testing
- Control Oral Glucose Tolerance Test, Mixed Exercise
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Inflammation, Pregnancy Related
Docosahexaenoic Acid (DHA) Supplementation in High Risk Pregnancies
Purpose: Determine the effects of maternal docosahexaenoic acid (DHA) supplementation during pregnancy on levels of DHA, synaptamide (novel anti-inflammatory metabolite), and inflammatory biomarkers during pregnancy and at…
- Trial name
- NCT04069195
- Testing
- DHA supplement, Corn Oil: Soybean Oil
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Metabolic Syndrome
Whole Soy Replacement Diet on Metabolic Features
Project title: A randomized controlled trial of whole soy diet in place of red/processed meat and high fat dairy products on metabolic features in postmenopausal women Objectives: Metabolic syndrome (MetS) is an escalating public…
- Trial name
- NCT02610322
- Testing
- Whole soy replacement diet, usual diet
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Zinc Deficiency, Child Nutrition Disorders
Daily Zinc Supplement Effect on Prevention of Diarrhea and Acute Respiratory Infections in Children Less Than Five Years
Zinc deficiency in children is a major problem which leads to compromised immunity and accordingly repeated infections. This study aims to investigate the effect of supplementing zinc to decrease the incidence of diarrhea and…
- Trial name
- RCTZ (NCT05002101)
- Testing
- zinc
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Obesity Prevention, Obesity
Effectiveness of Tailored Multichannel Interventions on Weight Loss Among Adolescents: A Randomized Controlled Trial
overweight among adolescents is a public health issue. However, several weight loss interventions were developed and conducted for adolescents.
- Conditions
- Obesity Prevention, Obesity, Overweight Adolescents, Overweight/Obesity, Adolescent
- Trial name
- NCT06767072
- Testing
- Tailored Multichannel interventions
- Where
- Egypt
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- Cairo University
Diabetes Mellitus, Type 2, Cardiovascular Disease
Moderate Alcohol Consumption, Fat and Carbohydrate Metabolism and Insulin Sensitivity
Moderate alcohol consumption is associated with a decreased risk of diabetes type 2. This association could be mediated by an improvement of insulin sensitivity with moderate alcohol consumption.
- Trial name
- NCT00364767
- Testing
- A, B
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- TNO
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