Clinical trials: Microbiome
Bone Density, Gut Microbiomes
Linking Dietary Nutrition, Dietary Patterns, Gut Microbiota, and Bone Density: A Cross-Sectional Study
The study aims to understand the current situation of bone health in the Gannan Tibetan primary school student population, to explore the relationship between nutrition, intestinal microorganisms and bone health, to analyze the…
- Trial name
- NCT07256314
- Testing
- No Intervention: Observational Cohort
- Where
- China
- Volunteers
- 431 people, healthy volunteers welcome
- Sponsor
- Jianhua Ma
Disorder of Consciousness
Metabolic Abnormalities and Intestinal Microecology in Patients With Chronic Disorders of Consciousness
Following severe traumatic brain injury, patients may remain unconscious for many years. It is the intestinal microbiome and metabolomics analysis comparing differentially intestinal microflora and metabolites between patients…
- Trial name
- NCT04530968
- Testing
- No intervention
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Zhejiang University
Healthy
The Effect of Grape Consumption on Increasing the Good Bacteria in the Human Intestine
This pilot study will assess the ability of daily consumption of one dose (2 servings) of freeze-dried whole table grape powder, made from conventionally grown grapes to alter the composition of the bacteria that live in the…
- Trial name
- NCT05025189
- Testing
- Table Grape Powder, Beige Diet
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Gut Microbiome
Neonatal Microbiome Validity Study
This is a validation study to compare proposed field collection methods with a gold standard collection technique for microbiome analysis of stool and breast milk samples.
- Trial name
- NCT02655250
- Testing
- Microbiome
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Diet Intervention
Effects of Almond Consumption on Cardiovascular, Metabolomic, and Microbiome Profiles in Millennials
The purpose of the study is to examine the effects of almond snacking on metabolic, cardiovascular and microbiome profiles in college freshmen.
- Trial name
- NCT03084003
- Testing
- Almonds, Graham crackers
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- University of California, Merced
Health of the Human Microbiome
Dogs as Probiotics
Studies show that family members share as much or more of the composition of their microbiota (the trillions of micro-organisms in our guts) with their dogs as they do with each other (Song et. al. 2013).
- Trial name
- NCT02343731
- Testing
- Introduction of a dog into the home
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Breast Feeding, Human Microbiome
Human Milk and Infant Intestinal Microbiome Study
This study will explore the effects of skin-to-skin contact (SSC) between mothers and their babies on the infant intestinal microbiome, the maternal skin microbiome and the breast milk microbiome.
- Trial name
- NCT03181269
- Testing
- Intervention education
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Mechanisms, Defense
The Effect of Concord Grape Polyphenol-soy Protein Isolate Complex (GP-SPI) on Gut Microbiota
The overall purpose of this study is to evaluate the effect of nutritional supplementation with a well-characterized preparation of Concord grape polyphenol-soy protein isolate (GP-SPI) on the composition of the gut microbiota.
- Trial name
- NCT04018066
- Testing
- GP-SPI
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Recurrent Pregnancy Loss, Not Pregnant, Vaginal Microbiome
Uterine Microbiome in Recurrent Pregnancy Loss
The female genital tract microbiome may reflect female reproductive health and may be related to pregnancy outcomes. Disturbances in this microbiome may be associated with adverse reproductive outcomes.
- Trial name
- NCT05510622
- Testing
- Vaginal swab and endometrial biopsy
- Where
- 2 sites in Vietnam
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mỹ Đức Hospital
Human Microbiome
A Clinical Trial for Analysis of Intestinal Microbiome Affecting PK, PD, and Safety of Metformin
This clinical trial is intended to evaluate the effects of the changes in intestinal microbiome by antibiotics (PO vancomycin) on the pharmacokinetic /pharmacodynamic and safety profiles of metformin in healthy male volunteers.
- Trial name
- NCT03809260
- Testing
- Metformin (part 1), Vancomycin, Metformin (part 2)
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Dietary Habits
Analysis of MicroBial Metabolites After Eating Refined Food
The purpose of this study is to learn more about what happens in the human body after consuming a meal that contains ultra-processed foods like hamburgers, and if this is different to what happens after consuming a meal that…
- Trial name
- AMBER (NCT04308473)
- Testing
- Ultra-processed Food Meal, Whole Food Meal
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Lung Cancer
Oral Microbiome Diagnostics of Lung Cancer
The study aims to develop a deep learning-based diagnostic method for lung cancer using the oral microbiome. This innovative approach involves establishing an observational cohort of 576 individuals, including lung cancer…
- Trial name
- NCT06270992
- Testing
- NCCN (National Comprehensive Cancer Network) diagnosis
- Where
- Turkey (Türkiye)
- Volunteers
- 676 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Poor Sleep Quality, Gut Microbiome
The Impact of Overnight Active Temperature Regulation on the Gut Microbiome, Inflammation, and Circadian Rhythm.
This study examines whether two continuous weeks of overnight active temperature regulation (via the Eight Sleep Pod) use affects gut microbiome composition, inflammation, and the body's daily temperature and blood pressure…
- Conditions
- Poor Sleep Quality, Gut Microbiome, Gut Health, Inflammation
- Trial name
- NCT07848594
- Testing
- Overnight Active Temperature Regulation: Eight Sleep Pod System
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eight Sleep Inc.
Host and Microbiome, Pregnancy Outcomes
Human Genes and Microbiota in Early Life
The long-term goal of the Human Genes and Microbiota in Early Life (HuGME) is to explore the short- and long-term effects of maternal microbiota during pregnancy and the microbiota colonization of their offspring early in life…
- Conditions
- Host and Microbiome, Pregnancy Outcomes, Pregnancy Complications, Neurodevelopmental Disorders
- Trial name
- HuGME (NCT06926166)
- Testing
- No intervention
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Obesity
Dairy Intervention in People With Obesity
Obesity is associated with increased morbidity and mortality, but weight reduction is difficult to achieve. In this randomized controlled trial we will include 120 obese subjects.
- Trial name
- DIPO (NCT04154475)
- Testing
- yogurt diet, dairy diet, standard diet
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Hypertension
The Role of Gut Microbiota in Hypertension
Hypertension is the single most prevalent risk factor for heart diseases, heart failure, kidney failure and stroke. About 1 in 3 adults in the United States have hypertension.
- Trial name
- NCT02188381
- Testing
- Stool Sample and Blood Sample
- Where
- United States
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- University of Florida
Periodontitis Stage IV, Periodontitis
Microbiological Modulation Of The Oral-Gut Axis After Treatment With Or Without Systemic Use Of Probiotics In Patients With Periodontitis: A Randomized Controlled Clinical Study.
This study aims to evaluate whether the oral administration of probiotics, in combination with conventional periodontal treatment (deep cleaning of the tooth root surfaces), can improve oral health and influence the relationship…
- Trial name
- NCT07792902
- Testing
- Probiotics Bifidobacterium animalis subsp. lactis HN019
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Healthy Skin
Effect of Surfactants on the Skin Microbiome
Up to 10 volunteers will be recruited to evaluate the microbial environment on their forearms. Following informed consent, bacterial swabs will be obtained at baseline from the forearms of all subjects.
- Trial name
- NCT01951391
- Testing
- Control Hand Soap, Benzalkonium Chloride Soap, Triclocarban Soap
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
ADHD, ADHD - Attention Deficit Disorder With Hyperactivity
Developing Microbiome and Dietary Strategies Based on Chrono-nutrition for Targeting ADHD
Study objectives This project seeks to understand how an intervention based on time-restricted eating (ChronoFeeding or CF) can improve quality of life, behavior, sleep, and gut health in adults with ADHD (Attention Deficit…
- Trial name
- CronoNutriBiom (NCT07821060)
- Testing
- Circadian fasting
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Spanish National Research Council
Gut Microbiome, Skin Microbiome
The Influence of Oral Probiotics on the Microbiome and Lipidome
The purpose of this study is to measure oil production of the face, facial properties, and gut bacteria in people being given oral probiotics.
- Conditions
- Gut Microbiome, Skin Microbiome, Gut Lipidome, Skin Lipidome
- Trial name
- NCT03605108
- Testing
- Probiotic
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.