Clinical trials: Microsurgical, open to volunteers
Brain Arteriovenous Malformation
Registry of Multimodality Treatment for Brain Arteriovenous Malformation in Mainland China
This study is a multi-center, prospective, registry study. This research was supported by the National Key Research and Development Program.
- Trial name
- MATCH (NCT04572568)
- Testing
- Multi-disciplinary assessment
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Tiantan Hospital
Degenerative Lumbar Canal Stenosis
Comparison Between The Results of Open and Microsurgical Decompression in Degenerative Spinal Canal Stenosis in Lumbar Spine
To compare the outcomes of open and microsururgical decompression in degenerative spinal stenosis in lumbar spine
- Trial name
- NCT06722859
- Testing
- Open surgical decompression in degenerative lumbar canal stenosis, Microsurgical decompression
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Assiut University
Bilateral Varicocele, Male Infertility
Single Infrapubic Versus Bilateral Subinguinal Microsurgical Varicocelectomy
Bilateral varicocele is commonly treated by microsurgical varicocelectomy. The conventional bilateral subinguinal approach usually requires two separate skin incisions, one on each side.
- Trial name
- NCT07650955
- Testing
- Single Infrapubic Microsurgical Bilateral Varicocelectomy, Bilateral Subinguinal Microsurgical Varicocelectomy
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Beni-Suef University
LUMBAR STENOSIS
Pain After Microsurgical Decompression
This prospective observational cohort study aims to determine whether a combination of preoperative clinical, psychological, sleep-related, inflammatory, genetic, and epigenetic factors can predict chronic postoperative pain 12…
- Trial name
- NCT07883694
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Aalborg University
Brain Neoplasms, Meningioma
Preoperative Embolization for Highly Vascular Brain Tumors
Highly vascular brain tumors, including meningiomas, hemangioblastomas, and certain metastases, have a rich blood supply that can lead to substantial blood loss and technical difficulties during surgical removal.
- Conditions
- Brain Neoplasms, Meningioma, Hemangioblastoma, Brain Metastases
- Trial name
- NCT07823985
- Testing
- Preoperative Endovascular Embolization
- Volunteers
- 55 people
- Sponsor
- Assiut University
Corneal Dystrophy
Microsurgical Robot-assisted Corneal Transplant
Full-thickness corneal grafting (transfixing keratoplasty) is a tissue graft described at the beginning of the 20th century, which has remained technically unchanged for several decades.
- Trial name
- GRACE (NCT06844123)
- Testing
- Robot-assisted keratoplasty
- Where
- France
- Volunteers
- 10 people
- Sponsor
- CHU de Reims
Alzheimer Disease, Lymphatic Obstruction
Robotic-Enabled Microsurgical Intervention for Neurodegenerative Disease
The objective of this investigational device exemption (IDE) study is to evaluate the safety and feasibility of using the Symani System and microsurgical techniques in the deep cervical lymph node (dCLN) region in the setting of…
- Trial name
- REMIND (NCT07178210)
- Testing
- Symani Surgical System
- Where
- 3 sites in United States
- Volunteers
- 15 people
- Sponsor
- MMI (Medical Microinstruments, Inc.)
Alzheimer's
Robotic-Enabled Microsurgical Intervention for Neurodegenerative Disease - EU
The objective of this study is to evaluate the safety and feasibility of the Symani System and microsurgical techniques in the deep Cervical Lymph Node (dCLN) region in patients with confirmed Alzheimer's disease.
- Trial name
- REMIND-EU (NCT07708675)
- Testing
- Symani Surgical System
- Volunteers
- 50 people
- Sponsor
- MMI (Medical Microinstruments, Inc.)
Lymphedema, Mastectomy
Primary Surgical Prevention of Breast Cancer-related Lymphedema
Lymphedema refers to edema caused by insufficient drainage of interstitial fluid through the lymphatic circulation system. It occurs mainly in the upper and lower extremities and causes chronic inflammation, and finally fibrous…
- Conditions
- Lymphedema, Mastectomy, Breast Cancer
- Trial name
- LYMPHA (NCT04687956)
- Testing
- LYMPHA, control
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Gangnam Severance Hospital
Varicocele, Male Infertility
Selective Extended Venous Stripping Versus Standard Microsurgical Varicocelectomy for Varicocele-Related Male Infertility
Varicocele is a common correctable cause of male infertility and may be associated with abnormal semen parameters, impaired testicular function, and scrotal discomfort.
- Trial name
- NCT07605351
- Testing
- Microsurgical Subinguinal Varicocelectomy With Selective Extended Venous Stripping, Standard Microsurgical Subinguinal Varicocelectomy With Conventional Vein Ligation
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Benha University
Periodontal Diseases
Microsurgery and Periodontal Healing
Scientists do research to answer important questions which might help change or improve the way we do things in the future. The investigators know that using glasses with special attachments that provide magnification (dental…
- Trial name
- NCT07054008
- Testing
- Microsurgical approach with Digital Microscope
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
DIEP Flap, Breast Reconstruction
ORASIS in Breast Reconstruction
The purpose of this study is to assess the use of ORASIS during microsurgical anastomosis formation in Deep Inferior Epigastric Perforator (DIEP) flap breast reconstruction and its potential effects on surgical precision, surgeon…
- Conditions
- DIEP Flap, Breast Reconstruction, Breast Cancer
- Trial name
- NCT07670754
- Testing
- Use of ORASIS Device
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Duke University
Intracerebral Hemorrhage Lobar
Evacuation of Lobar Intracranial Hemorrhage Using Microsurgical Technique (ELIMINATE)
ELIMINATE is a cohort study, phase 2A, designed to determine whether a standardized microsurgical procedure to evacuate spontaneous lobar intracranial hemorrhage (ICH) is feasible, safe and surgically efficacious in achieving a…
- Trial name
- ELIMINATE (NCT07697742)
- Testing
- Microsurgical hematoma evacuation
- Where
- Canada
- Volunteers
- 27 people
- Sponsor
- Dr. Michael D Hill
Alzheimer Disease
Cervical Lymphatic Microsurgery in Alzheimer's Disease
This pilot study will evaluate whether microsurgical modification of cervical lymphatic drainage may influence blood biomarkers and clinical outcomes in people with mild Alzheimer's disease.
- Trial name
- NCT07857759
- Testing
- Cervical Lymphatic Microsurgery
- Where
- 2 sites in Poland
- Volunteers
- 30 people
- Sponsor
- Daniel Maliszewski
Brain Neoplasms, Eloquent Area Brain Tumors
CONNEctome-guided Navigation for Eloquent-area Tumor Surgery Trial
This study is designed for patients with brain tumors located in eloquent brain areas involved in language, motor, or major functional brain networks.
- Trial name
- CONNECT Trail (NCT07657403)
- Testing
- Connectome-Guided Navigation-Assisted Microsurgical Resection, Conventional DTI Tractography-Guided Tumor Resection
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Microsurgical, Single Dartos Flap
Microsurgical Single Versus Double Dartos Flap in Distal Hypospadias Repair
This study aims to compare the surgical and functional outcomes of microsurgical single dartos flap versus double dartos flap in distal hypospadias repair.
- Conditions
- Microsurgical, Single Dartos Flap, Double Dartos Flap, Distal Hypospadias Repair
- Trial name
- NCT07676916
- Testing
- Microsurgical Single Dartos Flap, Microsurgical Double Dartos Flap
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Tanta University
Bone Loss, Bone Loss, Age-related
Minimally Invasive Sinus Lift Through the Interradicular Septum
This study aims to describe a new approach for the reconstruction of the alveolar process in the sinus area. This minimally invasive approach will access the maxillary sinus through the alveolar process, elevating the sinus…
- Conditions
- Bone Loss, Bone Loss, Age-related, Atrophy; Alveolar Process, Surgical Procedure, Unspecified
- Trial name
- NCT05237570
- Testing
- Interradicular septum window
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad de Murcia
Lymphedema, Breast Cancer
The LYMPH Trial - Microsurgical Versus Conservative Treatment of Chronic Breast Cancer Associated Lymphedema
The aim of this study is to test whether lymphatic surgery provides better QoL (assessed with the Lymph-ICF-UL, (Lymphedema Functioning Disability and health questionnaire for upper limb lymphedema)) 15 months after randomization…
- Trial name
- LYMPH (NCT05890677)
- Testing
- Surgical Intervention, Conservative Complex Physical Decongestion Therapy
- Where
- 36 sites in United States, Austria and 13 more
- Volunteers
- 280 people
- Sponsor
- University Hospital, Basel, Switzerland
Anastomosis, Surgical
Evaluation of MUSA-3 in Microsurgical Anastomoses
This study is conducted to evaluate the safety and performance of robot-assisted microsurgical anastomoses with the MUSA-3 system.
- Trial name
- NCT07427823
- Testing
- Robot-assisted microsurgical anastomoses
- Volunteers
- 30 people
- Sponsor
- Microsure
Subarachnoid Aneurysm Hemorrhage, Microsurgery
Structural and Clinical Predictors of Cognitive Impairment After Surgical Treatment for Ruptured Cerebral Aneurysms
This study investigates the clinical and structural predictors of long-term cognitive impairment in patients who underwent microsurgical clipping for aneurysmal subarachnoid hemorrhage.
- Conditions
- Subarachnoid Aneurysm Hemorrhage, Microsurgery, Cognitive Impairment
- Trial name
- SCOPE-aSAH (NCT07723131)
- Where
- Brazil
- Volunteers
- 150 people
- Sponsor
- University of Campinas, Brazil