Clinical trials: Metoclopramide
Migraine, Headache
Magnesium Versus Prochlorperazine Versus Metoclopramide for Migraines
This investigation describes a proposed clinical trial that will evaluate the relative efficacy of intravenous magnesium sulfate for the treatment of migraine compared to intravenous metoclopramide (Reglan) and intravenous…
- Trial name
- MAGraine (NCT05967442)
- Testing
- Magnesium Sulfate, Metoclopramide 10mg, Prochlorperazine (Compazine) Injection
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Opioid Induced Pharyngeal and Esophageal Dysfunction
Opioid Effects on Swallowing and Esophageal Sphincter Pressure
The purpose of this study is to determine whether a dopamine receptor antagonist metoclopramide can counteract opioid induced effects on esophageal motility and lower esophageal sphincter.
- Trial name
- NCT01191645
- Testing
- naloxone, remifentanil, Sodium Chloride
- Where
- Sweden
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Infant, Newborn, Diseases
Electrogastrography (EGC) in Premature Infants With Feeding Intolerance
Serial EGC measurements in premature infants attempting to correlate EGC measurements with signs of feeding intolerance and response to metoclopramide therapy.
- Trial name
- NCT00008736
- Testing
- metoclopramide
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Migraine Headaches, Nausea
Haldol/Diphenhydramine Versus Metoclopramide/Diphenhydramine for Treatment of Acute Headache in the ED: A RCT
Haloperidol is known to be a safe alternative medication to control difficult pain, and has been shown effective when compared to placebo for controlling headaches.
- Conditions
- Migraine Headaches, Nausea, Restlessness
- Trial name
- NCT02098499
- Testing
- Haloperidol, Metoclopramide 10mg, Diphenhydramine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth
Bariatric Surgery Candidate, Perioperative Complication
Effects of Ondansetron, Metoclopramide and Granisetron on Perioperative Nausea and Vomiting in Patients Undergone Bariatric Surgery
Post-operative nausea and vomiting (PONV) is one of the leading causes of patient morbidity after laparoscopic bariatric surgeries.
- Conditions
- Bariatric Surgery Candidate, Perioperative Complication, Nausea, Vomiting, Postoperative
- Trial name
- PONV (NCT05087615)
- Testing
- Metoclopramide, Ondansetron, Metoclopramide and Ondanteron
- Where
- Iran
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Emesis, Postoperative, Maxillofacial Abnormalities
Effects of Antiemetic Agents in Orthognathic Surgery Patients
In an effort to prevent or treat consistently high rates of PONV following maxillofacial operations, several medications, techniques and multimodal protocols have been studied.
- Trial name
- NCT06454825
- Testing
- Intravenous drug
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Breastfeeding
Maxolon to Improve Breastmilk Supply in Diabetic Women: a Randomised Controlled Trial
Early use of oral maxalon can hasten and improve the establishment of breastfeeding in diabetic mothers after preterm and term deliveries.
- Trial name
- Maxalon (NCT00477776)
- Testing
- Metoclopramide (Maxolon)
- Where
- Singapore
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Aspiration Prophylaxis
Effect of Intravenous Metochlopramide Prophylaxis on Gastric Volume
Gastric fluid volume and pH in patients undergoing cesarean section are essential considerations for general anesthesia (GA). Increased gastric volume and low pH of gastric contents could predispose the risk of aspiration…
- Trial name
- NCT04609124
- Testing
- Abdominal ultrasound evaluation of antral area
- Where
- Egypt
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Assiut University
Poor Responders in IVF
Efficacy of Metoclopramide in Poor Ovarian Response IVF Patients
Poor ovarian response population of ART are considered the biggest challenge for providers. Hitherto, no one protocol has been proven to be effect in this subgroup of IVF patients.
- Trial name
- NCT03560583
- Testing
- Metoclopramide
- Where
- Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Barzilai Medical Center
Breastfeeding
Metoclopramide to Aid Establishment of Breastfeeding:a Randomised Controlled Trial
Hypothesis: Early use of oral metoclopramide can hasten and improve the establishment of lactogenesis II in mothers after preterm and term deliveries.
- Trial name
- NCT00264719
- Testing
- Metoclopramide (Maxolon)
- Where
- Singapore
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Drug Metabolism, Poor, CYP2D6-RELATED
Pharmacogenetic Factors and Side Effects of Metoclopramide and Diphenhydramine
Pharmacokinetic of Metoclopramide (MCP) in correlation to polymorphisms of CYP2D6 and Dopamine-D2-Receptor. Pharmacokinetic of Diphenhydramine (DPH) in correlation to polymorphisms of CYP2D6
- Trial name
- MalD (NCT01289938)
- Testing
- Diphenhydramine, Metoclopramide
- Where
- Germany
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Matthias Schwab
Migraine Disorders
Effect of Metoclopramide Versus Sumatriptan for Emergency Department Treatment of Migraine Headache
The purpose of this study is to determine which drug makes lower migraine headache
- Trial name
- NCT01791400
- Testing
- metoclopramide, injection,20mg, one time, Sumatriptan, injection, 6 mg, one time
- Where
- Iran
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Duration of Labour
Metoclopramide Versus Hyoscine Butylbromide in Shortening Duration of First Stage of Labour
BACKGROUND Prolonged labour can lead to increased maternal and neonatal mortality and morbidity. The risk for complications of prolonged labour is more in poor resource settings.
- Trial name
- NCT05222646
- Testing
- Metoclopramide
- Where
- Nigeria
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Uwakwe Emmanuel Chijioke
Peripheral Vertigo
Comparison of Efficacy of Metoclopramide , Promethazine and Prochloroperazine in the Treatment of Vertigo.
Background: Vertigo as acute symptom seem to be one of most common presentation in ED, can be treated in ED with multiple medication .
- Trial name
- BBPVOMSBAFH (NCT05586763)
- Testing
- Metoclopramid ( 10mg), IM promethazine (25mg) , IM prochloroperazine( 12.5mg)
- Where
- Oman
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Oman Medical Speciality Board
Pregnancy, PONV
Efficacy of Prevention for Postoperative Nausea and Vomiting After Intrathecal Morphine in Cesarean Section
Post-operative nausea and vomiting are the major complications after spinal anesthesia with intrathecal morphine, therefore antiemetic drugs should be administered for best satisfaction of anesthesia to prevent these…
- Trial name
- NCT00892996
- Testing
- dexamethasone, dexamethasone 5 mg
- Where
- Thailand
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Nausea and Vomiting, Postoperative
Granisteron Versus Metoclopramide in Laparoscopic Cholecystectomy
Study aims at comparing the effect of granisteron with that of metoclopramide in patients undergoing lab cholecystectomy
- Trial name
- NCT04899817
- Testing
- Granisetron
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Gastroesophageal Reflux Disease, Diabetic Gastroparesis
Improving Metoclopramide Prescribing Practices at Penn Through a Physician-targeted Intervention
The investigators hypothesized that: 1) an intervention targeted at the prescribing physician would increase the rate of a metoclopramide discontinuation among patients prescribed the medication for questionable or unclear…
- Trial name
- NCT01126034
- Testing
- intervention letter
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Primary Headaches (Includes Migraines, Tension, Cluster Headaches)
Droperidol Versus Metoclopramide + Diphenhydramine for the Treatment of Primary Headaches
The purpose of this study is to determine if droperidol is equally as effective as metoclopramide for treatment of primary headaches in the Emergency Department.
- Trial name
- NCT01406860
- Testing
- Droperidol, Metoclopramide + diphenhydramine
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Acute Mountain Sickness, High Altitude Headache
Comparison of Metoclopramide and Ibuprofen for the Treatment of Acute Mountain Sickness
The objective of this study is to determine the efficacy of metoclopramide in relieving the symptoms of Acute Mountain Sickness (AMS).
- Trial name
- NCT01522326
- Testing
- Ibuprofen, Metoclopramide
- Where
- Nepal
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Labour Duration and Metoclopramide
Metoclopramide and the Length of First Stage of Labor , a Randomized Controlled Trial
Reducing the length of labor is a highly desirable goal of intrapartum care, both from a perspective of maternal and fetal well-being and for the providers of the birth services.
- Trial name
- NCT04969120
- Testing
- Metoclopramide 10mg
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University