Clinical trials: Metabolic Parameters
Computer Simulation, Energy Expenditure
Modelling of Energy Expenditure From Heart Rate, Accelerometry and Other Physiological Parameters
At this time, 24h energy expenditure is rarely assessed under free-living conditions for specific individuals because of the lack of cheap and accurate software/materials to record the energy expenditure.
- Conditions
- Computer Simulation, Energy Expenditure, Energy Metabolism
- Trial name
- Modelheart (NCT01209572)
- Testing
- calorimetric chamber, Free living conditions
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Vitamin A Deficiency, Malaria
Assessing Model Parameters for Applying the Retinol Isotope Dilution (RID) Method
For assessing body retinol pools in preschool children, it is recommended that a blood sample is taken 14-21 days after isotope dosing. During this period, dietary intake of vitamin A should be controlled.
- Conditions
- Vitamin A Deficiency, Malaria, Inflammation
- Trial name
- SUPERKID (NCT02996513)
- Testing
- Retinol Isotope Dilution (RID)
- Where
- Nigeria
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Obesity
Effectiveness of Rice Germ Supplementation on Body Composition, Metabolic Parameters, Satiating Capacity and Amino Acid Profiles in Obese Postmenopausal Women
Rice germ (RG) may be a safe and effective dietary supplement for obesity in menopause, considering its high protein content and considerable amounts of essential amino acids, good fatty acids, and fiber.
- Trial name
- NCT04695418
- Testing
- Rice Germ
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Azienda di Servizi alla Persona di Pavia
Obesity
Effects of Synbiotics on Obesity
Synbiotics are a combination of probiotics and prebiotics that can promote the survival of probiotics in the gut. Probiotics utilize prebiotics to produce various metabolites beneficial to human health, such as short-chain fatty…
- Trial name
- NCT06578143
- Testing
- Synbiotics
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Leeuwenhoek Laboratories Co. Ltd.
Obesity
Effect of Olvanil Supplementation on Clinical, Biochemical and Anthropometric Parameters in Obese Adults
Capsaicinoids are defined as alkaloid compounds of the Capsicum genus, they are characterised by the pungent flavor of chili. About the Capsicum genus, there are more than 20 known compounds, including dihydrocapsaicin…
- Trial name
- NCT05857306
- Testing
- Olvanil
- Where
- 2 sites in Mexico
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Guadalajara
Obesity
Effects of the GOLO Weight Management Program With and Without Release Supplement on Weight and Metabolic Parameters in Subjects With Obesity
This randomized, double-blind placebo-controlled study was intended to measure the effects of the GWMP with Release supplement versus GWMP with placebo supplement in a representative group of obese subjects with or without…
- Trial name
- NCT03842501
- Testing
- Release Supplement
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Golo
Cardiovascular Diseases, Glucose Metabolism Disorders
Effects of Hazelnuts and Cocoa on Metabolic Parameters and Vascular Reactivity
This study aims to assess the effects of hazelnuts, cocoa, and the combination of both on vascular reactivity and metabolic profile.
- Trial name
- NCT02845622
- Testing
- Hazelnut, Cocoa, No hazelnuts / No cocoa
- Where
- Italy
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Ospedale San Donato
Diabetes Mellitus
Comparative Measurement of Microcirculation and Other Parameters With the Vital USA VitalDetect™ in Patients With Diabetes Mellitus Type 1 and Type 2 Versus Healthy Participants
The purpose of this clinical study is to optimize the measurement algorithm of the Vital USA VitalDetectTM in measuring the microcirculating blood flow.
- Trial name
- NCT06063759
- Testing
- VitalDetect
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sciema UG
Obesity & Overweight, Morbid Obesity
Investigation of the Effects of Whole Body Vibration Application on Muscle Functional Level, Physical Fitness and Respiratory Parameters After Bariatric Surgery
The aim of this study was to investigate the effects of whole body vibration on muscle functional level, physical fitness and respiratory parameters after bariatric surgery.
- Conditions
- Obesity & Overweight, Morbid Obesity, Morbid Obesity Requiring Bariatric Surgery
- Trial name
- NCT07602959
- Testing
- Resistance Training, Whole Body Vibration, Control Group
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Type 2 Diabetes Mellitus
Study to Evaluate the Potential Pharmacokinetic Interaction and Pharmacodynamic Effects on Renal Parameters of Bumetanide (1mg) and Dapagliflozin (10 mg) When Co-administered in Healthy Subjects
To assess the potential pharmacokinetic (PK) interactions of bumetanide and dapagliflozin following multiple doses of 1 mg bumetanide and 10 mg dapagliflozin in healthy subjects
- Trial name
- NCT00930865
- Testing
- Bumetanide, Dapagliflozin
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Overweight, Obesity
Vitamin D Effects in Overweight Patients
The purpose of the study is to investigate in overweight patients who are on a telemedically guided weight loss program the influence of a daily vitamin D supplement on weight loss and body composition, selected inflammation…
- Trial name
- SMART (NCT00493012)
- Testing
- vitamin D
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Heart and Diabetes Center North-Rhine Westfalia
Cardiometabolic Syndrome
Effects of Berberine on Cardiometabolic Outcomes
Cardiovascular disease, type 2 diabetes mellitus and associated diseases combined are the leading health burden and cause of mortality worldwide; therefore, the necessity for an intervention is paramount.
- Trial name
- NCT07541898
- Testing
- Berberine
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Central Lancashire
Endometriosis, Bone Density
BMD Alterations and Bone and Muscle Parameters During Menstrual Cessation With GnRH
The investigators aim to investigate the effect of menstrual cessation in women with endometriosis treated with GnRH analogs for 6 months on bone mineral density and bone and muscle metabolism parameters and subsequently the…
- Conditions
- Endometriosis, Bone Density, Muscle, Bone Metabolism
- Trial name
- NCT04203212
- Testing
- Goserelin Acetate
- Where
- Greece
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- 424 General Military Hospital
Covid19, Diabetes Mellitus, Type 2
Blood Sample Measurements and Physical Activity Levels in Type II Diabetes and/or COVID-19
It is known that COVID-19 has a more negative clinical course and causes higher degrees of morbidity and mortality in case of COVID-19 in diabetic patients.
- Trial name
- NCT04695158
- Testing
- COVID-19 group (Group I), Type II Diabetes Mellitus and COVID-19 group (Group II)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Izmir Bakircay University
Diabetes Mellitus, Type 2
A Study To Evaluate The Effects Of PF-05175157 In Healthy Volunteers
The primary purpose of this study is to evaluate pharmacodynamics of single oral doses of PF-05175157 in a dose-dependent fashion in healthy volunteers
- Trial name
- NCT01537497
- Testing
- PF-05175157
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Pfizer
Osteopenia, Osteoporosis
Time-specific Exercise in Circadian Context
The project aims to explore the mechanisms, by which physical activity can support healthy ageing and decrease the negative impact of ageing on the circadian system, musculoskeletal system and immunity.
- Conditions
- Osteopenia, Osteoporosis, Aging
- Trial name
- CAEx (NCT06746649)
- Testing
- Combined training
- Where
- Slovakia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Comenius University
Polycystic Ovary Syndrome
The Effect of Cinnamon Extract on Insulin Resistance Parameters in Polycystic Ovary Syndrome: A Pilot Study
The purpose of this study is to determine whether oral cinnamon extract are effective in reducing insulin resistance parameters in women with polycystic ovary syndrome.
- Trial name
- NCT00331279
- Testing
- Oral Cinnamon Extract
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Columbia University
HELICOBACTER PYLORI INFECTIONS, Metabolic Syndrome
Eradication of Helicobacter Pylori Improves Metabolic Syndrome Through Modulation of Gut Microbiota.
The Role of Gut Microbiota in the Mechanism of Helicobacter pylori Eradication-Induced Amelioration of Metabolic Syndrome-Related Parameters Study Sponsor: Nanjing First Hospital Principal Investigator: Dr.
- Trial name
- NCT07306988
- Testing
- Vonoprazan-Amoxicillin Dual Therapy, Vonoprazan-Amoxicillin with Bifidobacterium tetravaccae, Vonoprazan-Amoxicillin with Berberine
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Metabolic Syndrome
Effects of Oral Fruit Concentrate Supplementation on Cardiometabolic Parameters.
Cardiovascular disease, type 2 diabetes mellitus and associated diseases combined are the leading health burden and cause of mortality worldwide; therefore, the necessity for an intervention is paramount.
- Trial name
- NCT04177238
- Testing
- Fruit concentrate - either cherry or blueberry
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Central Lancashire
Effect of Omega-3 Fatty Acid Supplementation Physical Fitness
Effect of 12 wk of Omega-3 FA Supplementation on Metabolic and Physical Health Parameters in Older Adults
The biological membranes that surround a cell and its organelles are important to the overall function of the cell. Fatty acids are the main structural components of a membrane, and the presence of certain fatty acids can alter a…
- Trial name
- NCT01734538
- Testing
- Omega-3 Complete
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Guelph