Clinical trials: Microwave
Cancer of Kidney
Microwave Coagulation in Partial Nephrectomy Protocol
Partial nephrectomy (kidney removal) is a standard therapy for clinical T1 renal (kidney) tumors. The goals of surgery are to accurately remove the tumor with no cancer cells at the edge of the remaining tissue, to limit blood…
- Trial name
- NCT01931462
- Testing
- Microwave pre-coagulation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Wisconsin, Madison
Atrial Fibrillation
Prospective Clinical Study of the Guidant Microwave Ablation System for the Treatment of PAF in the MIS Procedure
The purpose of this prospective, single-arm, un-blinded, multi-site clinical study is to assess the safety and efficacy of the Microwave Ablation System for the treatment of symptomatic paroxysmal atrial fibrillation (PAF) in the…
- Trial name
- NCT00415558
- Testing
- Microwave Ablation System
- Where
- 5 sites in United States
- Sponsor
- Maquet Cardiovascular
HCC
Small and Steatotic Hepatocellular Carcinoma
Percutaneous thermoablation in an effective local curative treatment in patients with cirrhosis and HCC smaller than 3 cm in diameter (BCLC 0-A).
- Trial name
- NCT03428321
- Where
- France
- Volunteers
- 238 people
- Sponsor
- University Hospital, Montpellier
Liver Cancer (Primary and Metastatic), Lung Cancer (Diagnosis)
Registry of Minimally Invasive Cancer Treatment Using Spectral Angio-CT Image Guidance
This study collects data from patients undergoing minimally invasive, image-guided cancer treatments at participating hospitals in the Netherlands and France.
- Conditions
- Liver Cancer (Primary and Metastatic), Lung Cancer (Diagnosis), Bone Cancer Metastatic, Bone Cancer Tumor
- Trial name
- PreciseOnco (NCT07636148)
- Where
- 3 sites in France, Netherlands
- Volunteers
- 2,000 people
- Sponsor
- Mark C Burgmans, MD PhD
Hepatocellular Carcinoma (HCC)
Comparison of the Therapeutic Efficacy of Non-touch Microwave Ablation, Tumor-puncture Microwave Ablation and Surgical Resection for Subcapsular Hepatocellular Carcinoma
Subcapsular hepatocellular carcinoma (HCC) has unique anatomical characteristics that may influence treatment selection and clinical outcomes.
- Trial name
- NCT07748481
- Testing
- No-touch Microwave Ablation, Tumor-puncture Microwave Ablation, Surgical Resection
- Volunteers
- 180 people
- Sponsor
- The First Hospital of Jilin University
Prostate Cancer Stage I
Targeted Microwave Focal Therapy
Focal therapy (FT) for prostate cancer (PCa) is an interesting therapeutic option for localized disease with a favorable low- to intermediate-risk profile.
- Trial name
- NCT04627896
- Testing
- Katty focal therapy
- Where
- Italy
- Volunteers
- 11 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Regional Anesthesia, Pain Control
CMRA for US-guided-MWA of Liver Tumors
Patients with liver tumors who underwent US-guided-MWA of liver tumors were enrolled. These patients were allocated into three groups based on tumor size and number: A, B, and C.
- Conditions
- Regional Anesthesia, Pain Control, Microwave Ablation, Liver Tumors
- Trial name
- NCT05990257
- Testing
- HHB+TAPB+and LA, HHB+LA, TAPB+LA
- Where
- China
- Volunteers
- 122 people
- Sponsor
- Lu Wang
Hyperhidrosis Primary Focal Axilla
Longevity of Microwave Thermolysis and Botulinum Toxin A for Treatment of Axillary Hyperhidrosis
This trial aims is to assess and compare treatment effect of microwave thermolysis and botulinum toxin A for axillary hyperhidrosis with focus on longevity.
- Trial name
- NCT05057117
- Testing
- Microwave thermolysis, Botulinum toxin A
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Merete Haedersdal
Varicose Veins of Lower Limb, Venous Insufficiency of Leg
Comparative Analysis of Radiofrequency Ablation and Microwave Ablation Procedures for the Treatment of Small Saphenous Varicose Veins
Objective: To investigate the clinical efficacy of ultrasound-guided radiofrequency ablation and microwave ablation in the treatment of primary saphenous varicose veins.
- Conditions
- Varicose Veins of Lower Limb, Venous Insufficiency of Leg, Vascular Disease，Peripheral
- Trial name
- NCT06711120
- Testing
- Radiofrequency ablation and microwave ablation are used to treat small saphenous varicose veins, respectively
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Lung Cancer (NSCLC)
MWA With or Without Furmonertinib for Early-Stage Non-Small Cell Lung Cancer
This is a single-center randomized trial that investigates microwave ablation (MWA) combined with EGFR-TKI therapy in 120 early-stage NSCLC patients (T1-T2N0M0, EGFR-mutant) unsuitable for standard treatments.
- Trial name
- NCT06969781
- Testing
- MWA, TKI
- Volunteers
- 120 people
- Sponsor
- Shanghai Chest Hospital
Prostate Cancer
Prospective Asian Multicenter Prostate Cancer Focal Therapy Study (ProAMFocal)
This is a multicenter observational study of patients undergoing focal therapy for prostate cancer in Asia
- Trial name
- ProAMFocal (NCT06491056)
- Testing
- Focal Therapy for Prostate Cancer
- Where
- Singapore
- Volunteers
- 500 people
- Sponsor
- Singapore General Hospital
Solid Tumor
A Study of Microwave Ablation Combined With Immunotherapy ± Anti-angiogenic Drugs in the Treatment of Solid Tumors
This is a multi-center, phase Il trial to evaluate the efficacy and safety of microwave ablation combined with immunotherapy ± anti-angiogenic drugs in the treatment of advanced second-line and above solid tumors.
- Trial name
- NCT06537505
- Testing
- Adebrelimab, Apatinib, microwave ablation
- Volunteers
- 60 people
- Sponsor
- Beidahuang Industry Group General Hospital
Breast Cancer Stage I
Non Surgical Treatment (Microwave Ablation) of Breast Cancer
In the Netherlands approximately one out of seven women will develop breast cancer during her life. Most of these breast cancers are early stage, 40% of the women have stage 1.
- Trial name
- MASTER (NCT05887154)
- Testing
- Microwave ablation
- Volunteers
- 15 people
- Sponsor
- University Medical Center Groningen
Hepatocellular Carcinoma, Immune Response
Immunological Response After Ablative Therapy in the Liver
Local ablative treatment of Hepatocellular Carcinoma is performed primary on patients not eligible for liver transplant or liver resection.
- Trial name
- IRAL (NCT03040453)
- Testing
- Microwave ablation, Irreversible electroporation
- Where
- Sweden
- Sponsor
- Karolinska Institutet
Stroke, Acute, Intracerebral Hemorrhage
Mobile Microwave-based Diagnosis and Monitoring of Stroke
This is a prospective, open, multicentre trial that will enrol patients with clinical signs of stroke in the acute phase admitted for CT scan. The study assesses the diagnostic capability and safety of Strokefinder MD100.
- Trial name
- MODS (NCT04257149)
- Testing
- Hemorrhagic stroke group (group A), Ischemic stroke group (group B), Stroke mimic group (group C)
- Where
- 4 sites in Norway
- Volunteers
- 500 people
- Sponsor
- Helse Stavanger HF
Lung Neoplasms, Cancer of Lung
MARK 1A Series: Percutaneous Microwave Ablation for Patients With Lung Tumor(s)
Does lung ablation improve clinical outcomes for patients deemed to be surgically high-risk?
- Conditions
- Lung Neoplasms, Cancer of Lung, Cancer of the Lung, Lung Cancer
- Trial name
- MARK 1A (NCT02673021)
- Testing
- Microwave ablation
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Mayo Clinic
Adenomyosis of Uterus
Evaluation of the Efficacy and Safety of Microwave Ablation of Uterine Adenomyosis Under Improved Ultrasound Guidance
This study aims to compare the safety and efficacy of segmental power adjustment combined with uterine cavity hydro-isolation in microwave ablation of adenomyosis
- Trial name
- NCT06751264
- Testing
- Peritoneal combined with intrauterine water isolation, Peritoneal water isolation
- Where
- China
- Volunteers
- 137 people
- Sponsor
- Peking University Aerospace Center Hospital
Lung Cancer
Bronchoscopic Microwave Ablation of Lung Tissue
The primary purpose of this study is to evaluate the safety and feasibility of the Creo Medical MicroBlate™ Flex AB1 instrument used with the AB1 electrosurgical system in patients undergoing bronchoscopic microwave ablation of…
- Trial name
- AB1MALT (NCT05786625)
- Testing
- Ablation
- Where
- 2 sites in Netherlands, United Kingdom
- Volunteers
- 35 people
- Sponsor
- Creo Medical Limited
Lung Non-Small Cell Carcinoma, Metastatic Colorectal Carcinoma
Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME Study
This study compares the outcomes and safety of two standard treatment options called microwave ablation and surgical wedge resection in patients with non-small cell lung cancer, sarcoma and colorectal cancer that has spread to…
- Conditions
- Lung Non-Small Cell Carcinoma, Metastatic Colorectal Carcinoma, Metastatic Sarcoma, Stage I Lung Cancer AJCC v8
- Trial name
- NCT04430725
- Testing
- Computed Tomography with Contrast, Microwave Ablation, Questionnaire Administration
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- M.D. Anderson Cancer Center
Hepatocellular Carcinoma, Microwave Ablation
Role of Perfluorobutane in Lesion Detection, Targeting and Response Assessment for Ablation of HCC
Primary liver cancers are the sixth most common malignancies worldwide, with hepatocellular carcinoma (HCC) accounting for approximately 80% of them.
- Trial name
- NCT05068076
- Testing
- Perfluorobutane
- Where
- India
- Volunteers
- 21 people
- Sponsor
- Institute of Liver and Biliary Sciences, India