Clinical trials: Microbiological Study
Periodontitis, Probiotics
Effects of Probiotic Therapy in the Treatment of Periodontitis.
The aim of this study is to evaluate the effect of the probiotic therapy as an adjunct to non-surgical periodontal treatment in patients diagnosed with Generalized Chronic Periodontitis.
- Trial name
- NCT03408548
- Testing
- Scaling root planning, Probiotic
- Where
- Brazil
- Volunteers
- 41 people
- Sponsor
- University of Sao Paulo
Dental Caries
Phase 2 Study to Evaluate the Microbiology and Safety of C16G2 Administered to Adult and Adolescent Dental Subjects
The purpose of this study is to evaluate if C16G2 Gel administered over a certain period of time either with a toothbrush or a custom dental tray can effectively kill bacteria in the mouth that cause dental cavities.
- Trial name
- NCT02594254
- Testing
- C16G2 Gel
- Where
- 10 sites in United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Armata Pharmaceuticals, Inc.
Blepharospasm, Hemifacial Spasm
Post Marketing Surveillance Study of Dysport
The purpose of this study is to provide further information regarding the risks and benefits of Dysport in marketed indications.
- Conditions
- Blepharospasm, Hemifacial Spasm, Cervical Dystonia, Spasmodic Torticollis
- Trial name
- NCT00210431
- Where
- 36 sites in France, Germany and 1 more
- Volunteers
- 783 people
- Sponsor
- Ipsen
Periodontal Disease
Study on Biomarkers of Periodontitis and Type 2 Diabetes Mellitus in Males and Females 30 - 70 Years of Age
The purpose of this study is to learn about the interactions of markers of type 2 diabetes (T2DM) and periodontitis (PD). Study VPE00001 is a multi-center cross-sectional study.
- Trial name
- NCT06582056
- Testing
- Investigational Procedure
- Where
- 4 sites in United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Urogynaecology
A Study of the Effect of Antibiotics on the Microbiology of the Bladder in Patients With Overactive Bladder
The concept of organisms living on or in the human body without causing overt signs of an infection is common in medicine and has been termed a microbiome.
- Trial name
- NCT02536872
- Testing
- None - this is a prospective observational study. Patients will be prescribed their usual treatment (antibiotics) and the effect on urine studied
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Medway NHS Foundation Trust
HELICOBACTER PYLORI INFECTIONS
Feasibility Study to Diagnose Helicobacter Pylori in the Paediatric Population Using Non-invasive Fecal Analysis
Helicobacter pylori infection is a widespread bacterial disease affecting nearly half of the world's population. In children, the infection displays distinct features versus adults, with lower prevalence, variable symptoms, and…
- Trial name
- HEPYCA (NCT07083804)
- Testing
- Gastric biopsies, Stool sampling
- Where
- France
- Volunteers
- 188 people
- Sponsor
- Poitiers University Hospital
Chlorhexidine, Gingivitis
Clinical and Microbiological Comparison of 0.12% CHX and 0.05% CHX+0.05%CPC Mouthwashes in TPS Patients
The present study compares the effectiveness of two mouthwash formulations (0.12% CHX and 0.05% CHX+0.05%CPC) in reducing gingival inflammation and microbial colonization in individuals with gingivitis and in preventing…
- Conditions
- Chlorhexidine, Gingivitis, Periodontitis, Cetylpyridinium Chloride
- Trial name
- NCT06411522
- Testing
- Mouthwash containing 0.12% CHX (Chlorhexidine), Mouthwash containing 0.05% CHX (Chlorhexidine) and 0.05% CPC (Cetylpyridinium Chloride)
- Where
- Italy
- Volunteers
- 72 people
- Sponsor
- University of Siena
Cirrhosis Due to Hepatitis B, Cirrhosis Due to Hepatitis C
Endoscopic and Microbiological Assessment of the Effect of Carvedilol Combined With Berberine on GOV in Cirrhosis
Carvedilol has been shown to be more potent in decreasing portal hypertension to propranolol. A lot of studies have shown that the imbalance of flora and the progress of portal hypertension are mutually causal.
- Conditions
- Cirrhosis Due to Hepatitis B, Cirrhosis Due to Hepatitis C, Gastroesophageal Varices
- Trial name
- CABER (NCT04543643)
- Testing
- Carvedilol, Berberine
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Tianjin Second People's Hospital
Borrelia Recurrentis Infection
Study of the Clinical, Microbiological and Epidemiological Characteristics of Recurrent Imported Borreliosis Confirmed by the CNR Borrelia
Recurrent borreliosis (RB) is a bacterial infection transmitted by ticks or lice. These infections occur in both temperate and tropical regions, but are rare in Australia and Antarctica.
- Trial name
- BORRECUR (NCT07335965)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Strasbourg, France
Otitis Media
Study Evaluating Microbiological Analysis of Spontaneous Draining Acute Otitis Media
Describe the patient population and bacterial microbiology of pediatric patients presenting with spontaneous draining acute otitis media
- Trial name
- NCT00768534
- Where
- Germany
- Volunteers
- 2,138 people
- Sponsor
- Pfizer
Gingivitis, Periodontitis
OSE as a Pre-procedural Mouth Rinse: A Clinical and Microbiological Study.
Periodontal disease- Inflammatory, Multifactorial, and Threshold disease. Periodontal disease is a highly prevalent dental disease, an almost 100% prevalence in developing countries.
- Conditions
- Gingivitis, Periodontitis, Aerosol Disease, Gingival Disease
- Trial name
- NCT03839719
- Testing
- Group PI, Group OC, Group CHX
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Government College of Dentistry, Indore
Infectious Keratitis, Microbial Keratitis
Use of a New Method for the Microbiological Diagnosis of Severe Corneal Infection
Microbial keratitis is a severe and often blindness-inducing pathology which represents today the first reason for long-term hospitalization (more than 5 days) in ophthalmology.
- Conditions
- Infectious Keratitis, Microbial Keratitis, Corneal Infection
- Trial name
- ABCORFILM (NCT05888987)
- Testing
- PCR multiplex by FilmArray
- Where
- France
- Volunteers
- 46 people
- Sponsor
- CHU de Reims
Bronchiectasis, Periodontal Disease
Evaluation of Periodontal Treatment in Patients With Bronchiectasis
Background: Association between periodontal disease (PD) and chronic obstructive pulmonary disease (COPD) has been widely studied and the aspiration of periodontal pathogens is one of the most accepted causal mechanisms for…
- Trial name
- NCT02514226
- Testing
- supragingival treatment, periodontal treatment, periodontal treatment and photodynamic therapy
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Nove de Julho
Acne Vulgaris
Acne Vulgaris Related Microbiology and Serology
This will be an investigation to determine the quality of the serological immune responses against Propionibacterium acnes (P. acnes) in acne patients compared to healthy individuals.
- Trial name
- NCT04056598
- Testing
- Study of humoral immunity
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sanofi
Deep Marginal Elevation, Periodontal Microenvironment
Deep Marginal Elevation and the Periodontal Microenvironment ( DME-PM )
This study aims to evaluate the impact of the dental restorative procedure known as Deep Marginal Elevation (DME) on periodontal health, including gingival and bone status, in patients with deep dental caries.
- Conditions
- Deep Marginal Elevation, Periodontal Microenvironment, Microbiological Study, Clinical Study
- Trial name
- NCT07156695
- Testing
- Deep Marginal Elevation (DME)
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Tanta University
Necrotizing Soft Tissue Infection, Fournier Gangrene
Necrotizing Soft Tissue Infections
SnapNSTI is an international, multicenter, time-bound prospective observational cohort study designed to characterize current epidemiology, management patterns, and outcomes of patients with necrotizing soft-tissue infections…
- Conditions
- Necrotizing Soft Tissue Infection, Fournier Gangrene, Sepsis, Surgical Infection
- Trial name
- SnapNSTI (NCT07107555)
- Where
- Spain
- Volunteers
- 480 people
- Sponsor
- European Society for Trauma and Emergency Surgery
Infection, Skin and Subcutaneous Tissue Bacterial Infections
Study of Accuracy of New Diagnostic Technology to Determine Guide Rapid Antibiotic Treatment for Serious Infections
Military service members and the U.S. veteran population face a growing and serious health threat: widespread antibiotic resistance resulting from resistant bacteria and a dwindling pipe-line of sufficiently potent antibiotics.
- Conditions
- Infection, Skin and Subcutaneous Tissue Bacterial Infections, Healthcare-associated Infection, Infection Due to Resistant Bacteria
- Trial name
- RAMPED (NCT02060513)
- Where
- 3 sites in United States
- Volunteers
- 2,298 people
- Sponsor
- Connie Price
Corynebacterium Diphtheriae Infection
Cutaneous Diphtheria in France : Observational, Retrospective Study of Patient Characteristics
Toxigenic cutaneous diphtheria is a notifiable disease that is re-emerging in the world and particularly in France. A better description of the epidemiological characteristics, as well as a refinement of the clinical…
- Trial name
- OEDIPE (NCT05798247)
- Testing
- Characteristics description
- Where
- 42 sites in France
- Volunteers
- 63 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Diabetes, Infection
Technology That Permits Focal Dose of Antibiotics to be Delivered to Lower Limb(s) of Diabetic Patients
The use of the Percutaneous Isolated Limb Procedure (PILP) which enables the use of existing antibiotic therapies in a more targeted and concentrated fashion in patients with diabetes who have a significant lower limb infection…
- Trial name
- NCT02158442
- Testing
- Percutaneous Isolated Limb Perfusion (PILP) delivery, Timentin
- Where
- Australia
- Volunteers
- 15 people
- Sponsor
- Osprey Medical, Inc
Abdominal Aorta Aneurism, Periodontitis
Clinical and Microbiological Relationships Between Periodontitis and Abdominal Aorta Aneurism: an Case Control Study
Aorta Abdominal aneurism (AAA) is a chronic degenerative disorder leading to the dilation and eventually to the rupture of the aortic wall.
- Conditions
- Abdominal Aorta Aneurism, Periodontitis, Dentulous
- Trial name
- NCT03767023
- Testing
- cross sectional
- Volunteers
- 61 people
- Sponsor
- University of Liege