Clinical trials: Metabolic Risk Factors
Diabetic Nephropathy Type 2 - Uncontrolled, Diabetes Mellitus, Type 2
Mixed Methods Study of Health-Related Social Needs in African American Adults With Chronic Kidney Disease and Type 2 Diabetes Mellitus
The overarching goal of this study is to understand facilitators and barriers to self-care, develop and refine a culturally tailored intervention to improve clinical outcomes, quality of life (QOL), and self-care behaviors in…
- Conditions
- Diabetic Nephropathy Type 2 - Uncontrolled, Diabetes Mellitus, Type 2, Chronic Kidney Diseases
- Trial name
- NCT05692388
- Testing
- Patient and Community Stakeholder Interviews, Cross-sectional Study Participants, Focus Groups and Intervention Mapping
- Where
- United States
- Volunteers
- 330 people
- Sponsor
- Medical College of Wisconsin
Chronic Kidney Diseases, Diabetes Mellitus
Prevalence of Chronic Kidney Disease (CKD) and Risk Factors in Sub-Saharan Africa
Prospective cross-sectional study at the outpatient clinic (OPC) of the Bagamoyo District Hospital (BDH) in Tanzania. Assessment of basic epidemiological data (Point prevalence and risk factors) on CKD with simple clinical…
- Conditions
- Chronic Kidney Diseases, Diabetes Mellitus, Hypertension, Tuberculosis
- Trial name
- RenalOne (NCT03458338)
- Testing
- estimated glomerular filtration rate and albuminuria
- Where
- Switzerland
- Volunteers
- 1,006 people
- Sponsor
- University Hospital, Basel, Switzerland
Cardiovascular Disease, Metabolic Syndrome
Canola Oil Multi-center Intervention Trial II
Building on the findings from the investigators previous study, COMIT I, the purpose of the COMIT II study is to supplement the DEXA measurement of body composition with a supplementary DEXA measurement of visceral adipose tissue…
- Trial name
- COMITII (NCT03054779)
- Testing
- Canola Oil, High oleic acid canola oil, Western diet oil combination
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Penn State University
Abdominal Obesity
Effects of Exercise Modality on Abdominal Obesity and Health Risk Factors in Older Men and Women
The prevalence of abdominal obesity in the elderly is increasing at alarming rates and thus, requires immediate attention. By comparison to younger adults, obesity reduction in the elderly presents a unique challenge and requires…
- Trial name
- NCT00520858
- Testing
- Resistance Exercise (RE), Aerobic Exercise (AE), Resistance and Aerobic Exercise (RAE)
- Where
- Canada
- Volunteers
- 145 people
- Sponsor
- Queen's University
Type 2 Diabetes
The Effect of Nexium and Probiotics on Insulin Secretion and Cardiovascular Risk Factors in Patients With Type 2 Diabetes
To test the effect of Nexium and probiotics on insulin secretion and cardiovascular risk factors on type 2 diabetic patients. Study Hypothesis: 1.
- Trial name
- Nexium (NCT00699426)
- Testing
- nexium, Yoghurt
- Volunteers
- 41 people
- Sponsor
- Lise Tarnow
Obesity
Investigation of Waist Circumference and Waist/Hip Ratio as a Predictive Risk Factor for Morbidity and Mortality After Colorectal Surgery
Despite advances in surgical technique, preoperative patient evaluation and post-operative care, elective colorectal surgery carries a risk of mortality of approximately 2% and a morbidity rate ranging from 20-40%.
- Trial name
- NCT01737515
- Testing
- Abdominal waist and hip circumference
- Volunteers
- 1,415 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Type II Diabetes Mellitus
Rosiglitazone and Exercise in Patients With Type 2 Diabetes Mellitus
The aim of the present study is to investigate the influence of systemic exercise, rosiglitazone administration and combined pharmaceutical and lifestyle intervention on cardiovascular risk factors
- Trial name
- NCT00306176
- Testing
- Rosiglitazone
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Cardiovascular Disease
Cardiovascular Risk Factors, Lipid Metabolism and Oxidative Stress
Cardiovascular diseases belong to the major causes of mortality in western populations, and atherosclerosis is the lesion responsible for clinical events, such as acute myocardial infarction and stroke.
- Trial name
- NCT01213303
- Where
- 2 sites in Italy
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Insulin Resistance
Prevalence of IR in Overweight and Obese Adolescents
The aim of this study is to determine the prevalence of Insulin Resistance (IR) among overweight and obese adolescents using HOMA-IR scores and identify lifestyle risk factors in the IR and Non-IR group.
- Trial name
- IR (NCT05810883)
- Testing
- Blood Tests; Serum Fasting Insulin and Glucose
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Metabolic Syndrome, Atherosclerosis
Risk Factor Analysis for Developing Metabolic Syndrome in Korean Adults
In Asia, the prevalence of metabolic syndrome have been dramatically increased. Therefore, the investigators intend to the collect the blood sample, laboratory, anthropometric, and body composition parameters prospectively to…
- Trial name
- NCT01594710
- Where
- South Korea
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Korea University
Microalbuminuria, Microalbuminuria /Creatinine Ratios ACR
New Taipei City 888 Digital Medical AI Platform for Prevention and Care of the Three Highs and Cardio-Renal-Vascular Diseases
Non-communicable diseases (NCDs), or chronic diseases, are a major public health burden globally and in Taiwan, and control of the "three highs" (hypertension, dyslipidemia, and hyperglycemia) is a national priority.
- Conditions
- Microalbuminuria, Microalbuminuria /Creatinine Ratios ACR, Cardiovascular Disease Risk Factor, Cardiovascular Disease Prevention
- Trial name
- DIGICARE-DREAM (NCT07588256)
- Testing
- Interactive digital modules, Antihypertensive Medication Management
- Where
- Taiwan
- Volunteers
- 4,162 people
- Sponsor
- New Taipei City Medical Association
Glycemia, Hypertension
Effect of PATient Education Related to CV Risk factOrs in Type 2 Diabetes Mellitus(Patrol).
This study will address the proportion of achievement patients in treatment target goal on glycemic control, hypertension and hyperlipidemia according to ADA 2008 guideline, among outpatients coming to the Korean primary care…
- Conditions
- Glycemia, Hypertension, Hyperlipidemia
- Trial name
- PATROL (NCT00891124)
- Where
- 7 sites in South Korea
- Volunteers
- 4,045 people
- Sponsor
- AstraZeneca
Cardiovascular Risk Factor
Program of Physical, Nutritional and Psychological Activities With Overweight Schoolchildren
Obesity has been considered as one of the primary factors for the development of pathologies and cardiovascular risk factors. In the child it has been mediator for the development of these comorbidities still in childhood, in the…
- Trial name
- PANPES (NCT03041142)
- Testing
- Interdisciplinary intervention, Routine
- Volunteers
- 33 people
- Sponsor
- Universidade Federal do vale do São Francisco
Obesity, Overweight
Method-of-Use Study Assessing the Effect of Naltrexone Sustained Release (SR)/ Bupropion SR on Body Weight and Cardiovascular Risk Factors in Overweight and Obese Subjects
The purpose of this Phase 3b study is to assess the effects of combination therapy with naltrexone SR/bupropion SR (NB) used in conjunction with a comprehensive lifestyle intervention (CLI) and in a manner consistent with its…
- Trial name
- NCT01764386
- Testing
- NB, CLI, Usual Care
- Where
- 15 sites in United States
- Volunteers
- 242 people
- Sponsor
- Orexigen Therapeutics, Inc
Diabetes Mellitus, Glucose Intolerance
Prevalence of Glucose Intolerance and Risk Factors in Ethiopian Immigrants in Israel; Follow-up Study.
High risk population: Screening for impaired glucose tolerance.
- Trial name
- NCT01402362
- Where
- Israel
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Obesity and Cardiovascular Risk
A Phase 2 Study to Evaluate the Pharmacodynamics, Safety and Tolerability of BGE-102 in Participants With Obesity and Cardiovascular Risk Factors
The purpose of this study is to learn about the effects of BGE-102 on blood biomarkers including hsCRP, which is a lab value used to measure inflammation.
- Trial name
- QUELL-CV (NCT07656727)
- Testing
- Oral BGE-102
- Where
- 17 sites in United States, Puerto Rico
- Volunteers
- 160 people
- Sponsor
- BioAge Labs, Inc.
Mitral Regurgitation, Computed Tomography
Atrial Fibrillation Risk After Miniinvasive Mitral Valve Repair
This retrospective cohort study investigates how CT-derived tissue quality parameters, serving as markers of metabolic status, predict post-operative atrial fibrillation risk in patients undergoing minimally invasive mitral valve…
- Conditions
- Mitral Regurgitation, Computed Tomography, Atrial Fibrillation
- Trial name
- NCT06707506
- Volunteers
- 114 people
- Sponsor
- Nemocnice AGEL Trinec-Podlesi a.s.
Elevated Triglycerides, Cardiovascular Risk Factor
Effects of Omega-3 Docosapentaenoic Acid on Lipids and Other Risk Factors for Cardiovascular Disease
Elevated plasma triglycerides (TG) are due to an excess of TG-rich lipoproteins of several different types, most commonly of very-low-density lipoproteins (VLDL), but also intermediate-density lipoproteins (IDL, or VLDL…
- Trial name
- DPA (NCT04088240)
- Testing
- DPA enriched n-3, n-3 control
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Shoulder Tendinopathy, Metabolic Alterations
Nutrition Impact on PRGF Treatment for Tendinopathy
Given the close correlation reported in the literature between onset and progression of tendon pathology in subjects affected by the alteration of metabolic disorders such as obesity, diabetes mellitus and lipidic metabolic…
- Trial name
- NUTRITENDON (NCT06536582)
- Testing
- Platelet rich growth factor injection (autologous product)
- Where
- Italy
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Osteoporosis
Study on the Predictive Value of the Natural Calcium Isotope Ratio in Urine and Serum for the Diagnosis of Osteoporosis
The study aims at investigating whether the natural calcium isotope ratio (δ44/40Ca) in urine and serum differs between postmenopausal women aged 50 to 75 years suffering from osteoporosis and a healthy control group and whether…
- Trial name
- NCT02967978
- Where
- Germany
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Clinical Research Center Kiel GmbH
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