Clinical trials: Metabolic Disorders
Overweight, Obesity
Fruit And Vegetable Or Recreation Prescriptions for UW-Madison Students
This research will use randomized controlled trial (RCT) methodology to assess the feasibility of a prescription for fruit/vegetable CSA shares or exercise by bikeshare on obesity-related outcomes.
- Trial name
- FAVORx (NCT02870322)
- Testing
- Fruit and Vegetable CSA Prescription, Bikeshare Prescription
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Diabetes Mellitus, Type 2, Antioxidative Stress
Dietary Antioxidants and Thiol Disulfide Homeostasis in T2DM
This observational study was planned to determine the relationship between dietary antioxidant intake and thiol disulfide homeostasis of individuals with type 2 diabetes.
- Trial name
- NCT05688631
- Testing
- Dietary antioxidant intake
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Diabetes Mellitus, Type 2, Metformin Adverse Reaction
Metformin Gastrointestinal Intolerance: Measurement of Mitochondrial Complex I
Metformin is associated with a high degree of gastrointestinal intolerance, which limits the effective use of the medication. It is proposed to be an inhibitor of liver mitochondrial glycerophosphate dehydrogenase which results…
- Trial name
- NCT03445702
- Testing
- Metformin
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- St. Louis University
Overweight, Hunger
Water Exercise and Health (WATHEALTH)
Aquatic cycling is becoming more popular as it appears to be more suitable for men and women even with poor physical activity level. Commercial tagline highlight beneficial effect of this activity on weight management.
- Trial name
- WATHEALTH (NCT03978975)
- Testing
- Food intake
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Mucopolysaccharidoses
Validation and Reliability of Iris Cameras in Mucopolysaccharidoses
To assess the reliablity and validity of 2 new iris cameras in the assement of corneal opacification in mucopolysaccharidoses
- Trial name
- NCT05354219
- Testing
- Imaging
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
HIV Seropositivity, Dyslipidemias
COPANA - A09 PCSK 9 Substudy: Impact of Protease Inhibitors on PCSK9 Levels in Naive HIV-Infected Patients
Evaluation of the impact of initiation of protease inhibitor/ritonavir on PCSK9 levels in HIV-infected antiretroviral-naïve patients from the ANRS C09 COPANA cohort.
- Conditions
- HIV Seropositivity, Dyslipidemias, PCSK9
- Trial name
- COPANA (NCT03139630)
- Where
- France
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Franck Boccara
Polycystic Ovary Syndrome, Obesity
Insulin and the Polycystic Ovary Syndrome--Weight Reduction Study
The polycystic ovary syndrome is the leading cause of female infertility in the United States. The disorder affects approximately 6-10% of women of reproductive age.
- Trial name
- NCT00436865
- Testing
- Weight loss
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Iron Deficiency
Effect of Coca-Cola on Iron Absorption
The aim of this project is to measure the effect of Coca-Cola and Diet Coke, relative to mineral water, on non-haem iron absorption.
- Trial name
- NCT00474500
- Testing
- Coca, Cola, Diet Coke
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Quadram Institute Bioscience
Diabetes Mellitus, Type 1
Estrogen and Diabetes
Diabetes has recently been referred to as "the epidemic of the 21st century". The reason why women with type 1 diabetes have a 2-3 fold greater risk of cardiovascular disease (CVD) compared to men with type 1 diabetes is…
- Trial name
- NCT03436992
- Testing
- Antioxidant Cocktail, Resveratrol
- Where
- 2 sites in United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Augusta University
Overeating, Overweight
Testing a Brief Mindful Eating Program
This project evaluated the effects of a brief manualized mindful eating intervention as a treatment for overeating with individuals with overweight and obesity.
- Conditions
- Overeating, Overweight, Obesity
- Trial name
- NCT04531436
- Testing
- Brief mindful eating intervention
- Where
- Canada
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- McGill University
Healthy, Fasting
The Food Effect on Pharmacokinetics of Fixed Dose Combination of Gemigliptin/Dapagliflozin/Metformin in Healthy Volunteers
This is a single dose, randomized, open-label, two-way crossover study to investigate the food-effect bioavailability of the fixed-dose combination of Gemigliptin/Dapagliflozin/Metformin 50/10/1000 mg in healthy volunteers under…
- Conditions
- Healthy, Fasting, Fed
- Trial name
- NCT07396844
- Testing
- Fixed-dose combination of gemigliptin/dapagliflozin/metformin 50/10/1000 mg
- Where
- Thailand
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- LG Chem
Fasting, Fed
Development of the Leeds Food Preference Questionnaire in Spanish
The Leeds Food Preference Questionnaire (LFPQ) is a computer-based task used to measure reward responses and preferences for images of food.
- Trial name
- ES-LFPQ (NCT05837572)
- Testing
- Standardized meal
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Iron-deficiency, Menorrhagia
Measuring Menstrual Iron Loss Using the Iron Isotope Dilution Technique
It is very difficult to quantify menstrual blood loss, the reference method is a tedious one. This is a problem, as it is not conducive to objectively measuring menstrual blood loss and understanding the contribution of menstrual…
- Conditions
- Iron-deficiency, Menorrhagia, Anemia
- Trial name
- MBL_Loss (NCT05788172)
- Testing
- Iron isotope dilution, Alkaline hematin method
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Isabelle Herter-Aeberli
Obesity
Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Food Effect of NO-13065 in Healthy and Obese Adult Subjects
This clinical trial is the first-in-human study of NO-13065. The purpose of this phase 1 study is to assess the safety and tolerability of single and multiple ascending oral doses and food effect of NO-13065 in healthy and obese…
- Trial name
- NCT04838639
- Testing
- NO-13065
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Factory, Inc.
Obesity
Baby Nutrition and Physical Activity Self-Assessment for Child Care (NAP SACC) Intervention Study
This study will evaluate the efficacy of a six-month-long intervention in improving the nutrition and physical activity environments of child care centers serving racially and ethnically diverse children from birth to two years…
- Trial name
- NCT01890681
- Testing
- Baby NAP SACC, Back to Sleep
- Where
- 3 sites in United States
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Chronic Kidney Diseases, Proteinuria
Efficacy of On-venous Laser Irradiation of Blood on Diabetes Kidney Disease Patients
The single center, randomized, assessor- and participant-blind, controlled, cross-over on-venous laser irradiation of blood clinical trial was performed to analyze patients with DKD.
- Conditions
- Chronic Kidney Diseases, Proteinuria, Diabetes Mellitus
- Trial name
- NCT06588465
- Testing
- On-venous Laser Irradiation of Blood, low dose On-venous Laser Irradiation of Blood
- Where
- Taiwan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Obesity in Pregnancy
Best Start - Weight Management During Pregnancy
The investigators know that being overweight during pregnancy increases the health risks to both mum and baby. There is good evidence that diet or exercise, or both, during pregnancy can reduce excessive weight gain.
- Trial name
- NCT03875300
- Testing
- Foodwise in Pregnancy
- Where
- 4 sites in United Kingdom
- Volunteers
- 526 people, healthy volunteers welcome
- Sponsor
- Cwm Taf University Health Board (NHS)
Metabolic Disease
Characterization of Human Intestinal Macrophages in Metabolic Disease
This is a prospective, observational study aiming at improving the understanding of the pathophysiology of metabolic disease. As inflammation has been recognized as a key characteristic of metabolic disease but its starting point…
- Trial name
- iMAC (NCT03796000)
- Testing
- tissue samples, blood and stool sample
- Where
- Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Diabetes
Future of Beta Cells in Adults With Genetic Abnormality Behind Neonatal Diabetes
The main objective of this study is to evaluate Beta cells in patients with a neonotal diabetes linked to a genetic abnormality Metabolic caracteristics will described using a transversal cohort study.
- Trial name
- GLUCONEO (NCT02072551)
- Where
- France
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dietary Habits, Risk Factor, Cardiovascular
Sodium Intake in Ecuadorian Population
This study is aim to determine the sodium intake in Ecuadorian population that is an unknown information at present. For that, 24h urine samples will be collected from 130 subjects working either at tue USFQ or HDLV to measure…
- Conditions
- Dietary Habits, Risk Factor, Cardiovascular, Nutritional Disorder
- Trial name
- NCT03154502
- Testing
- Urinary sodium excretion
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Universidad San Francisco de Quito
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